| RPS4 domains responsible for response to bacterial effectors from plant pathogens. | Distinct modes of derepression of an Arabidopsis immune receptor complex by two different bacterial effectors.
Ma Y, Guo H, Hu L, Martinez PP, Moschou PN, Cevik V, Ding P, Duxbury Z, Sarris PF, Jones JDG., Free PMC Article | 11/17/2018 |
| Although quantitative disease resistance (QDR) to Xanthomonas campestris is conferred by At5g22540 encoding for a protein of unknown function, QDR to XccCFBP6943 involves the well-known immune receptor pair RRS1/RPS4. | Quantitative disease resistance to the bacterial pathogen Xanthomonas campestris involves an Arabidopsis immune receptor pair and a gene of unknown function.
Debieu M, Huard-Chauveau C, Genissel A, Roux F, Roby D., Free PMC Article | 01/14/2017 |
| The RRS1-leucine zipper motif is crucial for the regulation of the RPS4/RRS1 complex. | Leucine zipper motif in RRS1 is crucial for the regulation of Arabidopsis dual resistance protein complex RPS4/RRS1.
Narusaka M, Toyoda K, Shiraishi T, Iuchi S, Takano Y, Shirasu K, Narusaka Y., Free PMC Article | 12/17/2016 |
| Here, we report that dual R proteins, RRS1 and RPS4, from A. thaliana ecotype Wassilewskija confer resistance to bacterial wilt in transgenic Brassica crops. | Arabidopsis dual resistance proteins, both RPS4 and RRS1, are required for resistance to bacterial wilt in transgenic Brassica crops.
Narusaka M, Hatakeyama K, Shirasu K, Narusaka Y., Free PMC Article | 11/7/2015 |
| The Arabidopsis RRS1-R nucleotide-binding, leucine-rich repeat (NB-LRR) protein carries a C-terminal WRKY DNA binding domain and forms a receptor complex with RPS4, another NB-LRR protein. This complex detects the bacterial effectors AvrRps4 or PopP2 and then activates defense. | A Plant Immune Receptor Detects Pathogen Effectors that Target WRKY Transcription Factors.
Sarris PF, Duxbury Z, Huh SU, Ma Y, Segonzac C, Sklenar J, Derbyshire P, Cevik V, Rallapalli G, Saucet SB, Wirthmueller L, Menke FLH, Sohn KH, Jones JDG. | 08/1/2015 |
| We show that many sushi(slh1) mutants carry mutations in RPS4, suggesting that RPS4 acts downstream or in a complex with RRS1. Interestingly, several mutations were identified in a domain C-terminal to the RPS4 LRR domain | The nuclear immune receptor RPS4 is required for RRS1SLH1-dependent constitutive defense activation in Arabidopsis thaliana.
Sohn KH, Segonzac C, Rallapalli G, Sarris PF, Woo JY, Williams SJ, Newman TE, Paek KH, Kobe B, Jones JD., Free PMC Article | 07/4/2015 |
| findings show RPS4 and RRS1 physically associate; TIR domain heterodimerization is required to form a functional RRS1/RPS4 effector recognition complex; RPS4 and RRS1 function as a receptor complex in which the 2 components play distinct roles in recognition and signaling | Structural basis for assembly and function of a heterodimeric plant immune receptor.
Williams SJ, Sohn KH, Wan L, Bernoux M, Sarris PF, Segonzac C, Ve T, Ma Y, Saucet SB, Ericsson DJ, Casey LW, Lonhienne T, Winzor DJ, Zhang X, Coerdt A, Parker JE, Dodds PN, Kobe B, Jones JD. | 05/3/2014 |
| A pair of Arabidopsis nucleotide binding and leucine rich repeat-type R genes, RPS4 and RRS1, properly function in two other Brassicaceae, Brassica rapa and Brassica napus, but also in two Solanaceae, Nicotiana benthamiana and tomato. | Interfamily transfer of dual NB-LRR genes confers resistance to multiple pathogens.
Narusaka M, Kubo Y, Hatakeyama K, Imamura J, Ezura H, Nanasato Y, Tabei Y, Takano Y, Shirasu K, Narusaka Y., Free PMC Article | 08/31/2013 |
| Abscisic acid deficiency promotes the activity and nuclear localization of RPS4 at higher temperatures. | Abscisic acid deficiency antagonizes high-temperature inhibition of disease resistance through enhancing nuclear accumulation of resistance proteins SNC1 and RPS4 in Arabidopsis.
Mang HG, Qian W, Zhu Y, Qian J, Kang HG, Klessig DF, Hua J., Free PMC Article | 10/6/2012 |
| study shows EDS1 forms complexes with the TIR-NB-LRR resistance proteins RPS4 and RPS6 and the negative immune regulator SRFR1 at a cytoplasmic membrane | Pathogen effectors target Arabidopsis EDS1 and alter its interactions with immune regulators.
Bhattacharjee S, Halane MK, Kim SH, Gassmann W. | 01/28/2012 |
| EDS1 molecularly connects TIR-NB-LRR disease resistance protein RPS4 recognition of bacterial effector AvrRps4 to defense pathways; EDS1 behaves as an effector target and activated TIR-NB-LRR signal transducer for defense across cell compartments | Arabidopsis EDS1 connects pathogen effector recognition to cell compartment-specific immune responses.
Heidrich K, Wirthmueller L, Tasset C, Pouzet C, Deslandes L, Parker JE. | 01/28/2012 |
| Distinct allelic forms of RPS4 and RRS1 probably cooperate to confer resistance to different pathogens. | A locus conferring resistance to Colletotrichum higginsianum is shared by four geographically distinct Arabidopsis accessions.
Birker D, Heidrich K, Takahara H, Narusaka M, Deslandes L, Narusaka Y, Reymond M, Parker JE, O'Connell R. | 01/21/2010 |
| RRS1-Ws and RPS4-Ws, function cooperatively as a dual R-gene system against at least three distinct pathogens. | RRS1 and RPS4 provide a dual Resistance-gene system against fungal and bacterial pathogens.
Narusaka M, Shirasu K, Noutoshi Y, Kubo Y, Shiraishi T, Iwabuchi M, Narusaka Y. | 01/21/2010 |
| RPS4 function is regulated at multiple levels, including gene expression, alternative splicing, and protein stability, presumably to fine-tune activity and limit damage inflicted by activated RPS4 protein. | Alternative splicing and mRNA levels of the disease resistance gene RPS4 are induced during defense responses.
Zhang XC, Gassmann W., Free PMC Article | 01/21/2010 |