| LACTATE IMPAIRS VASCULAR PERMEABILITY BY INHIBITING HSPA12B EXPRESSION VIA GPR81-DEPENDENT SIGNALING IN SEPSIS. | LACTATE IMPAIRS VASCULAR PERMEABILITY BY INHIBITING HSPA12B EXPRESSION VIA GPR81-DEPENDENT SIGNALING IN SEPSIS.
Fan M, Yang K, Wang X, Zhang X, Xu J, Tu F, Gill PS, Ha T, Williams DL, Li C., Free PMC Article | 10/29/2022 |
| Endothelial cell HSPA12B and yes-associated protein cooperatively regulate angiogenesis following myocardial infarction. | Endothelial cell HSPA12B and yes-associated protein cooperatively regulate angiogenesis following myocardial infarction.
Fan M, Yang K, Wang X, Wang Y, Tu F, Ha T, Liu L, Williams DL, Li C., Free PMC Article | 06/5/2021 |
| Novel Role of Endothelial Derived Exosomal HSPA12B in Regulating Macrophage Inflammatory Responses in Polymicrobial Sepsis. | Novel Role of Endothelial Derived Exosomal HSPA12B in Regulating Macrophage Inflammatory Responses in Polymicrobial Sepsis.
Tu F, Wang X, Zhang X, Ha T, Wang Y, Fan M, Yang K, Gill PS, Ozment TR, Dai Y, Liu L, Williams DL, Li C., Free PMC Article | 04/3/2021 |
| Endothelial HSPA12B Exerts Protection Against Sepsis-Induced Severe Cardiomyopathy via Suppression of Adhesion Molecule Expression by miR-126. | Endothelial HSPA12B Exerts Protection Against Sepsis-Induced Severe Cardiomyopathy via Suppression of Adhesion Molecule Expression by miR-126.
Zhang X, Wang X, Fan M, Tu F, Yang K, Ha T, Liu L, Kalbfleisch J, Williams D, Li C., Free PMC Article | 03/27/2021 |
| HSPA12B promoted functional recovery and survival after stroke in an eNOS-dependent mechanism. | HSPA12B promotes functional recovery after ischaemic stroke through an eNOS-dependent mechanism.
Zhao Y, Liu C, Liu J, Kong Q, Mao Y, Cheng H, Li N, Zhang X, Li C, Li Y, Liu L, Ding Z., Free PMC Article | 11/9/2019 |
| These results demonstrate a pulmonary protective effect of HSPA12B against endotoxin challenge, which indicates management of HSPA12B expression could serve as a potential therapeutic target for ALI during sepsis/septic shock. | HSPA12B attenuates acute lung injury during endotoxemia in mice.
Zhang X, Li J, Li C, Li Y, Zhu W, Zhou H, Ding Z, Liu L. | 10/1/2016 |
| HSPA12B plays a protective role in vascular endothelial barrier dysfunction by preserving the endothelial permeability during sepsis. | Heat shock protein A12B protects against sepsis-induced impairment in vascular endothelial permeability.
Kang Q, Chen Y, Zhang X, Yu G, Wan X, Wang J, Bo L, Zhu K. | 09/10/2016 |
| Results suggest that miR-134 might influence neuronal cell survival against ischemic injury in primary cultured neuronal cells and mouse brain with ischemic stroke by negatively modulating HSPA12B protein expression in a posttranscriptional manner | Impact of microRNA-134 on neural cell survival against ischemic injury in primary cultured neuronal cells and mouse brain with ischemic stroke by targeting HSPA12B.
Chi W, Meng F, Li Y, Li P, Wang G, Cheng H, Han S, Li J. | 08/1/2015 |
| Results show that downregulation of miR-134 could induce neuroprotection against ischemic injury by upregulation of HSPA12B protein expression in vivo and in vitro models | Downregulation of miRNA-134 protects neural cells against ischemic injury in N2A cells and mouse brain with ischemic stroke by targeting HSPA12B.
Chi W, Meng F, Li Y, Wang Q, Wang G, Han S, Wang P, Li J. | 06/20/2015 |
| Plasma extracellular HSPA12B is elevated in both septic mice and patients. | Plasma HSPA12B is a potential predictor for poor outcome in severe sepsis.
Zhang R, Wan XJ, Zhang X, Kang QX, Bian JJ, Yu GF, Wang JF, Zhu KM., Free PMC Article | 02/14/2015 |
| inhibition of eNOS abrogated the protection of HSPA12B against cardiac dysfunction and remodelling after myocardial infarction | HSPA12B attenuates cardiac dysfunction and remodelling after myocardial infarction through an eNOS-dependent mechanism.
Li J, Zhang Y, Li C, Xie J, Liu Y, Zhu W, Zhang X, Jiang S, Liu L, Ding Z. | 05/3/2014 |
| HSPA12A and HSPA12B may play roles in genetic susceptibility to atherosclerosis | Two Hsp70 family members expressed in atherosclerotic lesions.
Han Z, Truong QA, Park S, Breslow JL., Free PMC Article | 01/21/2010 |