| Exosome-Delivered circSTAU2 Inhibits the Progression of Gastric Cancer by Targeting the miR-589/CAPZA1 Axis. | Exosome-Delivered circSTAU2 Inhibits the Progression of Gastric Cancer by Targeting the miR-589/CAPZA1 Axis.
Zhang C, Wei G, Zhu X, Chen X, Ma X, Hu P, Liu W, Yang W, Ruan T, Zhang W, Wu C, Tao K., Free PMC Article | 01/21/2023 |
| miR-589-5p Inhibits Cell Proliferation by Targeting Histone Deacetylase 3 in Triple Negative Breast Cancer. | miR-589-5p Inhibits Cell Proliferation by Targeting Histone Deacetylase 3 in Triple Negative Breast Cancer.
Rahbari R, Rahimi K, Rasmi Y, Khadem-Ansari MH, Abdi M. | 08/13/2022 |
| Identification and Characterization of the Roles of circCASP9 in Gastric Cancer Based on a circRNA-miRNA-mRNA Regulatory Network. | Identification and Characterization of the Roles of circCASP9 in Gastric Cancer Based on a circRNA-miRNA-mRNA Regulatory Network.
Qin C, Zhang H, Guo X, Cheng A, Liu H, Wang Z., Free PMC Article | 04/9/2022 |
| Downregulation of circ-UBAP2 ameliorates oxidative stress and dysfunctions of human retinal microvascular endothelial cells (hRMECs) via miR-589-5p/EGR1 axis. | Downregulation of circ-UBAP2 ameliorates oxidative stress and dysfunctions of human retinal microvascular endothelial cells (hRMECs) via miR-589-5p/EGR1 axis.
Jiewei Y, Jingjing Z, Jingjing X, Guilan Z., Free PMC Article | 02/26/2022 |
| Circ_0003423 Alleviates ox-LDL-Induced Human Brain Microvascular Endothelial Cell Injury via the miR-589-5p/TET2 Network. | Circ_0003423 Alleviates ox-LDL-Induced Human Brain Microvascular Endothelial Cell Injury via the miR-589-5p/TET2 Network.
Yu H, Pan Y, Dai M, Xu H, Li J. | 02/5/2022 |
| Long non-coding RNA CCDC183-AS1 acts AS a miR-589-5p sponge to promote the progression of hepatocellular carcinoma through regulating SKP1 expression. | Long non-coding RNA CCDC183-AS1 acts AS a miR-589-5p sponge to promote the progression of hepatocellular carcinoma through regulating SKP1 expression.
Zhu H, Zhang H, Pei Y, Liao Z, Liu F, Su C, Liu Y, Dong R, Song J, Zhang X, Fan Y, Liang H, Zhang B, Chen X., Free PMC Article | 10/16/2021 |
| miR5893p sponged by the lncRNA TINCR inhibits the proliferation, migration and invasion and promotes the apoptosis of breast cancer cells by suppressing the Akt pathway via IGF1R. | miR‑589‑3p sponged by the lncRNA TINCR inhibits the proliferation, migration and invasion and promotes the apoptosis of breast cancer cells by suppressing the Akt pathway via IGF1R.
Guo F, Zhu X, Zhao Q, Huang Q., Free PMC Article | 06/5/2021 |
| Cyclic RNA hsa_circ_0091017 inhibits proliferation, migration and invasiveness of bladder cancer cells by binding to microRNA-589-5p. | Cyclic RNA hsa_circ_0091017 inhibits proliferation, migration and invasiveness of bladder cancer cells by binding to microRNA-589-5p.
Zhang L, Xia HB, Zhao CY, Shi L, Ren XL. | 11/21/2020 |
| results show that dysregulation of circPRKCI-miR-545/589-E2F7 axis mediated H2O2-induced neuronal cell injury; targeting this novel cascade could be a fine strategy to protect neurons from oxidative stress | CircPRKCI-miR-545/589-E2F7 axis dysregulation mediates hydrogen peroxide-induced neuronal cell injury.
Cheng Q, Cao X, Xue L, Xia L, Xu Y. | 07/11/2020 |
| Low miR589 expression is associated with Cell Proliferation, Cell Migration and Invasion in Endometrial Carcinoma. | Targeting Thyroid Receptor Interacting Protein 6 by MicroRNA-589-5p Inhibits Cell Proliferation, Migration, and Invasion in Endometrial Carcinoma.
Wang Y, Dong L, Liu Y. | 02/15/2020 |
| miR5895p may act as a tumor suppressor in prostate cancer by targeting CCL5 | miR‑589‑5p is downregulated in prostate cancer and regulates tumor cell viability and metastasis by targeting CCL‑5.
Ji L, Jiang X, Mao F, Tang Z, Zhong B. | 12/14/2019 |
| The edited version of miR-589-3p inhibits glioblastoma cell proliferation, migration and invasion, while the unedited version boosts cell proliferation and motility/invasion. | ADAR2/miR-589-3p axis controls glioblastoma cell migration/invasion.
Cesarini V, Silvestris DA, Tassinari V, Tomaselli S, Alon S, Eisenberg E, Locatelli F, Gallo A., Free PMC Article | 07/20/2019 |
| miR-589-5p facilitated the growth of liver cancer cells by targeting MIG-6 and could be a prognosis biomarker for hepatocellular carcinoma | MiR-589-5p is a potential prognostic marker of hepatocellular carcinoma and regulates tumor cell growth by targeting MIG-6.
Xu M, Wang Y, He HT, Yang Q. | 07/6/2019 |
| Data report that miR-589-5p is elevated in hepatocellular carcinoma (HCC) tissues, which is caused by recurrent gains. Its overexpression correlates with poor overall and relapse-free survival in HCC patients. These findings demonstrate miR-589-5 promotes the cancer stem cell characteristics and chemoresistance via multiple negative regulators of STAT3 signaling pathway leading to its constitutive activation. | Maintenance of stemness by miR-589-5p in hepatocellular carcinoma cells promotes chemoresistance via STAT3 signaling.
Long J, Jiang C, Liu B, Dai Q, Hua R, Chen C, Zhang B, Li H. | 06/22/2019 |
| These findings demonstrate a novel mechanism for deregulation of HDAC5 in non-small cell lung cancer (NSCLC)and suggest that miR5895p/HDAC5 pathway may represent a new prognostic biomarker and therapeutic target against NSCLC. | Hypermethylation of miRNA-589 promoter leads to upregulation of HDAC5 which promotes malignancy in non-small cell lung cancer.
Liu C, Lv D, Li M, Zhang X, Sun G, Bai Y, Chang D. | 03/3/2018 |
| Results show that miR-589 is down-regulated in CD90+ cancer stem cells in hepatocellular carcinoma (HCC) cells. MiR-589 down-regulates the stemness characteristics of CD90+ cancer stem cells in part by silencing MAP3K8. | miR-589-5p inhibits MAP3K8 and suppresses CD90(+) cancer stem cells in hepatocellular carcinoma.
Zhang X, Jiang P, Shuai L, Chen K, Li Z, Zhang Y, Jiang Y, Li X., Free PMC Article | 12/16/2017 |
| miR-21 and miR-589 showed consistently significant relation with peritoneal transport | Peritoneal dialysis effluent miR-21 and miR-589 levels correlate with longitudinal change in peritoneal transport characteristics.
Szeto CC, Chow KM, Kwan BC, Cheng PM, Luk CC, Ng JK, Law MC, Leung CB, Li PK. | 02/18/2017 |
| microRNA222 and microRNA589 were pivotal for the development of intervertebral disc degeneration | Microarray based analysis of gene regulation by microRNA in intervertebral disc degeneration.
Hu P, Feng B, Wang G, Ning B, Jia T., Free PMC Article | 08/6/2016 |
| miRNA589 mediates TGFbeta1 induced epithelial-mesenchymal transition in human peritoneal mesothelial cells. | miRNA589 regulates epithelial-mesenchymal transition in human peritoneal mesothelial cells.
Zhang K, Zhang H, Zhou X, Tang WB, Xiao L, Liu YH, Liu H, Peng YM, Sun L, Liu FY., Free PMC Article | 04/13/2013 |