| TCF12-regulated GRB7 facilitates the HER2+ breast cancer progression by activating Notch1 signaling pathway. | TCF12-regulated GRB7 facilitates the HER2+ breast cancer progression by activating Notch1 signaling pathway.
Wang G, Wu Y, Su Y, Qu N, Chen B, Zhou D, Yuan L, Yin M, Liu M, Zhou W., Free PMC Article | 09/16/2024 |
| Lncrna CASC15 Activated By TCF12 Promote Colorectal Cancer Progression via EMT. | Lncrna CASC15 Activated By TCF12 Promote Colorectal Cancer Progression via EMT.
Yan S, Yuan M, Yang X, Huang X, Wu D, Wang N, Sun X, Qin Y, Fei Y, Zhao Z, Wang Q. | 07/26/2024 |
| Nuclear Tubulin Enhances CXCR4 Transcription and Promotes Chemotaxis Through TCF12 Transcription Factor in human Hematopoietic Stem Cells. | Nuclear Tubulin Enhances CXCR4 Transcription and Promotes Chemotaxis Through TCF12 Transcription Factor in human Hematopoietic Stem Cells.
Geng N, Yu Z, Zeng X, Xu D, Gao H, Yang M, Huang X. | 11/7/2023 |
| RNA-binding protein DHX9 promotes glioma growth and tumor-associated macrophages infiltration via TCF12. | RNA-binding protein DHX9 promotes glioma growth and tumor-associated macrophages infiltration via TCF12.
Liu L, Zhou X, Cheng S, Ge Y, Chen B, Shi J, Li H, Li S, Li Y, Yuan J, Wu A, Liu X, Huang S, Xu Z, Dong J., Free PMC Article | 03/24/2023 |
| Circular RNA hsa_circ_0002938 (circCRIM1) promotes the progression of esophageal squamous cell carcinoma by upregulating transcription factor 12. | Circular RNA hsa_circ_0002938 (circCRIM1) promotes the progression of esophageal squamous cell carcinoma by upregulating transcription factor 12.
Li XP, Jia YL, Duan YQ, Zhao Y, Yin XL, Zhen SM, Zhang Y, Liu LH. | 03/21/2023 |
| Auricles Anomalies in Patients With a TCF12 Gene Mutation. | Auricles Anomalies in Patients With a TCF12 Gene Mutation.
Lacroix G, Karnoub MA, Vinchon M, Wolber A, Martinot V, Guerreschi P. | 01/28/2023 |
| miR-218-5p inhibits the malignant progression of glioma via targeting TCF12. | miR-218-5p inhibits the malignant progression of glioma via targeting TCF12.
Gu J, Ge X, You A, Li J, Zhang Y, Rao G, Wang J, Zhang K, Liu X, Wu X, Cheng L, Zhu M, Wang D. | 07/30/2022 |
| Evaluation of dental maturity in Muenke syndrome, Saethre-Chotzen syndrome, and TCF12-related craniosynostosis. | Evaluation of dental maturity in Muenke syndrome, Saethre-Chotzen syndrome, and TCF12-related craniosynostosis.
Choi TM, Kramer GJC, Goos JAC, Mathijssen IMJ, Wolvius EB, Ongkosuwito EM., Free PMC Article | 05/28/2022 |
| Long non-coding RNA GLIDR accelerates the tumorigenesis of lung adenocarcinoma by miR-1270/TCF12 axis. | Long non-coding RNA GLIDR accelerates the tumorigenesis of lung adenocarcinoma by miR-1270/TCF12 axis.
Tai G, Fu H, Bai H, Liu H, Li L, Song T., Free PMC Article | 04/16/2022 |
| Craniofacial morphology and growth in Muenke syndrome, Saethre-Chotzen syndrome, and TCF12-related craniosynostosis. | Craniofacial morphology and growth in Muenke syndrome, Saethre-Chotzen syndrome, and TCF12-related craniosynostosis.
Choi TM, Lijten OW, Mathijssen IMJ, Wolvius EB, Ongkosuwito EM., Free PMC Article | 03/12/2022 |
| Circ_0000388 Exerts Oncogenic Function in Cervical Cancer Cells by Regulating miR-337-3p/TCF12 Axis. | Circ_0000388 Exerts Oncogenic Function in Cervical Cancer Cells by Regulating miR-337-3p/TCF12 Axis.
Meng QH, Li Y, Kong C, Gao XM, Jiang XJ. | 10/9/2021 |
| Neurodevelopmental, Cognitive, and Psychosocial Outcomes for Individuals With Pathogenic Variants in the TCF12 Gene and Associated Craniosynostosis. | Neurodevelopmental, Cognitive, and Psychosocial Outcomes for Individuals With Pathogenic Variants in the TCF12 Gene and Associated Craniosynostosis.
Kennedy-Williams P, Care H, Dalton L, Horton J, Kearney A, Rooney N, Hotton M, Pinckston M, Huggons E, Culshaw L, Kilcoyne S, Johnson D, Wilkie AOM, Wall S. | 09/4/2021 |
| TCF12 haploinsufficiency causes autosomal dominant Kallmann syndrome and reveals network-level interactions between causal loci. | TCF12 haploinsufficiency causes autosomal dominant Kallmann syndrome and reveals network-level interactions between causal loci.
Davis EE, Balasubramanian R, Kupchinsky ZA, Keefe DL, Plummer L, Khan K, Meczekalski B, Heath KE, Lopez-Gonzalez V, Ballesta-Martinez MJ, Margabanthu G, Price S, Greening J, Brauner R, Valenzuela I, Cusco I, Fernandez-Alvarez P, Wierman ME, Li T, Lage K, Barroso PS, Chan YM, Crowley WF, Katsanis N., Free PMC Article | 08/21/2021 |
| SNHG1/miR-556-5p/TCF12 feedback loop enhances the tumorigenesis of meningioma through Wnt signaling pathway. | SNHG1/miR-556-5p/TCF12 feedback loop enhances the tumorigenesis of meningioma through Wnt signaling pathway.
Zhang Y, Yu R, Li Q, Li Y, Xuan T, Cao S, Zheng J. | 05/15/2021 |
| Proliferation and migration of hepatocellular carcinoma are accelerated by LINC01287 via the miR-559/TCF12 axis. | Proliferation and migration of hepatocellular carcinoma are accelerated by LINC01287 via the miR-559/TCF12 axis.
Song YB, Yu Z, Fu AQ, Zhou DM. | 04/24/2021 |
| Study demonstrates that TCF12 is a direct target of miR26a, and upregulation of miR26a resulted in TCF12 inhibition in epithelial ovarian cancer (OC) cells. Furthermore, the proliferation, migration and invasion were inhibited and apoptosis was induced by miR26a upregulation in OC cells. These results indicated that miR26a may act as a tumor suppressor in OC, and TCF12 targeting by miR26a. | miR‑26a inhibits ovarian cancer cell proliferation, migration and invasion by targeting TCF12.
Gao S, Bian T, Su M, Liu Y, Zhang Y. | 06/6/2020 |
| The results suggest that TCF12 is a poor prognostic factor of ovarian cancer | TCF12 overexpression as a poor prognostic factor in ovarian cancer.
Gao S, Bian T, Zhang Y, Su M, Liu Y. | 02/29/2020 |
| directly interacts with AML1-ETO, confers new DNA-binding capacity to the AML1-ETO-containing transcription factor complex, and is essential for leukemogenesis | Different roles of E proteins in t(8;21) leukemia: E2-2 compromises the function of AETFC and negatively regulates leukemogenesis.
Liu N, Song J, Xie Y, Wang XL, Rong B, Man N, Zhang MM, Zhang Q, Gao FF, Du MR, Zhang Y, Shen J, Xu CH, Hu CL, Wu JC, Liu P, Zhang YL, Xie YY, Liu P, Huang JY, Huang QH, Lan F, Shen S, Nimer SD, Chen Z, Chen SJ, Roeder RG, Wang L, Sun XJ., Free PMC Article | 03/16/2019 |
| Pathogenic or likely pathogenic variants in non-FGFR genes were identified in 43 individuals, with diagnostic yields of 14% and 15% in retrospective and prospective cohorts, respectively. Variants were identified most frequently in TCF12 (N = 22) and EFNB1 (N = 8), typically in individuals with nonsyndromic coronal craniosynostosis or TWIST1-negative clinically suspected Saethre-Chotzen syndrome. | A craniosynostosis massively parallel sequencing panel study in 309 Australian and New Zealand patients: findings and recommendations.
Lee E, Le T, Zhu Y, Elakis G, Turner A, Lo W, Venselaar H, Verrenkamp CA, Snow N, Mowat D, Kirk EP, Sachdev R, Smith J, Brown NJ, Wallis M, Barnett C, McKenzie F, Freckmann ML, Collins F, Chopra M, Gregersen N, Hayes I, Rajagopalan S, Tan TY, Stark Z, Savarirayan R, Yeung A, Adès L, Gattas M, Gibson K, Gabbett M, Amor DJ, Lattanzi W, Boyd S, Haan E, Gianoutsos M, Cox TC, Buckley MF, Roscioli T. | 02/2/2019 |
| These results identify HEB as a critical regulator of human mesodermal and hematopoietic specification. | Targeted Disruption of TCF12 Reveals HEB as Essential in Human Mesodermal Specification and Hematopoiesis.
Li Y, Brauer PM, Singh J, Xhiku S, Yoganathan K, Zúñiga-Pflücker JC, Anderson MK., Free PMC Article | 05/19/2018 |
| HDAC1 promoted migration and invasion of gallbladder tumor cells by binding with TCF12 to promote epithelial mesenchymal transformation. | HDAC1 promoted migration and invasion binding with TCF12 by promoting EMT progress in gallbladder cancer.
He J, Shen S, Lu W, Zhou Y, Hou Y, Zhang Y, Jiang Y, Liu H, Shao Y., Free PMC Article | 12/30/2017 |
| Study describes the identification of three large inherited intragenic exon deletions in TCF12 using whole-genome sequencing and one large inherited duplication using targeted TCF12 sequencing in patients with craniosynostosis. | Identification of Intragenic Exon Deletions and Duplication of TCF12 by Whole Genome or Targeted Sequencing as a Cause of TCF12-Related Craniosynostosis.
Goos JA, Fenwick AL, Swagemakers SM, McGowan SJ, Knight SJ, Twigg SR, Hoogeboom AJ, van Dooren MF, Magielsen FJ, Wall SA, Mathijssen IM, Wilkie AO, van der Spek PJ, van den Ouweland AM., Free PMC Article | 12/16/2017 |
| Heb expression is regulated by Med19 in breast cancer cells. | Med19 promotes breast cancer cell proliferation by regulating CBFA2T3/HEB expression.
Zhang X, Fan Y, Liu B, Qi X, Guo Z, Li L. | 07/15/2017 |
| enforced expression of transcription factor 12 suppressed cell proliferation, migration, and invasion in vitro and inhibited tumor growth in vivo. In conclusion, transcription factor 12 protein may be a novel molecule which plays a critical role in prostate cancer progression and patients' prognosis, suggesting it might be a promising therapeutic target for prostate cancer therapy | Decreased expression of TCF12 contributes to progression and predicts biochemical recurrence in patients with prostate cancer.
Chen QB, Liang YK, Zhang YQ, Jiang MY, Han ZD, Liang YX, Wan YP, Yin J, He HC, Zhong WD. | 07/15/2017 |
| HEB may be involved in GBM cell proliferation, as HEB silencing reduced proliferation in cells cultured as monolayers or neurospheres. Furthermore, the results suggested a potential role for HEB in the maintenance of GBM stem cells, as HEB silencing affected the differentiation capacity of cells. | HEB silencing induces anti-proliferative effects on U87MG cells cultured as neurospheres and monolayers.
Godoy PR, Montaldi AP, Sakamoto-Hojo ET. | 04/8/2017 |