STAT4 and STAT6, their role in cellular and humoral immunity and in diverse human diseases.
Tolomeo M, Cascio A.

Signal Transducer and Activator of Transcription 4-Induced Up-Regulated LINC01278 Enhances Proliferation and Invasion of Non-Small Cell Lung Cancer Cells via the MicroRNA-877-5p/Activating Transcription Factor 4 Axis.
Yang L, Xiao Y, Deng S, Yan D, Li Z, Wang Y, Lei C.,

Investigating the Link between STAT4 Genetic Variants, STAT4 Protein Concentrations, and Laryngeal Squamous Cell Carcinoma: A Comprehensive Analysis of Clinical Manifestations.
Pileckaite E, Vilkeviciute A, Kriauciuniene L, Liutkevicius V, Liutkeviciene R., Free PMC Article

Association between STAT4 gene polymorphism and susceptibility to pulmonary tuberculosis in the Moldavian population.
Varzari A, Tudor E, Corloteanu A, Axentii E, Vladei I, Deyneko IV.

Association between STAT4 gene polymorphism and type 2 diabetes risk in Chinese Han population.
Cui J, Tong R, Xu J, Tian Y, Pan J, Wang N, Chen H, Peng Y, Fei S, Ling W, Guo C, Yao J, Cui W., Free PMC Article

The Role of JAK-STAT-SOCS1 Axis in Tumorigenesis, Malignant Progression and Lymphatic Metastasis of Penile Cancer.
Xu DM, Chen LX, Zhuang XY, Han H, Mo M., Free PMC Article

STAT4 targets KISS1 to inhibit the oxidative damage, inflammation and neuronal apoptosis in experimental PD models by inactivating the MAPK pathway.
Zhang X, Wang Y, Lv J.

Single-cell deconvolution algorithms analysis unveils autocrine IL11-mediated resistance to docetaxel in prostate cancer via activation of the JAK1/STAT4 pathway.
Cheng B, Li L, Luo T, Wang Q, Luo Y, Bai S, Li K, Lai Y, Huang H., Free PMC Article

STAT4 Gene Variant rs7574865 Is Associated with Rheumatoid Arthritis Activity and Anti-CCP Levels in the Western but Not in the Southern Population of Mexico.
Bravo-Villagra KM, Muñoz-Valle JF, Baños-Hernández CJ, Cerpa-Cruz S, Navarro-Zarza JE, Parra-Rojas I, Aguilar-Velázquez JA, García-Arellano S, López-Quintero A., Free PMC Article

TOX, TWIST1, STAT4, and SATB1 protein expressions in early-stage mycosis fungoides.
Örnek S, Ozekinci S, Ipin T, Kocaturk E.

Divergent roles for STAT4 in shaping differentiation of cytotoxic ILC1 and NK cells during gut inflammation.
Scarno G, Mazej J, Laffranchi M, Di Censo C, Mattiola I, Candelotti AM, Pietropaolo G, Stabile H, Fionda C, Peruzzi G, Brooks SR, Tsai WL, Mikami Y, Bernardini G, Gismondi A, Sozzani S, Di Santo JP, Vosshenrich CAJ, Diefenbach A, Gadina M, Santoni A, Sciumè G., Free PMC Article

STAT4, a potential predictor of prognosis, promotes CD8 T‑cell infiltration in ovarian serous carcinoma by inducing CCL5 secretion.
Wang W, Liu S, Lu F, Yang B, Zhuang X, Yin J, Chen G, Sun C., Free PMC Article

Down-Regulation-Resistant STAT4 Risk Haplotype Contributes to Lupus Nephritis Through CD4+ T Cell Interferon-γ Production.
Madera-Salcedo IK, Ramírez-Sánchez AL, Rodríguez-Rodríguez N, García-Quintero R, Rubio RM, Morales-Montes de Oca G, Dávalos E, Cuervo R, Furuzawa-Carballeda J, Alcocer-Varela J, Gómez-Martín D, González-Yáñez M, de la Cruz A, Albarrán-Godínez A, Suárez-Rojas G, Romero-Díaz J, Uribe-Uribe NO, Alarcón-Riquelme M, Furlan-Magaril M, Mejía-Vilet JM, Crispín JC, Rosetti F.

Defective binding of ETS1 and STAT4 due to a mutation in the promoter region of THPO as a novel mechanism of congenital amegakaryocytic thrombocytopenia.
Capaci V, Adam E, Bar-Joseph I, Faleschini M, Pecci A, Savoia A., Free PMC Article

Association of the STAT4 Gene rs7574865 Polymorphism with IFN-γ Levels in Patients with Systemic Lupus Erythematosus.
Esparza Guerrero Y, Vazquez Villegas ML, Nava Valdivia CA, Ponce Guarneros JM, Perez Guerrero EE, Gomez Ramirez EE, Ramirez Villafaña M, Contreras Haro B, Martinez Hernandez A, Cardona Muñoz EG, Nuño Arana I, Gallardo Moya SG, Celis A, Gonzalez Lopez L, Gamez Nava JI, Saldaña Cruz AM., Free PMC Article

The effects of the interactions of STAT4 rs7574865 with HBV mutations on the risk of hepatocellular carcinoma.
Yang C, Chen H, Zhou B, Yin J, Cao G, Hou J, Jiang D.

T Cells With Activated STAT4 Drive the High-Risk Rejection State to Renal Allograft Failure After Kidney Transplantation.
Chen Y, Zhang B, Liu T, Chen X, Wang Y, Zhang H., Free PMC Article

STAT4 genetic polymorphism significantly affected HBeAg seroconversion in HBeAg-positive chronic hepatitis B patients receiving Peginterferon-α therapy: A prospective cohort study in China.
Qi X, Li F, Zhang Y, Zhu H, Yang F, Li X, Jiang X, Chen L, Huang Y, Zhang J.

STAT4 and COL1A2 are potential diagnostic biomarkers and therapeutic targets for heart failure comorbided with depression.
Huang K, Zhang X, Duan J, Wang R, Wu Z, Yang C, Yang L.

Occludin facilitates tumour angiogenesis in bladder cancer by regulating IL8/STAT3 through STAT4.
Yang F, Liu XQ, He JZ, Xian SP, Yang PF, Mai ZY, Li M, Liu Y, Zhang XD., Free PMC Article

Stat4 rs7574865 polymorphism promotes the occurrence and progression of hepatocellular carcinoma via the Stat4/CYP2E1/FGL2 pathway.
Wang C, Gao N, Yang L, Guo Y, Fang Y, Wang T, Xu C, Li GF, Zhou J, Zhang Y, Wen Q, Qiao H., Free PMC Article

Regional heritability mapping identifies several novel loci (STAT4, ULK4, and KCNH5) for primary biliary cholangitis in the Japanese population.
Gervais O, Ueno K, Kawai Y, Hitomi Y, Aiba Y, Ueta M, Nakamura M, Tokunaga K, Nagasaki M., Free PMC Article

A new discovery of STAT4 single nucleotide polymorphisms associated with hepatocellular carcinoma risk in Chinese Han population: a case-control study.
Chao X, Wu J, Zhang W, Feng X, Zhao L, Huang F, Jiang C., Free PMC Article

Genetic variants in STAT4 and their interactions with environmental factors for the incidence of hepatocellular carcinoma.
Zhong X, Luo M, Wu Y, Zhou X, Yu X, Liu L, Chen S.

Association of the STAT4, CDKN1A, and IRF5 variants with risk of lupus nephritis and renal biopsy classification in patients in Vietnam.
Nghiem TD, Do GT, Luong LH, Nguyen QL, Dang HV, Viet AN, Nguyen TT, Tran VK, Ta TV, Tran TH., Free PMC Article