| Phage display identification of high-affinity ligands for human TSG101-UEV: A structural and thermodynamic study of PTAP recognition. | Phage display identification of high-affinity ligands for human TSG101-UEV: A structural and thermodynamic study of PTAP recognition.
Murciano-Calles J, Rodríguez-Martínez A, Palencia A, Andújar-Sánchez M, Iglesias-Bexiga M, Corbi-Verge C, Buzón P, Ruiz-Sanz J, Martínez JC, Pérez-Sánchez H, Cámara-Artigas A, Luque I. | 07/29/2024 |
| Analysis of the Expression of LSF Transcription Factor in the Regulation of Transcription and TSG101 during the Neoplastic Transformation of Endometrial Cells. | Analysis of the Expression of LSF Transcription Factor in the Regulation of Transcription and TSG101 during the Neoplastic Transformation of Endometrial Cells.
Ziemiński R, Stupak A, Kwiatek M, Gęca T, Warowicka A, Hejne K, Kwaśniewska A, Goździcka-Józefiak A, Kwaśniewski W., Free PMC Article | 04/23/2024 |
| Interaction of TSG101 with the PTAP Motif in Distinct Locations of Gag Determines the Incorporation of HTLV-1 Env into the Retroviral Virion. | Interaction of TSG101 with the PTAP Motif in Distinct Locations of Gag Determines the Incorporation of HTLV-1 Env into the Retroviral Virion.
Maeda Y, Monde K, Terasawa H, Tanaka Y, Sawa T., Free PMC Article | 12/4/2023 |
| Morphogenesis of Bullet-Shaped Rabies Virus Particles Regulated by TSG101. | Morphogenesis of Bullet-Shaped Rabies Virus Particles Regulated by TSG101.
Itakura Y, Tabata K, Saito T, Intaruck K, Kawaguchi N, Kishimoto M, Torii S, Kobayashi S, Ito N, Harada M, Inoue S, Maeda K, Takada A, Hall WW, Orba Y, Sawa H, Sasaki M., Free PMC Article | 06/5/2023 |
| HECT domain interaction with ubiquitin binding sites on Tsg101-UEV controls HIV-1 egress, maturation, and infectivity. | HECT domain interaction with ubiquitin binding sites on Tsg101-UEV controls HIV-1 egress, maturation, and infectivity.
Nyenhuis DA, Rajasekaran R, Watanabe S, Strub MP, Khan M, Powell M, Carter CA, Tjandra N., Free PMC Article | 02/24/2023 |
| Epstein-Barr Virus Enhances Cancer-Specific Aberrant Splicing of TSG101 Pre-mRNA. | Epstein-Barr Virus Enhances Cancer-Specific Aberrant Splicing of TSG101 Pre-mRNA.
Chua HH, Kameyama T, Mayeda A, Yeh TH., Free PMC Article | 07/16/2022 |
| Tsg101/ESCRT-I recruitment regulated by the dual binding modes of K63-linked diubiquitin. | Tsg101/ESCRT-I recruitment regulated by the dual binding modes of K63-linked diubiquitin.
Strickland M, Watanabe S, Bonn SM, Camara CM, Starich MR, Fushman D, Carter CA, Tjandra N., Free PMC Article | 03/26/2022 |
| Knockdown of ANXA10 inhibits proliferation and promotes apoptosis of papillary thyroid carcinoma cells by down-regulating TSG101 thereby inactivating the MAPK/ERK signaling pathway. | Knockdown of ANXA10 inhibits proliferation and promotes apoptosis of papillary thyroid carcinoma cells by down-regulating TSG101 thereby inactivating the MAPK/ERK signaling pathway.
Wei T, Zhu X. | 02/19/2022 |
| AKTIP interacts with ESCRT I and is needed for the recruitment of ESCRT III subunits to the midbody. | AKTIP interacts with ESCRT I and is needed for the recruitment of ESCRT III subunits to the midbody.
Merigliano C, Burla R, La Torre M, Del Giudice S, Teo H, Liew CW, Chojnowski A, Goh WI, Olmos Y, Maccaroni K, Giubettini M, Chiolo I, Carlton JG, Raimondo D, Vernì F, Stewart CL, Rhodes D, Wright GD, Burke BE, Saggio I., Free PMC Article | 12/11/2021 |
| Tumor Susceptibility Gene 101 Regulates the Glucocorticoid Receptor through Disorder-Mediated Allostery. | Tumor Susceptibility Gene 101 Regulates the Glucocorticoid Receptor through Disorder-Mediated Allostery.
White JT, Rives J, Tharp ME, Wrabl JO, Thompson EB, Hilser VJ. | 11/22/2021 |
| TSG101 Promotes the Proliferation, Migration, and Invasion of Human Glioma Cells by Regulating the AKT/GSK3beta/beta-Catenin and RhoC/Cofilin Pathways. | TSG101 Promotes the Proliferation, Migration, and Invasion of Human Glioma Cells by Regulating the AKT/GSK3β/β-Catenin and RhoC/Cofilin Pathways.
Zhu Y, Xu Y, Chen T, Zhang Y, Ma Q, Rauniyar S, Wang L, Shi H. | 11/22/2021 |
| Circulating small extracellular vesicles increase after an acute bout of moderate-intensity exercise in pregnant compared to non-pregnant women. | Circulating small extracellular vesicles increase after an acute bout of moderate-intensity exercise in pregnant compared to non-pregnant women.
Mohammad S, Hutchinson KA, da Silva DF, Bhattacharjee J, McInnis K, Burger D, Adamo KB., Free PMC Article | 11/6/2021 |
| Concurrent depletion of Vps37 proteins evokes ESCRT-I destabilization and profound cellular stress responses. | Concurrent depletion of Vps37 proteins evokes ESCRT-I destabilization and profound cellular stress responses.
Kolmus K, Erdenebat P, Szymańska E, Stewig B, Goryca K, Derezińska-Wołek E, Szumera-Ciećkiewicz A, Brewińska-Olchowik M, Piwocka K, Prochorec-Sobieszek M, Mikula M, Miączyńska M. | 07/31/2021 |
| High expression of tumor susceptibility gene 101 (TSG101) is associated with more aggressive behavior in colorectal carcinoma. | High expression of tumor susceptibility gene 101 (TSG101) is associated with more aggressive behavior in colorectal carcinoma.
Gheytanchi E, Saeednejad Zanjani L, Ghods R, Abolhasani M, Shahin M, Vafaei S, Naseri M, Fattahi F, Madjd Z. | 05/29/2021 |
| An ESCRT-dependent step in fatty acid transfer from lipid droplets to mitochondria through VPS13D-TSG101 interactions. | An ESCRT-dependent step in fatty acid transfer from lipid droplets to mitochondria through VPS13D-TSG101 interactions.
Wang J, Fang N, Xiong J, Du Y, Cao Y, Ji WK., Free PMC Article | 03/6/2021 |
| Proline-rich domain of human ALIX contains multiple TSG101-UEV interaction sites and forms phosphorylation-mediated reversible amyloids. | Proline-rich domain of human ALIX contains multiple TSG101-UEV interaction sites and forms phosphorylation-mediated reversible amyloids.
Elias RD, Ma W, Ghirlando R, Schwieters CD, Reddy VS, Deshmukh L., Free PMC Article | 12/19/2020 |
| Authors used CRISPR/Cas9-mediated knock-in to tag the critical ESCRT-I component tumor susceptibility 101 (Tsg101) with GFP at its native locus in two widely used human cell types, HeLa epithelial cells and Jurkat T cells. | Genomic tagging of endogenous human ESCRT-I complex preserves ESCRT-mediated membrane-remodeling functions.
Hoffman HK, Fernandez MV, Groves NS, Freed EO, van Engelenburg SB., Free PMC Article | 07/25/2020 |
| This study shows that SH3YL1 cooperates with ESCRT-I in the sorting and degradation of the EGF receptor. | SH3YL1 cooperates with ESCRT-I in the sorting and degradation of the EGF receptor.
Hasegawa J, Jebri I, Yamamoto H, Tsujita K, Tokuda E, Shibata H, Maki M, Itoh T. | 07/25/2020 |
| We found that inhibition of CD133 complex-type N-glycosylation by swainsonine does not affect the membrane localization of CD133, but significantly reduces CD133 secretion and promotes its accumulation in early endosomes. Moreover, swainsonine reduces CD133 secretion by reducing its mono-ubiquitination and inhibiting the interaction between CD133 and Tsg101. | Complex N-glycan promotes CD133 mono-ubiquitination and secretion.
Li Y, Shi D, Yang F, Chen X, Xing Y, Liang Z, Zhuang J, Liu W, Gong Y, Jiang J, Wei Y. | 05/16/2020 |
| Results suggest that tumour susceptibility gene 101 (TSG101) is up-regulated in hepatocellular carcinoma (HCC) patients, which may accelerate the proliferation, migration and invasion of HCC cells through paternally expressed 10 protein (PEG10). | TSG101 promotes the proliferation, migration and invasion of hepatocellular carcinoma cells by regulating the PEG10.
Liu Z, Tian Z, Cao K, Zhang B, Wen Q, Zhou X, Yang W, Wang T, Shi H, Wang R., Free PMC Article | 04/11/2020 |
| By increasing the stability of the TSG101 protein, TSG101154-1054 specifically enhanced TSG101-mediated TW01 cell migration and invasion, suggesting the involvement in NPC metastasis in vivo. This finding sheds light on the functional significance of TSG101154-1054 generation via re-splicing of TSG101 mRNA in NPC metastasis. | Cancer-Specifically Re-Spliced TSG101 mRNA Promotes Invasion and Metastasis of Nasopharyngeal Carcinoma.
Chua HH, Kameyama T, Mayeda A, Yeh TH., Free PMC Article | 06/8/2019 |
| TSG101 promotes proliferation of renal cell carcinoma cells | siRNA against TSG101 reduces proliferation and induces G0/G1 arrest in renal cell carcinoma - involvement of c-myc, cyclin E1, and CDK2.
Xu C, Zheng J., Free PMC Article | 04/20/2019 |
| identification of HIV-1 Gag-TSG101 interaction inhibitors. | Identification of human immunodeficiency virus type-1 Gag-TSG101 interaction inhibitors by high-throughput screening.
Siarot L, Chutiwitoonchai N, Sato H, Chang H, Sato H, Fujino M, Murakami T, Aono T, Kodama E, Kuroda K, Takei M, Aida Y. | 01/19/2019 |
| this is the first study that implicates the importance of TSG101 in anoikis resistance of thyroid cancer. | Tumor Susceptibility Gene 101 Mediates Anoikis Resistance of Metastatic Thyroid Cancer Cells.
Saharat K, Lirdprapamongkol K, Chokchaichamnankit D, Srisomsap C, Svasti J, Paricharttanakul NM., Free PMC Article | 12/22/2018 |
| In LNCaP prostate cancer cells, TSG101 overexpression recruits the androgen receptor (AR) to TSG101-containing cytoplasmic vesicles resulting in reduced AR protein level and AR transactivation activity downregulation. Immunofluorescence microscopy demonstrated that TSG101-decorated cytoplasmic vesicles are associated with late endosomes/lysosomes. | TSG101 interacts with the androgen receptor and attenuates its expression through the endosome/lysosome pathway.
Lin YM, Chu PH, Ouyang P. | 12/1/2018 |