ABD1 interacts with DDB1 in vitro and in vivo, indicating that it likely functions as a CUL4 E3 ligase substrate receptor. | ABD1 is an Arabidopsis DCAF substrate receptor for CUL4-DDB1-based E3 ligases that acts as a negative regulator of abscisic acid signaling. Seo KI, Lee JH, Nezames CD, Zhong S, Song E, Byun MO, Deng XW., Free PMC Article | 11/22/2014 |
that a DDB1(WDR55) complex could regulate embryo and endosperm development. | The Arabidopsis DDB1 interacting protein WDR55 is required for vegetative development. Bjerkan KN, Grini PE., Free PMC Article | 06/21/2014 |
UVH6, DDB1A, and DDB2 all contribute to UV tolerance, heat tolerance and floral patterning. | Interactions between Arabidopsis DNA repair genes UVH6, DDB1A, and DDB2 during abiotic stress tolerance and floral development. Ly V, Hatherell A, Kim E, Chan A, Belmonte MF, Schroeder DF. | 05/17/2014 |
DDB1A and DDB1B contribute to DET1 regulation of adult plant growth. | Genetic interactions of Arabidopsis thaliana damaged DNA binding protein 1B (DDB1B) with DDB1A, DET1, and COP1. Ganpudi AL, Schroeder DF., Free PMC Article | 09/28/2013 |
DDB1a is an novel RUB-modified protein. | Recovery of DDB1a (damaged DNA binding protein1a) in a screen to identify novel RUB-modified proteins in Arabidopsis thaliana. Hotton SK, Castro MF, Eigenheer RA, Callis J. | 02/2/2013 |
WDR55-DDB1 complex is involved in the establishment of bilateral symmetry in the Arabidopsis embryo. | Arabidopsis WD repeat domain55 Interacts with DNA damaged binding protein1 and is required for apical patterning in the embryo. Bjerkan KN, Jung-Roméo S, Jürgens G, Genschik P, Grini PE., Free PMC Article | 10/6/2012 |
CUL4-DDB1 complex interacts with MSI1 and is required to maintain MEDEA parental imprinting. | The Arabidopsis CUL4-DDB1 complex interacts with MSI1 and is required to maintain MEDEA parental imprinting. Dumbliauskas E, Lechner E, Jaciubek M, Berr A, Pazhouhandeh M, Alioua M, Cognat V, Brukhin V, Koncz C, Grossniklaus U, Molinier J, Genschik P., Free PMC Article | 05/14/2011 |
data suggest that the plant CUL4-DDB1A(CSAat1A and B) complex represents a unique mechanism to promote ubiquitination of substrates in response to DNA damage | Arabidopsis cockayne syndrome A-like proteins 1A and 1B form a complex with CULLIN4 and damage DNA binding protein 1A and regulate the response to UV irradiation. Zhang C, Guo H, Zhang J, Guo G, Schumaker KS, Guo Y., Free PMC Article | 01/1/2011 |
demonstrated that DDB1a, like DDB1b, is critical for embryo development, and that both proteins have distinct functions in whole plant development | Arabidopsis DDB1a and DDB1b are critical for embryo development. Bernhardt A, Mooney S, Hellmann H. | 12/4/2010 |
CUL4-DDB1 and COP1-SPA complexes act together to regulate photomorphogenesis. | Arabidopsis CULLIN4-damaged DNA binding protein 1 interacts with CONSTITUTIVELY PHOTOMORPHOGENIC1-SUPPRESSOR OF PHYA complexes to regulate photomorphogenesis and flowering time. Chen H, Huang X, Gusmaroli G, Terzaghi W, Lau OS, Yanagawa Y, Zhang Y, Li J, Lee JH, Zhu D, Deng XW., Free PMC Article | 04/19/2010 |
DDB1A-3HA overexpression affected phenotypes in a variety of DET1 backgrounds, reduced epitope-tagged DET1 levels, and, correlatively, in general dampened the rescue of det1 mutants by the DET1-DDB1A complex. | Effect of overexpression of Arabidopsis damaged DNA-binding protein 1A on de-etiolated 1. Zhang Y, Schroeder DF. | 04/12/2010 |
Results show that DDB1A is required for UV regulation of DDB1B and DDB2 mRNA levels while DDB1A is sufficient to increase Arabidopsis UV tolerance. | Overexpression of Arabidopsis damaged DNA binding protein 1A (DDB1A) enhances UV tolerance. Al Khateeb WM, Schroeder DF. | 01/21/2010 |
CUL4-DDB1A-DDB2 complex is involved in global genome repair of UV-induced DNA lesions. | Regulation and role of Arabidopsis CUL4-DDB1A-DDB2 in maintaining genome integrity upon UV stress. Molinier J, Lechner E, Dumbliauskas E, Genschik P., Free PMC Article | 01/21/2010 |
DDB1A-dependent phenotypes indicate a competition between DDB2- and DET1-containing complexes for available DDB1A, while, for DDB1A-independent phenotypes, DDB1B is able to fulfill this role. | DDB2, DDB1A and DET1 exhibit complex interactions during Arabidopsis development. Al Khateeb WM, Schroeder DF., Free PMC Article | 01/21/2010 |
Arabidopsis cullin 4 is shown to assemble with DDB1, RBX1, DET1 and DDB2 in vitro and in planta.[DDB1A] | CUL4 associates with DDB1 and DET1 and its downregulation affects diverse aspects of development in Arabidopsis thaliana. Bernhardt A, Lechner E, Hano P, Schade V, Dieterle M, Anders M, Dubin MJ, Benvenuto G, Bowler C, Genschik P, Hellmann H. | 01/21/2010 |