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    MIR630 microRNA 630 [ Homo sapiens (human) ]

    Gene ID: 693215, updated on 10-Dec-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    CircMAP3K4 Suppresses H2O2-Induced Human Lens Epithelial Cell Injury by miR-630/ERCC6 Axis in Age-Related Cataract.

    CircMAP3K4 Suppresses H2O2-Induced Human Lens Epithelial Cell Injury by miR-630/ERCC6 Axis in Age-Related Cataract.
    Cui F, Sun Z, Zhang X, Liu C.

    04/23/2024
    MiR-630 Promotes Radioresistance by Induction of Anti-Apoptotic Effect via Nrf2-GPX2 Molecular Axis in Head-Neck Cancer.

    MiR-630 Promotes Radioresistance by Induction of Anti-Apoptotic Effect via Nrf2-GPX2 Molecular Axis in Head-Neck Cancer.
    You GR, Cheng AJ, Shen EY, Fan KH, Huang YF, Huang YC, Chang KP, Chang JT., Free PMC Article

    01/3/2024
    CircCERS6 Suppresses the Development of Epithelial Ovarian Cancer Through Mediating miR-630/RASSF8.

    CircCERS6 Suppresses the Development of Epithelial Ovarian Cancer Through Mediating miR-630/RASSF8.
    Li X, Jiang X, Lu J, Lin Y, Jiang L, Li Y, Wan F, Wang C.

    11/5/2022
    HIF-3alpha-Induced miR-630 Expression Promotes Cancer Hallmarks in Cervical Cancer Cells by Forming a Positive Feedback Loop.

    HIF-3α-Induced miR-630 Expression Promotes Cancer Hallmarks in Cervical Cancer Cells by Forming a Positive Feedback Loop.
    Gao Q, Ren Z, Jiao S, Guo J, Miao X, Wang J, Liu J., Free PMC Article

    10/29/2022
    CircPAG1 Inhibits the High Glucose-Induced Lens Epithelial Cell Injury by Sponging miR-630 and Upregulating EPHA2.

    CircPAG1 Inhibits the High Glucose-Induced Lens Epithelial Cell Injury by Sponging miR-630 and Upregulating EPHA2.
    Yang Y, Li Q, Zhang X, Cui G.

    03/5/2022
    Circular RNA MTO1 intercorrelates with microRNA-630, both associate with Enneking stage and/or pathological fracture as well as prognosis in osteosarcoma patients.

    Circular RNA MTO1 intercorrelates with microRNA-630, both associate with Enneking stage and/or pathological fracture as well as prognosis in osteosarcoma patients.
    Shi Z, Wen Y, Zhang S, Cheng X., Free PMC Article

    02/26/2022
    MicroRNA 630 Represses NANOG Expression through Transcriptional and Post-Transcriptional Regulation in Human Embryonal Carcinoma Cells.

    MicroRNA 630 Represses NANOG Expression through Transcriptional and Post-Transcriptional Regulation in Human Embryonal Carcinoma Cells.
    Chu WK, Hung LM, Hou CW, Chen JK., Free PMC Article

    01/29/2022
    Effect of miR-630 expression on esophageal cancer cell invasion and migration.

    Effect of miR-630 expression on esophageal cancer cell invasion and migration.
    Liu X, Wu W, Zhang S, Tan W, Qiu Y, Liao K, Yang K., Free PMC Article

    12/11/2021
    Circular RNA CircMTO1 suppressed proliferation and metastasis of osteosarcoma through miR-630/KLF6 axis.

    Circular RNA CircMTO1 suppressed proliferation and metastasis of osteosarcoma through miR-630/KLF6 axis.
    Liu DY, Li Z, Zhang K, Jiao N, Lu DG, Zhou DW, Meng YB, Sun L.

    07/3/2021
    High-throughput microRNA profile in adult and pediatric primary glioblastomas: the role of miR-10b-5p and miR-630 in the tumor aggressiveness.

    High-throughput microRNA profile in adult and pediatric primary glioblastomas: the role of miR-10b-5p and miR-630 in the tumor aggressiveness.
    Junior LGD, Baroni M, Lira RCP, Teixeira S, Fedatto PF, Silveira VS, Suazo VK, Veronez LC, Panepucci RA, Antônio DSM, Yunes JA, Brandalise SR, Dos Santos Aguiar S, Neder L, de Oliveira RS, Machado HR, Carlotti CG Jr, Tone LG, Valera ET, Scrideli CA.

    05/22/2021
    microRNA-630 Regulates Underglycosylated IgA1 Production in the Tonsils by Targeting TLR4 in IgA Nephropathy.

    microRNA-630 Regulates Underglycosylated IgA1 Production in the Tonsils by Targeting TLR4 in IgA Nephropathy.
    Liu C, Ye MY, Yan WZ, Peng XF, He LY, Peng YM., Free PMC Article

    05/8/2021
    Upregulation of miR-630 Induced by Oxidative Damage Resists Cell Migration Through Targeting ALCAM in Human Lens Epithelium Cells.

    Upregulation of miR-630 Induced by Oxidative Damage Resists Cell Migration Through Targeting ALCAM in Human Lens Epithelium Cells.
    Mei L, Yan H, Wang S, Guo C, Zheng X, Yan B, Zhao J, Yang A.

    12/26/2020
    MiR-630 inhibits papillary thyroid carcinoma cell growth, metastasis, and epithelial-mesenchymal transition by suppressing JAK2/STAT3 signaling pathway.

    MiR-630 inhibits papillary thyroid carcinoma cell growth, metastasis, and epithelial-mesenchymal transition by suppressing JAK2/STAT3 signaling pathway.
    Pan XM, He XY, Yang YL, Jia WJ, Yang ZQ, Yan D, Ma JX.

    08/13/2020
    Data indicate that circMTDH.4/miR-630/astrocyte elevated gene-1 (AEG-1) axis is responsible for chemoresistance and radioresistance in non-small-cell lung cancer (NSCLC) cells.

    circMTDH.4/miR-630/AEG-1 axis participates in the regulation of proliferation, migration, invasion, chemoresistance, and radioresistance of NSCLC.
    Li YH, Xu CL, He CJ, Pu HH, Liu JL, Wang Y.

    04/25/2020
    The present study demonstrated that three miRNAs (miR-548q, miR-630 and miR940) might be novel and useful biomarkers for nasopharyngeal carcinoma (NPC) detection. A two-miRNA signature (miR-548q and miR940) may be considered as a better biomarker for NPC detection with relatively high sensitivity and specificity.

    Plasma microRNA expression signature involving miR-548q, miR-630 and miR-940 as biomarkers for nasopharyngeal carcinoma detection.
    Zhuo X, Zhou W, Li D, Chang A, Wang Y, Wu Y, Zhou Q.

    04/6/2019
    MiR-630 may be a potential biomarker for the prediction of tyrosine kinase inhibitors therapeutic response and outcome in patients with lung adenocarcinoma.

    A low microRNA-630 expression confers resistance to tyrosine kinase inhibitors in EGFR-mutated lung adenocarcinomas via miR-630/YAP1/ERK feedback loop.
    Wu DW, Wang YC, Wang L, Chen CY, Lee H., Free PMC Article

    01/19/2019
    these findings provide further evidence on the tumor-suppression function of miR-630 in breast cancer, and clarify BMI1 as a novel functional target gene of miR-630.

    MicroRNA-630 inhibits breast cancer progression by directly targeting BMI1.
    Gong XF, Yu AL, Tang J, Wang CL, He JR, Chen GQ, Zhao Q, He M, Zhou CX.

    10/6/2018
    The volume of tumors in miR-630 mimics treatment increased rapidly compared with that in control group and overexpression promotes SKOV3 cell proliferation and migration.

    MiR-630 promotes epithelial ovarian cancer proliferation and invasion via targeting KLF6.
    Zhang S, Zhang JY, Lu LJ, Wang CH, Wang LH.

    08/11/2018
    Inhibition of miR-630 decreased cell proliferation and enhanced the sensitivity of SKOV3-TR and SKOV3 cells to paclitaxel.

    MicroRNA-630 inhibitor sensitizes chemoresistant ovarian cancer to chemotherapy by enhancing apoptosis.
    Eoh KJ, Lee SH, Kim HJ, Lee JY, Kim S, Kim SW, Kim YT, Nam EJ.

    04/7/2018
    These results suggest that circRNA_100269 and miR-630 comprise a novel pathway that regulates proliferation of GC cells.

    CircRNA_100269 is downregulated in gastric cancer and suppresses tumor cell growth by targeting miR-630.
    Zhang Y, Liu H, Li W, Yu J, Li J, Shen Z, Ye G, Qi X, Li G., Free PMC Article

    03/31/2018
    these findings demonstrate, in hepatocellular carcinoma cells, miR-630 exerts its tumor-suppressor functions through the TGF-beta-miR-630-Slug axis

    MicroRNA-630 suppresses tumor metastasis through the TGF-β- miR-630-Slug signaling pathway and correlates inversely with poor prognosis in hepatocellular carcinoma.
    Chen WX, Zhang ZG, Ding ZY, Liang HF, Song J, Tan XL, Wu JJ, Li GZ, Zeng Z, Zhang BX, Chen XP., Free PMC Article

    12/16/2017
    a clear mechanistic link between hypoxia and tumor progression via upregulation of miR-630 and downregulation of Dicer.

    Hypoxia-upregulated microRNA-630 targets Dicer, leading to increased tumor progression.
    Rupaimoole R, Ivan C, Yang D, Gharpure KM, Wu SY, Pecot CV, Previs RA, Nagaraja AS, Armaiz-Pena GN, McGuire M, Pradeep S, Mangala LS, Rodriguez-Aguayo C, Huang L, Bar-Eli M, Zhang W, Lopez-Berestein G, Calin GA, Sood AK., Free PMC Article

    09/2/2017
    putative key mediator of vascular function and cardiovascular disease risk in children with underlying OSA and/or obesity

    Circulating Plasma Extracellular Microvesicle MicroRNA Cargo and Endothelial Dysfunction in Children with Obstructive Sleep Apnea.
    Khalyfa A, Kheirandish-Gozal L, Khalyfa AA, Philby MF, Alonso-Álvarez ML, Mohammadi M, Bhattacharjee R, Terán-Santos J, Huang L, Andrade J, Gozal D., Free PMC Article

    07/8/2017
    H19 inhibited E-cadherin expression and promoted cell invasion of NPC cells via the miR-630/EZH2 pathway

    Long noncoding RNA H19 regulates EZH2 expression by interacting with miR-630 and promotes cell invasion in nasopharyngeal carcinoma.
    Li X, Lin Y, Yang X, Wu X, He X.

    06/24/2017
    results suggest that miR-630 might be a tumor suppressor in GC cells. MiR-630 suppresses EMT by regulating FoxM1 in Gastric Cancer cells, supposedly via inactivation of the Ras/PI3K/AKT pathway

    MicroRNA-630 Suppresses Epithelial-to-Mesenchymal Transition by Regulating FoxM1 in Gastric Cancer Cells.
    Feng J, Wang X, Zhu W, Chen S, Feng C.

    06/24/2017
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