Identification of a novel TSC1 variant in a family with developmental and epileptic encephalopathies: A case report and literature review.
Wang C, Zhai JX, Chen YJ., Free PMC Article

miR-27a-3p promotes inflammatory response in infectious endophthalmitis via targeting TSC1.
Chen Y, Li S, He H., Free PMC Article

The role of TSC1 and TSC2 proteins in neuronal axons.
Karalis V, Wood D, Teaney NA, Sahin M.

CBAP regulates the function of Akt-associated TSC protein complexes to modulate mTORC1 signaling.
Liao WT, Chiang YJ, Yang-Yen HF, Hsu LC, Chang ZF, Yen JJY., Free PMC Article

Tuberous sclerosis complex-1 (TSC1) contributes to selective neuronal vulnerability in Alzheimer's disease.
Adriaanse BA, Brady S, Wang M, Beard DJ, Spencer JI, Pansieri J, Sutherland BA, Esiri MM, Buchan AM, Cader Z, Zhang B, DeLuca GC.

TSC/MTOR mutated renal cell carcinoma with leiomyomatous stroma is a distinct entity: a comprehensive study of 12 cases.
Tjota MY, Sharma A, Wanjari P, Fitzpatrick C, Segal J, Antic T.

TSC/MTOR -associated Eosinophilic Renal Tumors Exhibit a Heterogeneous Clinicopathologic Spectrum : Several Distinct Entities or a Tumor Family?
Trpkov K.

Refractive Errors, Retinal Findings, and Genotype of Tuberous Sclerosis Complex: A Retrospective Cohort Study.
Ryu S, Kang HC, Lee SC, Byeon SH, Kim SS, Lee CS., Free PMC Article

Somatic mutations involving TSC 1 and TSC2 genes in two children with focal cortical dysplasia.
Jha R, Kurup A, Kovilapu UB, Ranjan R, Sondhi V.

Loss of TSC1/TSC2 sensitizes immune checkpoint blockade in non-small cell lung cancer.
Huang Q, Li F, Hu H, Fang Z, Gao Z, Xia G, Ng WL, Khodadadi-Jamayran A, Chen T, Deng J, Zhang H, Almonte C, Labbe K, Han H, Geng K, Tang S, Freeman GJ, Li Y, Chen H, Wong KK., Free PMC Article

Low-grade oncocytic tumor of kidney harboring TSC/MTOR mutation: clinicopathologic, immunohistochemical and molecular characteristics support a distinct entity.
Zhang HZ, Xia QY, Wang SY, Shi MJ, Wang SY.

Uterine PEComas: correlation between melanocytic marker expression and TSC alterations/TFE3 fusions.
Bennett JA, Ordulu Z, Pinto A, Wanjari P, Antonescu CR, Ritterhouse LL, Oliva E., Free PMC Article

Detection of TSC1/TSC2 mosaic variants in patients with cardiac rhabdomyoma and tuberous sclerosis complex by hybrid-capture next-generation sequencing.
Wang S, Sun H, Wang J, Gu X, Han L, Wu Y, Yan H, Han L, Zhang H, He Y., Free PMC Article

Low-level mosaicism in tuberous sclerosis complex in four unrelated patients: Comparison of clinical characteristics and diagnostic pathways.
Manzanilla-Romero HH, Weis D, Schnaiter S, Rudnik-Schöneborn S., Free PMC Article

Whole Exome Sequencing in a Series of Patients with a Clinical Diagnosis of Tuberous Sclerosis Not Confirmed by Targeted TSC1/TSC2 Sequencing.
Kovesdi E, Ripszam R, Postyeni E, Horvath EB, Kelemen A, Fabos B, Farkas V, Hadzsiev K, Sumegi K, Magyari L, Moreno PG, Bauer P, Melegh B., Free PMC Article

Renal Cell Carcinoma in Tuberous Sclerosis Complex.
Henske EP, Cornejo KM, Wu CL., Free PMC Article

UBE2S exerts oncogenic activities in urinary bladder cancer by ubiquitinating TSC1.
Tang H, Fang T, Ji M, Wang JP, Song LL, Zhang QY, Wu JS.

Comprehensive Genetic Analysis Results of TSC1/TSC2 Genes in Patients with Clinical Suspicion of Tuberous Sclerosis Complex and Definition of 3 Novel Variants.
Demir S, Yalçıntepe S, Atlı E, Yalçın Y, İkbal Atlı E, Eker D, Karal Y, Gürkan H., Free PMC Article

Long noncoding RNA KB-1460A1.5 inhibits glioma tumorigenesis via miR-130a-3p/TSC1/mTOR/YY1 feedback loop.
Xu L, Wu Q, Yan H, Shu C, Fan W, Tong X, Li Q.

Dampened VEPH1 activates mTORC1 signaling by weakening the TSC1/TSC2 association in hepatocellular carcinoma.
Dong P, Wang X, Liu L, Tang W, Ma L, Zeng W, Sun S, Zhang L, Zhang N, Shen X, Janssen HLA, Dong L, Zhang S, Chen S.

A Bama miniature pig model of monoallelic TSC1 mutation for human tuberous sclerosis complex.
Li X, Hu T, Liu J, Fang B, Geng X, Xiong Q, Zhang L, Jin Y, Liu X, Li L, Wang Y, Li R, Bai X, Yang H, Dai Y.

Identification of TSC1 or TSC2 mutation limited to the tumor in three cases of solitary subependymal giant cell astrocytoma using next-generation sequencing technology.
Fohlen M, Harzallah I, Polivka M, Giuliano F, Pons L, Streichenberger N, Dorfmüller G, Touraine R.

Upregulation of 6-phosphofructo-2-kinase (PFKFB3) by hyperactivated mammalian target of rapamycin complex 1 is critical for tumor growth in tuberous sclerosis complex.
Wang Y, Tang S, Wu Y, Wan X, Zhou M, Li H, Zha X.

Identification of novel mutations in TSC1 and TSC2 for tuberous sclerosis complex by targeted next-generation sequencing and ACMG guidelines.
He L, Ye W, Chen Z, Meng X, Jiang H.

Antiproliferative effect of bacterial cyclodipeptides in the HeLa line of human cervical cancer reveals multiple protein kinase targeting, including mTORC1/C2 complex inhibition in a TSC1/2-dependent manner.
Hernández-Padilla L, Reyes de la Cruz H, Campos-García J.