| Collectin-11 promotes cancer cell proliferation and tumor growth. | Collectin-11 promotes cancer cell proliferation and tumor growth.
Wang JX, Cao B, Ma N, Wu KY, Chen WB, Wu W, Dong X, Liu CF, Gao YF, Diao TY, Min XY, Yong Q, Li ZF, Zhou W, Li K., Free PMC Article | 03/10/2023 |
| Collectin11 and Complement Activation in IgA Nephropathy. | Collectin11 and Complement Activation in IgA Nephropathy.
Wei M, Guo WY, Xu BY, Shi SF, Liu LJ, Zhou XJ, Lv JC, Zhu L, Zhang H., Free PMC Article | 01/21/2023 |
| Importance of glycosylation in the interaction of Tamm-Horsfall protein with collectin-11 and acute kidney injury. | Importance of glycosylation in the interaction of Tamm-Horsfall protein with collectin-11 and acute kidney injury.
Gong K, Xia M, Wang Y, Bai L, Ying W, Zhu F, Chen Y., Free PMC Article | 09/11/2021 |
| Association of Polymorphisms of MASP1/3, COLEC10, and COLEC11 Genes with 3MC Syndrome. | Association of Polymorphisms of MASP1/3, COLEC10, and COLEC11 Genes with 3MC Syndrome.
Gajek G, Świerzko AS, Cedzyński M., Free PMC Article | 04/17/2021 |
| C1q/TNF-Related Protein 6 Is a Pattern Recognition Molecule That Recruits Collectin-11 from the Complement System to Ligands. | C1q/TNF-Related Protein 6 Is a Pattern Recognition Molecule That Recruits Collectin-11 from the Complement System to Ligands.
Kirketerp-Møller N, Bayarri-Olmos R, Krogfelt KA, Garred P. | 11/21/2020 |
| this review discuss the role of collectin-11 as a pattern recognition molecule in complement-mediated ischemic kidney injury | Collectin-11 (CL-11) Is a Major Sentinel at Epithelial Surfaces and Key Pattern Recognition Molecule in Complement-Mediated Ischaemic Injury.
Nauser CL, Howard MC, Fanelli G, Farrar CA, Sacks S., Free PMC Article | 10/5/2019 |
| The allele rs7567833G, the genotypes rs7567833AG and rs7567833GG, and the COLEC11*GGC haplotype were related to T. cruzi infection and clinical progression towards symptomatic Chagas Disease (CD). COLEC11 and MASP2*CD risk genotypes were associated with cardiomyopathy, suggesting that both loci act synergistically in immune modulation of the disease. | Human collectin-11 (COLEC11) and its synergic genetic interaction with MASP2 are associated with the pathophysiology of Chagas Disease.
Sandri TL, Andrade FA, Lidani KCF, Einig E, Boldt ABW, Mordmüller B, Esen M, Messias-Reason IJ., Free PMC Article | 09/21/2019 |
| Collectin liver 1 (CL-L1, collectin 10) and collectin kidney 1 (CL-K1, collectin 11) were found widespread and almost identical tissue with a high expression in epithelial cells in endo-/exocrine secretory tissues and mucosa. | CL-L1 and CL-K1 Exhibit Widespread Tissue Distribution With High and Co-Localized Expression in Secretory Epithelia and Mucosa.
Hansen SWK, Aagaard JB, Bjerrum KB, Hejbøl EK, Nielsen O, Schrøder HD, Skjoedt K, Sørensen AL, Graversen JH, Henriksen ML., Free PMC Article | 09/14/2019 |
| this study demonstrates the role of CL-11 and the molecular mechanisms involved in modulating retinal pigment epithelial cell phagocytosis and cytokine production | Collectin-11 Is an Important Modulator of Retinal Pigment Epithelial Cell Phagocytosis and Cytokine Production.
Dong X, Wu W, Ma L, Liu C, Bhuckory MB, Wang L, Nandrot EF, Xu H, Li K, Liu Y, Zhou W., Free PMC Article | 07/28/2018 |
| High CLK1 expression is associated with cardiovascular disease. | Collectin Liver 1 and Collectin Kidney 1 of the Lectin Complement Pathway Are Associated With Mortality After Kidney Transplantation.
Smedbråten J, Sagedal S, Åsberg A, Hartmann A, Rollag H, Mjøen G, Fagerland MW, Hansen SW, Mollnes TE, Thiel S. | 12/16/2017 |
| The exclusion of the MASP1 and COLEC11 Loci in two individuals from different consanguineous families and the absence of mutations in four further individuals sequenced for both genes raises the possibility that that there is further genetic heterogeneity of 3MC syndrome | Exploring the genetic basis of 3MC syndrome: Findings in 12 further families.
Urquhart J, Roberts R, de Silva D, Shalev S, Chervinsky E, Nampoothiri S, Sznajer Y, Revencu N, Gunasekera R, Suri M, Ellingford J, Williams S, Bhaskar S, Clayton-Smith J. | 01/14/2017 |
| identify collectin CL-LK as a novel soluble C-type lectin able to bind M. tuberculosis, and characterize mycobacterial mannose-capped lipoarabinomannan as a primary ligand for CL-LK | Collectin CL-LK Is a Novel Soluble Pattern Recognition Receptor for Mycobacterium tuberculosis.
Troegeler A, Lugo-Villarino G, Hansen S, Rasolofo V, Henriksen ML, Mori K, Ohtani K, Duval C, Mercier I, Bénard A, Nigou J, Hudrisier D, Wakamiya N, Neyrolles O., Free PMC Article | 05/7/2016 |
| Data indicate differences in the plasma concentrations of collectin liver 1 and collectin kidney 1, M-ficolin and H-ficol in systemic lupus erythematosus (SLE) patients compared to a group of healthy controls. | Collectin liver 1 and collectin kidney 1 and other complement-associated pattern recognition molecules in systemic lupus erythematosus.
Troldborg A, Thiel S, Jensen L, Hansen S, Laska MJ, Deleuran B, Jensenius JC, Stengaard-Pedersen K., Free PMC Article | 03/19/2016 |
| promoter polymorphism COLEC11-9570C>T (rs3820897) was associated with decreased levels of CL-K1. | Genetic variation of COLEC10 and COLEC11 and association with serum levels of collectin liver 1 (CL-L1) and collectin kidney 1 (CL-K1).
Bayarri-Olmos R, Hansen S, Henriksen ML, Storm L, Thiel S, Garred P, Munthe-Fog L., Free PMC Article | 01/16/2016 |
| the sugar specificity of CL-K1 was established. | Molecular basis of sugar recognition by collectin-K1 and the effects of mutations associated with 3MC syndrome.
Venkatraman Girija U, Furze CM, Gingras AR, Yoshizaki T, Ohtani K, Marshall JE, Wallis AK, Schwaeble WJ, El-Mezgueldi M, Mitchell DA, Moody PC, Wakamiya N, Wallis R., Free PMC Article | 09/26/2015 |
| These results suggest that specific diseases may affect CL-K1 synthesis in an organ dependent manner and that elevated plasma CL-K1 levels are associated with the presence of DIC. | Elevated plasma CL-K1 level is associated with a risk of developing disseminated intravascular coagulation (DIC).
Takahashi K, Ohtani K, Larvie M, Moyo P, Chigweshe L, Van Cott EM, Wakamiya N., Free PMC Article | 05/16/2015 |
| Most plasma CL-K1 was found in complex with CL-L1 in a ratio suggesting a heteromeric subunit of 1 CL-L1 & 2 CL-K1 polypeptides. It associated with MASPs 1, 2 & 3. On binding mannan or DNA in the presence of MASP-2, the complex deposited C4b. | Heteromeric complexes of native collectin kidney 1 and collectin liver 1 are found in the circulation with MASPs and activate the complement system.
Henriksen ML, Brandt J, Andrieu JP, Nielsen C, Jensen PH, Holmskov U, Jorgensen TJ, Palarasah Y, Thielens NM, Hansen S. | 02/22/2014 |
| Data suggest that collectin 11 (CL-11), e.g. via complement, may play a role in response to particles and surfaces presenting extracellular DNA, such as apopototic cells. | Characterization of the interaction between collectin 11 (CL-11, CL-K1) and nucleic acids.
Henriksen ML, Brandt J, Iyer SS, Thielens NM, Hansen S. | 12/21/2013 |
| collectin-11 associates with all the known MBL-associated serine proteases (MASP-1, MASP-2 and MASP-3) as well as the lectin complement pathway regulator MAP-1. | Collectin-11/MASP complex formation triggers activation of the lectin complement pathway--the fifth lectin pathway initiation complex.
Ma YJ, Skjoedt MO, Garred P., Free PMC Article | 11/16/2013 |
| Data show that the concentration of collectin kidney 1 (CL-K1, COLEC11) in plasma was 0.34 +/- 0.13 microg/ml and that in mannan-binding lectin (MBL) was 1.72 +/- 1.51 microg/ml. | Comparison of human blood concentrations of collectin kidney 1 and mannan-binding lectin.
Yoshizaki T, Ohtani K, Motomura W, Jang SJ, Mori K, Kitamoto N, Yoshida I, Suzuki Y, Wakamiya N. | 05/19/2012 |
| these findings demonstrate a role for complement pathway factors in fundamental developmental processes and in the etiology of 3MC syndrome. | Mutations in lectin complement pathway genes COLEC11 and MASP1 cause 3MC syndrome.
Rooryck C, Diaz-Font A, Osborn DP, Chabchoub E, Hernandez-Hernandez V, Shamseldin H, Kenny J, Waters A, Jenkins D, Kaissi AA, Leal GF, Dallapiccola B, Carnevale F, Bitner-Glindzicz M, Lees M, Hennekam R, Stanier P, Burns AJ, Peeters H, Alkuraya FS, Beales PL., Free PMC Article | 04/23/2011 |
| CL-11 plays a role in activation of the complement system and in the defense against invading microorganisms | Collectin 11 (CL-11, CL-K1) is a MASP-1/3-associated plasma collectin with microbial-binding activity.
Hansen S, Selman L, Palaniyar N, Ziegler K, Brandt J, Kliem A, Jonasson M, Skjoedt MO, Nielsen O, Hartshorn K, Jørgensen TJ, Skjødt K, Holmskov U. | 12/4/2010 |
| Observational study of gene-disease association. (HuGE Navigator) | See all PubMed (4) articlesNew genetic associations detected in a host response study to hepatitis B vaccine.
Davila S, Froeling FE, Tan A, Bonnard C, Boland GJ, Snippe H, Hibberd ML, Seielstad M. Association of genetic variants with hemorrhagic stroke in Japanese individuals.
Yoshida T, Kato K, Yokoi K, Oguri M, Watanabe S, Metoki N, Yoshida H, Satoh K, Aoyagi Y, Nozawa Y, Yamada Y. Assessment of a polymorphism of SDK1 with hypertension in Japanese Individuals.
Oguri M, Kato K, Yokoi K, Yoshida T, Watanabe S, Metoki N, Yoshida H, Satoh K, Aoyagi Y, Nozawa Y, Yamada Y. Association of gene polymorphisms with chronic kidney disease in Japanese individuals.
Yoshida T, Kato K, Yokoi K, Oguri M, Watanabe S, Metoki N, Yoshida H, Satoh K, Aoyagi Y, Nozawa Y, Yamada Y. | 12/2/2009 |