| Syntaxin-4 and CRACM3 interact in a non-excitable vesicle fusion.Extracellular loop 3 and the C-terminus of CRACM3 are critical for binding the N-peptide of syntaxin-4. | CRACM3 regulates the stability of non-excitable exocytotic vesicle fusion pores in a Ca(2+)-independent manner via molecular interaction with syntaxin4.
Liu S, Sahid MN, Takemasa E, Kiyoi T, Kuno M, Oshima Y, Maeyama K., Free PMC Article | 08/18/2018 |
| Syntaxin-4 and SNAP23 act as exocytic soluble N-ethylmaleimide-sensitive factor attachment protein receptors (SNAREs) to release nerve growth factors from cultured Schwann cells. | Syntaxin-4 and SNAP23 act as exocytic SNAREs to release NGF from cultured Schwann cells.
Lin M, Jiang M, Ding F, Cao Z. | 05/5/2018 |
| Our study uncovers the postsynaptic function of the SNAP25-VAMP1-syntaxin4 complex in mediating the constitutive exocytosis of NMDA receptors, suggesting that this SNARE complex is involved in excitatory synaptic transmission | Identification of the SNARE complex mediating the exocytosis of NMDA receptors.
Gu Y, Huganir RL., Free PMC Article | 02/10/2018 |
| Syntaxin 1 was localized to the plasma membrane of the presynaptic terminal, including the active zone, while syntaxin 4 was localized to peri-synaptic astroglial processes. Results show that syntaxin 4 is available to support exocytosis in astroglia. | Syntaxin 4 is concentrated on plasma membrane of astrocytes.
Tao-Cheng JH, Pham A, Yang Y, Winters CA, Gallant PE, Reese TS., Free PMC Article | 09/26/2015 |
| Transcriptional expression of myelin basic protein in oligodendrocytes depends on functional syntaxin 4. | Transcriptional expression of myelin basic protein in oligodendrocytes depends on functional syntaxin 4: a potential correlation with autocrine signaling.
Bijlard M, Klunder B, de Jonge JC, Nomden A, Tyagi S, de Vries H, Hoekstra D, Baron W., Free PMC Article | 04/18/2015 |
| These data suggest that Rab17 mediates the dendritic trafficking of Syntaxin-4 to selectively regulate dendritic surface insertion of GluK2-containing KARs in rat hippocampal neurons. | Small GTPase Rab17 regulates the surface expression of kainate receptors but not α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors in hippocampal neurons via dendritic trafficking of Syntaxin-4 protein.
Mori Y, Fukuda M, Henley JM., Free PMC Article | 02/14/2015 |
| regulation of mucosal mast cell activation | Regulation of mucosal mast cell activation by short interfering RNAs targeting syntaxin4.
Liu S, Nugroho AE, Shudou M, Maeyama K. | 08/18/2012 |
| Data showv that complexin 2 interacts with vesicle-associated membrane protein (VAMP) 2, syntaxins 3 and 4. | Complexin 2 modulates vesicle-associated membrane protein (VAMP) 2-regulated zymogen granule exocytosis in pancreatic acini.
Falkowski MA, Thomas DD, Groblewski GE., Free PMC Article | 02/26/2011 |
| Syntaxin-4 and VAMP-1 and VAMP-2 regulate cardiac myocyte exocytosis of ANP. | VAMP-1, VAMP-2, and syntaxin-4 regulate ANP release from cardiac myocytes.
Ferlito M, Fulton WB, Zauher MA, Marbán E, Steenbergen C, Lowenstein CJ., Free PMC Article | 01/22/2011 |
| Report interactions between syntaxin 4 and aquaporins in inner medullary collecting ducts. | Syntaxin specificity of aquaporins in the inner medullary collecting duct.
Mistry AC, Mallick R, Klein JD, Weimbs T, Sands JM, Fröhlich O., Free PMC Article | 01/21/2010 |
| Sensitization with OVA increases the expression in mast cells | Allergen-sensitization increases mast-cell expression of the exocytotic proteins SNAP-23 and syntaxin 4, which are involved in histamine secretion.
Salinas E, Quintanar-Stephano A, Córdova LE, Ouintanar JL. | 01/21/2010 |
| expression and localization of plasma membrane syntaxins which may contribute to the trafficking phenotype of retinal pigment epithelial cells | Retinal pigment epithelial cells exhibit unique expression and localization of plasma membrane syntaxins which may contribute to their trafficking phenotype.
Low SH, Marmorstein LY, Miura M, Li X, Kudo N, Marmorstein AD, Weimbs T. | 01/21/2010 |
| Together, our data suggest that insulin induces remodeling of the fodrin-actin network, which is required for the fusion of GLUT4 storage vesicles with the plasma membrane by permitting their access to the t-SNARE syntaxin 4. | Role of insulin-dependent cortical fodrin/spectrin remodeling in glucose transporter 4 translocation in rat adipocytes.
Liu L, Jedrychowski MP, Gygi SP, Pilch PF., Free PMC Article | 01/21/2010 |
| Data show that Munc18c binds to monomeric syntaxin4 and the N-terminal 29 amino acids of syntaxin4 are necessary for this interaction. | Molecular dissection of the Munc18c/syntaxin4 interaction: implications for regulation of membrane trafficking.
Latham CF, Lopez JA, Hu SH, Gee CL, Westbury E, Blair DH, Armishaw CJ, Alewood PF, Bryant NJ, James DE, Martin JL. | 01/21/2010 |