| Hydrogen-rich saline alleviates cardiomyocyte apoptosis by reducing expression of calpain1 via miR-124-3p. | Hydrogen-rich saline alleviates cardiomyocyte apoptosis by reducing expression of calpain1 via miR-124-3p.
Xue X, Xi W, Li W, Xiao J, Wang Z, Zhang Y., Free PMC Article | 10/13/2023 |
| M2 Microglia Extracellular Vesicle miR-124 Regulates Neural Stem Cell Differentiation in Ischemic Stroke via AAK1/NOTCH. | M2 Microglia Extracellular Vesicle miR-124 Regulates Neural Stem Cell Differentiation in Ischemic Stroke via AAK1/NOTCH.
Song Y, Shi R, Liu Y, Cui F, Han L, Wang C, Chen T, Li Z, Zhang Z, Tang Y, Yang GY, Guan Y. | 09/29/2023 |
| MicroRNA-124-3p Attenuated Retinal Neovascularization in Oxygen-Induced Retinopathy Mice by Inhibiting the Dysfunction of Retinal Neuroglial Cells through STAT3 Pathway. | MicroRNA-124-3p Attenuated Retinal Neovascularization in Oxygen-Induced Retinopathy Mice by Inhibiting the Dysfunction of Retinal Neuroglial Cells through STAT3 Pathway.
Hong Y, Wang Y, Cui Y, Pan J, Mao S, Zhu Y, Wen T, Qi T, Wang A, Luo Y., Free PMC Article | 08/3/2023 |
| Role of miR-124-3p in regulatory mechanisms of Gpm6a expression in the hippocampus of chronically stressed rats. | Role of miR-124-3p in regulatory mechanisms of Gpm6a expression in the hippocampus of chronically stressed rats.
Alzuri SE, Rosas NM, Hlavacova N, Jezova D, Fuchsova B. | 05/30/2023 |
| miR-124 Exacerbates depressive-like behavior by targeting Ezh2 to induce autophagy. | miR-124 Exacerbates depressive-like behavior by targeting Ezh2 to induce autophagy.
Zeng D, Shi Y, Li S, Xu F, Zhu W, Li H, He S, Yuan Q. | 03/14/2023 |
| The miR-124-3p regulates the allergic airway inflammation and remodeling in an ovalbumin-asthmatic mouse model by inhibiting S100A4. | The miR-124-3p regulates the allergic airway inflammation and remodeling in an ovalbumin-asthmatic mouse model by inhibiting S100A4.
Liu M, Liu S, Li F, Li C, Chen S, Gao X, Wang X., Free PMC Article | 02/22/2023 |
| miR-124-3p improves mitochondrial function of renal tubular epithelial cells in db/db mice. | miR-124-3p improves mitochondrial function of renal tubular epithelial cells in db/db mice.
Liang L, Wo C, Yuan Y, Cao H, Tan W, Zhou X, Wang D, Chen R, Shi M, Zhang F, Xiao Y, Liu L, Zhou Y, Zhang T, Wang Y, Guo B. | 02/13/2023 |
| m(6)A methyltransferase METTL3 relieves cognitive impairment of hyperuricemia mice via inactivating MyD88/NF-kappaB pathway mediated NLRP3-ASC-Caspase1 inflammasome. | m(6)A methyltransferase METTL3 relieves cognitive impairment of hyperuricemia mice via inactivating MyD88/NF-κB pathway mediated NLRP3-ASC-Caspase1 inflammasome.
Chen Y, Cao P, Xiao Z, Ruan Z. | 12/17/2022 |
| Mesenchymal stem cell-derived extracellular vesicles prevent the development of osteoarthritis via the circHIPK3/miR-124-3p/MYH9 axis. | Mesenchymal stem cell-derived extracellular vesicles prevent the development of osteoarthritis via the circHIPK3/miR-124-3p/MYH9 axis.
Li S, Liu J, Liu S, Jiao W, Wang X., Free PMC Article | 12/4/2021 |
| Repression of MicroRNA-124-3p Alleviates High-Fat Diet-Induced Hepatosteatosis by Targeting Pref-1. | Repression of MicroRNA-124-3p Alleviates High-Fat Diet-Induced Hepatosteatosis by Targeting Pref-1.
Wang G, Zou H, Lai C, Huang X, Yao Y, Xiang G., Free PMC Article | 06/5/2021 |
| Downregulation of microRNA-124 prevents the development of acute liver failure through the upregulation of PIM-3. | Downregulation of microRNA-124 prevents the development of acute liver failure through the upregulation of PIM-3.
Zan T, Piao L, Yang X, Gu Y, Liu B. | 05/29/2021 |
| MiR-124-3p helps to protect against acute respiratory distress syndrome by targeting p65. | MiR-124-3p helps to protect against acute respiratory distress syndrome by targeting p65.
Liang Y, Xie J, Che D, Zhang C, Lin Y, Feng L, Chen J, Chen J, Chen L, Wu Z., Free PMC Article | 04/3/2021 |
| Retinoic acid receptor gamma is targeted by microRNA-124 and inhibits neurite outgrowth. | Retinoic acid receptor gamma is targeted by microRNA-124 and inhibits neurite outgrowth.
Su X, Gu X, Zhang Z, Li W, Wang X. | 01/9/2021 |
| Cocaine-regulated microRNA miR-124 controls poly (ADP-ribose) polymerase-1 expression in neuronal cells. | Cocaine-regulated microRNA miR-124 controls poly (ADP-ribose) polymerase-1 expression in neuronal cells.
Dash S, Balasubramaniam M, Martínez-Rivera FJ, Godino A, Peck EG, Patnaik S, Suar M, Calipari ES, Nestler EJ, Villalta F, Dash C, Pandhare J., Free PMC Article | 12/26/2020 |
| miR-124 regulates cerebromicrovascular function in APP/PS1 transgenic mice via C1ql3. | miR-124 regulates cerebromicrovascular function in APP/PS1 transgenic mice via C1ql3.
Li AD, Tong L, Xu N, Ye Y, Nie PY, Wang ZY, Ji LL. | 09/26/2020 |
| These results show that antagonizing let-7 and increasing levels of miR-25 and miR-124 using miRNA mimics is useful in reprogramming Muller glial cells to retinal neurons in vitro and could help in stimulating regeneration in this system. | MicroRNAs miR-25, let-7 and miR-124 regulate the neurogenic potential of Müller glia in mice.
Wohl SG, Hooper MJ, Reh TA., Free PMC Article | 07/18/2020 |
| Our findings indicate that upregulated miR-124-3p inhibits cell proliferation in cultured lip cells through suppression of CL-associated genes. These results will have a significant impact, not only on our knowledge about lip morphogenesis, but also on the development of clinical approaches for the diagnosis and prevention of CL. | MicroRNA-124-3p suppresses mouse lip mesenchymal cell proliferation through the regulation of genes associated with cleft lip in the mouse.
Suzuki A, Yoshioka H, Summakia D, Desai NG, Jun G, Jia P, Loose DS, Ogata K, Gajera MV, Zhao Z, Iwata J., Free PMC Article | 04/4/2020 |
| MiR-124-3p inhibits neuronal apoptosis, negatively regulates SPTLC2 expression, and suppresses the apoptosis-promoting effect of SPTLC2 via the TLR4 signaling pathway. | The Effect of SPTLC2 on Promoting Neuronal Apoptosis is Alleviated by MiR-124-3p Through TLR4 Signalling Pathway.
Su X, Ye Y, Yang Y, Zhang K, Bai W, Chen H, Kang E, Kong C, He X. | 01/25/2020 |
| increased miR-124-3p in microglial exosomes following TBI may inhibit neuronal autophagy and protect against nerve injury via their transfer into neurons. | Increases in miR-124-3p in Microglial Exosomes Confer Neuroprotective Effects by Targeting FIP200-Mediated Neuronal Autophagy Following Traumatic Brain Injury.
Li D, Huang S, Yin Z, Zhu J, Ge X, Han Z, Tan J, Zhang S, Zhao J, Chen F, Wang H, Lei P. | 01/11/2020 |
| microRNA (miR-124-3p) mediates regulation of glucocorticoid receptor (GR) by myostatin. miR-124-3p can target GR 3'-UTR and negatively regulate GR expression. Overexpression of miR-124-3p can reduce adipogenesis, differentiation of 3T3-L1 cells, by inhibiting GR, and vice versa. | Myostatin/SMAD4 signaling-mediated regulation of miR-124-3p represses glucocorticoid receptor expression and inhibits adipocyte differentiation.
Liu K, Zhang X, Wei W, Liu X, Tian Y, Han H, Zhang L, Wu W, Chen J. | 12/21/2019 |
| HDAC5 emerges as a cellular conductor of MEF2C and M6a activity and is regulated by miR-124 and miR-9 to control neurite development. | miR-124 and miR-9 mediated downregulation of HDAC5 promotes neurite development through activating MEF2C-GPM6A pathway.
Gu X, Fu C, Lin L, Liu S, Su X, Li A, Wu Q, Jia C, Zhang P, Chen L, Zhu X, Wang X. | 10/28/2017 |
| miR-124a may be involved in the regulation of several cellular and organismal metabolic parameters, including lipid storage and plasma fatty acid concentration. | Micro RNA-124a regulates lipolysis via adipose triglyceride lipase and comparative gene identification 58.
Das SK, Stadelmeyer E, Schauer S, Schwarz A, Strohmaier H, Claudel T, Zechner R, Hoefler G, Vesely PW., Free PMC Article | 01/16/2016 |
| Study demonstrated a novel role of miR-124 and Dlx5 in regulating the differentiation of mesenchymal stem cells toward the myogenic lineage, that is, miR-124 inhibits myogenic differentiation partially through targeting Dlx5 expression. | MiR-124 inhibits myogenic differentiation of mesenchymal stem cells via targeting Dlx5.
Qadir AS, Woo KM, Ryoo HM, Yi T, Song SU, Baek JH. | 10/17/2015 |
| microRNA miR-124a is reduced when proinflammatory mediator expression is increased in KLF2-deficient macrophages. | Reduced levels of microRNAs miR-124a and miR-150 are associated with increased proinflammatory mediator expression in Krüppel-like factor 2 (KLF2)-deficient macrophages.
Manoharan P, Basford JE, Pilcher-Roberts R, Neumann J, Hui DY, Lingrel JB., Free PMC Article | 01/24/2015 |
| Data indicate that direct miR-124a transfection significantly and selectively increases protein expression levels of GLT1 in cultured astrocytes. | Neuronal exosomal miRNA-dependent translational regulation of astroglial glutamate transporter GLT1.
Morel L, Regan M, Higashimori H, Ng SK, Esau C, Vidensky S, Rothstein J, Yang Y., Free PMC Article | 05/4/2013 |