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    MIR598 microRNA 598 [ Homo sapiens (human) ]

    Gene ID: 693183, updated on 4-Jan-2025

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Circ_0007580 knockdown strengthens the radiosensitivity of non-small cell lung cancer via the miR-598-dependent regulation of THBS2.

    Circ_0007580 knockdown strengthens the radiosensitivity of non-small cell lung cancer via the miR-598-dependent regulation of THBS2.
    Yang Z, Wu H, Zhang K, Rao S, Qi S, Liu M, Chen Y, Wang Y., Free PMC Article

    03/26/2022
    circCELSR1 facilitates ovarian cancer proliferation and metastasis by sponging miR-598 to activate BRD4 signals.

    circCELSR1 facilitates ovarian cancer proliferation and metastasis by sponging miR-598 to activate BRD4 signals.
    Zeng XY, Yuan J, Wang C, Zeng D, Yong JH, Jiang XY, Lan H, Xiao SS., Free PMC Article

    09/11/2021
    CircB3GNTL1 and miR-598 regulation effects on proliferation, apoptosis, and glutaminolysis in gastric cancer cells.

    CircB3GNTL1 and miR-598 regulation effects on proliferation, apoptosis, and glutaminolysis in gastric cancer cells.
    Ye B, Yu S, Wang J, Ren Y.

    08/7/2021
    MicroRNA-598 acts as an inhibitor in retinoblastoma through targeting E2F1 and regulating AKT pathway.

    MicroRNA-598 acts as an inhibitor in retinoblastoma through targeting E2F1 and regulating AKT pathway.
    Liu F, Zhang Q, Liang Y.

    06/19/2021
    LINC01296/miR-598/Twist1 constitutes a positive feedback loop to promote the tumorigenesis of non-small cell lung cancer.

    Positive feedback loop of lncRNA LINC01296/miR-598/Twist1 promotes non-small cell lung cancer tumorigenesis.
    Xu L, Wei B, Hui H, Sun Y, Liu Y, Yu X, Dai J.

    03/21/2020
    High miR598 expression is associated with ulcerative colitis as compared to Crohn's colitis.

    Plasma microRNA Profile Differentiates Crohn's Colitis From Ulcerative Colitis.
    Netz U, Carter J, Eichenberger MR, Feagins K, Galbraith NJ, Dryden GW, Pan J, Rai SN, Galandiuk S., Free PMC Article

    02/23/2019
    In this study, authors found that miRNA-598 (miR-598) expression was significantly downregulated in GBM tissues and cell lines. Restoring miR-598 expression inhibited cell proliferation and invasion in GBM.

    MicroRNA-598 Inhibits Cell Proliferation and Invasion of Glioblastoma by Directly Targeting Metastasis Associated in Colon Cancer-1 (MACC1).
    Wang N, Zhang Y, Liang H., Free PMC Article

    12/22/2018
    miR598 contributed to cell proliferation and cell cycle progression in colorectal carcinoma by targeting INPP5E.

    Upregulation of miR‑598 promotes cell proliferation and cell cycle progression in human colorectal carcinoma by suppressing INPP5E expression.
    Li KP, Fang YP, Liao JQ, Duan JD, Feng LG, Luo XZ, Liang ZJ., Free PMC Article

    08/25/2018
    These findings for the first time revealed that miR-598, as a tumor suppressor, negatively regulate DERL1 and Epithelial-Mesenchymal Transition to suppress the invasion and migration in Non-Small Cell Lung Cancer (NSCLC), thereby putatively serving as a novel therapeutic target for NSCLC clinical treatment.

    MiR-598 Suppresses Invasion and Migration by Negative Regulation of Derlin-1 and Epithelial-Mesenchymal Transition in Non-Small Cell Lung Cancer.
    Yang F, Wei K, Qin Z, Liu W, Shao C, Wang C, Ma L, Xie M, Shu Y, Shen H.

    08/25/2018
    findings enrich the knowledge of miR-598 in osteosarcoma progression.

    MiR-598: A tumor suppressor with biomarker significance in osteosarcoma.
    Liu K, Sun X, Zhang Y, Liu L, Yuan Q.

    09/30/2017
    High miR598 expression is associated with Invasive Pituitary Adenomas.

    Novel Biomarkers for Non-functioning Invasive Pituitary Adenomas were Identified by Using Analysis of microRNAs Expression Profile.
    Wu S, Gu Y, Huang Y, Wong TC, Ding H, Liu T, Zhang Y, Zhang X.

    06/24/2017
    Low miR598 expression is associated with metastasis in colorectal cancer.

    miR-598 inhibits metastasis in colorectal cancer by suppressing JAG1/Notch2 pathway stimulating EMT.
    Chen J, Zhang H, Chen Y, Qiao G, Jiang W, Ni P, Liu X, Ma L.

    06/3/2017
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