| CEACAM8 interacts with CEACAM1 inhibiting TLR2-triggered immune responses | Soluble CEACAM8 interacts with CEACAM1 inhibiting TLR2-triggered immune responses.
Singer BB, Opp L, Heinrich A, Schreiber F, Binding-Liermann R, Berrocal-Almanza LC, Heyl KA, Müller MM, Weimann A, Zweigner J, Slevogt H., Free PMC Article | 01/17/2015 |
| the transmembrane domain is an important determinant of CEACAM1-4S functionality | The transmembrane domain of CEACAM1-4S is a determinant of anchorage independent growth and tumorigenicity.
Lawson EL, Mills DR, Brilliant KE, Hixson DC., Free PMC Article | 05/19/2012 |
| Insulin acutely reduces hepatic FAS activity by inducing phosphorylation of the carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1) and its interaction with FAS. | Insulin acutely decreases hepatic fatty acid synthase activity.
Najjar SM, Yang Y, Fernström MA, Lee SJ, Deangelis AM, Rjaily GA, Al-Share QY, Dai T, Miller TA, Ratnam S, Ruch RJ, Smith S, Lin SH, Beauchemin N, Oyarce AM. | 07/29/2011 |
| ovariectomy decreases the mineralization process and the osteocalcin expression during the chronology of the alveolar healing process that is not totally recovered with estrogen replacement or raloxifene treatment. | Osteocalcin immunolabeling during the alveolar healing process in ovariectomized rats treated with estrogen or raloxifene.
Luvizuto ER, Dias SM, Queiroz TP, Okamoto T, Garcia IR Jr, Okamoto R, Dornelles RC. | 07/5/2010 |
| Transmembrane signaling by CEACAM1 operates by alteration of the monomer/dimer equilibrium, which leads to changes in the SHP-2 phosphatase/c-Src kinase-binding ratio. | Homophilic adhesion and CEACAM1-S regulate dimerization of CEACAM1-L and recruitment of SHP-2 and c-Src.
Müller MM, Klaile E, Vorontsova O, Singer BB, Obrink B., Free PMC Article | 01/21/2010 |
| A mechanism involving adhesion-influenced dynamic changes of CEACAM1 microcluster organization exists in epithelial cells. | The CEACAM1 N-terminal Ig domain mediates cis- and trans-binding and is essential for allosteric rearrangements of CEACAM1 microclusters.
Klaile E, Vorontsova O, Sigmundsson K, Müller MM, Singer BB, Ofverstedt LG, Svensson S, Skoglund U, Obrink B., Free PMC Article | 01/21/2010 |
| CEACAM1 is a direct target of SOX9 in the colon epithelium | CEACAM1, a SOX9 direct transcriptional target identified in the colon epithelium.
Zalzali H, Naudin C, Bastide P, Quittau-Prévostel C, Yaghi C, Poulat F, Jay P, Blache P. | 01/21/2010 |
| PDIP38 can shuttle between the cytoplasmic and the nuclear compartments and that its subcellular localization is regulated by CEACAM1 | The cell adhesion receptor carcinoembryonic antigen-related cell adhesion molecule 1 regulates nucleocytoplasmic trafficking of DNA polymerase delta-interacting protein 38.
Klaile E, Müller MM, Kannicht C, Otto W, Singer BB, Reutter W, Obrink B, Lucka L. | 01/21/2010 |
| Two novel splice variants, designated CEACAM1-4C1 and CEACAM1-4C2, lacking the transmembrane region, were identified in this study. | Secreted CEACAM1 splice variants in rat cell lines and in vivo in rat serum.
Budt M, Michely B, Müller MM, Reutter W, Lucka L. | 01/21/2010 |
| CEACAM1 influences the resolution of inflammation by prolonging the survival of rat granulocytes. | CEACAM1 (CD66a) mediates delay of spontaneous and Fas ligand-induced apoptosis in granulocytes.
Singer BB, Klaile E, Scheffrahn I, Müller MM, Kammerer R, Reutter W, Obrink B, Lucka L. | 01/21/2010 |
| the transmembrane domain of CEACAM1 is responsible for the Cdc42-induced targeting at cell-cell contacts | Distinct Rho GTPase activities regulate epithelial cell localization of the adhesion molecule CEACAM1: involvement of the CEACAM1 transmembrane domain.
Fournès B, Farrah J, Olson M, Lamarche-Vane N, Beauchemin N., Free PMC Article | 01/21/2010 |
| Both long and short cytoplasmic domain isoforms of Ceacam1 are expressed in rat neutrophils, B cells, and T-cells. | Carcinoembryonic antigen-related cell adhesion molecule 1 expression and signaling in human, mouse, and rat leukocytes: evidence for replacement of the short cytoplasmic domain isoform by glycosylphosphatidylinositol-linked proteins in human leukocytes.
Singer BB, Scheffrahn I, Heymann R, Sigmundsson K, Kammerer R, Obrink B. | 01/21/2010 |
| the N-domain of CEACAM1 shows evidence of recombination | Two variable regions in carcinoembryonic antigen-related cell adhesion molecule1 N-terminal domains located in or next to monoclonal antibody and adhesion epitopes show evidence of recombination in rat but not in human.
Comegys MM, Lin SH, Rand D, Britt D, Flanagan D, Callanan H, Brilliant K, Hixson DC. | 01/21/2010 |
| HIF-1/vEGF/CEACAM-1 pathway might be important for hypoxia-induced angiogenesis in the heart during hypoxic preconditioning | Gene expression profiles in hypoxic preconditioning using cDNA microarray analysis: altered expression of an angiogenic factor, carcinoembryonic antigen-related cell adhesion molecule 1.
Chen WJ, Chen HW, Yu SL, Huang CH, Wang TD, Chen JJ, Chien CT, Chen HY, Yang PC, Lee YT. | 01/21/2010 |
| CEACAM1 mediates contact inhibition of proliferation in cells that are constantly exposed to growth factors, but co-activates growth-factor-induced proliferation in cells that have been starved for growth factors. | Control of density-dependent, cell state-specific signal transduction by the cell adhesion molecule CEACAM1, and its influence on cell cycle regulation.
Scheffrahn I, Singer BB, Sigmundsson K, Lucka L, Obrink B. | 01/21/2010 |