| The FXR1 network acts as a signaling scaffold for actomyosin remodeling. | The FXR1 network acts as a signaling scaffold for actomyosin remodeling.
Chen X, Fansler MM, Janjoš U, Ule J, Mayr C., | 09/16/2024 |
| LLPS of FXR proteins drives replication organelle clustering for beta-coronaviral proliferation. | LLPS of FXR proteins drives replication organelle clustering for β-coronaviral proliferation.
Li M, Hou Y, Zhou Y, Yang Z, Zhao H, Jian T, Yu Q, Zeng F, Liu X, Zhang Z, Zhao YG., Free PMC Article | 04/10/2024 |
| The multifaceted role of Fragile X-Related Protein 1 (FXR1) in cellular processes: an updated review on cancer and clinical applications. | The multifaceted role of Fragile X-Related Protein 1 (FXR1) in cellular processes: an updated review on cancer and clinical applications.
Khan FA, Fang N, Zhang W, Ji S., Free PMC Article | 02/1/2024 |
| FXR1 regulates vascular smooth muscle cell cytoskeleton, VSMC contractility, and blood pressure by multiple mechanisms. | FXR1 regulates vascular smooth muscle cell cytoskeleton, VSMC contractility, and blood pressure by multiple mechanisms.
St Paul A, Corbett C, Peluzzo A, Kelemen S, Okune R, Haines DS, Preston K, Eguchi S, Autieri MV., Free PMC Article | 10/6/2023 |
| Fragile X-Related Protein FXR1 Controls Human Adenovirus Capsid mRNA Metabolism. | Fragile X-Related Protein FXR1 Controls Human Adenovirus Capsid mRNA Metabolism.
Hajikhezri Z, Kaira Y, Schubert E, Darweesh M, Svensson C, Akusjärvi G, Punga T., Free PMC Article | 03/6/2023 |
| FXR1 facilitates axitinib resistance in clear cell renal cell carcinoma via regulating KEAP1/Nrf2 signaling pathway. | FXR1 facilitates axitinib resistance in clear cell renal cell carcinoma via regulating KEAP1/Nrf2 signaling pathway.
Huang H, Zhang J, Jiang P, Xu X, Huang F, Zhao B, Wang X, Zhou L. | 02/13/2023 |
| FMRP, FXR1 protein and Dlg4 mRNA, which are associated with fragile X syndrome, are involved in the ubiquitin-proteasome system. | FMRP, FXR1 protein and Dlg4 mRNA, which are associated with fragile X syndrome, are involved in the ubiquitin-proteasome system.
Shimizu H, Hohjoh H., Free PMC Article | 02/10/2023 |
| Exosomal circZNF451 restrains anti-PD1 treatment in lung adenocarcinoma via polarizing macrophages by complexing with TRIM56 and FXR1. | Exosomal circZNF451 restrains anti-PD1 treatment in lung adenocarcinoma via polarizing macrophages by complexing with TRIM56 and FXR1.
Gao J, Ao YQ, Zhang LX, Deng J, Wang S, Wang HK, Jiang JH, Ding JY., Free PMC Article | 01/14/2023 |
| CircSETD3 mediates acquired resistance to gefitinib in non-small lung cancer cells by FXR1/ECT2 pathway. | CircSETD3 mediates acquired resistance to gefitinib in non-small lung cancer cells by FXR1/ECT2 pathway.
Wen C, Li Y, Huang Y, Wang N, He S, Bao M, Zhou H, Wu L. | 01/11/2023 |
| FXR1-related congenital myopathy: expansion of the clinical and genetic spectrum. | FXR1-related congenital myopathy: expansion of the clinical and genetic spectrum.
Mroczek M, Longman C, Farrugia ME, Kapetanovic Garcia S, Ardicli D, Topaloglu H, Hernández-Laín A, Orhan D, Alikasifoglu M, Duff J, Specht S, Nowak K, Ravenscroft G, Chao K, Valivullah Z, Donkervoort S, Saade D, Bönnemann C, Straub V, Yoon G., Free PMC Article | 10/29/2022 |
| CEP63 upregulates YAP1 to promote colorectal cancer progression through stabilizing RNA binding protein FXR1. | CEP63 upregulates YAP1 to promote colorectal cancer progression through stabilizing RNA binding protein FXR1.
Ling H, Cao CH, Han K, Lv YR, Ma XD, Cao JH, Chen JW, Li S, Lin JL, Fang YJ, Pan ZZ, Xie D, Wang FW. | 10/8/2022 |
| The RNA-binding protein fragile-X mental retardation autosomal 1 (FXR1) modulates glioma cells sensitivity to temozolomide by regulating ferroptosis. | The RNA-binding protein fragile-X mental retardation autosomal 1 (FXR1) modulates glioma cells sensitivity to temozolomide by regulating ferroptosis.
Wei Y, Duan S, Gong F, Li Q. | 04/30/2022 |
| FXR1 can bind with the CFIm25/CFIm68 complex and promote the progression of urothelial carcinoma of the bladder by stabilizing TRAF1 mRNA. | FXR1 can bind with the CFIm25/CFIm68 complex and promote the progression of urothelial carcinoma of the bladder by stabilizing TRAF1 mRNA.
Deng M, Wang N, Li Z, Chen R, Duan J, Peng Y, Wu Z, Zhang Z, Jiang L, Zheng X, Xie D, Wei W, Liu Z, Zhou F., Free PMC Article | 04/16/2022 |
| Over-expression of long non-coding RNA NORAD promotes trophoblastic cell viability, migration, and invasion in preeclampsia via the miR-202-5p/FXR1 axis. | Over-expression of long non-coding RNA NORAD promotes trophoblastic cell viability, migration, and invasion in preeclampsia via the miR-202-5p/FXR1 axis.
Zhang Z, Wang Y. | 04/9/2022 |
| FXR1 regulation of parvalbumin interneurons in the prefrontal cortex is critical for schizophrenia-like behaviors. | FXR1 regulation of parvalbumin interneurons in the prefrontal cortex is critical for schizophrenia-like behaviors.
Shen M, Guo Y, Dong Q, Gao Y, Stockton ME, Li M, Kannan S, Korabelnikov T, Schoeller KA, Sirois CL, Zhou C, Le J, Wang D, Chang Q, Sun QQ, Zhao X., Free PMC Article | 03/19/2022 |
| Fragile X-Related Protein 1 (FXR1) Promotes Trophoblast Migration at Early Pregnancy via Downregulation of GDF-15 Expression. | Fragile X-Related Protein 1 (FXR1) Promotes Trophoblast Migration at Early Pregnancy via Downregulation of GDF-15 Expression.
Hong W, Chen JH, Ma HJ, Li-Li, Li XC., Free PMC Article | 03/12/2022 |
| RNA-binding protein FXR1 drives cMYC translation by recruiting eIF4F complex to the translation start site. | RNA-binding protein FXR1 drives cMYC translation by recruiting eIF4F complex to the translation start site.
George J, Li Y, Kadamberi IP, Parashar D, Tsaih SW, Gupta P, Geethadevi A, Chen C, Ghosh C, Sun Y, Mittal S, Ramchandran R, Rui H, Lopez-Berestein G, Rodriguez-Aguayo C, Leone G, Rader JS, Sood AK, Dey M, Pradeep S, Chaluvally-Raghavan P., Free PMC Article | 02/19/2022 |
| Synergistic tumor inhibition of colon cancer cells by nitazoxanide and obeticholic acid, a farnesoid X receptor ligand. | Synergistic tumor inhibition of colon cancer cells by nitazoxanide and obeticholic acid, a farnesoid X receptor ligand.
Yu J, Yang K, Zheng J, Zhao W, Sun X., Free PMC Article | 02/12/2022 |
| Long noncoding RNA ENST00000508435 promotes migration of breast cancer via FXR 1. | Long noncoding RNA ENST00000508435 promotes migration of breast cancer via FXR 1.
Li L, Jin Y, Wang X, Wang L, Sun Y, Luo Y, Ni X, Lu Q, Wei W, Zhi X, Yu J, Zhu W, Zhou P., Free PMC Article | 12/18/2021 |
| Evidence of an interaction between FXR1 and GSK3beta polymorphisms on levels of Negative Symptoms of Schizophrenia and their response to antipsychotics. | Evidence of an interaction between FXR1 and GSK3β polymorphisms on levels of Negative Symptoms of Schizophrenia and their response to antipsychotics.
Rampino A, Torretta S, Gelao B, Veneziani F, Iacoviello M, Marakhovskaya A, Masellis R, Andriola I, Sportelli L, Pergola G, Minelli A, Magri C, Gennarelli M, Vita A, Beaulieu JM, Bertolino A, Blasi G., Free PMC Article | 11/27/2021 |
| circNRIP1 facilitates keloid progression via FXR1mediated upregulation of miR5033p and miR5035p. | circNRIP1 facilitates keloid progression via FXR1‑mediated upregulation of miR‑503‑3p and miR‑503‑5p.
Wang B, Yin H, Zhang H, Wang T., Free PMC Article | 07/17/2021 |
| Circ_0000079 Decoys the RNA-Binding Protein FXR1 to Interrupt Formation of the FXR1/PRCKI Complex and Decline Their Mediated Cell Invasion and Drug Resistance in NSCLC. | Circ_0000079 Decoys the RNA-Binding Protein FXR1 to Interrupt Formation of the FXR1/PRCKI Complex and Decline Their Mediated Cell Invasion and Drug Resistance in NSCLC.
Chen C, Zhang M, Zhang Y., Free PMC Article | 06/26/2021 |
| FXR1 is a novel MRE11-binding partner and participates in oxidative stress responses. | FXR1 is a novel MRE11-binding partner and participates in oxidative stress responses.
Qi F, Meng Q, Hayashi I, Kobayashi J., Free PMC Article | 06/12/2021 |
| Spatial control of nucleoporin condensation by fragile X-related proteins. | Spatial control of nucleoporin condensation by fragile X-related proteins.
Agote-Aran A, Schmucker S, Jerabkova K, Jmel Boyer I, Berto A, Pacini L, Ronchi P, Kleiss C, Guerard L, Schwab Y, Moine H, Mandel JL, Jacquemont S, Bagni C, Sumara I., Free PMC Article | 04/17/2021 |
| Fragile X-related protein family: a double-edged sword in neurodevelopmental disorders and cancer. | Fragile X-related protein family: a double-edged sword in neurodevelopmental disorders and cancer.
Majumder M, Johnson RH, Palanisamy V., Free PMC Article | 03/13/2021 |