| Lower levels of TRAF1 in Brodmann's area 24, but not 46, in bipolar disorders are not detectable in major depressive disorders. | Lower levels of TRAF1 in Brodmann's area 24, but not 46, in bipolar disorders are not detectable in major depressive disorders.
Dean B, Seymour N, Gibbons A. | 05/24/2024 |
| Association between TRAF1/C5 Gene Polymorphisms and IgA Vasculitis in Chinese Children. | Association between TRAF1/C5 Gene Polymorphisms and IgA Vasculitis in Chinese Children.
Yu M, Yang Y, Zhang J, Liu R, Huang L, Wu J, Kang Z, Zhou J, Yang Z. | 03/25/2024 |
| Cutting Edge: Negative Regulation of Inflammasome Activation by TRAF1 Can Limit Gout. | Cutting Edge: Negative Regulation of Inflammasome Activation by TRAF1 Can Limit Gout.
Mirzaesmaeili A, Zangiabadi S, Raspanti J, Akram A, Inman RD, Abdul-Sater AA. | 03/11/2023 |
| Knockdown of circ_0038467 alleviates lipopolysaccharides-induced 16HBE cell injury by regulating the miR-545-3p/TRAF1 axis in neonatal pneumonia. | Knockdown of circ_0038467 alleviates lipopolysaccharides-induced 16HBE cell injury by regulating the miR-545-3p/TRAF1 axis in neonatal pneumonia.
Xia F, Yang L, Zhu X. | 12/17/2022 |
| N(6)-methyladenosine-modified TRAF1 promotes sunitinib resistance by regulating apoptosis and angiogenesis in a METTL14-dependent manner in renal cell carcinoma. | N(6)-methyladenosine-modified TRAF1 promotes sunitinib resistance by regulating apoptosis and angiogenesis in a METTL14-dependent manner in renal cell carcinoma.
Chen Y, Lu Z, Qi C, Yu C, Li Y, Huan W, Wang R, Luo W, Shen D, Ding L, Ren L, Xie H, Xue D, Wang M, Ni K, Xia L, Qian J, Li G., Free PMC Article | 05/14/2022 |
| FXR1 can bind with the CFIm25/CFIm68 complex and promote the progression of urothelial carcinoma of the bladder by stabilizing TRAF1 mRNA. | FXR1 can bind with the CFIm25/CFIm68 complex and promote the progression of urothelial carcinoma of the bladder by stabilizing TRAF1 mRNA.
Deng M, Wang N, Li Z, Chen R, Duan J, Peng Y, Wu Z, Zhang Z, Jiang L, Zheng X, Xie D, Wei W, Liu Z, Zhou F., Free PMC Article | 04/16/2022 |
| A genetic variant in the TRAF1/C5 gene lead susceptibility to active pulmonary tuberculosis by decreased TNF-alpha levels. | A genetic variant in the TRAF1/C5 gene lead susceptibility to active pulmonary tuberculosis by decreased TNF-α levels.
Souza de Lima D, Fadoul de Brito C, Cavalcante Barbosa AR, Brasil de Andrade Figueira M, Maciel Bonet JC, Walzer J, Ramasawmy R, Ogusku MM, Sadahiro A, Boechat AL. | 09/18/2021 |
| TRAF1 suppresses antifungal immunity through CXCL1-mediated neutrophil recruitment during Candida albicans intradermal infection. | TRAF1 suppresses antifungal immunity through CXCL1-mediated neutrophil recruitment during Candida albicans intradermal infection.
Bai W, Wang Q, Deng Z, Li T, Xiao H, Wu Z., Free PMC Article | 07/10/2021 |
| Weighted gene co-expression network analysis identifies RHOH and TRAF1 as key candidate genes for psoriatic arthritis. | Weighted gene co-expression network analysis identifies RHOH and TRAF1 as key candidate genes for psoriatic arthritis.
He J, Tang J, Feng Q, Li T, Wu K, Yang K, Jia D, Xia Q. | 06/19/2021 |
| TRAF4, a new substrate of SIAH1, participates in chemotherapy resistance of breast cancer cell by counteracting SIAH1-mediated downregulation of beta-catenin. | TRAF4, a new substrate of SIAH1, participates in chemotherapy resistance of breast cancer cell by counteracting SIAH1-mediated downregulation of β-catenin.
Ren H, Mi X, Zhao P, Zhao X, Wei N, Huang H, Meng Z, Kou J, Sun M, Liu Y, Zhang H, Yang J, Li W, Li H. | 01/9/2021 |
| Association of TRAF1/C5 Locus Polymorphisms with the risk of developing severe neurocysticercosis in the Mexican population. | Association of TRAF1/C5 Locus Polymorphisms with Epilepsy and Clinical Traits in Mexican Patients with Neurocysticercosis.
Villegas M, Sciutto E, Rosetti M, Fleury A, Fragoso G., Free PMC Article | 02/22/2020 |
| Study review the role of TRAF1 as a positive and negative regulator in different signaling pathways and the role of TRAF1 in human disease. | TRAF1 Signaling in Human Health and Disease.
Edilova MI, Abdul-Sater AA, Watts TH., Free PMC Article | 11/30/2019 |
| The authors found that tumor necrosis factor receptor-associated factor 2 (TRAF2), as well as TRAF1 and 3, directly binds to the active caspase-2 dimer. | Dimer-specific immunoprecipitation of active caspase-2 identifies TRAF proteins as novel activators.
Robeson AC, Lindblom KR, Wojton J, Kornbluth S, Matsuura K., Free PMC Article | 03/30/2019 |
| The data suggest that miR-483 is a colorectal cancer suppressor which could inhibit cell proliferation and migration, possibly via targeting TRAF1. | Mir-483 inhibits colon cancer cell proliferation and migration by targeting TRAF1.
Niu ZY, Li WL, Jiang DL, Li YS, Xie XJ. | 01/5/2019 |
| Results showed that TRAF1 was frequently upregulated in NSCLC tissues compared with adjacent non-cancerous lung tissues. TRAF1 expression was positively associated with NSCLC lymphatic metastasis and histological grade and was negatively associated with overall patient survival. | TNF receptor-associated factor 1 as a biomarker for assessment of non-small cell lung cancer metastasis and overall survival.
Wen X, Wang B, Feng T, Yuan W, Zhou J, Fang T. | 12/29/2018 |
| TRAF1, CTGF, and CX3CL1 genes are hypomethylated in osteoarthritis | Genome-wide DNA methylation analysis of articular chondrocytes identifies TRAF1, CTGF, and CX3CL1 genes as hypomethylated in osteoarthritis.
Zhao L, Wang Q, Zhang C, Huang C. | 10/13/2018 |
| Authors demonstrated that TRAF1 expression had no significant prognostic value for GBM. | Prognostic Significance of TNFR-Associated Factor 1 and 2 (TRAF1 and TRAF2) in Glioblastoma.
Zhang W, Sun Y, Liu L, Li Z., Free PMC Article | 05/26/2018 |
| TRAF1 functions as a positive regulator of insulin resistance, inflammation, and hepatic steatosis dependent on the activation of ASK1-P38/JNK axis. | Targeting hepatic TRAF1-ASK1 signaling to improve inflammation, insulin resistance, and hepatic steatosis.
Xiang M, Wang PX, Wang AB, Zhang XJ, Zhang Y, Zhang P, Mei FH, Chen MH, Li H. | 02/17/2018 |
| The structure reveals both similarities and differences with other TRAF family members, which may be functionally relevant to TRAFs. The authors also found that the TRAF-N coiled-coil domain of TRAF1 is critical for the trimer formation and stability of the protein. | Crystal structure of TRAF1 TRAF domain and its implications in the TRAF1-mediated intracellular signaling pathway.
Kim CM, Choi JY, Bhat EA, Jeong JH, Son YJ, Kim S, Park HH., Free PMC Article | 02/10/2018 |
| this study reveals an unexpected role for TRAF1 in negatively regulating Toll-like receptor signaling, providing a mechanistic explanation for the increased inflammation seen with a rheumatoid arthritis-associated single-nucleotide polymorphism in the TRAF1 gene | The signaling adaptor TRAF1 negatively regulates Toll-like receptor signaling and this underlies its role in rheumatic disease.
Abdul-Sater AA, Edilova MI, Clouthier DL, Mbanwi A, Kremmer E, Watts TH. | 07/1/2017 |
| H. pylori infection significantly inhibits the cleavage of TRAF1 via a CagA-dependent mechanism, which would increase the relative amounts of full-length TRAF1 and exert an antiapoptotic effect on H. pylori-infected cells. | Helicobacter pylori inhibits the cleavage of TRAF1 via a CagA-dependent mechanism.
Wan XK, Yuan SL, Wang YC, Tao HX, Jiang W, Guan ZY, Cao C, Liu CJ., Free PMC Article | 06/10/2017 |
| Alleles of rs2416804 in TRAF1 were identified as being linked and associated with carotid intima-media thickness. | Linkage and Association Analysis Identifies TRAF1 Influencing Common Carotid Intima-Media Thickness.
Heßler N, Geisel MH, Coassin S, Erbel R, Heilmann S, Hennig F, Hoffmann B, Jöckel KH, Moebus S, Moskau-Hartmann S, Nürnberg G, Nürnberg P, Vens M, Klockgether T, Kronenberg F, Scherag A, Ziegler A. | 06/10/2017 |
| Molecular basis for TANK recognition by TRAF1 revealed by the crystal structure of TRAF1/TANK complex has been reported. | Molecular basis for TANK recognition by TRAF1 revealed by the crystal structure of TRAF1/TANK complex.
Kim CM, Jeong JH, Son YJ, Choi JH, Kim S, Park HH. | 05/20/2017 |
| Single nucleotide polymorphisms (SNP) in angiotensin II receptor, type 1 (AGTR1), transcription factor AP-2 beta (TFAP2B), and tumor necrosis factor receptor-associated factor 1 (TRAF1) have been reported to be associated with the incidence of PDA in preterm infants. | Single nucleotide polymorphisms in AGTR1, TFAP2B, and TRAF1 are not associated with the incidence of patent ductus arteriosus in Japanese preterm infants.
Kawase K, Sugiura T, Nagaya Y, Yamada T, Sugimoto M, Ito K, Togawa T, Nagasaki R, Kato T, Kouwaki M, Koyama N, Saitoh S. | 04/8/2017 |
| TRAF1 plays a crucial role in the pathogenesis of autoantibodies and may serve as a serologic inflammatory marker of disease activity in rheumatoid arthritis patients. | Increased serum levels of tumor necrosis factor receptor-associated factor 1 (TRAF1) correlate with disease activity and autoantibodies in rheumatoid arthritis.
Cheng T, Sun X, Wu J, Wang M, Eisenberg RA, Chen Z. | 02/18/2017 |