Effect of serotonin modulation on dystrophin-deficient zebrafish. | Effect of serotonin modulation on dystrophin-deficient zebrafish. Spinazzola JM, Lambert MR, Gibbs DE, Conner JR, Krikorian GL, Pareek P, Rago C, Kunkel LM., Free PMC Article | 09/18/2021 |
Forced expression of embryonic dystrophin in zebrafish using an exon-skipping approach severely impairs the mobility and muscle architecture. | Abnormal splicing switch of DMD's penultimate exon compromises muscle fibre maintenance in myotonic dystrophy. Rau F, Lainé J, Ramanoudjame L, Ferry A, Arandel L, Delalande O, Jollet A, Dingli F, Lee KY, Peccate C, Lorain S, Kabashi E, Athanasopoulos T, Koo T, Loew D, Swanson MS, Le Rumeur E, Dickson G, Allamand V, Marie J, Furling D., Free PMC Article | 04/9/2016 |
Spatio-temporal differences in dystrophin dynamics at mRNA and protein levels have been revealed using a novel reporter system. | Spatio-Temporal Differences in Dystrophin Dynamics at mRNA and Protein Levels Revealed by a Novel FlipTrap Line. Ruf-Zamojski F, Trivedi V, Fraser SE, Trinh le A., Free PMC Article | 03/19/2016 |
Data indicate that ataluren (0.1-1 muM, 3-5 dpf) improved contractile function (~60% improvement of force at 0.5 muM) and dystrophin expression. | Muscle dysfunction and structural defects of dystrophin-null sapje mutant zebrafish larvae are rescued by ataluren treatment. Li M, Andersson-Lendahl M, Sejersen T, Arner A. | 06/7/2014 |
Ordered disorder of the astrocytic dystrophin-associated protein complex in the norm and pathology. | Ordered disorder of the astrocytic dystrophin-associated protein complex in the norm and pathology. Na I, Redmon D, Kopa M, Qin Y, Xue B, Uversky VN., Free PMC Article | 04/5/2014 |
early expression of the short carboxyl-terminal dystrophin transcript, with expression of the full length muscle transcript occurring during myogenesis. | Zebrafish dystrophin and utrophin genes: dissecting transcriptional expression during embryonic development. Lai D, Lan CC, Leong IU, Love DR. | 07/21/2012 |
Data suggest that dystrophin functions in regulation of calcium signaling during early stages of slow muscle cell differentiation; calcium signaling in these cells coincide with first spontaneous contractions of embryonic trunk. | Application of complementary luminescent and fluorescent imaging techniques to visualize nuclear and cytoplasmic Ca²⁺ signalling during the in vivo differentiation of slow muscle cells in zebrafish embryos under normal and dystrophic conditions. Webb SE, Cheung CC, Chan CM, Love DR, Miller AL. | 05/5/2012 |
Sequence analysis of sapje-like genomic DNA identified a mutation in the donor splice junction at the end of dystrophin exon 62. | Genetic isolation and characterization of a splicing mutant of zebrafish dystrophin. Guyon JR, Goswami J, Jun SJ, Thorne M, Howell M, Pusack T, Kawahara G, Steffen LS, Galdzicki M, Kunkel LM., Free PMC Article | 01/21/2010 |
reduction of dystrophin, dystroglycan and sarcoglycan at translational level in embryos with overexpressed myostatin2 | Overexpression of Myostatin2 in zebrafish reduces the expression of dystrophin associated protein complex (DAPC) which leads to muscle dystrophy. Amali AA, Lin CJ, Chen YH, Wang WL, Gong HY, Rekha RD, Lu JK, Chen TT, Wu JL. | 01/21/2010 |
Dystrophin family gene expression in zebrafish is reported. | Dystrobrevin and dystrophin family gene expression in zebrafish. Böhm S, Jin H, Hughes SM, Roberts RG, Hinits Y., Free PMC Article | 01/21/2010 |
Data suggest that the progressive muscle degeneration phenotype of dystrophin mutant zebrafish embryos is caused by the failure of embryonic muscle end attachments. | Dystrophin is required for the formation of stable muscle attachments in the zebrafish embryo. Bassett DI, Bryson-Richardson RJ, Daggett DF, Gautier P, Keenan DG, Currie PD. | 01/21/2010 |
analysis of the dystrophin associated protein complex in zebrafish | The dystrophin associated protein complex in zebrafish. Guyon JR, Mosley AN, Zhou Y, O'Brien KF, Sheng X, Chiang K, Davidson AJ, Volinski JM, Zon LI, Kunkel LM. | 01/21/2010 |