| CircBCAR3 sponges miR-27a-3p and mediates ferroptosis in human B-prolymphocytic leukaemia cells via SLC7A11. | CircBCAR3 sponges miR-27a-3p and mediates ferroptosis in human B-prolymphocytic leukaemia cells via SLC7A11.
Zhao G, Chen H, Luo J. | 01/5/2024 |
| Comprehensive immunohistochemical analysis of RET, BCAR1, and BCAR3 expression in patients with Luminal A and B breast cancer subtypes. | Comprehensive immunohistochemical analysis of RET, BCAR1, and BCAR3 expression in patients with Luminal A and B breast cancer subtypes.
Pavanelli AC, Mangone FR, Yoganathan P, Bessa SA, Nonogaki S, de Toledo Osório CAB, de Andrade VP, Soares IC, de Mello ES, Mulligan LM, Nagai MA. | 02/19/2022 |
| A Cas-BCAR3 co-regulatory circuit controls lamellipodia dynamics. | A Cas-BCAR3 co-regulatory circuit controls lamellipodia dynamics.
Steenkiste EM, Berndt JD, Pilling C, Simpkins C, Cooper JA., Free PMC Article | 10/9/2021 |
| MIG-7 mRNA expression may serve as an additional molecular marker of vasculogenic mimicry in ovarian malignancies. | Mig-7 expression and vasculogenic mimicry in malignant ovarian tumors.
Czekierdowski A, Czekierdowska S, Stachowicz N, Łoziński T, Gurynowicz G. | 01/20/2021 |
| Study provides evidence that MIG7 expression in hepatocellular carcinoma (HCC) tissue is correlated positively with vasculogenic mimicry (VM) formation and MIG7 expression in different HCC cell lines is coincident with their VM formation, invasion and metastasis. | MIG7 is involved in vasculogenic mimicry formation rendering invasion and metastasis in hepatocellular carcinoma.
Qu B, Sheng G, Guo L, Yu F, Chen G, Lu Q, Wang R, Han B, Lu Y. | 01/20/2021 |
| this study indicates that the expression of Mig-7 in gliomas is positively correlated with vasculogenic mimicry formation and is related to the glioma pathological grade | Silencing of Mig-7 expression inhibits in-vitro invasiveness and vasculogenic mimicry of human glioma U87 Cells.
Pan Z, Zhu Q, You W, Shen C, Hu W, Chen X. | 01/20/2021 |
| MIG-7 serves as an independent unfavorable prognostic indicator in osteosarcoma patients and MIG-7 is an important mediator of osteosarcoma Vascular Mimicry formation. | Migration-inducing gene-7 independently predicts poor prognosis of human osteosarcoma and is associated with vasculogenic mimicry.
Ren K, Zhang J, Gu X, Wu S, Shi X, Ni Y, Chen Y, Lu J, Gao Z, Wang C, Yao N. | 01/20/2021 |
| The high expressions of Mig-7 and MMP-2 in gastric carcinoma tissues may have a synergistic promoting effect on VM formation. VM is closely associated with the invasion, metastasis and poor prognosis of gastric carcinoma. | [Expressions and clinical significance of vasculogenic mimicry and related protein Mig-7 and MMP-2 in gastric carcinoma].
Liao S, Gao Q. | 01/20/2021 |
| MIG7 expression in hepatocellular carcinoma tissue is high and correlated positively with vasculogenic mimicry formation, invasion and metastasis. | [MIG7 Regulates the Vasculogenic Mimicry Formation in Hepatocellular Carcinoma then Effects the Metastasis Potential of HCC].
Qu B, Yu F, Sheng GN, Chen GN, Lü Q, Gu YJ, Guo L. | 01/20/2021 |
| Silencing of Mig-7 gene inhibits vasculogenic mimicry formation and invasion of U251 cells possibly by suppressing MEK/ERK signaling, suggesting the important role of Mig-7 gene in vasculogenic mimicry formation and invasion of human glioma cells | [Mig-7 gene silencing inhibits vasculogenic mimicry formation and invasion of glioma U251 cells in vitro by suppressing MEK/ERK signaling].
Wang F, Chen F, Hu W, Zhang Y., Free PMC Article | 01/20/2021 |
| Inhibiting MIG-7 by RNA interference in grafted EOC cells retarded tumor growth, angiogenesis and improved host survival, and suppressing MIG-7 expression with a small molecule inhibitor D-39 identified from the mitigated EOC growth and invasion and specifically abrogated the expression of vascular endothelial growth factor. | Migration-inducing gene 7 promotes tumorigenesis and angiogenesis and independently predicts poor prognosis of epithelial ovarian cancer.
Huang B, Yin M, Li X, Cao G, Qi J, Lou G, Sheng S, Kou J, Chen K, Yu B., Free PMC Article | 01/20/2021 |
| miR-126-5p negatively regulated BCAR3 expression in eutopic endometriosis, enhanced the migration and invasion of endometrial cells, and promoted the occurrence of endometriosis. | MicroRNA-126-5p downregulates BCAR3 expression to promote cell migration and invasion in endometriosis.
Meng X, Liu J, Wang H, Chen P, Wang D. | 05/30/2020 |
| high expression level of BCAR3 predicted better prognosis of multiple myeloma patients. | Prediction and prognostic significance of BCAR3 expression in patients with multiple myeloma.
Zhang W, Lin Y, Liu X, He X, Zhang Y, Fu W, Yang Z, Yang P, Wang J, Hu K, Zhang X, Liu W, Yuan X, Jing H., Free PMC Article | 06/22/2019 |
| BCAR3 is an essential interactor and mediator of HEF1-induced migration. | Human enhancer of filamentation 1-induced colorectal cancer cell migration: Role of serine phosphorylation and interaction with the breast cancer anti-estrogen resistance 3 protein.
Ibrahim R, Lemoine A, Bertoglio J, Raingeaud J. | 03/12/2016 |
| BCAR3 acts as a putative suppressor of breast cancer progression by inhibiting the prometastatic TGFbeta/Smad signaling pathway in invasive breast tumors. | Breast cancer anti-estrogen resistance 3 inhibits transforming growth factor β/Smad signaling and associates with favorable breast cancer disease outcomes.
Guo J, Canaff L, Rajadurai CV, Fils-Aimé N, Tian J, Dai M, Korah J, Villatoro M, Park M, Ali S, Lebrun JJ., Free PMC Article | 11/14/2015 |
| BCAR1 and BCAR3 scaffolding proteins have roles in cell signaling and antiestrogen resistance | Association of the breast cancer antiestrogen resistance protein 1 (BCAR1) and BCAR3 scaffolding proteins in cell signaling and antiestrogen resistance.
Wallez Y, Riedl SJ, Pasquale EB., Free PMC Article | 06/21/2014 |
| Taken together, these results demonstrated that BCAR3 plays an important role in the signaling pathways of insulin leading to cell cycle progression and cytoskeleton reorganization, but not GLUT4 translocation. | Functional roles of BCAR3 in the signaling pathways of insulin leading to DNA synthesis, membrane ruffling and GLUT4 translocation.
Oh MJ, Yi SJ, Kim HS, Kim JH, Jeong YH, van Agthoven T, Jhun BH. | 04/5/2014 |
| BCAR3 promotes cell motility by regulating actin cytoskeletal and adhesion remodeling in invasive breast cancer cells. | Breast cancer antiestrogen resistance 3 (BCAR3) promotes cell motility by regulating actin cytoskeletal and adhesion remodeling in invasive breast cancer cells.
Wilson AL, Schrecengost RS, Guerrero MS, Thomas KS, Bouton AH., Free PMC Article | 01/18/2014 |
| BCAR3 expression may regulate Src signaling in a BCAR3-p130(cas) complex-dependent fashion by altering the ability of the Src SH3 domain to bind the p130(cas) SBD | Breast cancer anti-estrogen resistance 3 (BCAR3) protein augments binding of the c-Src SH3 domain to Crk-associated substrate (p130cas).
Makkinje A, Vanden Borre P, Near RI, Patel PS, Lerner A., Free PMC Article | 11/17/2012 |
| BCAR3-p130Cas complex formation is not required for BCAR3-mediated anti-estrogen resistance, Rac activation or discohesion of epithelial breast cancer cells | BCAR3/AND-34 can signal independent of complex formation with CAS family members or the presence of p130Cas.
Vanden Borre P, Near RI, Makkinje A, Mostoslavsky G, Lerner A., Free PMC Article | 04/10/2012 |
| Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator) | Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.
Bailey SD, Xie C, Do R, Montpetit A, Diaz R, Mohan V, Keavney B, Yusuf S, Gerstein HC, Engert JC, Anand S, DREAM investigators., Free PMC Article | 09/15/2010 |
| Observational study of gene-disease association. (HuGE Navigator) | Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.
Talmud PJ, Drenos F, Shah S, Shah T, Palmen J, Verzilli C, Gaunt TR, Pallas J, Lovering R, Li K, Casas JP, Sofat R, Kumari M, Rodriguez S, Johnson T, Newhouse SJ, Dominiczak A, Samani NJ, Caulfield M, Sever P, Stanton A, Shields DC, Padmanabhan S, Melander O, Hastie C, Delles C, Ebrahim S, Marmot MG, Smith GD, Lawlor DA, Munroe PB, Day IN, Kivimaki M, Whittaker J, Humphries SE, Hingorani AD, ASCOT investigators, NORDIL investigators, BRIGHT Consortium., Free PMC Article | 09/15/2010 |
| the c-Src/Cas/BCAR3 signaling axis is a prominent regulator of c-Src activity, which in turn controls cell behaviors that lead to aggressive and invasive breast tumor phenotypes | BCAR3 regulates Src/p130 Cas association, Src kinase activity, and breast cancer adhesion signaling.
Schuh NR, Guerrero MS, Schrecengost RS, Bouton AH., Free PMC Article | 03/1/2010 |
| The expression of breast cancer anti-estrogen resistance 3 results in basal serine phosphorylation of Crk-Associated Substrate Protein that normally occurs during adhesion of breast cancer cells to fibronectin. | AND-34/BCAR3 regulates adhesion-dependent p130Cas serine phosphorylation and breast cancer cell growth pattern.
Makkinje A, Near RI, Infusini G, Vanden Borre P, Bloom A, Cai D, Costello CE, Lerner A., Free PMC Article | 01/21/2010 |
| BCAR3 protein, through its SH2 domain, is involved in the signaling pathways of EGF leading to cell cycle progression; BCAR3 itself is part of a mitogenic signaling pathway. | BCAR3 regulates EGF-induced DNA synthesis in normal human breast MCF-12A cells.
Oh MJ, van Agthoven T, Choi JE, Jeong YJ, Chung YH, Kim CM, Jhun BH. | 01/21/2010 |