| Control of Arabidopsis shoot stem cell homeostasis by two antagonistic CLE peptide signalling pathways. | Control of Arabidopsis shoot stem cell homeostasis by two antagonistic CLE peptide signalling pathways.
Schlegel J, Denay G, Wink R, Pinto KG, Stahl Y, Schmid J, Blümke P, Simon RG., Free PMC Article | 01/22/2022 |
| WUSCHEL: the versatile protein in the shoot apical meristem. | WUSCHEL: the versatile protein in the shoot apical meristem.
Xu L. | 11/27/2021 |
| WUSCHEL in the shoot apical meristem: old player, new tricks. | WUSCHEL in the shoot apical meristem: old player, new tricks.
Lopes FL, Galvan-Ampudia C, Landrein B. | 05/29/2021 |
| WUSCHEL triggers innate antiviral immunity in plant stem cells. | WUSCHEL triggers innate antiviral immunity in plant stem cells.
Wu H, Qu X, Dong Z, Luo L, Shao C, Forner J, Lohmann JU, Su M, Xu M, Liu X, Zhu L, Zeng J, Liu S, Tian Z, Zhao Z. | 11/21/2020 |
| Structural basis for the complex DNA binding behavior of the plant stem cell regulator WUSCHEL. | Structural basis for the complex DNA binding behavior of the plant stem cell regulator WUSCHEL.
Sloan J, Hakenjos JP, Gebert M, Ermakova O, Gumiero A, Stier G, Wild K, Sinning I, Lohmann JU., Free PMC Article | 08/15/2020 |
| KNU integrates initial transcriptional repression with polycomb-mediated stable silencing of WUS. | Integration of Transcriptional Repression and Polycomb-Mediated Silencing of WUSCHEL in Floral Meristems.
Sun B, Zhou Y, Cai J, Shang E, Yamaguchi N, Xiao J, Looi LS, Wee WY, Gao X, Wagner D, Ito T., Free PMC Article | 05/16/2020 |
| In apical stem cells, WUSCHEL transcription factor confers resistance to auxin mediated differentiation by rheostatically controlling the auxin signaling and response pathway. WUSCHEL acts via regulation of histone acetylation at target loci, including those with functions in the auxin pathway. | WUSCHEL acts as an auxin response rheostat to maintain apical stem cells in Arabidopsis.
Ma Y, Miotk A, Šutiković Z, Ermakova O, Wenzl C, Medzihradszky A, Gaillochet C, Forner J, Utan G, Brackmann K, Galván-Ampudia CS, Vernoux T, Greb T, Lohmann JU., Free PMC Article | 03/7/2020 |
| The S-acylated form of C4 interacts with CLAVATA 1 (CLV1), an important receptor kinase in meristem maintenance, and consequentially affects the expression of WUSCHEL, a major target of CLV1. | S-acylation of a geminivirus C4 protein is essential for regulating the CLAVATA pathway in symptom determination.
Li H, Zeng R, Chen Z, Liu X, Cao Z, Xie Q, Yang C, Lai J., Free PMC Article | 10/19/2019 |
| Study find that WUSCHEL, a key gene required for apical meristem maintenance, is a cytokinin-dependent type-B ARABIDOPSIS RESPONSE REGULATORS target gene, demonstrating the importance of the cytokinin transcription factor network in shoot development. | A B-ARR-mediated cytokinin transcriptional network directs hormone cross-regulation and shoot development.
Xie M, Chen H, Huang L, O'Neil RC, Shokhirev MN, Ecker JR., Free PMC Article | 12/22/2018 |
| Cytokinin signaling in the rib meristem acts through the transcriptional regulatory domains, the acidic domain and the WUSCHEL-box, to stabilize the WUS protein. | Cytokinin stabilizes WUSCHEL by acting on the protein domains required for nuclear enrichment and transcription.
Snipes SA, Rodriguez K, DeVries AE, Miyawaki KN, Perales M, Xie M, Reddy GV., Free PMC Article | 06/23/2018 |
| ARR12 binds to the promoter of WUS. | ARR12 promotes de novo shoot regeneration in Arabidopsis thaliana via activation of WUSCHEL expression.
Dai X, Liu Z, Qiao M, Li J, Li S, Xiang F. | 06/2/2018 |
| WUS is regulated by a balance between positive regulation by cytokinin and negative regulation by CLAVATA protein. | The Mobile bypass Signal Arrests Shoot Growth by Disrupting Shoot Apical Meristem Maintenance, Cytokinin Signaling, and WUS Transcription Factor Expression.
Lee DK, Parrott DL, Adhikari E, Fraser N, Sieburth LE., Free PMC Article | 03/10/2018 |
| Dynamic expression reveals a two-step patterning of WUS and CLV3 during axillary shoot meristem formation in Arabidopsis | Dynamic expression reveals a two-step patterning of WUS and CLV3 during axillary shoot meristem formation in Arabidopsis.
Xin W, Wang Z, Liang Y, Wang Y, Hu Y. | 12/30/2017 |
| results provide important insights into the molecular framework for cytokinin-directed shoot regeneration and reveal a two-step mechanism for de novo activation of WUS. | A Two-Step Model for de Novo Activation of WUSCHEL during Plant Shoot Regeneration.
Zhang TQ, Lian H, Zhou CM, Xu L, Jiao Y, Wang JW., Free PMC Article | 12/16/2017 |
| there is a positive feedback regulation between WUS and OBE3 that contributes to shoot meristem homeostasis | OBE3 and WUS Interaction in Shoot Meristem Stem Cell Regulation.
Lin TF, Saiga S, Abe M, Laux T., Free PMC Article | 07/29/2017 |
| The interplay between cytokinin signaling, WUS/CLV feedback loop and boundary signals can account for positioning of the WUS expression in the process of Arabidopsis thaliana shoot apical meristem patterning. | Centering the Organizing Center in the Arabidopsis thaliana Shoot Apical Meristem by a Combination of Cytokinin Signaling and Self-Organization.
Adibi M, Yoshida S, Weijers D, Fleck C., Free PMC Article | 07/30/2016 |
| The branching ovules of the mutant resemble those of some fossil gymnosperms, implicating BEL1 and HD-ZIPIII genes as players in the evolution of the unbranched ovule form in extant angiosperms. | CORONA, PHABULOSA and PHAVOLUTA collaborate with BELL1 to confine WUSCHEL expression to the nucellus in Arabidopsis ovules.
Yamada T, Sasaki Y, Hashimoto K, Nakajima K, Gasser CS. | 07/16/2016 |
| The stem cell niche in Arabidopsis copes with environmental hazards by enhancing the IRES-dependent translation of WUS mRNA under the control of the AtLa1 protein. | AtLa1 protein initiates IRES-dependent translation of WUSCHEL mRNA and regulates the stem cell homeostasis of Arabidopsis in response to environmental hazards.
Cui Y, Rao S, Chang B, Wang X, Zhang K, Hou X, Zhu X, Wu H, Tian Z, Zhao Z, Yang C, Huang T. | 07/2/2016 |
| stem cell specification pathway is normally repressed by the activity of the HD-zip III transcription factors PHABULOSA (PHB), PHAVOLUTA (PHV) and CORONA (CNA). | A WUSCHEL-Independent Stem Cell Specification Pathway Is Repressed by PHB, PHV and CNA in Arabidopsis.
Lee C, Clark SE., Free PMC Article | 02/6/2016 |
| In the floral meristem, the binding of AG to WUS is reduced in top1a-2, which results in reduced H3K27me3 levels at WUS and prolonged WUS expression, and consequently loss of floral determinacy. | DNA topoisomerase I affects polycomb group protein-mediated epigenetic regulation and plant development by altering nucleosome distribution in Arabidopsis.
Liu X, Gao L, Dinh TT, Shi T, Li D, Wang R, Guo L, Xiao L, Chen X., Free PMC Article | 07/25/2015 |
| Data indicate that the stem cell inducing transcription factor WUSCHEL (WUS) moves to the stem cells via plasmodesmata in a highly regulated fashion and that this movement is required for WUS function. | A mechanistic framework for noncell autonomous stem cell induction in Arabidopsis.
Daum G, Medzihradszky A, Suzaki T, Lohmann JU., Free PMC Article | 05/2/2015 |
| AtWus may therefore increase the differentiation potential of cotton callus by triggering the auxin transport and signaling pathways. | AtWuschel promotes formation of the embryogenic callus in Gossypium hirsutum.
Zheng W, Zhang X, Yang Z, Wu J, Li F, Duan L, Liu C, Lu L, Zhang C, Li F., Free PMC Article | 10/18/2014 |
| GRP23 expression can be activated by WUS. | Ectopic expression of WUS in hypocotyl promotes cell division via GRP23 in Arabidopsis.
Zhang D, Wang X, Wang M, Li J, Guo X, Chong K, Xu Y., Free PMC Article | 07/19/2014 |
| HECATE1 (HEC1) is a target of WUS and that it contributes to SAM function by promoting stem cell proliferation, while antagonizing niche cell activity. HEC1 represses the stem cell regulators WUS and CLAVATA3 (CLV3) | A regulatory framework for shoot stem cell control integrating metabolic, transcriptional, and phytohormone signals.
Schuster C, Gaillochet C, Medzihradszky A, Busch W, Daum G, Krebs M, Kehle A, Lohmann JU. | 04/26/2014 |
| Strong upregulation of WUS in the inflorescence meristem leads to ectopic expression of the AGAMOUS homeotic gene to a level that switches cell fate from floral meristem founder cell to carpel founder cell. | The ERECTA receptor kinase regulates Arabidopsis shoot apical meristem size, phyllotaxy and floral meristem identity.
Mandel T, Moreau F, Kutsher Y, Fletcher JC, Carles CC, Eshed Williams L., Free PMC Article | 04/12/2014 |