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    Mir224 microRNA 224 [ Mus musculus (house mouse) ]

    Gene ID: 723894, updated on 9-Dec-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    miR-224-5p Attenuates Allergic Responses in Mice with Allergic Rhinitis by Modulating the Th1/Th2 Response.

    miR-224-5p Attenuates Allergic Responses in Mice with Allergic Rhinitis by Modulating the Th1/Th2 Response.
    Li Y, An R, Wu M, He J, He X., Free PMC Article

    08/1/2024
    MiR-224 ameliorates inflammation and symptoms in mouse model of allergic rhinitis by targeting CDK9.

    MiR-224 ameliorates inflammation and symptoms in mouse model of allergic rhinitis by targeting CDK9.
    Wang S, Wang L, Hu H, Dong P.

    02/12/2022
    microRNAs (miR 9, 124, 155 and 224) transdifferentiate mouse macrophages to neurons.

    microRNAs (miR 9, 124, 155 and 224) transdifferentiate mouse macrophages to neurons.
    Challagundla N, Agrawal-Rajput R.

    09/25/2021
    LncRNA AK087124/miR-224-5p/PTEN axis modulates endothelial cell injury in atherosclerosis through apoptosis and AKT signaling pathway.

    LncRNA AK087124/miR-224-5p/PTEN axis modulates endothelial cell injury in atherosclerosis through apoptosis and AKT signaling pathway.
    Zhai C, Sun Y, Qian G, Pan H, Xie S, Sun Z, Zhang S, Hu H.

    09/11/2021
    A novel inhibitory role of microRNA-224 in particulate matter 2.5-induced asthmatic mice by inhibiting TLR2.

    A novel inhibitory role of microRNA-224 in particulate matter 2.5-induced asthmatic mice by inhibiting TLR2.
    Li P, Wang J, Guo F, Zheng B, Zhang X., Free PMC Article

    05/1/2021
    Overexpression of miR-224-3p alleviates apoptosis from cerebral ischemia reperfusion injury by targeting FIP200.

    Overexpression of miR-224-3p alleviates apoptosis from cerebral ischemia reperfusion injury by targeting FIP200.
    Deng Y, Ma G, Dong Q, Sun X, Liu L, Miao Z, Gao F.

    09/19/2020
    ectopic expression of miR-744 and miR-224 during neural differentiation resulted in downregulation of endogenous Npas4 expression.

    miR-744 and miR-224 Downregulate Npas4 and Affect Lineage Differentiation Potential and Neurite Development During Neural Differentiation of Mouse Embryonic Stem Cells.
    Choy FC, Klarić TS, Koblar SA, Lewis MD.

    03/10/2018
    miR-224 plays an essential role in adipocyte apoptosis caused by TNFalpha through control of NF-kappaB activation via targeting the TANK gene.

    MicroRNA-224-5p regulates adipocyte apoptosis induced by TNFα via controlling NF-κB activation.
    Qi R, Huang J, Wang Q, Liu H, Wang R, Wang J, Yang F.

    11/18/2017
    miR-224 overexpression increases the expression of GFRalpha1 and PLZF, accompanied by the down-regulation of DMRT1 in mouse testes.

    MicroRNA-224 regulates self-renewal of mouse spermatogonial stem cells via targeting DMRT1.
    Cui N, Hao G, Zhao Z, Wang F, Cao J, Yang A., Free PMC Article

    07/8/2017
    Results suggests that miR-224 regulates Ptx3 under normal conditions.

    microRNA-224 regulates Pentraxin 3, a component of the humoral arm of innate immunity, in inner ear inflammation.
    Rudnicki A, Shivatzki S, Beyer LA, Takada Y, Raphael Y, Avraham KB., Free PMC Article

    01/17/2015
    miR-224 may affect ovulation and subsequent embryo development by targeting Ptx3.

    MicroRNA-224 is involved in the regulation of mouse cumulus expansion by targeting Ptx3.
    Yao G, Liang M, Liang N, Yin M, Lü M, Lian J, Wang Y, Sun F.

    08/30/2014
    we show that the 3' untranslated region (3'UTR) of NPAS4 can be targeted by two microRNAs, miR-203 and miR-224 to further regulate its expression.

    Regulation of the neuronal transcription factor NPAS4 by REST and microRNAs.
    Bersten DC, Wright JA, McCarthy PJ, Whitelaw ML.

    03/22/2014
    miR-224 plays different roles on different stages of adipogenesis.

    MiR-224 impairs adipocyte early differentiation and regulates fatty acid metabolism.
    Peng Y, Xiang H, Chen C, Zheng R, Chai J, Peng J, Jiang S.

    02/15/2014
    results showed that both the tumor suppressor gene p53 and NF-kappaB p65 subunit suppressed the TGF-beta1-induced increase in pri-miR-224 expression in follicular granulosa cells

    Transcriptional cooperation between p53 and NF-κB p65 regulates microRNA-224 transcription in mouse ovarian granulosa cells.
    Liang M, Yao G, Yin M, Lü M, Tian H, Liu L, Lian J, Huang X, Sun F.

    12/14/2013
    In metastatic colorectal cancer cells, reduced levels of miR-221* and miR-224 increase levels of MBD2, thereby decreasing expression of the metastasis suppressor maspin.

    Decreased levels of miR-224 and the passenger strand of miR-221 increase MBD2, suppressing maspin and promoting colorectal tumor growth and metastasis in mice.
    Yuan K, Xie K, Fox J, Zeng H, Gao H, Huang C, Wu M., Free PMC Article

    12/14/2013
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