miR-25-3p ameliorates SAE by targeting the TLR4/NLRP3 axis. | miR-25-3p ameliorates SAE by targeting the TLR4/NLRP3 axis. Luo XY, Ying JH, Wang QS., Free PMC Article | 07/23/2022 |
Effect of Salivary Exosomal miR-25-3p on Periodontitis With Insulin Resistance. | Effect of Salivary Exosomal miR-25-3p on Periodontitis With Insulin Resistance. Byun JS, Lee HY, Tian J, Moon JS, Choi J, Lee SH, Kim YG, Yi HS., Free PMC Article | 03/5/2022 |
Deletion of the miR-25/93/106b cluster induces glomerular deposition of immune complexes and renal fibrosis in mice. | Deletion of the miR-25/93/106b cluster induces glomerular deposition of immune complexes and renal fibrosis in mice. Ma H, Li X, Yu S, Hu Y, Yin M, Zhu F, Xu L, Wang T, Wang H, Li H, Zhao B, Huang Y., Free PMC Article | 02/19/2022 |
Adipose-derived mesenchymal stem cells reduce autophagy in stroke mice by extracellular vesicle transfer of miR-25. | Adipose-derived mesenchymal stem cells reduce autophagy in stroke mice by extracellular vesicle transfer of miR-25. Kuang Y, Zheng X, Zhang L, Ai X, Venkataramani V, Kilic E, Hermann DM, Majid A, Bähr M, Doeppner TR., Free PMC Article | 01/22/2022 |
Inflammation in an Animal Model of Multiple Sclerosis Leads to MicroRNA-25-3p Dysregulation Associated with Inhibition of Pten and Klf4. | Inflammation in an Animal Model of Multiple Sclerosis Leads to MicroRNA-25-3p Dysregulation Associated with Inhibition of Pten and Klf4. Zare-Chahoki A, Ahmadi-Zeidabadi M, Azadarmaki S, Ghorbani S, Noorbakhsh F. | 12/11/2021 |
LncRNA SNHG12 alleviates hypertensive vascular endothelial injury through miR-25-3p/SIRT6 pathway. | LncRNA SNHG12 alleviates hypertensive vascular endothelial injury through miR-25-3p/SIRT6 pathway. Qian W, Zheng ZQ, Nie JG, Liu LJ, Meng XZ, Sun H, Xiao FM, Kang T. | 10/23/2021 |
microRNA-25 as a novel modulator of circadian Period2 gene oscillation. | microRNA-25 as a novel modulator of circadian Period2 gene oscillation. Park I, Kim D, Kim J, Jang S, Choi M, Choe HK, Choe Y, Kim K., Free PMC Article | 10/2/2021 |
A microRNA program regulates the balance between cardiomyocyte hyperplasia and hypertrophy and stimulates cardiac regeneration. | A microRNA program regulates the balance between cardiomyocyte hyperplasia and hypertrophy and stimulates cardiac regeneration. Raso A, Dirkx E, Sampaio-Pinto V, El Azzouzi H, Cubero RJ, Sorensen DW, Ottaviani L, Olieslagers S, Huibers MM, de Weger R, Siddiqi S, Moimas S, Torrini C, Zentillin L, Braga L, Nascimento DS, da Costa Martins PA, van Berlo JH, Zacchigna S, Giacca M, De Windt LJ., Free PMC Article | 08/28/2021 |
miR-25-3p promotes endothelial cell angiogenesis in aging mice via TULA-2/SYK/VEGFR-2 downregulation. | miR-25-3p promotes endothelial cell angiogenesis in aging mice via TULA-2/SYK/VEGFR-2 downregulation. Lian C, Zhao L, Qiu J, Wang Y, Chen R, Liu Z, Cui J, Zhu X, Wen X, Wang S, Wang J., Free PMC Article | 05/1/2021 |
Exosomal miR-25-3p from mesenchymal stem cells alleviates myocardial infarction by targeting pro-apoptotic proteins and EZH2. | Exosomal miR-25-3p from mesenchymal stem cells alleviates myocardial infarction by targeting pro-apoptotic proteins and EZH2. Peng Y, Zhao JL, Peng ZY, Xu WF, Yu GL., Free PMC Article | 04/13/2021 |
miR-25-3p promotes proliferation and inhibits autophagy of renal cells in polycystic kidney mice by regulating ATG14-Beclin 1. | miR-25-3p promotes proliferation and inhibits autophagy of renal cells in polycystic kidney mice by regulating ATG14-Beclin 1. Liu G, Kang X, Guo P, Shang Y, Du R, Wang X, Chen L, Yue R, Kong F., Free PMC Article | 02/2/2021 |
Overexpression of miRNA-25-3p inhibits Notch1 signaling and TGF-beta-induced collagen expression in hepatic stellate cells. | Overexpression of miRNA-25-3p inhibits Notch1 signaling and TGF-β-induced collagen expression in hepatic stellate cells. Genz B, Coleman MA, Irvine KM, Kutasovic JR, Miranda M, Gratte FD, Tirnitz-Parker JEE, Olynyk JK, Calvopina DA, Weis A, Cloonan N, Robinson H, Hill MM, Al-Ejeh F, Ramm GA., Free PMC Article | 10/24/2020 |
miR-25-3p inhibition impairs tumorigenesis and invasion in gastric cancer cells in vitro and in vivo. | miR-25-3p inhibition impairs tumorigenesis and invasion in gastric cancer cells in vitro and in vivo. Ning L, Zhang M, Zhu Q, Hao F, Shen W, Chen D., Free PMC Article | 10/3/2020 |
MicroRNA-25 aggravates Abeta1-42-induced hippocampal neuron injury in Alzheimer's disease by downregulating KLF2 via the Nrf2 signaling pathway in a mouse model. | MicroRNA-25 aggravates Aβ1-42-induced hippocampal neuron injury in Alzheimer's disease by downregulating KLF2 via the Nrf2 signaling pathway in a mouse model. Duan Q, Si E. | 09/19/2020 |
MicroRNA-25-3p regulates osteoclasts through nuclear factor I X. | MicroRNA-25-3p regulates osteoclasts through nuclear factor I X. Huang Y, Ren K, Yao T, Zhu H, Xu Y, Ye H, Chen Z, Lv J, Shen S, Ma J. | 08/22/2020 |
These results show that antagonizing let-7 and increasing levels of miR-25 and miR-124 using miRNA mimics is useful in reprogramming Muller glial cells to retinal neurons in vitro and could help in stimulating regeneration in this system. | MicroRNAs miR-25, let-7 and miR-124 regulate the neurogenic potential of Müller glia in mice. Wohl SG, Hooper MJ, Reh TA., Free PMC Article | 07/18/2020 |
PRC2-Six1-miR-25 signaling axis is involved in heart failure. | Role of the PRC2-Six1-miR-25 signaling axis in heart failure. Oh JG, Jang SP, Yoo J, Lee MA, Lee SH, Lim T, Jeong E, Kho C, Kook H, Hajjar RJ, Park WJ, Jeong D. | 06/27/2020 |
MicroRNA-25 blocks corticosterone-induced VSMC apoptosis by targeting MOAP1 and the p70S6k pathway. | MicroRNA-25 Protects Smooth Muscle Cells against Corticosterone-Induced Apoptosis. Zhang B, Zhang G, Wei T, Yang Z, Tan W, Mo Z, Liu J, Li D, Wei Y, Zhang L, Webster KA, Wei J., Free PMC Article | 08/31/2019 |
MiR-25 promoted the proliferation, differentiation and migration of osteoblasts by upregulating Rac1 expression | MiR-25 promotes proliferation, differentiation and migration of osteoblasts by up-regulating Rac1 expression. Li X, Ji J, Wei W, Liu L. | 09/22/2018 |
miR-25-3p enhances C2C12 cell metabolism by targeting the Akt1 gene. | miR-25-3p, Positively Regulated by Transcription Factor AP-2α, Regulates the Metabolism of C2C12 Cells by Targeting Akt1. Zhang F, Chen K, Tao H, Kang T, Xiong Q, Zeng Q, Liu Y, Jiang S, Chen M., Free PMC Article | 08/18/2018 |
miR-25 and its precursor were significantly decreased in diabetic mice, whereas primary miR-25 levels were significantly increased. miR-25 (primary, precursor, and mature) showed similar trends of regulation in glomerular mesangial cells treated with high glucose or TGF-beta. The SIAH1/HIPK2/MeCP2 axis played a novel role for in suppressing miR-25 processing and thereby upregulating NOX4 in early diabetic nephropathy. | Inhibition of the processing of miR-25 by HIPK2-Phosphorylated-MeCP2 induces NOX4 in early diabetic nephropathy. Oh HJ, Kato M, Deshpande S, Zhang E, Das S, Lanting L, Wang M, Natarajan R., Free PMC Article | 07/14/2018 |
miR-25 has a role in diabetic nephropathy, and experimentally in proteinuria, extracellular matrix accumulation, podocyte foot process effacement, and hypertension with renin-angiotensin system activation | Variations in MicroRNA-25 Expression Influence the Severity of Diabetic Kidney Disease. Liu Y, Li H, Liu J, Han P, Li X, Bai H, Zhang C, Sun X, Teng Y, Zhang Y, Yuan X, Chu Y, Zhao B., Free PMC Article | 12/30/2017 |
miR-25/93 targets NCOA3, an epigenetic factor that maintains basal levels of cGAS expression, leading to repression of cGAS during hypoxia. This allows hypoxic tumour cells to escape immunological responses induced by damage-associated molecular pattern molecules, specifically the release of mitochondrial DNA. | miR-25/93 mediates hypoxia-induced immunosuppression by repressing cGAS. Wu MZ, Cheng WC, Chen SF, Nieh S, O'Connor C, Liu CL, Tsai WW, Wu CJ, Martin L, Lin YS, Wu KJ, Lu LF, Izpisua Belmonte JC., Free PMC Article | 10/28/2017 |
Data indicate that miR-25 is a novel negative regulator of adipocyte differentiation and it suppressed 3T3-L1 adipogenesis by targeting KLF4 and C/EBPalpha, which provides novel insights into the molecular mechanism of miRNA-mediated cellular differentiation. | MiR-25 suppresses 3T3-L1 adipogenesis by directly targeting KLF4 and C/EBPα. Liang WC, Wang Y, Liang PP, Pan XQ, Fu WM, Yeung VS, Lu YF, Wan DC, Tsui SK, Tsang SY, Ma WB, Zhang JF, Waye MM. | 06/28/2016 |
The cell cycle- and insulin-signaling-inhibiting miRNA expression pattern of very small embryonic-like stem cells contributes to their quiescent state. | The cell cycle- and insulin-signaling-inhibiting miRNA expression pattern of very small embryonic-like stem cells contributes to their quiescent state. Maj M, Schneider G, Ratajczak J, Suszynska M, Kucia M, Ratajczak MZ., Free PMC Article | 11/7/2015 |