| Ultrastructural aberrations, histological disruption and upregulation of the VEGF, CD34 and ASMA immunoexpression in the myocardium of anemic albino rats. | Ultrastructural aberrations, histological disruption and upregulation of the VEGF, CD34 and ASMA immunoexpression in the myocardium of anemic albino rats.
Ali EMT, El-Sayed SM, Elbastawisy YM. | 01/15/2022 |
| The expression of alpha-SMA during cardiac fibroblast differentiation was regulated by demethylation of its gene sequence through the inhibition of DNMT1 expression. | DNA methylation regulates α-smooth muscle actin expression during cardiac fibroblast differentiation.
He Y, Ling S, Sun Y, Sheng Z, Chen Z, Pan X, Ma G. | 04/4/2020 |
| miR21 regulates expression of alphaSMA and collagen I in activated rat hepatic stellate cells by directly targeting Smad7. | miR‑21 promotes α‑SMA and collagen I expression in hepatic stellate cells via the Smad7 signaling pathway.
Fu RQ, Hu DP, Hu YB, Hong L, Sun QF, Ding JG. | 05/19/2018 |
| considering the steroid hormone imbalance in late life period, as well as, the role of this imbalance in prostatic lesion development and progression, the aim of the study herein was to characterize and correlate prolactin, EGFR, alpha-actin and vimentin immunoreactivity in the prostatic epithelium and stroma of elderly rats, following steroid hormone imbalance. | Prolactin, EGFR, vimentin and α-actin profiles in elderly rat prostate subjected to steroid hormonal imbalance.
Hetzl AC, Montico F, Kido LA, Cagnon VH. | 03/25/2017 |
| Data suggest that the expression of actin alpha 2 smooth muscle (alpha-SMA) plays certain roles in the neuroma-associated pain, either as a direct cause of pain or as an indirect marker of existence of local mechanical stimuli. | Significance of alpha smooth muscle actin expression in traumatic painful neuromas: a pilot study in rats.
Weng W, Zhao B, Lin D, Gao W, Li Z, Yan H., Free PMC Article | 02/4/2017 |
| TGF-beta1 and alpha-SMA expression is reduced in a rat model of hepatic fibrosis treated with antigenic peptide vaccine | A Targeted Multiple Antigenic Peptide Vaccine Augments the Immune Response to Self TGF-β1 and Suppresses Ongoing Hepatic Fibrosis.
Li Y, Wang W, Jia X, Zhai S, Wang X, Wang Y, Dang S. | 04/30/2016 |
| Expressions of M2R and M3R mRNA were increased in urothelial cells and decreased in detrusor muscles following chronic cystitis. | Laser-capture microdissection for analysis of cell type-specific gene expression of muscarinic receptor subtypes in the rat bladder with cyclophosphamide-induced cystitis.
Sugino Y, O'Malley KJ, Wang Z, Tyagi P, Birder LA, Ogawa O, Yoshimura N. | 12/19/2015 |
| Smooth muscle alpha-actin is present in the cervix of virgin, 11 day, and 20 day pregnant rats. | The persistence of active smooth muscle in the female rat cervix through pregnancy.
Ferland DJ, Darios ES, Watts SW. | 04/11/2015 |
| Data suggest that the myosin-II mediated drebrin A-actin exodus might be an initial event in chemical long-term potentiation (LTP) induction, triggering actin polymerization and spine enlargement. | Myosin II ATPase activity mediates the long-term potentiation-induced exodus of stable F-actin bound by drebrin A from dendritic spines.
Mizui T, Sekino Y, Yamazaki H, Ishizuka Y, Takahashi H, Kojima N, Kojima M, Shirao T., Free PMC Article | 12/6/2014 |
| Acta2 is important for myofibroblast cells motility, contraction and regulation of signaling processes during wound healing. | Smooth muscle α actin (Acta2) and myofibroblast function during hepatic wound healing.
Rockey DC, Weymouth N, Shi Z., Free PMC Article | 08/9/2014 |
| Data from several animal models suggest that up-regulation of expression of Tgfb1 (transforming growth factor beta 1) and Acta2 in proximal tubular cells is key to development of renal tubular fibrosis in chronic kidney disease/renal hypertension. | Indoxyl sulfate-induced activation of (pro)renin receptor is involved in expression of TGF-β1 and α-smooth muscle actin in proximal tubular cells.
Saito S, Shimizu H, Yisireyili M, Nishijima F, Enomoto A, Niwa T. | 06/21/2014 |
| Smooth muscle actin expression increased during lung injury induced by hyperoxia, and could play an important role in pulmonary fibrosis remodeling. | [The expression of α-smooth muscle actin during the lung injury induced by hyperoxia].
Fu YQ, Liu CJ, Li J, Hu L, Lu ZY, Xu F. | 08/3/2013 |
| Smooth muscle alpha-actin was increased on day 9 of bleomycin induced pulmonary fibrosis in rats, and is involved in the mechanism of N-acetylcysteine alleviation of idiopathic pulmonary fibrosis. | N-acetylcysteine downregulation of lysyl oxidase activity alleviating bleomycin-induced pulmonary fibrosis in rats.
Li S, Yang X, Li W, Li J, Su X, Chen L, Yan G. | 05/4/2013 |
| Hydroxycamptothecin reduced expression of TGFb1, a-SMA and collagen I in rat hepatic satellite cells. | [Effects of hydroxycamptothecin on TGFb1, a-SMA and collagen I expression in rat hepatic satellite cells].
Hu GX, Wan ZY, Shao JL, Zhang Y, Zhang LL, Gong ZJ. | 04/13/2013 |
| Data show that expression of tenascin-C (TNC), matrix metalloproteinase-9 (MMP-9), transforming growth factorbeta1 (TGF-beta1), connective tissue growth factor (CTGF) and alpha smooth muscle cell actin (alphaSMA) peaked at 2 weeks post-immunization. | Characterization of fibrosis-promoting factors and siRNA-mediated therapies in C-protein-induced experimental autoimmune myocarditis.
Matsumoto Y, Niimi N, Kohyama K. | 04/6/2013 |
| novel populations of alphaSMA+ precursors of pericytes are born on the subventricular zones then migrate into the peri-infarct region | A novel population of α-smooth muscle actin-positive cells activated in a rat model of stroke: an analysis of the spatio-temporal distribution in response to ischemia.
Sharma V, Ling TW, Rewell SS, Hare DL, Howells DW, Kourakis A, Wookey PJ., Free PMC Article | 01/12/2013 |
| Tendon cells are capable of actively contracting lax tendons through an alpha smooth muscle actin-based mechanism. | Re-establishment of cytoskeletal tensional homeostasis in lax tendons occurs through an actin-mediated cellular contraction of the extracellular matrix.
Gardner K, Lavagnino M, Egerbacher M, Arnoczky SP. | 12/22/2012 |
| Hepatocyte growth factor can relieve chronic renal failure, and this protection is associated with the down-regulation of alpha-SMA expression in mesangial cells and renal interstitium. | Hepatocyte growth factor-induced amelioration in chronic renal failure is associated with reduced expression of α-smooth muscle actin.
Wang HY, Yang LZ, Cui MJ, Gu CM, Zhao Y, Chen Y, Zhao D, Li TS, Chi B. | 12/8/2012 |
| CTGF and alpha-SMA could play an important role in the development of pulmonary fibrosis caused by paraquat poisoning. | [Role of connective tissue growth factor and α-smooth muscle actin in pulmonary fibrosis among acute paraquat poisoned rats].
Huang M, Qi XJ, Zhang P, Chang XL, Wu Q, Zhou ZJ. | 08/25/2012 |
| High fat diet may induce lipid droplet deposit in renal tubular cells by up-regulating expression of SREBP-1, which causes extracellular matrix accumulation by increasing the expression of TGF-beta1 and alpha-SMA. | [High fat diet induced the expression of SREBP-1, TGF-beta1 and alpha-SMA in renal tubular cells and extracellular matrix accumulation in Wistar rats].
Hao J, Liu SX, Wei JY, Yao HY, Duan HJ. | 06/9/2012 |
| Leptin potentiates acetaldehyde-induced hepatic stellate cell activation and transdifferentiation as evidenced by increased alpha-smooth muscle actin expression. | Leptin and acetaldehyde synergistically promotes αSMA expression in hepatic stellate cells by an interleukin 6-dependent mechanism.
Liu Y, Brymora J, Zhang H, Smith B, Ramezani-Moghadam M, George J, Wang J. | 03/10/2012 |
| The results suggest that alpha-SMA containing stress fibers contribute to myofibroblast arrhythmogeneicity. After ablation of this cytoskeletal component, cells lose their arrhythmic effects on cardiomyocytes. | Abolishing myofibroblast arrhythmogeneicity by pharmacological ablation of α-smooth muscle actin containing stress fibers.
Rosker C, Salvarani N, Schmutz S, Grand T, Rohr S. | 12/17/2011 |
| alpha-SMA expression in renal interstitial fibroblasts, i.e., myofibroblast transdifferentiation, accelerates the contraction of the tubulointerstitial fibrosis tissue via the Ca(2)+-dependent pathway | Significance of α-SMA in myofibroblasts emerging in renal tubulointerstitial fibrosis.
Ina K, Kitamura H, Tatsukawa S, Fujikura Y. | 10/1/2011 |
| CTGF mRNA expression in NRK52E cells was significantly associated with alpha-SMA mRNA expression. | [Effects of pioglitazone on the transdifferentiation and CTGF expression of renal tubular epithelial-myofibroblast in vitro].
Pu L, Fan JM. | 05/28/2011 |
| There was a significant increase in the expression of both TTF-1 and T1alpha mRNA in the IGF-2 group, in comparison to the control group after 48 h of culture. | Effect of insulin-like growth factors on lung development in a nitrofen-induced CDH rat model.
Esumi G, Masumoto K, Teshiba R, Nagata K, Kinoshita Y, Yamaza H, Nonaka K, Taguchi T. | 05/28/2011 |