| Repression by the Arabidopsis TOPLESS corepressor requires association with the core mediator complex. | Repression by the Arabidopsis TOPLESS corepressor requires association with the core mediator complex.
Leydon AR, Wang W, Gala HP, Gilmour S, Juarez-Solis S, Zahler ML, Zemke JE, Zheng N, Nemhauser JL., Free PMC Article | 10/23/2021 |
| These results suggested that integrating activation of Brassinosteroid (BR)-signaling pathways with the formation of the protein complex containing BES1/BZR1 and TPL-HDA19 via the EAR motif was important in fine-tuning BR-related gene networks in plants. | Transcriptional network regulation of the brassinosteroid signaling pathway by the BES1-TPL-HDA19 co-repressor complex.
Kim H, Shim D, Moon S, Lee J, Bae W, Choi H, Kim K, Ryu H. | 12/14/2019 |
| the 1st WD40 propeller of TPL can form a complex with RAV1 both in yeast and in Arabidopsis protoplasts. | The C-terminal WD40 repeats on the TOPLESS co-repressor function as a protein-protein interaction surface.
Collins J, O'Grady K, Chen S, Gurley W. | 06/1/2019 |
| relative to mammalian TBL1, evolved a new tetramerization interface and unique and highly conserved surface for interaction with repressors | Structure of the Arabidopsis TOPLESS corepressor provides insight into the evolution of transcriptional repression.
Martin-Arevalillo R, Nanao MH, Larrieu A, Vinos-Poyo T, Mast D, Galvan-Ampudia C, Brunoud G, Vernoux T, Dumas R, Parcy F., Free PMC Article | 06/9/2018 |
| The GIR1 and GIR2 might may link TPL to and participate in epigenetic regulation of root hair development. | Adaptor proteins GIR1 and GIR2. II. Interaction with the co-repressor TOPLESS and promotion of histone deacetylation of target chromatin.
Wu R, Citovsky V., Free PMC Article | 10/7/2017 |
| These data unveil a pivotal role of the co-repressor TPL in the shoot and root meristems. | TOPLESS mediates brassinosteroid control of shoot boundaries and root meristem development in Arabidopsis thaliana.
Espinosa-Ruiz A, Martínez C, de Lucas M, Fàbregas N, Bosch N, Caño-Delgado AI, Prat S. | 09/16/2017 |
| Interaction of CO with miP1a/b/TPL causes late flowering due to a failure in the induction of FLOWERING LOCUS T (FT) expression under inductive long day conditions. | MicroProtein-Mediated Recruitment of CONSTANS into a TOPLESS Trimeric Complex Represses Flowering in Arabidopsis.
Graeff M, Straub D, Eguen T, Dolde U, Rodrigues V, Brandt R, Wenkel S., Free PMC Article | 08/6/2016 |
| Data showed that SPOROCYTELESS (SPL) most likely functions as a transcription repressor by interacting with TCP family transcription factors and the TOPLESS (TPL) co-repressors. | SPOROCYTELESS is a novel embryophyte-specific transcription repressor that interacts with TPL and TCP proteins in Arabidopsis.
Chen GH, Sun JY, Liu M, Liu J, Yang WC. | 08/29/2015 |
| TOPLESS mediates brassinosteroid-induced transcriptional repression through interaction with BZR1. | TOPLESS mediates brassinosteroid-induced transcriptional repression through interaction with BZR1.
Oh E, Zhu JY, Ryu H, Hwang I, Wang ZY., Free PMC Article | 07/25/2015 |
| Topless and Topless-related proteins form a tertiary complex with TIE1 protein at early stages of leaf development. | The TIE1 transcriptional repressor links TCP transcription factors with TOPLESS/TOPLESS-RELATED corepressors and modulates leaf development in Arabidopsis.
Tao Q, Guo D, Wei B, Zhang F, Pang C, Jiang H, Zhang J, Wei T, Gu H, Qu LJ, Qin G., Free PMC Article | 01/18/2014 |
| findings show that AP2 represses its target genes by physically recruiting the co-repressor TOPLESS and the histone deacetylase HDA19 | APETALA2 negatively regulates multiple floral organ identity genes in Arabidopsis by recruiting the co-repressor TOPLESS and the histone deacetylase HDA19.
Krogan NT, Hogan K, Long JA., Free PMC Article | 01/26/2013 |
| We identified transcription factors interacting with TPL. | The TOPLESS interactome: a framework for gene repression in Arabidopsis.
Causier B, Ashworth M, Guo W, Davies B., Free PMC Article | 07/14/2012 |
| Both NINJA and TPL were shown to function as negative regulators of jasmonate signaling. | Dissection of the one-MegaDalton JAZ1 protein complex.
Geerinck J, Pauwels L, De Jaeger G, Goossens A., Free PMC Article | 10/22/2011 |
| Arabidopsis JAZ proteins recruit the Groucho/Tup1-type co-repressor TOPLESS (TPL) and TPL-related proteins (TPRs) through a previously uncharacterized adaptor protein, designated Novel Interactor of JAZ (NINJA) | NINJA connects the co-repressor TOPLESS to jasmonate signalling.
Pauwels L, Barbero GF, Geerinck J, Tilleman S, Grunewald W, Pérez AC, Chico JM, Bossche RV, Sewell J, Gil E, García-Casado G, Witters E, Inzé D, Long JA, De Jaeger G, Solano R, Goossens A., Free PMC Article | 05/31/2010 |
| TPL can interact with IAA12/BODENLOS through an ETHYLENE RESPONSE FACTOR-associated amphiphilic repression motif; study shows TPL is a transcriptional co-repressor & furthers understanding of how auxin regulates transcription during plant development | TOPLESS mediates auxin-dependent transcriptional repression during Arabidopsis embryogenesis.
Szemenyei H, Hannon M, Long JA. | 01/21/2010 |
| TPL and other TPR proteins are necessary to repress the expression of root-promoting genes in the top half of the embryo to allow proper differentiation of the shoot pole. [topless][TPL] | TOPLESS regulates apical embryonic fate in Arabidopsis.
Long JA, Ohno C, Smith ZR, Meyerowitz EM. | 01/21/2010 |