DNMT1 Mediates Chronic Pain-Related Depression by Inhibiting GABAergic Neuronal Activation in the Central Amygdala. | DNMT1 Mediates Chronic Pain-Related Depression by Inhibiting GABAergic Neuronal Activation in the Central Amygdala. Ding X, Lin Y, Chen C, Yan B, Liu Q, Zheng H, Wu Y, Zhou C. | 09/20/2023 |
DNMT1-induced miR-133b suppression via methylation promotes myocardial fibrosis after myocardial infarction. | DNMT1-induced miR-133b suppression via methylation promotes myocardial fibrosis after myocardial infarction. Zhang S, Xie H, Du Y, Wang B, Lan B, Wang H. | 09/15/2023 |
DNMT1 involved in the analgesic effect of folic acid on gastric hypersensitivity through downregulating ASIC1 in adult offspring rats with prenatal maternal stress. | DNMT1 involved in the analgesic effect of folic acid on gastric hypersensitivity through downregulating ASIC1 in adult offspring rats with prenatal maternal stress. Wang HJ, Zhang FC, Xu TW, Xu YC, Tian YQ, Wu YY, Xu JT, Hu S, Xu GY., Free PMC Article | 08/25/2023 |
DNMT1 regulates polarization of macrophage-induced intervertebral disc degeneration by modulating SIRT6 expression and promoting pyroptosis in vivo. | DNMT1 regulates polarization of macrophage-induced intervertebral disc degeneration by modulating SIRT6 expression and promoting pyroptosis in vivo. Hou Y, Shi J, Guo Y, Shi G., Free PMC Article | 06/15/2023 |
Runt-related transcription factor 3, mediated by DNA-methyltransferase 1, regulated Schwann cell proliferation and myelination during peripheral nerve regeneration via JAK/STAT signaling pathway. | Runt-related transcription factor 3, mediated by DNA-methyltransferase 1, regulated Schwann cell proliferation and myelination during peripheral nerve regeneration via JAK/STAT signaling pathway. Wu Q, Xie J, Zhu X, He J. | 06/14/2023 |
LncRNA XR_351665 Contributes to Chronic Pain-Induced Depression by Upregulating DNMT1 via Sponging miR-152-3p. | LncRNA XR_351665 Contributes to Chronic Pain-Induced Depression by Upregulating DNMT1 via Sponging miR-152-3p. Ding X, Lin Y, Yan B, Jiao X, Liu Q, Miao H, Wu Y, Zhou C. | 03/13/2023 |
A Paternal Methylation Error in the Congenital Hydrocephalic Texas (H-Tx) Rat Is Partially Rescued with Natural Folate Supplements. | A Paternal Methylation Error in the Congenital Hydrocephalic Texas (H-Tx) Rat Is Partially Rescued with Natural Folate Supplements. Naz N, Moshkdanian G, Miyan S, Eljabri S, James C, Miyan J., Free PMC Article | 02/4/2023 |
RNA interference-mediated silencing of DNA methyltransferase 1 attenuates neuropathic pain by accelerating microglia M2 polarization. | RNA interference-mediated silencing of DNA methyltransferase 1 attenuates neuropathic pain by accelerating microglia M2 polarization. Tan Y, Wang Z, Liu T, Gao P, Xu S, Tan L., Free PMC Article | 10/8/2022 |
DNA methyltransferase 1 (DNMT1) suppresses mitophagy and aggravates heart failure via the microRNA-152-3p/ETS1/RhoH axis. | DNA methyltransferase 1 (DNMT1) suppresses mitophagy and aggravates heart failure via the microRNA-152-3p/ETS1/RhoH axis. Deng Z, Yao J, Xiao N, Han Y, Wu X, Ci C, Chen K, Geng X. | 07/30/2022 |
DNMT1-Induced miR-152-3p Suppression Facilitates Cardiac Fibroblast Activation in Cardiac Fibrosis. | DNMT1-Induced miR-152-3p Suppression Facilitates Cardiac Fibroblast Activation in Cardiac Fibrosis. Xu SS, Ding JF, Shi P, Shi KH, Tao H. | 02/26/2022 |
Histone deacetylase 3 suppresses the expression of SHP-1 via deacetylation of DNMT1 to promote heart failure. | Histone deacetylase 3 suppresses the expression of SHP-1 via deacetylation of DNMT1 to promote heart failure. Wang YY, Gao B, Yang Y, Jia SB, Ma XP, Zhang MH, Wang LJ, Ma AQ, Zhang QN. | 02/12/2022 |
Histone Methyltransferases SUV39H1 and G9a and DNA Methyltransferase DNMT1 in Penumbra Neurons and Astrocytes after Photothrombotic Stroke. | Histone Methyltransferases SUV39H1 and G9a and DNA Methyltransferase DNMT1 in Penumbra Neurons and Astrocytes after Photothrombotic Stroke. Sharifulina S, Dzreyan V, Guzenko V, Demyanenko S., Free PMC Article | 12/25/2021 |
DNMT1 deregulation of SOCS3 axis drives cardiac fibroblast activation in diabetic cardiac fibrosis. | DNMT1 deregulation of SOCS3 axis drives cardiac fibroblast activation in diabetic cardiac fibrosis. Tao H, Shi P, Zhao XD, Xuan HY, Gong WH, Ding XS. | 10/2/2021 |
DNMT1 Methylation of LncRNA GAS5 Leads to Cardiac Fibroblast Pyroptosis via Affecting NLRP3 Axis. | DNMT1 Methylation of LncRNA GAS5 Leads to Cardiac Fibroblast Pyroptosis via Affecting NLRP3 Axis. She Q, Shi P, Xu SS, Xuan HY, Tao H, Shi KH, Yang Y. | 04/3/2021 |
DNMT1-mediated lncRNA MEG3 methylation accelerates endothelial-mesenchymal transition in diabetic retinopathy through the PI3K/Akt/mTOR signaling pathway. | DNMT1-mediated lncRNA MEG3 methylation accelerates endothelial-mesenchymal transition in diabetic retinopathy through the PI3K/Akt/mTOR signaling pathway. He Y, Dan Y, Gao X, Huang L, Lv H, Chen J. | 03/28/2021 |
Epigenetics and Mitochondrial Stability in the Metabolic Memory Phenomenon Associated with Continued Progression of Diabetic Retinopathy. | Epigenetics and Mitochondrial Stability in the Metabolic Memory Phenomenon Associated with Continued Progression of Diabetic Retinopathy. Kowluru RA, Mohammad G., Free PMC Article | 12/5/2020 |
DNA methyltransferase-1 inactivation of androgen receptor axis triggers homocysteine induced cardiac fibroblast autophagy in diabetic cardiac fibrosis. | DNA methyltransferase-1 inactivation of androgen receptor axis triggers homocysteine induced cardiac fibroblast autophagy in diabetic cardiac fibrosis. Tao H, Shi P, Xuan HY, Ding XS. | 11/21/2020 |
Myocardial tissue-specific Dnmt1 knockout in rats protects against pathological injury induced by Adriamycin. | Myocardial tissue-specific Dnmt1 knockout in rats protects against pathological injury induced by Adriamycin. Wu TT, Ma YW, Zhang X, Dong W, Gao S, Wang JZ, Zhang LF, Lu D., Free PMC Article | 10/24/2020 |
The authors report that DNMT1 expression and lncRNA-H19 methylation are upregulated in the femoral tissues of disuse osteoporosis rats, accompanied with inhibited Erk signaling pathway. | Overexpression of DNMT1 leads to hypermethylation of H19 promoter and inhibition of Erk signaling pathway in disuse osteoporosis. Li B, Zhao J, Ma JX, Li GM, Zhang Y, Xing GS, Liu J, Ma XL. | 03/23/2019 |
DNMT1 is the downstream target of the mTOR pathway and mediates the mTOR pathway inhibition-induced reduction in NGF expression in Schwann cells | DNMT1, a Novel Regulator Mediating mTORC1/mTORC2 Pathway-Induced NGF Expression in Schwann Cells. Cheng M, Lv X, Zhang C, Du W, Liu Y, Zhu L, Hao J. | 12/22/2018 |
A novel mechanism of DNA methylation mediated by DNMT1 in prevention of Hcy associated cardiovascular disease. | Homocysteine inhibits endothelial progenitor cells proliferation via DNMT1-mediated hypomethylation of Cyclin A. Zhang HP, Wang YH, Ma SC, Zhang H, Yang AN, Yang XL, Zhang MH, Sun JM, Hao YJ, Jiang YD. | 09/8/2018 |
hypomethylation of FABP4 was regulated by DNMT1, which was a direct target of miR-152/148a, in pre-eclampsia model | Modulation of FABP4 hypomethylation by DNMT1 and its inverse interaction with miR-148a/152 in the placenta of preeclamptic rats and HTR-8 cells. Yang A, Zhang H, Sun Y, Wang Y, Yang X, Yang X, Zhang H, Guo W, Zhu G, Tian J, Jia Y, Jiang Y. | 10/14/2017 |
DNMT1 activates the canonical Wnt signaling in rheumatoid arthritis model rats via a crucial functional crosstalk between miR-152 and the DNMT1, MeCP2 | DNMT1 activates the canonical Wnt signaling in rheumatoid arthritis model rats via a crucial functional crosstalk between miR-152 and the DNMT1, MeCP2. Miao CG, Qin D, Du CL, Ye H, Shi WJ, Xiong YY, Zhang XL, Yu H, Dou JF, Ma ST, Qin MS, Liu HZ, Fang YX, Zhou GL, Chen JZ, He X, Huang C, Huang Y, Zhang B, Song TW, Li J. | 07/2/2016 |
Results identify LRRFIP1, SMARCA4, and DNMT1 as novel regulators of macrophage multinucleation. | Integrating phosphoproteome and transcriptome reveals new determinants of macrophage multinucleation. Rotival M, Ko JH, Srivastava PK, Kerloc'h A, Montoya A, Mauro C, Faull P, Cutillas PR, Petretto E, Behmoaras J., Free PMC Article | 12/5/2015 |
Acute restraint stress evokes adaptive changes in global DNA methylation of rat brain that are independent of the expression of the Dnmt1 gene but might be linked to abnormal expression of the Bdnf gene in the PAG. | Acute stress affects the global DNA methylation profile in rat brain: modulation by physical exercise. Rodrigues GM Jr, Toffoli LV, Manfredo MH, Francis-Oliveira J, Silva AS, Raquel HA, Martins-Pinge MC, Moreira EG, Fernandes KB, Pelosi GG, Gomes MV. | 08/22/2015 |