| Zinc transporter 1 functions in copper uptake and cuproptosis. | Zinc transporter 1 functions in copper uptake and cuproptosis.
Li Y, Ma J, Wang R, Luo Y, Zheng S, Wang X. | 09/12/2024 |
| Structural insights into the calcium-coupled zinc export of human ZnT1. | Structural insights into the calcium-coupled zinc export of human ZnT1.
Sun C, He B, Gao Y, Wang X, Liu X, Sun L., Free PMC Article | 04/30/2024 |
| Zinc transporter 1 expression in hepatocellular carcinoma correlates with prognosis: A single-center retrospective study. | Zinc transporter 1 expression in hepatocellular carcinoma correlates with prognosis: A single-center retrospective study.
Kakita N, Katayama K, Yasui T, Satake S, Aoi K, Jo H, Kim YK, Yamazaki M, Hashimoto A, Kambe T. | 01/12/2024 |
| Somatic SLC30A1 mutations altering zinc transporter ZnT1 cause aldosterone-producing adenomas and primary aldosteronism. | Somatic SLC30A1 mutations altering zinc transporter ZnT1 cause aldosterone-producing adenomas and primary aldosteronism.
Rege J, Bandulik S, Nanba K, Kosmann C, Blinder AR, Plain A, Vats P, Kumar-Sinha C, Lerario AM, Else T, Yamazaki Y, Satoh F, Sasano H, Giordano TJ, Williams TA, Reincke M, Turcu AF, Udager AM, Warth R, Rainey WE. | 10/11/2023 |
| The Roles of ZnT1 and ZnT4 in Glucose-Stimulated Zinc Secretion in Prostate Epithelial Cells. | The Roles of ZnT1 and ZnT4 in Glucose-Stimulated Zinc Secretion in Prostate Epithelial Cells.
Lo ST, Parrott D, Jordan MVC, Joseph DB, Strand D, Lo UG, Lin H, Darehshouri A, Sherry AD., Free PMC Article | 11/13/2021 |
| Increased expression of zinc transporter ZIP4, ZIP11, ZnT1, and ZnT6 predicts poor prognosis in pancreatic cancer. | Increased expression of zinc transporter ZIP4, ZIP11, ZnT1, and ZnT6 predicts poor prognosis in pancreatic cancer.
Zhu B, Huo R, Zhi Q, Zhan M, Chen X, Hua ZC. | 10/16/2021 |
| Frontline Science: LPS-inducible SLC30A1 drives human macrophage-mediated zinc toxicity against intracellular Escherichia coli. | Frontline Science: LPS-inducible SLC30A1 drives human macrophage-mediated zinc toxicity against intracellular Escherichia coli.
Stocks CJ, von Pein JB, Curson JEB, Rae J, Phan MD, Foo D, Bokil NJ, Kambe T, Peters KM, Parton RG, Schembri MA, Kapetanovic R, Sweet MJ., Free PMC Article | 03/20/2021 |
| MiRNA-8073 targets ZnT1 to inhibit malignant progression of ovarian cancer. | MiRNA-8073 targets ZnT1 to inhibit malignant progression of ovarian cancer.
Zhang L, Wang YH, Wang L. | 10/3/2020 |
| SRB1 in macrophages regulates phagocytosis and promotes M1 switch into M2 macrophages, contributing to muscle regeneration. | Zinc transporter 1 (ZNT1) expression on the cell surface is elaborately controlled by cellular zinc levels.
Nishito Y, Kambe T., Free PMC Article | 06/6/2020 |
| This study showed that there was a significant increase in protein levels of ZnT1 in the prefrontal cortex in Major depressive disorder, relative to control subjects | Zinc transporters protein level in postmortem brain of depressed subjects and suicide victims.
Rafalo-Ulinska A, Piotrowska J, Kryczyk A, Opoka W, Sowa-Kucma M, Misztak P, Rajkowska G, Stockmeier CA, Datka W, Nowak G, Szewczyk B., Free PMC Article | 09/23/2017 |
| MTF1 heads a hierarchy of zinc sensors, and through controlling the expression of a raft of metallothioneins and other key proteins involved in controlling intracellular zinc levels (e.g. ZnT1) alters zinc buffering capacity and total cellular zinc content. | Zinc sensing by metal-responsive transcription factor 1 (MTF1) controls metallothionein and ZnT1 expression to buffer the sensitivity of the transcriptome response to zinc.
Hardyman JE, Tyson J, Jackson KA, Aldridge C, Cockell SJ, Wakeling LA, Valentine RA, Ford D. | 12/17/2016 |
| Data indicate that zinc transporters ZnT1 and Zip1 were the most abundantly expressed zinc transporters in leukocytes. | The alteration of zinc transporter gene expression is associated with inflammatory markers in obese women.
Noh H, Paik HY, Kim J, Chung J. | 05/16/2015 |
| ZnT-1 extrudes zinc from mammalian cells by functioning as a Zn(2+)/H(+) exchanger. | ZnT-1 extrudes zinc from mammalian cells functioning as a Zn(2+)/H(+) exchanger.
Shusterman E, Beharier O, Shiri L, Zarivach R, Etzion Y, Campbell CR, Lee IH, Okabayashi K, Dinudom A, Cook DI, Katz A, Moran A. | 04/25/2015 |
| Data indicate that the expression levels of ZnT and ZIP families in the three cell lines, when treated with high concentration of ZnSO4, increased and decreased corresponding to their functions, respectively. | Effects of exogenous zinc on cell cycle, apoptosis and viability of MDAMB231, HepG2 and 293 T cells.
Wang YH, Li KJ, Mao L, Hu X, Zhao WJ, Hu A, Lian HZ, Zheng WJ. | 03/15/2014 |
| ZnT-1 augments CaV3.1 and CaV3.2 channel signals by stimulating the Ras-ERK pathways. | ZnT-1 enhances the activity and surface expression of T-type calcium channels through activation of Ras-ERK signaling.
Mor M, Beharier O, Levy S, Kahn J, Dror S, Blumenthal D, Gheber LA, Peretz A, Katz A, Moran A, Etzion Y. | 10/6/2012 |
| The results of this study showed that signi fi cant positive correlations between ZIP1,ZnT1, and ZnT6 in most brain in patient with Alzheimer's disease. | Zinc transporter mRNA levels in Alzheimer's disease postmortem brain.
Beyer N, Coulson DT, Heggarty S, Ravid R, Hellemans J, Irvine GB, Johnston JA. | 08/18/2012 |
| The metallothionein gene had a higher expression in the blood, when compared to zinc transporters ZnT-1, Zip-1, and Zip-3 (p=0.01 in obese patients. | Expression of the zinc transporters genes and metallothionein in obese women.
dos Santos Rocha PB, de Castro Amorim A, de Sousa AF, do Monte SJ, da Mata Sousa LC, do Nascimento Nogueira N, Neto JM, do Nascimento Marreiro D. | 04/14/2012 |
| Differentiated Caco-2 cells tolerate significantly higher levels of zinc compared to undifferentiated Caco-2 cells, which was accompanied by upregulated ZnT-1 and downregulated ZIP1 levels. | Differentiation- and polarization-dependent zinc tolerance in Caco-2 cells.
Zemann N, Zemann A, Klein P, Elmadfa I, Huettinger M. | 12/24/2011 |
| the transporter ZnT1 at the basolateral membrane, regulate the amount of zinc released to the portal circulation for systemic distribution | Gastrointestinal factors influencing zinc absorption and homeostasis.
Cousins RJ., Free PMC Article | 06/18/2011 |
| GSPE and EGCG inhibit the expression of zinc-binding metallothioneins and plasma membrane zinc exporter ZnT1 (SLC30A1). | Dietary catechins and procyanidins modulate zinc homeostasis in human HepG2 cells.
Quesada IM, Bustos M, Blay M, Pujadas G, Ardèvol A, Salvadó MJ, Bladé C, Arola L, Fernández-Larrea J. | 04/30/2011 |
| our results suggest that alterations in Zn transport proteins ZnT-1, ZnT-4 and ZnT-6 may contribute to the pathology observed in preclinical Alzheimer's disease subjects before onset of clinical symptoms | Alterations of zinc transporter proteins ZnT-1, ZnT-4 and ZnT-6 in preclinical Alzheimer's disease brain.
Lyubartseva G, Smith JL, Markesbery WR, Lovell MA., Free PMC Article | 08/16/2010 |
| The effects of zinc and cadmium on the expression and membrane localization of metallothioneins and ZNT1 in hepatoma cells are reproted. | Regulation of metallothioneins and ZnT-1 transporter expression in human hepatoma cells HepG2 exposed to zinc and cadmium.
Urani C, Melchioretto P, Gribaldo L. | 06/14/2010 |
| ZnT-1 expression was found to be augmented in the atria of atrial tachycardia patients. | The involvement of ZnT-1, a new modulator of cardiac L-type calcium channels, in [corrected] atrial tachycardia remodeling. [corrected].
Beharier O, Etzion Y, Levi S, Mor M, Mor M, Dror S, Kahn J, Katz A, Moran A. | 04/19/2010 |
| Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator) | Polymorphisms in innate immunity genes and lung cancer risk in Xuanwei, China.
Shen M, Vermeulen R, Rajaraman P, Menashe I, He X, Chapman RS, Yeager M, Thomas G, Burdett L, Hutchinson A, Yuenger J, Chanock S, Lan Q., Free PMC Article | 04/7/2010 |
| zinc transporter 1 is an endogenous inhibitor of L-type calcium channels | Molecular basis for zinc transporter 1 action as an endogenous inhibitor of L-type calcium channels.
Levy S, Beharier O, Etzion Y, Mor M, Buzaglo L, Shaltiel L, Gheber LA, Kahn J, Muslin AJ, Katz A, Gitler D, Moran A., Free PMC Article | 01/21/2010 |