| MicroRNA-335-5p suppresses voltage-gated sodium channel expression and may be a target for seizure control. | MicroRNA-335-5p suppresses voltage-gated sodium channel expression and may be a target for seizure control.
Heiland M, Connolly NMC, Mamad O, Nguyen NT, Kesavan JC, Langa E, Fanning K, Sanfeliu A, Yan Y, Su J, Venø MT, Costard LS, Neubert V, Engel T, Hill TDM, Freiman TM, Mahesh A, Tiwari VK, Rosenow F, Bauer S, Kjems J, Morris G, Henshall DC., Free PMC Article | 09/8/2023 |
| Circ_0101874 overexpression strengthens PDE4D expression by targeting miR-335-5p to promote neuronal injury in ischemic stroke. | Circ_0101874 overexpression strengthens PDE4D expression by targeting miR-335-5p to promote neuronal injury in ischemic stroke.
Pei L, Xu X, Yuan T. | 12/3/2022 |
| Upregulation of miR-335-5p Contributes to Right Ventricular Remodeling via Calumenin in Pulmonary Arterial Hypertension. | Upregulation of miR-335-5p Contributes to Right Ventricular Remodeling via Calumenin in Pulmonary Arterial Hypertension.
Ma H, Ye P, Zhang AK, Yu WD, Lin S, Zheng YG., Free PMC Article | 10/22/2022 |
| Upregulation of miR335 exerts protective effects against sepsisinduced myocardial injury. | Upregulation of miR‑335 exerts protective effects against sepsis‑induced myocardial injury.
Long X, Huang Y, He J, Zhang X, Zhou Y, Wei Y, Tang Y, Liu L., Free PMC Article | 01/22/2022 |
| miR-708 and miR-335-3p Inhibit the Apoptosis of Retinal Ganglion Cells Through Suppressing Autophagy. | miR-708 and miR-335-3p Inhibit the Apoptosis of Retinal Ganglion Cells Through Suppressing Autophagy.
Zhang Q, He C, Li R, Ke Y, Sun K, Wang J. | 10/9/2021 |
| Inhibition of Long Noncoding RNA SNHG20 Improves Angiotensin II-Induced Cardiac Fibrosis and Hypertrophy by Regulating the MicroRNA 335/Galectin-3 Axis. | Inhibition of Long Noncoding RNA SNHG20 Improves Angiotensin II-Induced Cardiac Fibrosis and Hypertrophy by Regulating the MicroRNA 335/Galectin-3 Axis.
Li M, Qi C, Song R, Xiong C, Zhong X, Song Z, Ning Z, Song X., Free PMC Article | 09/4/2021 |
| Up-regulation of microRNA-335-5p reduces inflammation via negative regulation of the TPX2-mediated AKT/GSK3beta signaling pathway in a chronic rhinosinusitis mouse model. | Up-regulation of microRNA-335-5p reduces inflammation via negative regulation of the TPX2-mediated AKT/GSK3β signaling pathway in a chronic rhinosinusitis mouse model.
Gu X, Yao X, Liu D. | 08/14/2021 |
| LncRNA-Gm2044 is transcriptionally activated by A-MYB and regulates Sycp1 expression as a miR-335-3p sponge in mouse spermatocyte-derived GC-2spd(ts) cells. | LncRNA-Gm2044 is transcriptionally activated by A-MYB and regulates Sycp1 expression as a miR-335-3p sponge in mouse spermatocyte-derived GC-2spd(ts) cells.
Liang M, Wang H, He C, Zhang K, Hu K. | 07/17/2021 |
| Upregulation of miR-335-3p by NF-kappaB Transcriptional Regulation Contributes to the Induction of Pulmonary Arterial Hypertension via APJ during Hypoxia. | Upregulation of miR-335-3p by NF-κB Transcriptional Regulation Contributes to the Induction of Pulmonary Arterial Hypertension via APJ during Hypoxia.
Fan J, Fan X, Guang H, Shan X, Tian Q, Zhang F, Chen R, Ye F, Quan H, Zhang H, Ding L, Gan Z, Xue F, Wang Y, Mao S, Hu L, Gong Y., Free PMC Article | 01/9/2021 |
| that miR-335-5p enhanced insulin resistance and suppressed pancreatic islet beta-cell secretion by inhibiting VASH1 | miR-335-5p induces insulin resistance and pancreatic islet β-cell secretion in gestational diabetes mellitus mice through VASH1-mediated TGF-β signaling pathway.
Tang XW, Qin QX. | 04/11/2020 |
| MiR-335 serves as a link between inflammation and impaired metabolism in adipose tissue. | Polyphenol-rich green tea extract improves adipose tissue metabolism by down-regulating miR-335 expression and mitigating insulin resistance and inflammation.
Otton R, Bolin AP, Ferreira LT, Marinovic MP, Rocha ALS, Mori MA. | 11/2/2019 |
| Overexpressed miR-335-5p enhances autophagy by targeting FASN through activation of the AMPK/ULK1 signaling pathway. | Upregulation of microRNA-335-5p reduces inflammatory responses by inhibiting FASN through the activation of AMPK/ULK1 signaling pathway in a septic mouse model.
Gao XL, Li JQ, Dong YT, Cheng EJ, Gong JN, Qin YL, Huang YQ, Yang JJ, Wang SJ, An DD. | 10/26/2019 |
| Findings provide a novel insight into the regulatory role of miR-335-3p in cholesterol metabolism in astrocytes, and consequently cognitive functions during aging. | The Age-dependent Elevation of miR-335-3p Leads to Reduced Cholesterol and Impaired Memory in Brain.
Raihan O, Brishti A, Molla MR, Li W, Zhang Q, Xu P, Khan MI, Zhang J, Liu Q. | 03/23/2019 |
| These results demonstrate constitutive overexpression of miR-335-5p driven by an osterix promoter in the osteoblast lineage induces osteogenic differentiation and bone formation in mice. | Overexpression of MiR-335-5p Promotes Bone Formation and Regeneration in Mice.
Zhang L, Tang Y, Zhu X, Tu T, Sui L, Han Q, Yu L, Meng S, Zheng L, Valverde P, Tang J, Murray D, Zhou X, Drissi H, Dard MM, Tu Q, Chen J., Free PMC Article | 07/28/2018 |
| we showed spatial learning induced down-regulation of miR-335-5p | MicroRNA-335-5p modulates spatial memory and hippocampal synaptic plasticity.
Capitano F, Camon J, Licursi V, Ferretti V, Maggi L, Scianni M, Del Vecchio G, Rinaldi A, Mannironi C, Limatola C, Presutti C, Mele A. | 03/3/2018 |
| These results suggest that Dietary methionine restriction (MR) alters bone remodeling and apposition. In MR mice, miR-31 in plasma and liver, and miR-133a, miR-335-5p, and miR-204 in the bone marrow was elevated. These miRNAs were shown previously to target and regulate Osterix and RUNX2 in bone, which could inhibit osteoblast differentiation and function. | Methionine-Restricted Diet Increases miRNAs That Can Target RUNX2 Expression and Alters Bone Structure in Young Mice.
Plummer J, Park M, Perodin F, Horowitz MC, Hens JR., Free PMC Article | 11/4/2017 |
| These results may indicate that miR3355p overexpression inhibited HGinduced apoptosis of MC3T3E1 osteoblasts through decreasing the protein expression levels of DKK1. | MicroRNA-335-5p inhibits osteoblast apoptosis induced by high glucose.
Li J, Feng Z, Chen L, Wang X, Deng H. | 02/18/2017 |
| Although both Mest and miR-335 are highly expressed during muscle development and regeneration, only Mest+/- (maternal/paternal) mice show retardation of body growth. | Mest but Not MiR-335 Affects Skeletal Muscle Growth and Regeneration.
Hiramuki Y, Sato T, Furuta Y, Surani MA, Sehara-Fujisawa A., Free PMC Article | 04/30/2016 |
| These data showed miR-335-5p positively regulates mesenchymal stem cells chondrogenesis. | MiR-335-5p promotes chondrogenesis in mouse mesenchymal stem cells and is regulated through two positive feedback loops.
Lin X, Wu L, Zhang Z, Yang R, Guan Q, Hou X, Wu Q. | 02/21/2015 |
| These findings implicate miRs as intermediaries in aldosterone signaling in principal cells of the distal kidney nephron. | Aldosterone regulates microRNAs in the cortical collecting duct to alter sodium transport.
Edinger RS, Coronnello C, Bodnar AJ, Labarca M, Bhalla V, LaFramboise WA, Benos PV, Ho J, Johnson JP, Butterworth MB., Free PMC Article | 01/10/2015 |
| miR-335 targets endoderm transcription factors for spatio-temporal gradient formation in the endoderm. | miR-335 promotes mesendodermal lineage segregation and shapes a transcription factor gradient in the endoderm.
Yang D, Lutter D, Burtscher I, Uetzmann L, Theis FJ, Lickert H. | 03/22/2014 |
| miR-335-5p is a novel regulator expressed in oocytes that is involved in cytoskeleton dynamics. | Involvement of microRNA-335-5p in cytoskeleton dynamics in mouse oocytes.
Cui XS, Sun SC, Kang YK, Kim NH. | 11/16/2013 |
| During mESC differentiation, miR-335 upregulation co-operates with the transcriptional repression of Oct4 to facilitate the collapse of the Oct4-Nipp1/Ccnf-PP1-pRb axis, and establishment of a pRb-regulated cell cycle program. | An Oct4-pRb axis, controlled by MiR-335, integrates stem cell self-renewal and cell cycle control.
Schoeftner S, Scarola M, Comisso E, Schneider C, Benetti R. | 10/19/2013 |
| miR-335-5p activates Wnt signaling and promotes osteogenic differentiation by downregulating DKK1. | Effects of miR-335-5p in modulating osteogenic differentiation by specifically downregulating Wnt antagonist DKK1.
Zhang J, Tu Q, Bonewald LF, He X, Stein G, Lian J, Chen J., Free PMC Article | 11/12/2011 |
| This is the first evidence that miR335 controls the proliferation and survival of neural progenitor cells, and behaves as a functional antagonist to miR21 | Competing interactions between micro-RNAs determine neural progenitor survival and proliferation after ethanol exposure: evidence from an ex vivo model of the fetal cerebral cortical neuroepithelium.
Sathyan P, Golden HB, Miranda RC., Free PMC Article | 11/9/2009 |