| MicroRNA-1 Deficiency Is a Primary Etiological Factor Disrupting Cardiac Contractility and Electrophysiological Homeostasis. | MicroRNA-1 Deficiency Is a Primary Etiological Factor Disrupting Cardiac Contractility and Electrophysiological Homeostasis.
Yang D, Wan X, Schwieterman N, Cavus O, Kacira E, Xu X, Laurita KR, Wold LE, Hund TJ, Mohler PJ, Deschênes I, Fu JD., Free PMC Article | 06/26/2024 |
| Long noncoding RNA AI504432 upregulates FASN expression by sponging miR-1a-3p to promote lipogenesis in senescent adipocytes. | Long noncoding RNA AI504432 upregulates FASN expression by sponging miR-1a-3p to promote lipogenesis in senescent adipocytes.
Wang S, Wang R, Hu Y, Zhang Y, Yuan Q, Luo Y, Yuan C. | 06/21/2024 |
| Cripto Is Targeted by miR-1a-3p in a Mouse Model of Heart Development. | Cripto Is Targeted by miR-1a-3p in a Mouse Model of Heart Development.
Angrisano T, Varrone F, Ragozzino E, Fico A, Minchiotti G, Brancaccio M., Free PMC Article | 08/14/2023 |
| Distress-Mediated Remodeling of Cardiac Connexin-43 in a Novel Cell Model for Arrhythmogenic Heart Diseases. | Distress-Mediated Remodeling of Cardiac Connexin-43 in a Novel Cell Model for Arrhythmogenic Heart Diseases.
Wahl CM, Schmidt C, Hecker M, Ullrich ND., Free PMC Article | 09/17/2022 |
| Excessive expression of miR-1a by statin causes skeletal injury through targeting mitogen-activated protein kinase kinase kinase 1. | Excessive expression of miR-1a by statin causes skeletal injury through targeting mitogen-activated protein kinase kinase kinase 1.
Fu CN, Song JW, Song ZP, Wang QW, Bai WW, Guo T, Li P, Liu C, Wang SX, Dong B., Free PMC Article | 07/31/2021 |
| MicroRNA-1 promotes cartilage matrix synthesis and regulates chondrocyte differentiation via post-transcriptional suppression of Ihh expression. | MicroRNA-1 promotes cartilage matrix synthesis and regulates chondrocyte differentiation via post-transcriptional suppression of Ihh expression.
Chen T, Che X, Han P, Lu J, Wang C, Liang B, Hou Z, Wei X, Wei L, Li P., Free PMC Article | 05/1/2021 |
| An endothelial microRNA-1-regulated network controls eosinophil trafficking in asthma and chronic rhinosinusitis. | An endothelial microRNA-1-regulated network controls eosinophil trafficking in asthma and chronic rhinosinusitis.
Korde A, Ahangari F, Haslip M, Zhang X, Liu Q, Cohn L, Gomez JL, Chupp G, Pober JS, Gonzalez A, Takyar SS., Free PMC Article | 09/26/2020 |
| This study demonstrates that myocardial infarction leads to overexpression of miR-1 in the hippocampus that was transported by exosomes from infarcted hearts. This study reveals a novel insight into the molecular mechanisms of heart-to-brain communication at the miRNA level. | Myocardial infarction-induced hippocampal microtubule damage by cardiac originating microRNA-1 in mice.
Sun LL, Duan MJ, Ma JC, Xu L, Mao M, Biddyut D, Wang Q, Yang C, Zhang S, Xu Y, Yang L, Tian Y, Liu Y, Xia SN, Li KX, Jin Z, Xiong Q, Ai J. | 10/26/2019 |
| Results presented here suggest that significantly elevated levels of miRNA-1 in post-myocardial infarction old heart could be predictive of cardiac injury in older mice as the high risk biomarker for myocardial infarction in older individuals. | MicroRNAs as predictive biomarkers for myocardial injury in aged mice following myocardial infarction.
Qipshidze Kelm N, Piell KM, Wang E, Cole MP. | 05/18/2019 |
| MiR-1 levels were increased, while, BDNF protein expression was significantly reduced in the hippocampi of myocardial infarction mice, indicating that miR-1 can inhibit BDNF protein expression in myocardial infarction mice. | Knockdown of MicroRNA-1 in the Hippocampus Ameliorates Myocardial Infarction Induced Impairment of Long-Term Potentiation.
Ma JC, Duan MJ, Li KX, Biddyut D, Zhang S, Yan ML, Yang L, Jin Z, Zhao HM, Huang SY, Sun Q, Su D, Xu Y, Pan YH, Ai J. | 11/10/2018 |
| Coxsackievirus B3 infection reduced Cx43 expression by elevating miR-1 level in mouse viral myocarditis. | Astragalus Root dry extract restores connexin43 expression by targeting miR-1 in viral myocarditis.
Wang Y, Li J, Xuan L, Liu Y, Shao L, Ge H, Gu J, Wei C, Zhao M. | 08/18/2018 |
| miR-1 can target HSP-70 expression and consequently mediate hypoxia-induced apoptotic insults to neuro-2a cells via an intrinsic Bax-mitochondrion-caspase protease pathway. | Roles of microRNA-1 in hypoxia-induced apoptotic insults to neuronal cells.
Chang CY, Lui TN, Lin JW, Lin YL, Hsing CH, Wang JJ, Chen RM. | 10/22/2016 |
| Results suggest that miR-1/133a miRNA clusters to be important to prevent a longQT-phenotype in the mammalian heart. | MiRNA-1/133a clusters regulate adrenergic control of cardiac repolarization.
Besser J, Malan D, Wystub K, Bachmann A, Wietelmann A, Sasse P, Fleischmann BK, Braun T, Boettger T., Free PMC Article | 01/2/2016 |
| MiR-1 participates in NO-induced apoptotic insults through targeting HSP-70 gene expression. | MicroRNA-1 participates in nitric oxide-induced apoptotic insults to MC3T3-E1 cells by targeting heat-shock protein-70.
Lee YE, Hong CY, Lin YL, Chen RM., Free PMC Article | 11/21/2015 |
| The miR1-2 orchestrate a genetic pathway involving Errbeta that represses the cardiac fetal gene program in a multifaceted way. | Multifaceted roles of miR-1s in repressing the fetal gene program in the heart.
Wei Y, Peng S, Wu M, Sachidanandam R, Tu Z, Zhang S, Falce C, Sobie EA, Lebeche D, Zhao Y., Free PMC Article | 04/25/2015 |
| Findings unveil a positive function of microRNA in mitochondrial translation and suggest a highly coordinated myogenic program via miR-1-mediated translational stimulation in the mitochondria and repression in the cytoplasm. | MicroRNA directly enhances mitochondrial translation during muscle differentiation.
Zhang X, Zuo X, Yang B, Li Z, Xue Y, Zhou Y, Huang J, Zhao X, Zhou J, Yan Y, Zhang H, Guo P, Sun H, Guo L, Zhang Y, Fu XD., Free PMC Article | 02/7/2015 |
| The overexpression of miR-1 suppresses endogenous BDNF protein levels and that silencing endogenous miR-10b increases BDNF mRNA and protein levels. | miR-1, miR-10b, miR-155, and miR-191 are novel regulators of BDNF.
Varendi K, Kumar A, Härma MA, Andressoo JO., Free PMC Article | 12/27/2014 |
| The simultaneous downregulation of miR-1a in lung tissues and serum in urethane-induced pulmonary carcinogenesis suggests that miR-1a is associated with tumorigenesis. | Altered miRNA expression profiles and miR-1a associated with urethane-induced pulmonary carcinogenesis.
Li X, Wu J, Zheng J, Li Y, Yang T, Hu G, Dai J, Yang Q, Dai L, Jiang Y. | 05/17/2014 |
| MiR-1 contributes to endothelial barrier function via mechanisms involving MLCK expression and ERK phosphorylation. | MicroRNA-1 prevents high-fat diet-induced endothelial permeability in apoE knock-out mice.
Wang H, Zhu HQ, Wang F, Zhou Q, Gui SY, Wang Y., Free PMC Article | 11/16/2013 |
| miR-1 overexpression enhances Ca(2+) release and promotes cardiac arrhythmogenesis by targeting PP2A regulatory subunit B56alpha and causing CaMKII-dependent hyperphosphorylation of RyR2. | miR-1 overexpression enhances Ca(2+) release and promotes cardiac arrhythmogenesis by targeting PP2A regulatory subunit B56alpha and causing CaMKII-dependent hyperphosphorylation of RyR2.
Terentyev D, Belevych AE, Terentyeva R, Martin MM, Malana GE, Kuhn DE, Abdellatif M, Feldman DS, Elton TS, Györke S., Free PMC Article | 01/21/2010 |
| targeted deletion of miR-1-2 revealed numerous functions in the heart, including regulation of cardiac morphogenesis, electrical conduction, and cell-cycle control | Dysregulation of cardiogenesis, cardiac conduction, and cell cycle in mice lacking miRNA-1-2.
Zhao Y, Ransom JF, Li A, Vedantham V, von Drehle M, Muth AN, Tsuchihashi T, McManus MT, Schwartz RJ, Srivastava D. | 01/21/2010 |