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    dmd dystrophin [ Danio rerio (zebrafish) ]

    Gene ID: 83773, updated on 9-Dec-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Effect of serotonin modulation on dystrophin-deficient zebrafish.

    Effect of serotonin modulation on dystrophin-deficient zebrafish.
    Spinazzola JM, Lambert MR, Gibbs DE, Conner JR, Krikorian GL, Pareek P, Rago C, Kunkel LM., Free PMC Article

    09/18/2021
    Forced expression of embryonic dystrophin in zebrafish using an exon-skipping approach severely impairs the mobility and muscle architecture.

    Abnormal splicing switch of DMD's penultimate exon compromises muscle fibre maintenance in myotonic dystrophy.
    Rau F, Lainé J, Ramanoudjame L, Ferry A, Arandel L, Delalande O, Jollet A, Dingli F, Lee KY, Peccate C, Lorain S, Kabashi E, Athanasopoulos T, Koo T, Loew D, Swanson MS, Le Rumeur E, Dickson G, Allamand V, Marie J, Furling D., Free PMC Article

    04/9/2016
    Spatio-temporal differences in dystrophin dynamics at mRNA and protein levels have been revealed using a novel reporter system.

    Spatio-Temporal Differences in Dystrophin Dynamics at mRNA and Protein Levels Revealed by a Novel FlipTrap Line.
    Ruf-Zamojski F, Trivedi V, Fraser SE, Trinh le A., Free PMC Article

    03/19/2016
    Data indicate that ataluren (0.1-1 muM, 3-5 dpf) improved contractile function (~60% improvement of force at 0.5 muM) and dystrophin expression.

    Muscle dysfunction and structural defects of dystrophin-null sapje mutant zebrafish larvae are rescued by ataluren treatment.
    Li M, Andersson-Lendahl M, Sejersen T, Arner A.

    06/7/2014
    Ordered disorder of the astrocytic dystrophin-associated protein complex in the norm and pathology.

    Ordered disorder of the astrocytic dystrophin-associated protein complex in the norm and pathology.
    Na I, Redmon D, Kopa M, Qin Y, Xue B, Uversky VN., Free PMC Article

    04/5/2014
    early expression of the short carboxyl-terminal dystrophin transcript, with expression of the full length muscle transcript occurring during myogenesis.

    Zebrafish dystrophin and utrophin genes: dissecting transcriptional expression during embryonic development.
    Lai D, Lan CC, Leong IU, Love DR.

    07/21/2012
    Data suggest that dystrophin functions in regulation of calcium signaling during early stages of slow muscle cell differentiation; calcium signaling in these cells coincide with first spontaneous contractions of embryonic trunk.

    Application of complementary luminescent and fluorescent imaging techniques to visualize nuclear and cytoplasmic Ca²⁺ signalling during the in vivo differentiation of slow muscle cells in zebrafish embryos under normal and dystrophic conditions.
    Webb SE, Cheung CC, Chan CM, Love DR, Miller AL.

    05/5/2012
    Sequence analysis of sapje-like genomic DNA identified a mutation in the donor splice junction at the end of dystrophin exon 62.

    Genetic isolation and characterization of a splicing mutant of zebrafish dystrophin.
    Guyon JR, Goswami J, Jun SJ, Thorne M, Howell M, Pusack T, Kawahara G, Steffen LS, Galdzicki M, Kunkel LM., Free PMC Article

    01/21/2010
    reduction of dystrophin, dystroglycan and sarcoglycan at translational level in embryos with overexpressed myostatin2

    Overexpression of Myostatin2 in zebrafish reduces the expression of dystrophin associated protein complex (DAPC) which leads to muscle dystrophy.
    Amali AA, Lin CJ, Chen YH, Wang WL, Gong HY, Rekha RD, Lu JK, Chen TT, Wu JL.

    01/21/2010
    Dystrophin family gene expression in zebrafish is reported.

    Dystrobrevin and dystrophin family gene expression in zebrafish.
    Böhm S, Jin H, Hughes SM, Roberts RG, Hinits Y., Free PMC Article

    01/21/2010
    Data suggest that the progressive muscle degeneration phenotype of dystrophin mutant zebrafish embryos is caused by the failure of embryonic muscle end attachments.

    Dystrophin is required for the formation of stable muscle attachments in the zebrafish embryo.
    Bassett DI, Bryson-Richardson RJ, Daggett DF, Gautier P, Keenan DG, Currie PD.

    01/21/2010
    analysis of the dystrophin associated protein complex in zebrafish

    The dystrophin associated protein complex in zebrafish.
    Guyon JR, Mosley AN, Zhou Y, O'Brien KF, Sheng X, Chiang K, Davidson AJ, Volinski JM, Zon LI, Kunkel LM.

    01/21/2010
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