| LncRNA GAS5 modulates Schwann cell function and enhances facial nerve injury repair via the miR-138-5p/CXCL12 axis. | LncRNA GAS5 modulates Schwann cell function and enhances facial nerve injury repair via the miR-138-5p/CXCL12 axis.
Zhu J, Ouyang X, Liu Y, Qian Y, Chen Y, Xu B. | 10/11/2024 |
| GAS5, a long noncoding RNA, contributes to annulus fibroblast osteogenic differentiation and apoptosis in intervertebral disk degeneration via the miR-221-3p/SOX11 axis. | GAS5, a long noncoding RNA, contributes to annulus fibroblast osteogenic differentiation and apoptosis in intervertebral disk degeneration via the miR-221-3p/SOX11 axis.
Liu Q, Luo J, Wang H, Zhang L, Guo J, Jin G., Free PMC Article | 03/6/2024 |
| Silencing of Long Noncoding RNA GAS5 Blocks Experimental Cerebral Ischemia-Reperfusion Injury by Restraining AQP4 Expression via the miR-1192/STAT5A Axis. | Silencing of Long Noncoding RNA GAS5 Blocks Experimental Cerebral Ischemia-Reperfusion Injury by Restraining AQP4 Expression via the miR-1192/STAT5A Axis.
Jiang Z, Liu M, Huang D, Cai Y, Zhou Y. | 11/5/2022 |
| LncRNA growth arrest specific transcript 5 inhibits the growth of pituitary neuroendocrine tumors via miR-27a-5p/cylindromatosis axis. | LncRNA growth arrest specific transcript 5 inhibits the growth of pituitary neuroendocrine tumors via miR-27a-5p/cylindromatosis axis.
Wang H, Wu B, Wang H, Jiang C, Liu Z., Free PMC Article | 04/30/2022 |
| Downregulation of lncRNA GAS5 prevents mitochondrial apoptosis and hypoxic-ischemic brain damage in neonatal rats through the microRNA-128-3p/Bax/Akt/GSK-3beta axis. | Downregulation of lncRNA GAS5 prevents mitochondrial apoptosis and hypoxic-ischemic brain damage in neonatal rats through the microRNA-128-3p/Bax/Akt/GSK-3β axis.
Wang L, Zhang Z, Wang H. | 03/12/2022 |
| Long Non-coding RNA GAS5 Worsens Coronary Atherosclerosis Through MicroRNA-194-3p/TXNIP Axis. | Long Non-coding RNA GAS5 Worsens Coronary Atherosclerosis Through MicroRNA-194-3p/TXNIP Axis.
Li Y, Geng Y, Zhou B, Wu X, Zhang O, Guan X, Xue Y, Li S, Zhuang X, Zhou J, Chang M, Miao G, Wang L., Free PMC Article | 12/11/2021 |
| Contribution of Growth Arrest-Specific 5/miR-674 to the Hypothalamus Pituitary Adrenal Axis Regulation Effect by Electroacupuncture following Trauma. | Contribution of Growth Arrest-Specific 5/miR-674 to the Hypothalamus Pituitary Adrenal Axis Regulation Effect by Electroacupuncture following Trauma.
Zhu J, Guo C, Lu P, Shao S, Tu B. | 11/6/2021 |
| MeCP2 inactivation of LncRNA GAS5 triggers cardiac fibroblasts activation in cardiac fibrosis. | MeCP2 inactivation of LncRNA GAS5 triggers cardiac fibroblasts activation in cardiac fibrosis.
Tao H, Shi P, Zhao XD, Xuan HY, Ding XS. | 10/23/2021 |
| LncRNA-GAS5 regulates PDCD4 expression and mediates myocardial infarction-induced cardiomyocytes apoptosis via targeting MiR-21. | LncRNA-GAS5 regulates PDCD4 expression and mediates myocardial infarction-induced cardiomyocytes apoptosis via targeting MiR-21.
Zhou XH, Chai HX, Bai M, Zhang Z., Free PMC Article | 08/28/2021 |
| Down-regulation of lncRNA Gas5 promotes hypoxia-induced pulmonary arterial smooth muscle cell proliferation by regulating KCNK3 expression. | Down-regulation of lncRNA Gas5 promotes hypoxia-induced pulmonary arterial smooth muscle cell proliferation by regulating KCNK3 expression.
Hao X, Li H, Zhang P, Yu X, Jiang J, Chen S. | 05/15/2021 |
| GAS5 regulates diabetic cardiomyopathy via miR2213p/p27 axisassociated autophagy. | GAS5 regulates diabetic cardiomyopathy via miR‑221‑3p/p27 axis‑associated autophagy.
Chen D, Zhang M., Free PMC Article | 05/15/2021 |
| GAS5 knockdown ameliorates apoptosis and inflammatory response by modulating miR-26b-5p/Smad1 axis in cerebral ischaemia/reperfusion injury. | GAS5 knockdown ameliorates apoptosis and inflammatory response by modulating miR-26b-5p/Smad1 axis in cerebral ischaemia/reperfusion injury.
Shangguan Y, Han J, Su H. | 05/8/2021 |
| DNMT1 Methylation of LncRNA GAS5 Leads to Cardiac Fibroblast Pyroptosis via Affecting NLRP3 Axis. | DNMT1 Methylation of LncRNA GAS5 Leads to Cardiac Fibroblast Pyroptosis via Affecting NLRP3 Axis.
She Q, Shi P, Xu SS, Xuan HY, Tao H, Shi KH, Yang Y. | 04/3/2021 |
| Effect of lncRNA GAS5 on rats with acute myocardial infarction through regulating miR-21. | Effect of lncRNA GAS5 on rats with acute myocardial infarction through regulating miR-21.
Zhang JC, Xia L, Jiang Y, Wu DQ, Liu SC, Zhou XN, Zhang FX. | 12/19/2020 |
| Long noncoding RNA GAS5 regulates myocardial ischemiareperfusion injury through the PI3K/AKT apoptosis pathway by sponging miR5325p. | Long non‑coding RNA GAS5 regulates myocardial ischemia‑reperfusion injury through the PI3K/AKT apoptosis pathway by sponging miR‑532‑5p.
Han Y, Wu N, Xia F, Liu S, Jia D., Free PMC Article | 11/21/2020 |
| LncRNAGAS5 sponges miRNA-221 to promote neurons apoptosis by up-regulated PUMA under hypoxia condition. | LncRNAGAS5 sponges miRNA-221 to promote neurons apoptosis by up-regulated PUMA under hypoxia condition.
Zhou XB, Lai LF, Xie GB, Ding C, Xu X, Wang Y. | 11/21/2020 |
| Effect of lncRNA GAS5 on the apoptosis of neurons via the notch1 signaling pathway in rats with cerebral infarction. | Effect of lncRNA GAS5 on the apoptosis of neurons via the notch1 signaling pathway in rats with cerebral infarction.
Zhao JH, Wang B, Wang XH, Xu CW. | 10/24/2020 |
| lncRNA GAS5 regulates myocardial infarction by targeting the miR-525-5p/CALM2 axis. | lncRNA GAS5 regulates myocardial infarction by targeting the miR-525-5p/CALM2 axis.
Zhang Y, Hou YM, Gao F, Xiao JW, Li CC, Tang Y. | 10/3/2020 |
| Down-regulation of GAS5 ameliorates myocardial ischaemia/reperfusion injury via the miR-335/ROCK1/AKT/GSK-3beta axis. | Down-regulation of GAS5 ameliorates myocardial ischaemia/reperfusion injury via the miR-335/ROCK1/AKT/GSK-3β axis.
Wu N, Zhang X, Bao Y, Yu H, Jia D, Ma C., Free PMC Article | 09/26/2020 |
| role of long-chain noncoding RNA growth-arrest specific transcript 5 (GAS5) in homocysteine-induced cardiac microvascular endothelial cells (CMECs) injury | Long-chain noncoding RNA GAS5 mediates oxidative stress in cardiac microvascular endothelial cells injury.
Diao L, Bai L, Jiang X, Li J, Zhang Q. | 06/13/2020 |
| We found abundant GAS5 expression and a reduction in RGC density in the retinal tissues of glaucoma rats. Silencing of GAS5 led to increased EZH2 expression and decreased ABCA1 expression in RGCs. In addition, upregulation of EZH2 promoted trimethylation of lysine 27 on histone H3, thereby suppressing ABCA1 expression and eventually leading to the inhibition of RGC apoptosis. | Silencing of GAS5 Alleviates Glaucoma in Rat Models by Reducing Retinal Ganglion Cell Apoptosis.
Zhou RR, Li HB, You QS, Rong R, You ML, Xiong K, Huang JF, Xia XB, Ji D. | 06/6/2020 |
| GAS5 directly binds to p53 and p300, stabilizes p53-p300 interaction, and thus regulates VSMC cell survival via induction of p53-downstream target genes. Local delivery of GAS5 via adenoviral vector suppresses balloon injury-induced neointima formation along with an increased expression of p53 and apoptosis in neointimal smooth muscle cells. | LncRNA GAS5 regulates vascular smooth muscle cell cycle arrest and apoptosis via p53 pathway.
Tang R, Mei X, Wang YC, Cui XB, Zhang G, Li W, Chen SY., Free PMC Article | 05/9/2020 |
| Results showed that the levels of GAS5, NR024118 and MRNR026574 were increased in the myocardium of hypertensive rats, suggesting that the three lncRNAs participate in the pathogenesis of hypertensive cardiac remodeling. | Aberrant expression of long noncoding RNAs in the serum and myocardium of spontaneous hypertensive rats.
Wu Y, Zhang Z, Ren S, Li K, Ning Q, Jiang X. | 04/25/2020 |
| GAS5 promotes myocardial apoptosis in myocardial ischemia-reperfusion injury by upregulating LAS1 expression via p38/MAPK pathway. | GAS5 promotes myocardial apoptosis in myocardial ischemia-reperfusion injury via upregulating LAS1 expression.
Liu SD, Meng WX, Xu L, Chi C, Sun X, Liu HY. | 11/23/2019 |
| Intracerebroventricular injection of GAS5 shRNA significantly decreased brain GAS5 expression, reduced brain infarct size, and improved neurological function recovery. Collectively, this study suggests a promising therapeutic approach of GAS5 inhibition in the treatment of neonatal HIBD. | GAS5 silencing protects against hypoxia/ischemia-induced neonatal brain injury.
Zhao RB, Zhu LH, Shu JP, Qiao LX, Xia ZK. | 03/24/2018 |