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    TDRG1 testis development related 1 [ Homo sapiens (human) ]

    Gene ID: 732253, updated on 2-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Analysis of Correlation Between LncRNA TDRG1 Expression and its Prognosis in Cervical Carcinoma Tissues.

    Analysis of Correlation Between LncRNA TDRG1 Expression and its Prognosis in Cervical Carcinoma Tissues.
    El-Lateef AEA, El-Shemi AGA, Hassanein RAM, Iqbal MS, Albloshi SA.

    02/21/2024
    Long non-coding RNA TDRG1 aggravates lung cancer stemness by binding to Sox2 mRNA.

    Long non-coding RNA TDRG1 aggravates lung cancer stemness by binding to Sox2 mRNA.
    Lu Y, Cheng J, Mao Q, Wang Z, Wei Q.

    02/15/2023
    LncRNA TDRG1 promotes the metastasis of NSCLC cell through regulating miR-873-5p/ZEB1 axis.

    LncRNA TDRG1 promotes the metastasis of NSCLC cell through regulating miR-873-5p/ZEB1 axis.
    Hu X, Mu Y, Wang J, Zhao Y.

    02/11/2023
    The rs8506 TT Genotype in lincRNA-NR_024015 Contributes to the Risk of Sepsis in a Southern Chinese Child Population.

    The rs8506 TT Genotype in lincRNA-NR_024015 Contributes to the Risk of Sepsis in a Southern Chinese Child Population.
    Li J, Zhou H, Wei B, Che D, Xu Y, Pi L, Fu L, Hong J, Gu X., Free PMC Article

    08/13/2022
    Long Noncoding RNAs Testis Development Related Gene 1 Aggravates Transforming Growth Factor-beta1-Induced Fibrogenesis and Inflammatory Response of Cardiac Fibroblasts Via miR-605-3p/Tumor Necrosis Factor Receptor Superfamily-21 Axis.

    Long Noncoding RNAs Testis Development Related Gene 1 Aggravates Transforming Growth Factor-β1-Induced Fibrogenesis and Inflammatory Response of Cardiac Fibroblasts Via miR-605-3p/Tumor Necrosis Factor Receptor Superfamily-21 Axis.
    Cheng J, Tang Y, Cai X, Gong J.

    05/7/2022
    Long non-coding RNA TDRG1 facilitates cell proliferation, migration and invasion in breast cancer via targeting miR-214-5p/CLIC4 axis.

    Long non-coding RNA TDRG1 facilitates cell proliferation, migration and invasion in breast cancer via targeting miR-214-5p/CLIC4 axis.
    Lv Y, Dong K, Gao H., Free PMC Article

    01/1/2022
    Testis developmental related gene 1 (TDRG1) encodes a progressive motility-associated protein in human spermatozoa.

    Testis developmental related gene 1 (TDRG1) encodes a progressive motility-associated protein in human spermatozoa.
    Chen H, Tang L, Hong Q, Pan T, Weng S, Sun J, Wu Q, Zeng X, Tang Y, Luo T.

    06/5/2021
    LncRNA TDRG1 promotes the proliferation, migration, and invasion of cervical cancer cells by sponging miR-214-5p to target SOX4.

    LncRNA TDRG1 promotes the proliferation, migration, and invasion of cervical cancer cells by sponging miR-214-5p to target SOX4.
    Guo M, Lin B, Li G, Lin J, Jiang X.

    02/6/2021
    LncRNA TDRG1/miR-214-5p axis affects preeclampsia by modulating trophoblast cells.

    LncRNA TDRG1/miR-214-5p axis affects preeclampsia by modulating trophoblast cells.
    Gong F, Cheng H, Shi Y, Cui L, Jia G.

    01/9/2021
    LncRNA TDRG1 functions as an oncogene in cervical cancer through sponging miR-330-5p to modulate ELK1 expression.

    LncRNA TDRG1 functions as an oncogene in cervical cancer through sponging miR-330-5p to modulate ELK1 expression.
    Zhao H, Hu GM, Wang WL, Wang ZH, Fang Y, Liu YL.

    10/10/2020
    Testis developmental related gene 1 regulates the chemosensitivity of seminoma TCam-2 cells to cisplatin via autophagy.

    Testis developmental related gene 1 regulates the chemosensitivity of seminoma TCam-2 cells to cisplatin via autophagy.
    Peng D, Wei J, Gan Y, Yang J, Jiang X, Kitazawa R, Xiang Y, Dai Y, Tang Y., Free PMC Article

    09/12/2020
    The crucial function of TDRG1-miR-873-5p-HDGF axis in human gastric cancer.

    LncRNA TDRG1 promotes the aggressiveness of gastric carcinoma through regulating miR-873-5p/HDGF axis.
    Ma Y, Xu XL, Huang HG, Li YF, Li ZG.

    06/6/2020
    lncRNA TDRG1 may promote endometrial carcinoma cell proliferation and invasion by positively targeting VEGF-A and modulating relative genes.

    LncRNA TDRG1 enhances tumorigenicity in endometrial carcinoma by binding and targeting VEGF-A protein.
    Chen S, Wang LL, Sun KX, Liu Y, Guan X, Zong ZH, Zhao Y.

    12/22/2018
    LncRNA TDRG1 overexpression induced tumor development and RhoC expression.

    The role of the long non-coding RNA TDRG1 in epithelial ovarian carcinoma tumorigenesis and progression through miR-93/RhoC pathway.
    Chen S, Wang LL, Sun KX, Xiu YL, Zong ZH, Chen X, Zhao Y.

    11/24/2018
    Study demonstrates that lincRNA-NR_024015 is up-regulated in esophageal squamous cell carcinoma (ESCC) tumor, especially in advanced stage. Furthermore, the G to A variant of rs8506 in lincRNA-NR_024015 may disrupt the binding of hsa-miR-526b to the gene, up regulate the expression level of lincRNA-NR_024015, promote cell proliferation, and associated with increased risk of ESCC.

    A genetic polymorphism at miR-526b binding-site in the lincRNA-NR_024015 exon confers risk of esophageal squamous cell carcinoma in a population of North China.
    Han L, Liu S, Liang J, Guo Y, Shen S, Guo X, Dong Z, Guo W.

    09/9/2017
    The localization of TDRG1 in human normal spermatozoa implies its potential regulatory role in sperm motility.

    Expression and localization of testis developmental related gene 1 (TDRG1) in human spermatozoa.
    Chen H, Sun J, He Y, Zou Q, Wu Q, Tang Y.

    12/19/2015
    A robust association is established between the rs8506G>A polymorphism in the lincRNA-NR_024015 exon and the risk of non-cardia gastric cancer.

    The has-miR-526b binding-site rs8506G>a polymorphism in the lincRNA-NR_024015 exon identified by GWASs predispose to non-cardia gastric cancer risk.
    Fan QH, Yu R, Huang WX, Cui XX, Luo BH, Zhang LY., Free PMC Article

    09/18/2015
    TDRG1, a newly identified testis-specific gene, may play important roles in human spermatogenesis.

    Characterization of a novel human testis-specific gene: testis developmental related gene 1 (TDRG1).
    Jiang X, Li D, Yang J, Wen J, Chen H, Xiao X, Dai Y, Yang J, Tang Y.

    03/31/2012
    The significantly reduced expression of the TDRG1 protein in patients with seminoma or teratoma indicates that TDRG1 may be a candidate cancer suppressor gene.

    [Expression of human testis development related gene 1 in testicular cancer detected by tissue microarray].
    Chen HY, Wen JM, Xiao XW, Li DJ, Guo XL, Long Z, Dai YB, Tang YX.

    11/19/2011
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