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    Rab35 RAB35, member RAS oncogene family [ Mus musculus (house mouse) ]

    Gene ID: 77407, updated on 27-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    RAB35 is required for murine hippocampal development and functions by regulating neuronal cell distribution.

    RAB35 is required for murine hippocampal development and functions by regulating neuronal cell distribution.
    Maejima I, Hara T, Tsukamoto S, Koizumi H, Kawauchi T, Akuzawa T, Hirai R, Kobayashi H, Isobe I, Emoto K, Kosako H, Sato K., Free PMC Article

    04/26/2023
    miR-720 Regulates Insulin Secretion by Targeting Rab35.

    miR-720 Regulates Insulin Secretion by Targeting Rab35.
    Lu C, Wang D, Feng Y, Feng L, Li Z., Free PMC Article

    05/29/2021
    Rab35 and its effectors promote formation of tunneling nanotubes in neuronal cells.

    Rab35 and its effectors promote formation of tunneling nanotubes in neuronal cells.
    Bhat S, Ljubojevic N, Zhu S, Fukuda M, Echard A, Zurzolo C., Free PMC Article

    01/9/2021
    Rab35-regulated lipid turnover by myotubularins represses mTORC1 activity and controls myelin growth.

    Rab35-regulated lipid turnover by myotubularins represses mTORC1 activity and controls myelin growth.
    Sawade L, Grandi F, Mignanelli M, Patiño-López G, Klinkert K, Langa-Vives F, Di Guardo R, Echard A, Bolino A, Haucke V., Free PMC Article

    08/22/2020
    Results suggest that RAB35 GTPase has multiple roles in spindle stability and actin-mediated spindle migration in mouse oocyte meiosis.

    RAB35 depletion affects spindle formation and actin-based spindle migration in mouse oocyte meiosis.
    Zhang Y, Wan X, Wang HH, Pan MH, Pan ZN, Sun SC.

    07/4/2020
    These findings demonstrate roles for Rab35 in regulating cilium length.

    Rab35 controls cilium length, function and membrane composition.
    Kuhns S, Seixas C, Pestana S, Tavares B, Nogueira R, Jacinto R, Ramalho JS, Simpson JC, Andersen JS, Echard A, Lopes SS, Barral DC, Blacque OE., Free PMC Article

    05/16/2020
    A RAB35-p85/PI3K axis controls oscillatory apical protrusions required for efficient chemotactic migration.

    A RAB35-p85/PI3K axis controls oscillatory apical protrusions required for efficient chemotactic migration.
    Corallino S, Malinverno C, Neumann B, Tischer C, Palamidessi A, Frittoli E, Panagiotakopoulou M, Disanza A, Malet-Engra G, Nastaly P, Galli C, Luise C, Bertalot G, Pece S, Di Fiore PP, Gauthier N, Ferrari A, Maiuri P, Scita G., Free PMC Article

    12/22/2018
    This study demonstrated that Rab35 regulates Cdc42 activity in neurons.

    Rab35 Functions in Axon Elongation Are Regulated by P53-Related Protein Kinase in a Mechanism That Involves Rab35 Protein Degradation and the Microtubule-Associated Protein 1B.
    Villarroel-Campos D, Henríquez DR, Bodaleo FJ, Oguchi ME, Bronfman FC, Fukuda M, Gonzalez-Billault C., Free PMC Article

    07/22/2017
    The Rab35 plays an important role in spindle organization and morphology maintenance, and thus meiotic nuclear maturation.

    Rab3A, Rab27A, and Rab35 regulate different events during mouse oocyte meiotic maturation and activation.
    Wang HH, Cui Q, Zhang T, Wang ZB, Ouyang YC, Shen W, Ma JY, Schatten H, Sun QY.

    04/8/2017
    Rab35 regulates myoblast fusion, a major cellular process under the control of cadherin-dependent signaling.

    Rab35 regulates cadherin-mediated adherens junction formation and myoblast fusion.
    Charrasse S, Comunale F, De Rossi S, Echard A, Gauthier-Rouvière C., Free PMC Article

    07/27/2013
    Rab35 regulates phagosome formation through recruitment of ACAP2 in macrophages during FcgammaR-mediated phagocytosis.

    Rab35 regulates phagosome formation through recruitment of ACAP2 in macrophages during FcγR-mediated phagocytosis.
    Egami Y, Fukuda M, Araki N.

    03/31/2012
    The minimal functional Rab35-binding site of RUSC2 was identified at the amino acid residues 982-1199 and succeeded in developing a novel GTP-Rab35-specific trapper.

    Genome-wide investigation of the Rab binding activity of RUN domains: development of a novel tool that specifically traps GTP-Rab35.
    Fukuda M, Kobayashi H, Ishibashi K, Ohbayashi N.

    12/31/2011
    study found that Rab35 regulates the assembly of actin filaments in filopodia formation; effect was mediated by the actin-bundling protein fascin, which directly associated with active Rab35

    Rab35 controls actin bundling by recruiting fascin as an effector protein.
    Zhang J, Fonovic M, Suyama K, Bogyo M, Scott MP.

    01/21/2010
    Rab35 colocalizes with actin filaments and with Cdc42, Rac1 and RhoA, and that Rab35 can activate Cdc42 both in vivo and in vitro

    Rab35 regulates neurite outgrowth and cell shape.
    Chevallier J, Koop C, Srivastava A, Petrie RJ, Lamarche-Vane N, Presley JF.

    01/21/2010
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