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    NR4A3 nuclear receptor subfamily 4 group A member 3 [ Homo sapiens (human) ]

    Gene ID: 8013, updated on 27-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    NOR1 promotes the osteoblastic differentiation of human periodontal ligament stem cells via TGF-beta signaling pathway.

    NOR1 promotes the osteoblastic differentiation of human periodontal ligament stem cells via TGF-β signaling pathway.
    Wu Y, Jing H, Li Y, Li M, Zheng Y, Lin Y, Ma G, Cao H, Yang H., Free PMC Article

    08/15/2024
    Potential Roles of Nr4a3-Mediated Inflammation in Immunological and Neurological Diseases.

    Potential Roles of Nr4a3-Mediated Inflammation in Immunological and Neurological Diseases.
    He S, Jiang W, Jiang B, Yu C, Zhao G, Li Y, Qi L, Zhang J, Wang D.

    07/22/2024
    Orphan Nuclear Receptor NR4A3 Promotes Vascular Calcification via Histone Lactylation.

    Orphan Nuclear Receptor NR4A3 Promotes Vascular Calcification via Histone Lactylation.
    Ma W, Jia K, Cheng H, Xu H, Li Z, Zhang H, Xie H, Sun H, Yi L, Chen Z, Duan S, Sano M, Fukuda K, Lu L, Gao F, Zhang R, Yan X.

    05/31/2024
    Orphan Nuclear Receptor Family 4A (NR4A) Members NR4A2 and NR4A3 Selectively Modulate Elements of the Monocyte Response to Buffered Hypercapnia.

    Orphan Nuclear Receptor Family 4A (NR4A) Members NR4A2 and NR4A3 Selectively Modulate Elements of the Monocyte Response to Buffered Hypercapnia.
    Phelan DE, Reddan B, Shigemura M, Sznajder JI, Crean D, Cummins EP., Free PMC Article

    03/20/2024
    RP11-495P10.1 promotes HCC cell proliferation by regulating reprogramming of glucose metabolism and acetylation of the NR4A3 promoter via the PDK1/PDH axis.

    RP11-495P10.1 promotes HCC cell proliferation by regulating reprogramming of glucose metabolism and acetylation of the NR4A3 promoter via the PDK1/PDH axis.
    Liu C, Shi J, Jiang Z, Jiang S, Wu Y, Peng D, Tang J, Guo L., Free PMC Article

    02/14/2024
    Upregulation of NOR-1 in calcified human vascular tissues: impact on osteogenic differentiation and calcification.

    Upregulation of NOR-1 in calcified human vascular tissues: impact on osteogenic differentiation and calcification.
    Ballester-Servera C, Cañes L, Alonso J, Puertas-Umbert L, Vázquez-Sufuentes P, Taurón M, Roselló-Díez E, Marín F, Rodríguez C, Martínez-González J.

    01/16/2024
    Evaluation of mRNA Expressions of TOX and NR4As in CD8+ T cells in Acute Leukemia.

    Evaluation of mRNA Expressions of TOX and NR4As in CD8+ T cells in Acute Leukemia.
    Mohammadi M, Asgarian-Omran H, Najafi B, Najafi A, Valadan R, Karami H, Naderisoraki M, Alizadeforoutan M, Shekarriz R, Tehrani M.

    01/16/2024
    NRF1 Alleviated Oxidative Stress of Glioblastoma Cells by Regulating NOR1.

    NRF1 Alleviated Oxidative Stress of Glioblastoma Cells by Regulating NOR1.
    Wang J, Chen S, Xiang W, Zhu Q, Ren N.

    11/18/2023
    Loss of NOR-1 represses muscle metabolism through mTORC1-mediated signaling and mitochondrial gene expression in C2C12 myotubes.

    Loss of NOR-1 represses muscle metabolism through mTORC1-mediated signaling and mitochondrial gene expression in C2C12 myotubes.
    Paez HG, Ferrandi PJ, Pitzer CR, Mohamed JS, Alway SE.

    07/5/2023
    NR4A3 Expression Is Consistently Absent in Acinic Cell Carcinomas of the Breast: A Potential Nosologic Shift.

    NR4A3 Expression Is Consistently Absent in Acinic Cell Carcinomas of the Breast: A Potential Nosologic Shift.
    Richardson ET, Selenica P, Pareja F, Cin PD, Hanlon E, Weigelt B, Reis-Filho JS, Hornick JL, Jo VY, Schnitt SJ., Free PMC Article

    06/29/2023
    NR4A3 fusions characterize a distinctive peritoneal mesothelial neoplasm of uncertain biological potential with pure adenomatoid/microcystic morphology.

    NR4A3 fusions characterize a distinctive peritoneal mesothelial neoplasm of uncertain biological potential with pure adenomatoid/microcystic morphology.
    Agaimy A, Brcic L, Briski LM, Hung YP, Michal M, Michal M, Nielsen GP, Stoehr R, Rosenberg AE.

    03/16/2023
    A minority of cases of acinic cell carcinoma of the salivary glands are driven by an NR4A2 rearrangement: the diagnostic utility of the assessment of NR4A2 and NR4A3 alterations in salivary gland tumors.

    A minority of cases of acinic cell carcinoma of the salivary glands are driven by an NR4A2 rearrangement: the diagnostic utility of the assessment of NR4A2 and NR4A3 alterations in salivary gland tumors.
    Klubíčková N, Grossmann P, Šteiner P, Baněčková M, Mosaieby E, Koshyk O, Michal M, Leivo I, Skálová A.

    02/18/2023
    Nuclear Receptor Subfamily 4A Signaling as a Key Disease Pathway of CD1c+ Dendritic Cell Dysregulation in Systemic Sclerosis.

    Nuclear Receptor Subfamily 4A Signaling as a Key Disease Pathway of CD1c+ Dendritic Cell Dysregulation in Systemic Sclerosis.
    Servaas NH, Hiddingh S, Chouri E, Wichers CGK, Affandi AJ, Ottria A, Bekker CPJ, Cossu M, Silva-Cardoso SC, van der Kroef M, Hinrichs AC, Carvalheiro T, Vazirpanah N, Beretta L, Rossato M, Bonte-Mineur F, Radstake TRDJ, Kuiper JJW, Boes M, Pandit A., Free PMC Article

    02/4/2023
    BLIMP1 and NR4A3 transcription factors reciprocally regulate antitumor CAR T cell stemness and exhaustion.

    BLIMP1 and NR4A3 transcription factors reciprocally regulate antitumor CAR T cell stemness and exhaustion.
    Jung IY, Narayan V, McDonald S, Rech AJ, Bartoszek R, Hong G, Davis MM, Xu J, Boesteanu AC, Barber-Rotenberg JS, Plesa G, Lacey SF, Jadlowsky JK, Siegel DL, Hammill DM, Cho-Park PF, Berger SL, Haas NB, Fraietta JA., Free PMC Article

    01/28/2023
    Functional association of NR4A3 downregulation with impaired differentiation in myeloid leukemogenesis.

    Functional association of NR4A3 downregulation with impaired differentiation in myeloid leukemogenesis.
    Lin SC, Yao CY, Hsu CA, Lin CT, Calkins MJ, Kuo YY, Tang JL, Tien HF, Wu SJ., Free PMC Article

    09/24/2022
    Matriptase-2/NR4A3 axis switches TGF-beta action toward suppression of prostate cancer cell invasion, tumor growth, and metastasis.

    Matriptase-2/NR4A3 axis switches TGF-β action toward suppression of prostate cancer cell invasion, tumor growth, and metastasis.
    Lin HY, Ko CJ, Lo TY, Wu SR, Lan SW, Huang CA, Lin YC, Lin HH, Tu HF, Lee CF, Hsiao PW, Huang HP, Chen MJ, Chang KH, Lee MS.

    05/21/2022
    Analysis of clinicopathologic features and expression of NR4A3 in sinonasal acinic cell carcinoma.

    Analysis of clinicopathologic features and expression of NR4A3 in sinonasal acinic cell carcinoma.
    Wang H, Zhai C, Zhang C, Liu Q, Zhang H, Sun X, Lin L, Yu H, Wang D.

    05/14/2022
    MiR-501-5p alleviates cardiac dysfunction in septic patients through targeting NR4A3 to prevent its binding with Bcl-2.

    MiR-501-5p alleviates cardiac dysfunction in septic patients through targeting NR4A3 to prevent its binding with Bcl-2.
    Gao L, Zhai Z, Shi Q, Yan J, Zhou L, Wu Y, Zeng Q, Tian G, Li H., Free PMC Article

    05/7/2022
    Knockdown of long noncoding RNA AC245100.4 inhibits the tumorigenesis of prostate cancer cells via the STAT3/NR4A3 axis.

    Knockdown of long noncoding RNA AC245100.4 inhibits the tumorigenesis of prostate cancer cells via the STAT3/NR4A3 axis.
    Liu C, Lin P, Zhao J, Xie H, Li R, Yang X, Wang N, Jia H, Jiang S, Zhang K, Yu X.

    03/26/2022
    NR4A3 and CCL20 clusters dominate the genetic networks in CD146(+) blood cells during acute myocardial infarction in humans.

    NR4A3 and CCL20 clusters dominate the genetic networks in CD146(+) blood cells during acute myocardial infarction in humans.
    Wang YH, Li CX, Stephenson JM, Marrelli SP, Kou YM, Meng DZ, Wu T., Free PMC Article

    02/5/2022
    NR4A3: A Key Nuclear Receptor in Vascular Biology, Cardiovascular Remodeling, and Beyond.

    NR4A3: A Key Nuclear Receptor in Vascular Biology, Cardiovascular Remodeling, and Beyond.
    Martínez-González J, Cañes L, Alonso J, Ballester-Servera C, Rodríguez-Sinovas A, Corrales I, Rodríguez C., Free PMC Article

    01/8/2022
    Minireview: What is Known about SUMOylation Among NR4A Family Members?

    Minireview: What is Known about SUMOylation Among NR4A Family Members?
    Dodat F, Mader S, Lévesque D.

    11/27/2021
    Transcriptional Profiling of Monocytes Deficient in Nuclear Orphan Receptors NR4A2 and NR4A3 Reveals Distinct Signalling Roles Related to Antigen Presentation and Viral Response.

    Transcriptional Profiling of Monocytes Deficient in Nuclear Orphan Receptors NR4A2 and NR4A3 Reveals Distinct Signalling Roles Related to Antigen Presentation and Viral Response.
    Phelan DE, Shigemura M, Aldhafiri S, Mota C, Hall TJ, Sznajder JI, Murphy EP, Crean D, Cummins EP., Free PMC Article

    10/30/2021
    Atypic SUMOylation of Nor1/NR4A3 regulates neural cell viability and redox sensitivity.

    Atypic SUMOylation of Nor1/NR4A3 regulates neural cell viability and redox sensitivity.
    Gagnon J, Caron V, Gyenizse L, Tremblay A.

    08/28/2021
    miR-106b-5p induces immune imbalance of Treg/Th17 in immune thrombocytopenic purpura through NR4A3/Foxp3 pathway.

    miR-106b-5p induces immune imbalance of Treg/Th17 in immune thrombocytopenic purpura through NR4A3/Foxp3 pathway.
    Li JQ, Tian JM, Fan XR, Wang ZY, Ling J, Wu XF, Yang FY, Xia YL., Free PMC Article

    08/28/2021
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