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    HTR12 Histone superfamily protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 839104, updated on 18-Sep-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Heat stress promotes haploid formation during CENH3-mediated genome elimination in Arabidopsis.

    Heat stress promotes haploid formation during CENH3-mediated genome elimination in Arabidopsis.
    Jin C, Sun L, Trinh HK, Danny G.

    06/14/2023
    Extreme divergence in CENH3 protein sequence does not alter centromere location in Arabidopsis.

    Centromere location in Arabidopsis is unaltered by extreme divergence in CENH3 protein sequence.
    Maheshwari S, Ishii T, Brown CT, Houben A, Comai L., Free PMC Article

    01/13/2018
    Arabidopsis KNL2 colocalizes with cenH3 and is associated with centromeres during all stages of the mitotic cell cycle, except from metaphase to mid-anaphase.

    Arabidopsis kinetochore null2 is an upstream component for centromeric histone H3 variant cenH3 deposition at centromeres.
    Lermontova I, Kuhlmann M, Friedel S, Rutten T, Heckmann S, Sandmann M, Demidov D, Schubert V, Schubert I., Free PMC Article

    05/16/2015
    Reduced endogenous CENH3 and lack of meiotic incorporation of EYFP-CENH3(C) lead to reduced fertility caused by insufficient CENH3 loading to the centromeres of meiotic chromosomes, subsequent lagging of chromosomes and formation of micronuclei.

    Knockdown of CENH3 in Arabidopsis reduces mitotic divisions and causes sterility by disturbed meiotic chromosome segregation.
    Lermontova I, Koroleva O, Rutten T, Fuchs J, Schubert V, Moraes I, Koszegi D, Schubert I.

    06/8/2013
    Silencing of the AtTERT gene is associated with increased H3K27me3 loading and maintenance of its euchromatic environment.

    Developmental silencing of the AtTERT gene is associated with increased H3K27me3 loading and maintenance of its euchromatic environment.
    Ogrocká A, Sýkorová E, Fajkus J, Fojtová M., Free PMC Article

    11/24/2012
    CENH3 is expressed in dividing tissues and is CENH3 is transcriptionally regulated by E2F/DP transcription factors.

    The E2F transcription factor family regulates CENH3 expression in Arabidopsis thaliana.
    Heckmann S, Lermontova I, Berckmans B, De Veylder L, Bäumlein H, Schubert I.

    04/28/2012
    Deposition of Arabidopsis CENH3 takes place at centromeres during G2.

    Deposition, turnover, and release of CENH3 at Arabidopsis centromeres.
    Lermontova I, Rutten T, Schubert I.

    03/10/2012
    Meiosis-specific loading of the centromere-specific histone CENH3 in Arabidopsis thaliana

    Meiosis-specific loading of the centromere-specific histone CENH3 in Arabidopsis thaliana.
    Ravi M, Shibata F, Ramahi JS, Nagaki K, Chen C, Murata M, Chan SW., Free PMC Article

    11/5/2011
    study concludes that CENH3 function in A. thaliana, an organism with large tandem repeat centromeres, has stringent requirements for functional complementation in mitosis

    The rapidly evolving centromere-specific histone has stringent functional requirements in Arabidopsis thaliana.
    Ravi M, Kwong PN, Menorca RM, Valencia JT, Ramahi JS, Stewart JL, Tran RK, Sundaresan V, Comai L, Chan SW., Free PMC Article

    03/26/2011
    Alignment of CENH3 sequences revealed that the tested species share only three amino acids at loop1 region: threonine2, arginine12 and alanine15

    Recognition of A. thaliana centromeres by heterologous CENH3 requires high similarity to the endogenous protein.
    Moraes IC, Lermontova I, Schubert I.

    03/5/2011
    cenh3 null mutants expressing altered CENH3 proteins are crossed to wild type, chromosomes from the mutant are eliminated, producing haploid progeny

    Haploid plants produced by centromere-mediated genome elimination.
    Ravi M, Chan SW.

    04/12/2010
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