| Effects of the Nonstructural Protein-Nucleolar and Coiled-Body Phosphoprotein 1 Protein Interaction on rRNA Synthesis Through Telomeric Repeat-Binding Factor 2 Regulation Under Nucleolar Stress. | Effects of the Nonstructural Protein-Nucleolar and Coiled-Body Phosphoprotein 1 Protein Interaction on rRNA Synthesis Through Telomeric Repeat-Binding Factor 2 Regulation Under Nucleolar Stress.
Zhang M, Zeng Y, Wang F, Feng H, Liu Q, Li F, Zhao S, Zhao J, Liu Z, Zheng F, Liu H. | 10/25/2024 |
| TRF2-RAP1 represses RAD51-dependent homology-directed telomere repair by promoting BLM-mediated D-loop unwinding and inhibiting BLM-DNA2-dependent 5'-end resection. | TRF2-RAP1 represses RAD51-dependent homology-directed telomere repair by promoting BLM-mediated D-loop unwinding and inhibiting BLM-DNA2-dependent 5'-end resection.
Liang F, Rai R, Sodeinde T, Chang S., Free PMC Article | 10/9/2024 |
| Binding of the TRF2 iDDR motif to RAD50 highlights a convergent evolutionary strategy to inactivate MRN at telomeres. | Binding of the TRF2 iDDR motif to RAD50 highlights a convergent evolutionary strategy to inactivate MRN at telomeres.
Khayat F, Alshmery M, Pal M, Oliver AW, Bianchi A., Free PMC Article | 08/21/2024 |
| miR-29b-1-5p exacerbates myocardial injury induced by sepsis in a mouse model by targeting TERF2. | miR-29b-1-5p exacerbates myocardial injury induced by sepsis in a mouse model by targeting TERF2.
Jiang Y, Xu J, Zeng H, Lin Z, Yi Q, Guo J, Xiao F., Free PMC Article | 05/1/2024 |
| The novel TERF2::PDGFRB fusion gene enhances tumorigenesis via PDGFRB/STAT5 signalling pathways and sensitivity to TKI in ph-like ALL. | The novel TERF2::PDGFRB fusion gene enhances tumorigenesis via PDGFRB/STAT5 signalling pathways and sensitivity to TKI in ph-like ALL.
Xu GF, Zeng Z, Zhang ZB, Zhang XM, Wang M, Xiao Q, Li J, Xie XQ, He S, Fu HH, Liu Y, Yang ZL, Chen Y, Shi J, Wang B, Qiu HY, Zhou Q, Liu Y, Chen SN., Free PMC Article | 03/12/2024 |
| The shelterin component TRF2 mediates columnar stacking of human telomeric chromatin. | The shelterin component TRF2 mediates columnar stacking of human telomeric chromatin.
Wong SY, Soman A, Korolev N, Surya W, Chen Q, Shum W, van Noort J, Nordenskiöld L., Free PMC Article | 01/11/2024 |
| The telomeric protein TERF2/TRF2 impairs HMGB1-driven autophagy. | The telomeric protein TERF2/TRF2 impairs HMGB1-driven autophagy.
Iachettini S, Ciccarone F, Maresca C, D' Angelo C, Petti E, Di Vito S, Ciriolo MR, Zizza P, Biroccio A., Free PMC Article | 06/7/2023 |
| Phosphorylation of TRF2 promotes its interaction with TIN2 and regulates DNA damage response at telomeres. | Phosphorylation of TRF2 promotes its interaction with TIN2 and regulates DNA damage response at telomeres.
Storchova R, Palek M, Palkova N, Veverka P, Brom T, Hofr C, Macurek L., Free PMC Article | 02/28/2023 |
| TRF2 rescues telomere attrition and prolongs cell survival in Duchenne muscular dystrophy cardiomyocytes derived from human iPSCs. | TRF2 rescues telomere attrition and prolongs cell survival in Duchenne muscular dystrophy cardiomyocytes derived from human iPSCs.
Eguchi A, Gonzalez AFGS, Torres-Bigio SI, Koleckar K, Birnbaum F, Zhang JZ, Wang VY, Wu JC, Artandi SE, Blau HM., Free PMC Article | 02/11/2023 |
| In Vitro Characterization of the Physical Interactions between the Long Noncoding RNA TERRA and the Telomeric Proteins TRF1 and TRF2. | In Vitro Characterization of the Physical Interactions between the Long Noncoding RNA TERRA and the Telomeric Proteins TRF1 and TRF2.
Abreu PL, Lee YW, Azzalin CM., Free PMC Article | 10/8/2022 |
| TRF2 inhibition rather than telomerase disruption drives CD4T cell dysfunction during chronic viral infection. | TRF2 inhibition rather than telomerase disruption drives CD4T cell dysfunction during chronic viral infection.
Nguyen LNT, Nguyen LN, Zhao J, Schank M, Dang X, Cao D, Khanal S, Wu XY, Zhang Y, Zhang J, Ning S, Wang L, El Gazzar M, Moorman JP, Yao ZQ., Free PMC Article | 07/16/2022 |
| TRF2 cooperates with CTCF for controlling the oncomiR-193b-3p in colorectal cancer. | TRF2 cooperates with CTCF for controlling the oncomiR-193b-3p in colorectal cancer.
Dinami R, Petti E, Porru M, Rizzo A, Ganci F, Sacconi A, Ostano P, Chiorino G, Trusolino L, Blandino G, Ciliberto G, Zizza P, Biroccio A. | 04/30/2022 |
| Compartmentalization of telomeres through DNA-scaffolded phase separation. | Compartmentalization of telomeres through DNA-scaffolded phase separation.
Jack A, Kim Y, Strom AR, Lee DSW, Williams B, Schaub JM, Kellogg EH, Finkelstein IJ, Ferro LS, Yildiz A, Brangwynne CP., Free PMC Article | 02/12/2022 |
| TRF2 recruits nucleolar protein TCOF1 to coordinate telomere transcription and replication. | TRF2 recruits nucleolar protein TCOF1 to coordinate telomere transcription and replication.
Nie X, Xiao D, Ge Y, Xie Y, Zhou H, Zheng T, Li X, Liu H, Huang H, Zhao Y., Free PMC Article | 01/22/2022 |
| TRF2 promotes dynamic and stepwise looping of POT1 bound telomeric overhang. | TRF2 promotes dynamic and stepwise looping of POT1 bound telomeric overhang.
Paul T, Liou W, Cai X, Opresko PL, Myong S., Free PMC Article | 01/15/2022 |
| TRF2-mediated ORC recruitment underlies telomere stability upon DNA replication stress. | TRF2-mediated ORC recruitment underlies telomere stability upon DNA replication stress.
Higa M, Matsuda Y, Fujii J, Sugimoto N, Yoshida K, Fujita M., Free PMC Article | 01/15/2022 |
| Increase in lamin B1 promotes telomere instability by disrupting the shelterin complex in human cells. | Increase in lamin B1 promotes telomere instability by disrupting the shelterin complex in human cells.
Pennarun G, Picotto J, Etourneaud L, Redavid AR, Certain A, Gauthier LR, Fontanilla-Ramirez P, Busso D, Chabance-Okumura C, Thézé B, Boussin FD, Bertrand P., Free PMC Article | 12/18/2021 |
| Abnormal function of telomere protein TRF2 induces cell mutation and the effects of environmental tumorpromoting factors (Review). | Abnormal function of telomere protein TRF2 induces cell mutation and the effects of environmental tumor‑promoting factors (Review).
Wang Z, Wu X., Free PMC Article | 12/4/2021 |
| Structure, dynamics, and regulation of TRF1-TIN2-mediated trans- and cis-interactions on telomeric DNA. | Structure, dynamics, and regulation of TRF1-TIN2-mediated trans- and cis-interactions on telomeric DNA.
Pan H, Kaur P, Barnes R, Detwiler AC, Sanford SL, Liu M, Xu P, Mahn C, Tang Q, Hao P, Bhattaram D, You C, Gu X, Lu W, Piehler J, Xu G, Weninger K, Riehn R, Opresko PL, Wang H., Free PMC Article | 11/22/2021 |
| TRF2 Mediates Replication Initiation within Human Telomeres to Prevent Telomere Dysfunction. | TRF2 Mediates Replication Initiation within Human Telomeres to Prevent Telomere Dysfunction.
Drosopoulos WC, Deng Z, Twayana S, Kosiyatrakul ST, Vladimirova O, Lieberman PM, Schildkraut CL., Free PMC Article | 11/13/2021 |
| Morphine treatment is associated with diminished telomere length together with down-regulated TERT and TERF2 mRNA levels. | Morphine treatment is associated with diminished telomere length together with down-regulated TERT and TERF2 mRNA levels.
Darvishi FZ, Saadat M. | 10/30/2021 |
| Mitochondrial function in skeletal myofibers is controlled by a TRF2-SIRT3 axis over lifetime. | Mitochondrial function in skeletal myofibers is controlled by a TRF2-SIRT3 axis over lifetime.
Robin JD, Jacome Burbano MS, Peng H, Croce O, Thomas JL, Laberthonniere C, Renault V, Lototska L, Pousse M, Tessier F, Bauwens S, Leong W, Sacconi S, Schaeffer L, Magdinier F, Ye J, Gilson E., Free PMC Article | 05/15/2021 |
| The Long Linker Region of Telomere-Binding Protein TRF2 Is Responsible for Interactions with Lamins. | The Long Linker Region of Telomere-Binding Protein TRF2 Is Responsible for Interactions with Lamins.
Travina AO, Ilicheva NV, Mittenberg AG, Shabelnikov SV, Kotova AV, Podgornaya OI., Free PMC Article | 04/24/2021 |
| Alternative lengthening of telomeres is a self-perpetuating process in ALT-associated PML bodies. | Alternative lengthening of telomeres is a self-perpetuating process in ALT-associated PML bodies.
Zhang JM, Genois MM, Ouyang J, Lan L, Zou L., Free PMC Article | 03/20/2021 |
| TRF2 and VEGF-A: an unknown relationship with prognostic impact on survival of colorectal cancer patients. | TRF2 and VEGF-A: an unknown relationship with prognostic impact on survival of colorectal cancer patients.
Dinami R, Porru M, Amoreo CA, Sperduti I, Mottolese M, Buglioni S, Marinelli D, Maugeri-Saccà M, Sacconi A, Blandino G, Leonetti C, Di Rocco G, Verdina A, Spinella F, Fiorentino F, Ciliberto G, Biroccio A, Zizza P., Free PMC Article | 02/6/2021 |