| MiR-100-5p-rich small extracellular vesicles from activated neuron to aggravate microglial activation and neuronal activity after stroke. | MiR-100-5p-rich small extracellular vesicles from activated neuron to aggravate microglial activation and neuronal activity after stroke.
Xin D, Li T, Zhao Y, Guo X, Gai C, Jiang Z, Yu S, Cheng J, Song Y, Cheng Y, Luo Q, Gu B, Liu D, Wang Z., Free PMC Article | 10/11/2024 |
| Macrophage-derived mir-100-5p orchestrates synovial proliferation and inflammation in rheumatoid arthritis through mTOR signaling. | Macrophage-derived mir-100-5p orchestrates synovial proliferation and inflammation in rheumatoid arthritis through mTOR signaling.
Liu H, Chen Y, Huang Y, Wei L, Ran J, Li Q, Tian Y, Luo Z, Yang L, Liu H, Yin G, Xie Q., Free PMC Article | 05/10/2024 |
| Extracellular vesicles secreted from mesenchymal stem cells ameliorate renal ischemia reperfusion injury by delivering miR-100-5p targeting FKBP5/AKT axis. | Extracellular vesicles secreted from mesenchymal stem cells ameliorate renal ischemia reperfusion injury by delivering miR-100-5p targeting FKBP5/AKT axis.
Chen G, Li X, Zhou X, Li Y, Yu H, Peng X, Bai X, Zhang C, Feng Z, Mei Y, Li L, Liu Y, Gou X, Jiang Y., Free PMC Article | 03/22/2024 |
| miR-100a-5p-enriched exosomes derived from mesenchymal stem cells enhance the anti-oxidant effect in a Parkinson's disease model via regulation of Nox4/ROS/Nrf2 signaling. | miR-100a-5p-enriched exosomes derived from mesenchymal stem cells enhance the anti-oxidant effect in a Parkinson's disease model via regulation of Nox4/ROS/Nrf2 signaling.
He S, Wang Q, Chen L, He YJ, Wang X, Qu S., Free PMC Article | 10/28/2023 |
| miR-100-5p activation of the autophagy response through inhibiting the mTOR pathway and suppression of cerebral infarction progression in mice. | miR-100-5p activation of the autophagy response through inhibiting the mTOR pathway and suppression of cerebral infarction progression in mice.
Cao X, Zhang X, Chen J, Sun Q, Sun Y, Lin N, Liu X., Free PMC Article | 09/11/2023 |
| microRNA-100 shuttled by human umbilical cord MSC-secreted extracellular vesicles induces endometriosis by inhibiting HS3ST2. | microRNA-100 shuttled by human umbilical cord MSC-secreted extracellular vesicles induces endometriosis by inhibiting HS3ST2.
Zhang F, Li F, Lu J. | 01/7/2023 |
| MicroRNA-100-5p and microRNA-298-5p released from apoptotic cortical neurons are endogenous Toll-like receptor 7/8 ligands that contribute to neurodegeneration. | MicroRNA-100-5p and microRNA-298-5p released from apoptotic cortical neurons are endogenous Toll-like receptor 7/8 ligands that contribute to neurodegeneration.
Wallach T, Mossmann ZJ, Szczepek M, Wetzel M, Machado R, Raden M, Miladi M, Kleinau G, Krüger C, Dembny P, Adler D, Zhai Y, Kumbol V, Dzaye O, Schüler J, Futschik M, Backofen R, Scheerer P, Lehnardt S., Free PMC Article | 04/16/2022 |
| Inhibition of miRNA-100 facilitates bone regeneration defects of mesenchymal stem cells in osteoporotic mice through the protein kinase B pathway. | Inhibition of miRNA-100 facilitates bone regeneration defects of mesenchymal stem cells in osteoporotic mice through the protein kinase B pathway.
Dai Z, Wei G., Free PMC Article | 03/19/2022 |
| MiR-100 overexpression attenuates high fat diet induced weight gain, liver steatosis, hypertriglyceridemia and development of metabolic syndrome in mice. | MiR-100 overexpression attenuates high fat diet induced weight gain, liver steatosis, hypertriglyceridemia and development of metabolic syndrome in mice.
Smolka C, Schlösser D, Hohnloser C, Bemtgen X, Jänich C, Schneider L, Martin J, Pfeifer D, Moser M, Hasselblatt P, Bode C, Grundmann S, Pankratz F., Free PMC Article | 01/22/2022 |
| Cardiomyocyte-specific miR-100 overexpression preserves heart function under pressure overload in mice and diminishes fatty acid uptake as well as ROS production by direct suppression of Nox4 and CD36. | Cardiomyocyte-specific miR-100 overexpression preserves heart function under pressure overload in mice and diminishes fatty acid uptake as well as ROS production by direct suppression of Nox4 and CD36.
Smolka C, Schlösser D, Koentges C, Tarkhnishvili A, Gorka O, Pfeifer D, Bemtgen X, Asmussen A, Groß O, Diehl P, Moser M, Bode C, Bugger H, Grundmann S, Pankratz F. | 11/13/2021 |
| Mechanosensitive miR-100 coordinates TGFbeta and Wnt signaling in osteocytes during fluid shear stress. | Mechanosensitive miR-100 coordinates TGFβ and Wnt signaling in osteocytes during fluid shear stress.
Dole NS, Yoon J, Monteiro DA, Yang J, Mazur CM, Kaya S, Belair CD, Alliston T., Free PMC Article | 10/16/2021 |
| Neural progenitor cell-derived nanovesicles promote hair follicle growth via miR-100. | Neural progenitor cell-derived nanovesicles promote hair follicle growth via miR-100.
Cao L, Tian T, Huang Y, Tao S, Zhu X, Yang M, Gu J, Feng G, Ma Y, Xia R, Xu W, Wang L., Free PMC Article | 09/18/2021 |
| The decreased circular RNA hsa_circ_0072309 promotes cell apoptosis of ischemic stroke by sponging miR-100. | The decreased circular RNA hsa_circ_0072309 promotes cell apoptosis of ischemic stroke by sponging miR-100.
Zhao Y, Li J, Li J, Xu L, Lian W. | 04/3/2021 |
| In a LDL-receptor-deficient atherosclerotic mouse model, inhibition of miR-100 resulted in enhanced plaque lesion formation and a higher macrophage content of the plaque. Systemic miR-100 replacement therapy had protective effects and attenuated atherogenesis, decreasing plaque area by 45%. | MicroRNA-100 Suppresses Chronic Vascular Inflammation by Stimulation of Endothelial Autophagy.
Pankratz F, Hohnloser C, Bemtgen X, Jaenich C, Kreuzaler S, Hoefer I, Pasterkamp G, Mastroianni J, Zeiser R, Smolka C, Schneider L, Martin J, Juschkat M, Helbing T, Moser M, Bode C, Grundmann S. | 07/6/2019 |
| ectopic down-regulation of IGF1R reversed the protective effect of miR-100 down-regulation on H2O2-induced apoptosis, revealing that miR-100 regulates cardiomyocyte apoptosis through the association of IGF1R. | Downregulation of microRNA-100 protects H2O2-induced apoptosis in neonatal cardiomyocytes.
Chen A, Li G, Chen L, Guo J, Liu Y., Free PMC Article | 05/28/2016 |
| specific inhibition of mmu-miR-100-5p significantly enhanced expression of Il6, Ptgs1/2 and Tlr4 mRNA | MicroRNA-100-5p indirectly modulates the expression of Il6, Ptgs1/2 and Tlr4 mRNA in the mouse follicular dendritic cell-like cell line, FL-Y.
Aungier SR, Ohmori H, Clinton M, Mabbott NA., Free PMC Article | 02/14/2015 |
| members of miR-99 family (miR-99a, miR-99b, miR-100) were expressed during dermal wound healing. | MicroRNA-99 family targets AKT/mTOR signaling pathway in dermal wound healing.
Jin Y, Tymen SD, Chen D, Fang ZJ, Zhao Y, Dragas D, Dai Y, Marucha PT, Zhou X., Free PMC Article | 01/11/2014 |
| MiR-100 modulates proliferation, tube formation, and sprouting activity of endothelial cells and migration of vascular smooth muscle cells and functions as an endogenous repressor of mammalian target of rapamycin (mTOR). | MicroRNA-100 regulates neovascularization by suppression of mammalian target of rapamycin in endothelial and vascular smooth muscle cells.
Grundmann S, Hans FP, Kinniry S, Heinke J, Helbing T, Bluhm F, Sluijter JP, Hoefer I, Pasterkamp G, Bode C, Moser M. | 05/21/2011 |