| Long non-coding RNA X-Inactive Specific Transcript (XIST) interacting with USF2 promotes osteogenic differentiation of periodontal ligament stem cells through regulation of WDR72 transcription. | Long non-coding RNA X-Inactive Specific Transcript (XIST) interacting with USF2 promotes osteogenic differentiation of periodontal ligament stem cells through regulation of WDR72 transcription.
Xu K, Li YD, Ren LY, Song HL, Yang QY, Xu DL. | 11/20/2023 |
| WDR3 promotes stem cell-like properties in prostate cancer by inhibiting USF2-mediated transcription of RASSF1A. | WDR3 promotes stem cell-like properties in prostate cancer by inhibiting USF2-mediated transcription of RASSF1A.
Liu W, Xie A, Xiong J, Li S, Yang L, Liu W. | 07/19/2023 |
| USF2-mediated upregulation of TXNRD1 contributes to hepatocellular carcinoma progression by activating Akt/mTOR signaling. | USF2-mediated upregulation of TXNRD1 contributes to hepatocellular carcinoma progression by activating Akt/mTOR signaling.
Huang WY, Liao ZB, Zhang JC, Zhang X, Zhang HW, Liang HF, Zhang ZY, Yang T, Yu J, Dong KS., Free PMC Article | 11/5/2022 |
| Upstream stimulatory factor 2 inhibits erastin-induced ferroptosis in pancreatic cancer through transcriptional regulation of pyruvate kinase M2. | Upstream stimulatory factor 2 inhibits erastin-induced ferroptosis in pancreatic cancer through transcriptional regulation of pyruvate kinase M2.
Chen M, Li X, Du B, Chen S, Li Y. | 10/29/2022 |
| USF2 knockdown downregulates THBS1 to inhibit the TGF-beta signaling pathway and reduce pyroptosis in sepsis-induced acute kidney injury. | USF2 knockdown downregulates THBS1 to inhibit the TGF-β signaling pathway and reduce pyroptosis in sepsis-induced acute kidney injury.
Sun J, Ge X, Wang Y, Niu L, Tang L, Pan S. | 03/26/2022 |
| USF2 reduces BMP3 expression via transcriptional activation of miR-34a, thus promoting osteogenic differentiation of BMSCs. | USF2 reduces BMP3 expression via transcriptional activation of miR-34a, thus promoting osteogenic differentiation of BMSCs.
Zeng HB, Dong LQ, Huang YL, Xu C, Zhao XH, Wu LG. | 12/18/2021 |
| Functional interrogation of HOXA9 regulome in MLLr leukemia via reporter-based CRISPR/Cas9 screen. | Functional interrogation of HOXA9 regulome in MLLr leukemia via reporter-based CRISPR/Cas9 screen.
Zhang H, Zhang Y, Zhou X, Wright S, Hyle J, Zhao L, An J, Zhao X, Shao Y, Xu B, Lee HM, Chen T, Zhou Y, Chen X, Lu R, Li C., Free PMC Article | 05/15/2021 |
| Irrelevance of USF2 rs916145 polymorphism with the risk of biliary atresia susceptibility in Southern Chinese children. | Irrelevance of USF2 rs916145 polymorphism with the risk of biliary atresia susceptibility in Southern Chinese children.
Chen L, Fu M, Tan L, Zhao J, Xu X, Lin Y, Zhong Q, Zhong R, Zhang R, Zeng J., Free PMC Article | 03/20/2021 |
| USF2 and ATF4 were upregulated in the osteogenic differentiation of periodontal ligament cells | USF2 enhances the osteogenic differentiation of PDLCs by promoting ATF4 transcriptional activities.
Liu F, Wang X, Zheng B, Li D, Chen C, Lee IS, Zhong J, Li D, Liu Y. | 03/7/2020 |
| This study reported that USF2 (upstream stimulatory factor 2), a basic helix-loop-helix-leucine-zip transcription factor, is necessary for the transcriptional activity of Smurf1 and Smurf2. | USF2 inhibits the transcriptional activity of Smurf1 and Smurf2 to promote breast cancer tumorigenesis.
Tan Y, Chen Y, Du M, Peng Z, Xie P. | 02/29/2020 |
| PLAG1 and USF2 cooperation is thus an important contributor to stem cell-specific expression of MSI2 and hematopoietic stem and progenitor cell-specific transcriptional circuitry. | PLAG1 and USF2 Co-regulate Expression of Musashi-2 in Human Hematopoietic Stem and Progenitor Cells.
Belew MS, Bhatia S, Keyvani Chahi A, Rentas S, Draper JS, Hope KJ., Free PMC Article | 04/27/2019 |
| TCF21 modulates Steroidogenic factor-1 and estrogen receptor beta expression through the recruitment of USF2 in endometriotic stromal cells. | Transcription factor 21 regulates expression of ERβ and SF-1 via upstream stimulatory factor-2 in endometriotic tissues.
Wu PL, Zhou Y, Zeng C, Li X, Dong ZT, Zhou YF, Bulun SE, Xue Q. | 10/6/2018 |
| USF2, and its target gene PAI-1, regulate serum-stimulated keratinocyte growth, and likely the cadence of cell cycle progression in replicatively competent cells as part of the injury repair program. | The basic helix-loop-helix/leucine zipper transcription factor USF2 integrates serum-induced PAI-1 expression and keratinocyte growth.
Qi L, Higgins CE, Higgins SP, Law BK, Simone TM, Higgins PJ., Free PMC Article | 05/16/2015 |
| Increased upstream stimulatory factor in HCC is associated with heparanase expression. USF might be an important factor in regulating HPSE expression and act as a novel marker of metastatic recurrence of HCC patients | Expressions of heparanase and upstream stimulatory factor in hepatocellular carcinoma.
Chen B, Chen XP, Wu MS, Cui W, Zhong M., Free PMC Article | 03/21/2015 |
| RNA Pol II on HIF1 or HIF2 target genes is primarily associated with HIF1alpha or HIF2alpha in a STAT3 or USF2 dependent manner | STAT3 or USF2 contributes to HIF target gene specificity.
Pawlus MR, Wang L, Murakami A, Dai G, Hu CJ., Free PMC Article | 06/21/2014 |
| USF2 functionally interacts with YY1 blocking its inhibitory activity, in favor of CEBPB transactivation. | Phosphorylated C/EBPβ influences a complex network involving YY1 and USF2 in lung epithelial cells.
Viart V, Varilh J, Lopez E, René C, Claustres M, Taulan-Cadars M., Free PMC Article | 09/21/2013 |
| USF2 and hypoxia-inducible factor 2alpha (HIF2alpha) cooperatively activate HIF2 target genes during hypoxia. | Upstream stimulatory factor 2 and hypoxia-inducible factor 2α (HIF2α) cooperatively activate HIF2 target genes during hypoxia.
Pawlus MR, Wang L, Ware K, Hu CJ., Free PMC Article | 01/5/2013 |
| Transcription factors upstream stimulatory factor 1 (USF-1) and USF-2 are indispensable for the transcription of RORgammaT in human lymphocytes. | Upstream stimulating factors regulate the expression of RORγT in human lymphocytes.
Ratajewski M, Walczak-Drzewiecka A, Salkowska A, Dastych J. | 12/8/2012 |
| Bone morphogenetic proteins and ID1 exerted an anti-apoptotic effect in mesangial cells by inhibition of USF2 transcriptional activity. | ID1 inhibits USF2 and blocks TGF-β-induced apoptosis in mesangial cells.
Sato AY, Antonioli E, Tambellini R, Campos AH. | 02/4/2012 |
| These data indicate that an E-box motif (RBE1) within the core promoter in the long terminal repeat of HIV-1 is a bona fide binding site for the RBF-2 transcription factor complex USF1, USF2, and TFII-I. | Identification and functional analysis of a second RBF-2 binding site within the HIV-1 promoter.
Dahabieh MS, Ooms M, Malcolm T, Simon V, Sadowski I., Free PMC Article | 10/22/2011 |
| data established that high glucose stimulated USF2 expression in HK-2 cells, at least in part, through angiotensin II-AT1-dependent activation of CREB, which can contribute to diabetic tubulointerstitial fibrosis | High glucose upregulates upstream stimulatory factor 2 in human renal proximal tubular cells through angiotensin II-dependent activation of CREB.
Visavadiya NP, Li Y, Wang S., Free PMC Article | 06/18/2011 |
| Usf2 mediates quercetin-induced suppression of PAI-1 gene expression in human endothelial cells | Upstream stimulatory factor-2 mediates quercetin-induced suppression of PAI-1 gene expression in human endothelial cells.
Olave NC, Grenett MH, Cadeiras M, Grenett HE, Higgins PJ., Free PMC Article | 02/5/2011 |
| This study demonstrated the involvement of USF1 and USF2 as molecular targets of Helicobacter pylori and the key role of DNA methylation in their regulation. | H. pylori-induced promoter hypermethylation downregulates USF1 and USF2 transcription factor gene expression.
Bussière FI, Michel V, Mémet S, Avé P, Vivas JR, Huerre M, Touati E. | 10/23/2010 |
| Ddata indicate that USF2 is one of the components of the FoxA1/androgen receptor transcriptional protein complex that contributes to the expression of androgen-regulated and prostate-specific genes. | Upstream stimulatory factor 2, a novel FoxA1-interacting protein, is involved in prostate-specific gene expression.
Sun Q, Yu X, Degraff DJ, Matusik RJ., Free PMC Article | 03/1/2010 |
| USF1 and USF2 regulate transcriptional activity of the FOXE1 promoter. | The variant rs1867277 in FOXE1 gene confers thyroid cancer susceptibility through the recruitment of USF1/USF2 transcription factors.
Landa I, Ruiz-Llorente S, Montero-Conde C, Inglada-Pérez L, Schiavi F, Leskelä S, Pita G, Milne R, Maravall J, Ramos I, Andía V, Rodríguez-Poyo P, Jara-Albarrán A, Meoro A, del Peso C, Arribas L, Iglesias P, Caballero J, Serrano J, Picó A, Pomares F, Giménez G, López-Mondéjar P, Castello R, Merante-Boschin I, Pelizzo MR, Mauricio D, Opocher G, Rodríguez-Antona C, González-Neira A, Matías-Guiu X, Santisteban P, Robledo M., Free PMC Article | 01/21/2010 |