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    KDM7A lysine demethylase 7A [ Homo sapiens (human) ]

    Gene ID: 80853, updated on 27-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Inhibition of KDM2/7 Promotes Notochordal Differentiation of hiPSCs.

    Inhibition of KDM2/7 Promotes Notochordal Differentiation of hiPSCs.
    Diaz-Hernandez ME, Murakami K, Murata S, Khan NM, Shenoy SPV, Henke K, Yamada H, Drissi H., Free PMC Article

    11/7/2024
    The nuclear bodies formed by histone demethylase KDM7A.

    The nuclear bodies formed by histone demethylase KDM7A.
    Ming H, Wang Q, Zhang Y, Ji L, Cheng L, Huo X, Yan Z, Liu Z, Dang Y, Wen B., Free PMC Article

    09/4/2021
    Hsa_circ_002178 Promotes the Growth and Migration of Breast Cancer Cells and Maintains Cancer Stem-like Cell Properties Through Regulating miR-1258/KDM7A Axis.

    Hsa_circ_002178 Promotes the Growth and Migration of Breast Cancer Cells and Maintains Cancer Stem-like Cell Properties Through Regulating miR-1258/KDM7A Axis.
    Li W, Yang X, Shi C, Zhou Z., Free PMC Article

    06/26/2021
    Histone Demethylase KDM7A Regulates Androgen Receptor Activity, and Its Chemical Inhibitor TC-E 5002 Overcomes Cisplatin-Resistance in Bladder Cancer Cells.

    Histone Demethylase KDM7A Regulates Androgen Receptor Activity, and Its Chemical Inhibitor TC-E 5002 Overcomes Cisplatin-Resistance in Bladder Cancer Cells.
    Lee KH, Kim BC, Jeong SH, Jeong CW, Ku JH, Kim HH, Kwak C., Free PMC Article

    02/20/2021
    JHDM1D-AS1 aggravates the development of gastric cancer through miR-450a-2-3p-PRAF2 axis.

    JHDM1D-AS1 aggravates the development of gastric cancer through miR-450a-2-3p-PRAF2 axis.
    Wu M, Liu Y, Pu YS, Ma Y, Wang JH, Liu EQ.

    01/16/2021
    Coordinated demethylation of H3K9 and H3K27 is required for rapid inflammatory responses of endothelial cells.

    Coordinated demethylation of H3K9 and H3K27 is required for rapid inflammatory responses of endothelial cells.
    Higashijima Y, Matsui Y, Shimamura T, Nakaki R, Nagai N, Tsutsumi S, Abe Y, Link VM, Osaka M, Yoshida M, Watanabe R, Tanaka T, Taguchi A, Miura M, Ruan X, Li G, Inoue T, Nangaku M, Kimura H, Furukawa T, Aburatani H, Wada Y, Ruan Y, Glass CK, Kanki Y., Free PMC Article

    12/12/2020
    Histone demethylase KDM7A is required for stem cell maintenance and apoptosis inhibition in breast cancer.

    Histone demethylase KDM7A is required for stem cell maintenance and apoptosis inhibition in breast cancer.
    Meng Z, Liu Y, Wang J, Fan H, Fang H, Li S, Yuan L, Liu C, Peng Y, Zhao W, Wang L, Li J, Feng J.

    10/24/2020
    decreased expression in placenta associated with pre-eclampsia through down-regulating HLA-G

    Decreased expression of JHDMID in placenta is associated with preeclampsia through HLA-G.
    Luo S, Pei J, Li X, Gu W.

    10/26/2019
    KDM7A is potentially a good therapeutic target for prostate cancer drugs.

    Histone demethylase KDM7A controls androgen receptor activity and tumor growth in prostate cancer.
    Lee KH, Hong S, Kang M, Jeong CW, Ku JH, Kim HH, Kwak C.

    02/23/2019
    KDM7A mediates TNF-alpha-induced ICAM1 protein upregulation.

    KDM7A histone demethylase mediates TNF-α-induced ICAM1 protein upregulation by modulating lysosomal activity.
    Choi JY, Jo SA.

    06/3/2017
    G9a promotes H3K27 methylation of the E-cadherin promoter by upregulating PCL3 to increase PRC2 promoter recruitment and by downregulating the H3K27 demethylase KDM7A to silence E-cadherin gene

    G9a orchestrates PCL3 and KDM7A to promote histone H3K27 methylation.
    Pan MR, Hsu MC, Chen LT, Hung WC., Free PMC Article

    12/17/2016
    Histone modifier genes (JMJD1C, RREB1, MINA, KDM7A) alter conotruncal heart phenotypes in 22q11.2 deletion syndrome.

    Histone Modifier Genes Alter Conotruncal Heart Phenotypes in 22q11.2 Deletion Syndrome.
    Guo T, Chung JH, Wang T, McDonald-McGinn DM, Kates WR, Hawuła W, Coleman K, Zackai E, Emanuel BS, Morrow BE., Free PMC Article

    03/26/2016
    increased JHDM1D expression suppresses tumor growth by down-regulating angiogenesis under nutrient starvation

    Increased expression of histone demethylase JHDM1D under nutrient starvation suppresses tumor growth via down-regulating angiogenesis.
    Osawa T, Muramatsu M, Wang F, Tsuchida R, Kodama T, Minami T, Shibuya M., Free PMC Article

    03/10/2012
    KIAA1718 is a dual-specificity histone demethylase that regulates neural differentiation through FGF4.

    Dual-specificity histone demethylase KIAA1718 (KDM7A) regulates neural differentiation through FGF4.
    Huang C, Xiang Y, Wang Y, Li X, Xu L, Zhu Z, Zhang T, Zhu Q, Zhang K, Jing N, Chen CD.

    05/3/2010
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