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    Mir377 microRNA 377 [ Mus musculus (house mouse) ]

    Gene ID: 723857, updated on 9-Dec-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    miR-377-3p Regulates Hippocampal Neurogenesis via the Zfp462-Pbx1 Pathway and Mediates Anxiety-Like Behaviors in Prenatal Hypoxic Offspring.

    miR-377-3p Regulates Hippocampal Neurogenesis via the Zfp462-Pbx1 Pathway and Mediates Anxiety-Like Behaviors in Prenatal Hypoxic Offspring.
    Wang B, Zhu Y, Wei B, Zeng H, Zhang P, Li L, Wang H, Wu X, Zheng Y, Sun M.

    04/1/2024
    Circ-C16orf62 Regulates Oxidized low-density Lipoprotein-induced Apoptosis, Inflammation, Oxidative Stress and Cholesterol Accumulation of Macrophages via Mediating RAB22A Expression by Targeting miR-377.

    Circ-C16orf62 Regulates Oxidized low-density Lipoprotein-induced Apoptosis, Inflammation, Oxidative Stress and Cholesterol Accumulation of Macrophages via Mediating RAB22A Expression by Targeting miR-377.
    Yin X, Chen H, Sun G, Xu Y, Wang L.

    11/15/2023
    CircRNA Circ_0000118 Regulates Malignancy of Cervical Cancer Cells by Regulating miR-211-5p/miR-377-3p/AKT2 Axis.

    CircRNA Circ_0000118 Regulates Malignancy of Cervical Cancer Cells by Regulating miR-211-5p/miR-377-3p/AKT2 Axis.
    Wu L, Xiao H, Hong Y, Xie M, Yu Y, Jiang L., Free PMC Article

    10/28/2023
    SNHG1 alleviates the oxidative stress and inflammatory response in traumatic brain injury through regulating miR-377-3p/DUSP1 axis.

    SNHG1 alleviates the oxidative stress and inflammatory response in traumatic brain injury through regulating miR-377-3p/DUSP1 axis.
    Jiao W, Jiang L, Zhang Y.

    01/11/2023
    The Overexpression of miR-377 Aggravates Sepsis-Induced Myocardial Hypertrophy by Binding to Rcan2 and Mediating CaN Activity.

    The Overexpression of miR-377 Aggravates Sepsis-Induced Myocardial Hypertrophy by Binding to Rcan2 and Mediating CaN Activity.
    Wang S, Wang G, Dong L, Liu X, Pan W, Han J, Lu Y., Free PMC Article

    10/29/2022
    Downregulation of mmu_circ_0000943 ameliorates renal ischemia reperfusion-triggered inflammation and oxidative stress via regulating mmu-miR-377-3p/Egr2 axis.

    Downregulation of mmu_circ_0000943 ameliorates renal ischemia reperfusion-triggered inflammation and oxidative stress via regulating mmu-miR-377-3p/Egr2 axis.
    Huang T, Gao Y, Cao Y, Wang Q, Dong Z.

    07/9/2022
    MiR-377-3p inhibits atherosclerosis-associated vascular smooth muscle cell proliferation and migration via targeting neuropilin2.

    MiR-377-3p inhibits atherosclerosis-associated vascular smooth muscle cell proliferation and migration via targeting neuropilin2.
    Wang H, Wei Z, Li H, Guan Y, Han Z, Wang H, Liu B., Free PMC Article

    04/3/2021
    lncRNA NEAT1 facilitated the survival and angiogenesis of OGD-induced BMECs via targeting miR-377 and promoting the expression of VEGFA, SIRT1, and BCL-XL.

    LncRNA NEAT1 facilitates survival and angiogenesis in oxygen-glucose deprivation (OGD)-induced brain microvascular endothelial cells (BMECs) via targeting miR-377 and upregulating SIRT1, VEGFA, and BCL-XL.
    Zhou ZW, Zheng LJ, Ren X, Li AP, Zhou WS.

    06/13/2020
    miR-377 effectively mediated the expression of the Syk gene in vitro and in vivo experiments.

    MiR-377 mediates the expression of Syk to attenuate atherosclerosis lesion development in ApoE(-/-) mice.
    Guo Y, Huang S, Ma Y, Zhang J, Wen Y, Zhou L, Yuan G, Cheng J.

    02/8/2020
    It is concluded that miR-377 upregulates GPIHBP1 expression, increases the LPL binding to GPIHBP1, and reduces plasma triglyceride levels, likely through targeting DNMT1, inhibiting atherosclerosis in ApoE-KO mice.

    MicroRNA-377 Inhibits Atherosclerosis by Regulating Triglyceride Metabolism Through the DNA Methyltransferase 1 in Apolipoprotein E-Knockout Mice.
    Chen LY, Xia XD, Zhao ZW, Gong D, Ma XF, Yu XH, Zhang Q, Wang SQ, Dai XY, Zheng XL, Zhang DW, Yin WD, Tang CK.

    11/16/2019
    renal ischemia/reperfusion (I/R) induced miR-377 expression, which upregulated VEGF expression to attenuate renal I/R-induced oxidative stress and inflammation, and finally ameliorated renal dysfunction.

    The protective effect of miR-377 inhibitor against renal ischemia-reperfusion injury through inhibition of inflammation and oxidative stress via a VEGF-dependent mechanism in mice.
    Liu Z, Yang Q, Wei Q, Chang Y, Qu M, Yu L.

    05/4/2019
    The expression of TUG1 antagonized the effect of miR-377 on the downregulation of its target PPARgamma and inhibited extracellular matrix accumulation, including PAI-1, TGF-beta1, fibronectin (FN) and collagen IV (Col IV), induced by high glucose. LncRNA TUG1 acts as an endogenous sponge of miR-377 and downregulates miR-377 expression levels, and thereby relieving the inhibition of its target gene PPARgamma and allevia...

    Long noncoding RNA TUG1 alleviates extracellular matrix accumulation via mediating microRNA-377 targeting of PPARĪ³ in diabetic nephropathy.
    Duan LJ, Ding M, Hou LJ, Cui YT, Li CJ, Yu DM.

    06/10/2017
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