| Role of NOX1 and NOX5 in protein kinase C/reactive oxygen species-mediated MMP-9 activation and invasion in MCF-7 breast cancer cells. | Role of NOX1 and NOX5 in protein kinase C/reactive oxygen species‑mediated MMP‑9 activation and invasion in MCF‑7 breast cancer cells.
Song HK, Kim JM, Noh EM, Youn HJ, Lee YR., Free PMC Article | 09/4/2024 |
| Structural basis of human NOX5 activation. | Structural basis of human NOX5 activation.
Cui C, Jiang M, Jain N, Das S, Lo YH, Kermani AA, Pipatpolkai T, Sun J., Free PMC Article | 06/28/2024 |
| Structure, regulation, and physiological functions of NADPH oxidase 5 (NOX5). | Structure, regulation, and physiological functions of NADPH oxidase 5 (NOX5).
García JG, Ansorena E, Izal I, Zalba G, de Miguel C, Milagro FI., Free PMC Article | 06/29/2023 |
| Ca[2+] -binding-region-dependent cell surface localization of NADPH oxidase Nox5. | Ca(2+) -binding-region-dependent cell surface localization of NADPH oxidase Nox5.
Miyano K, Kajikawa M. | 03/16/2023 |
| NOX2 and NOX5 are increased in cardiac microvascular endothelium of deceased COVID-19 patients. | NOX2 and NOX5 are increased in cardiac microvascular endothelium of deceased COVID-19 patients.
Jiang Z, Wu L, van der Leeden B, van Rossum AC, Niessen HWM, Krijnen PAJ., Free PMC Article | 01/11/2023 |
| Impact of calcium and reactive oxygen species on human sperm function: Role of NOX5. | Impact of calcium and reactive oxygen species on human sperm function: Role of NOX5.
Keshtgar S, Ghani E. | 08/13/2022 |
| Nicotine promotes vascular calcification via intracellular Ca2+-mediated, Nox5-induced oxidative stress, and extracellular vesicle release in vascular smooth muscle cells. | Nicotine promotes vascular calcification via intracellular Ca2+-mediated, Nox5-induced oxidative stress, and extracellular vesicle release in vascular smooth muscle cells.
Petsophonsakul P, Burgmaier M, Willems B, Heeneman S, Stadler N, Gremse F, Reith S, Burgmaier K, Kahles F, Marx N, Natour E, Bidar E, Jacobs M, Mees B, Reutelingsperger C, Furmanik M, Schurgers L., Free PMC Article | 08/6/2022 |
| Independent of Renox, NOX5 Promotes Renal Inflammation and Fibrosis in Diabetes by Activating ROS-Sensitive Pathways. | Independent of Renox, NOX5 Promotes Renal Inflammation and Fibrosis in Diabetes by Activating ROS-Sensitive Pathways.
Jha JC, Dai A, Garzarella J, Charlton A, Urner S, Østergaard JA, Okabe J, Holterman CE, Skene A, Power DA, Ekinci EI, Coughlan MT, Schmidt HHHW, Cooper ME, Touyz RM, Kennedy CR, Jandeleit-Dahm K. | 07/30/2022 |
| NOX5 mediates the crosstalk between tumor cells and cancer-associated fibroblasts via regulating cytokine network. | NOX5 mediates the crosstalk between tumor cells and cancer-associated fibroblasts via regulating cytokine network.
Chen J, Wang Y, Zhang W, Zhao D, Zhang L, Zhang J, Fan J, Zhan Q., Free PMC Article | 02/19/2022 |
| NADPH oxidase 5 has a crucial role in cellular motility of colon cancer cells. | NADPH oxidase 5 has a crucial role in cellular motility of colon cancer cells.
Ashizawa N, Shimizu H, Shoda K, Furuya S, Akaike H, Hosomura N, Kawaguchi Y, Amemiya H, Kawaida H, Sudo M, Inoue S, Kono H, Katsurahara K, Shiozaki A, Ichikawa D. | 12/11/2021 |
| Membranous NOX5-derived ROS oxidizes and activates local Src to promote malignancy of tumor cells. | Membranous NOX5-derived ROS oxidizes and activates local Src to promote malignancy of tumor cells.
Chen J, Wang Y, Zhang W, Zhao D, Zhang L, Fan J, Li J, Zhan Q., Free PMC Article | 10/9/2021 |
| Implications of NADPH oxidase 5 in vascular diseases. | Implications of NADPH oxidase 5 in vascular diseases.
Marqués J, Cortés A, Pejenaute Á, Zalba G. | 08/21/2021 |
| Epoxyazadiradione exhibit activities in head and neck squamous cell carcinoma by targeting multiple pathways. | Epoxyazadiradione exhibit activities in head and neck squamous cell carcinoma by targeting multiple pathways.
Rai V, Aggarwal SK, Verma SS, Awasthee N, Dhasmana A, Aggarwal S, Das SN, Nair MS, Yadav S, Gupta SC. | 07/31/2021 |
| NOX5 is expressed aberrantly but not a critical pathogenetic gene in Hirschsprung disease. | NOX5 is expressed aberrantly but not a critical pathogenetic gene in Hirschsprung disease.
Wang J, Xiao J, Meng X, Chu X, Zhuansun DD, Xiong B, Feng J., Free PMC Article | 07/10/2021 |
| Beta-Cell-Specific Expression of Nicotinamide Adenine Dinucleotide Phosphate Oxidase 5 Aggravates High-Fat Diet-Induced Impairment of Islet Insulin Secretion in Mice. | Beta-Cell-Specific Expression of Nicotinamide Adenine Dinucleotide Phosphate Oxidase 5 Aggravates High-Fat Diet-Induced Impairment of Islet Insulin Secretion in Mice.
Bouzakri K, Veyrat-Durebex C, Holterman C, Arous C, Barbieux C, Bosco D, Altirriba J, Alibashe M, Tournier BB, Gunton JE, Mouche S, Bietiger W, Forterre A, Berney T, Pinget M, Christofori G, Kennedy C, Szanto I. | 07/3/2021 |
| Reactive Oxygen-Forming Nox5 Links Vascular Smooth Muscle Cell Phenotypic Switching and Extracellular Vesicle-Mediated Vascular Calcification. | Reactive Oxygen-Forming Nox5 Links Vascular Smooth Muscle Cell Phenotypic Switching and Extracellular Vesicle-Mediated Vascular Calcification.
Furmanik M, Chatrou M, van Gorp R, Akbulut A, Willems B, Schmidt H, van Eys G, Bochaton-Piallat ML, Proudfoot D, Biessen E, Hedin U, Perisic L, Mees B, Shanahan C, Reutelingsperger C, Schurgers L. | 05/29/2021 |
| On the mechanism of calcium-dependent activation of NADPH oxidase 5 (NOX5). | On the mechanism of calcium-dependent activation of NADPH oxidase 5 (NOX5).
Millana Fañanás E, Todesca S, Sicorello A, Masino L, Pompach P, Magnani F, Pastore A, Mattevi A., Free PMC Article | 05/1/2021 |
| Induction of Cyclooxygenase-2 by Overexpression of the Human NADPH Oxidase 5 (NOX5) Gene in Aortic Endothelial Cells. | Induction of Cyclooxygenase-2 by Overexpression of the Human NADPH Oxidase 5 (NOX5) Gene in Aortic Endothelial Cells.
Marqués J, Cortés A, Pejenaute Á, Ansorena E, Abizanda G, Prósper F, Martínez-Irujo JJ, Miguel C, Zalba G., Free PMC Article | 03/13/2021 |
| Inhibition of NADPH Oxidase 5 (NOX5) Suppresses High Glucose-Induced Oxidative Stress, Inflammation and Extracellular Matrix Accumulation in Human Glomerular Mesangial Cells. | Inhibition of NADPH Oxidase 5 (NOX5) Suppresses High Glucose-Induced Oxidative Stress, Inflammation and Extracellular Matrix Accumulation in Human Glomerular Mesangial Cells.
Li Y, Li Y, Zheng S., Free PMC Article | 11/28/2020 |
| These results provide new insights into the involvement of the miR-485-NOX5 signaling pathway in diabetic nephtopathy progression. | miR-485 suppresses inflammation and proliferation of mesangial cells in an in vitro model of diabetic nephropathy by targeting NOX5.
Wu J, Lu K, Zhu M, Xie X, Ding Y, Shao X, Chen Y, Liu J, Xu M, Xu Y, Zhou J, Shen X, Zhu C. | 08/1/2020 |
| This review provides a comprehensive overview of our current understanding of NOX5, from basic biology to human disease, and highlights the unique characteristics of this enigmatic Nox isoform-{REVIEW} | NOX5: Molecular biology and pathophysiology.
Touyz RM, Anagnostopoulou A, Rios F, Montezano AC, Camargo LL., Free PMC Article | 07/25/2020 |
| Nox5 is p22phox independent and producesO2 - in a constitutive and inducible manner. Although growing evidence indicates a role for Nox-derived ROS in cardiovascular (patho)physiology, the exact function of Nox5 remains unclear. However, a genome-wide association study identified Nox5 as a novel blood pressure-associated gene. [review] | Vascular Biology of Superoxide-Generating NADPH Oxidase 5-Implications in Hypertension and Cardiovascular Disease.
Touyz RM, Anagnostopoulou A, Camargo LL, Rios FJ, Montezano AC., Free PMC Article | 06/20/2020 |
| The histone acetyltransferase system is altered in human atherosclerosis. Under inflammatory conditions, HAT subtypes control Nox5 overexpression in cultured human macrophages. The data suggest the existence of a new epigenetic mechanism underlying oxidative stress in atherosclerosis. | Histone Acetyltransferase-Dependent Pathways Mediate Upregulation of NADPH Oxidase 5 in Human Macrophages under Inflammatory Conditions: A Potential Mechanism of Reactive Oxygen Species Overproduction in Atherosclerosis.
Vlad ML, Manea SA, Lazar AG, Raicu M, Muresian H, Simionescu M, Manea A., Free PMC Article | 03/21/2020 |
| The overexpression of NOX5 protein may induce excessive ROS production and oxidative stress damages to DNA and plasma membrane integrity in asthenozoospermic men. | Evaluation of the NOX5 protein expression and oxidative stress in sperm from asthenozoospermic men compared to normozoospermic men.
Vatannejad A, Tavilani H, Sadeghi MR, Karimi M, Lakpour N, Amanpour S, Shabani Nashtaei M, Doosti M. | 02/8/2020 |
| Studied the association of NADPH oxidase 5 (NOX5) single nucleotide polymorphisms with Hirschsprung disease risk. | Association analysis of NOX5 polymorphisms with Hirschsprung disease.
Shin JG, Seo JY, Seo JM, Kim DY, Oh JT, Park KW, Kim HY, Kim JH, Shin HD. | 12/14/2019 |