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    Piezo2 piezo-type mechanosensitive ion channel component 2 [ Mus musculus (house mouse) ]

    Gene ID: 667742, updated on 27-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Piezo2 voltage-block regulates mechanical pain sensitivity.

    Piezo2 voltage-block regulates mechanical pain sensitivity.
    Sánchez-Carranza O, Chakrabarti S, Kühnemund J, Schwaller F, Bégay V, García-Contreras JA, Wang L, Lewin GR., Free PMC Article

    10/16/2024
    Piezo2 Contributes to Traumatic Brain Injury by Activating the RhoA/ROCK1 Pathways.

    Piezo2 Contributes to Traumatic Brain Injury by Activating the RhoA/ROCK1 Pathways.
    Xiao Y, Zhang Y, Yuan W, Wang C, Ge Y, Huang T, Gao J., Free PMC Article

    09/27/2024
    Phosphatidic acid is an endogenous negative regulator of PIEZO2 channels and mechanical sensitivity.

    Phosphatidic acid is an endogenous negative regulator of PIEZO2 channels and mechanical sensitivity.
    Gabrielle M, Yudin Y, Wang Y, Su X, Rohacs T., Free PMC Article

    09/25/2024
    Plp1-expresssing perineuronal DRG cells facilitate colonic and somatic chronic mechanical pain involving Piezo2 upregulation in DRG neurons.

    Plp1-expresssing perineuronal DRG cells facilitate colonic and somatic chronic mechanical pain involving Piezo2 upregulation in DRG neurons.
    Tiwari N, Smith C, Sharma D, Shen S, Mehta P, Qiao LY., Free PMC Article

    09/25/2024
    Piezo1 and Piezo2 collectively regulate jawbone development.

    Piezo1 and Piezo2 collectively regulate jawbone development.
    Nie X, Abbasi Y, Chung MK.,

    06/27/2024
    Immunolocalization of the mechanogated ion channels PIEZO1 and PIEZO2 in human and mouse dental pulp and periodontal ligament.

    Immunolocalization of the mechanogated ion channels PIEZO1 and PIEZO2 in human and mouse dental pulp and periodontal ligament.
    Gaite JJ, Solé-Magdalena A, García-Mesa Y, Cuendias P, Martin-Cruces J, García-Suárez O, Cobo T, Vega JA, Martín-Biedma B.

    04/16/2024
    Caldendrin Is a Repressor of PIEZO2 Channels and Touch Sensation in Mice.

    Caldendrin Is a Repressor of PIEZO2 Channels and Touch Sensation in Mice.
    Lopez JA, Romero LO, Kaung WL, Maddox JW, Vásquez V, Lee A., Free PMC Article

    03/11/2024
    Differential expression of PIEZO1 and PIEZO2 mechanosensitive channels in ocular tissues implicates diverse functional roles.

    Differential expression of PIEZO1 and PIEZO2 mechanosensitive channels in ocular tissues implicates diverse functional roles.
    Zhu Y, Garcia-Sanchez J, Dalal R, Sun Y, Kapiloff MS, Goldberg JL, Liu WW., Free PMC Article

    11/16/2023
    PIEZO2 and perineal mechanosensation are essential for sexual function.

    PIEZO2 and perineal mechanosensation are essential for sexual function.
    Lam RM, von Buchholtz LJ, Falgairolle M, Osborne J, Frangos E, Servin-Vences MR, Nagel M, Nguyen MQ, Jayabalan M, Saade D, Patapoutian A, Bönnemann CG, Ryba NJP, Chesler AT., Free PMC Article

    08/28/2023
    Piezo2 expressing nociceptors mediate mechanical sensitization in experimental osteoarthritis.

    Piezo2 expressing nociceptors mediate mechanical sensitization in experimental osteoarthritis.
    Obeidat AM, Wood MJ, Adamczyk NS, Ishihara S, Li J, Wang L, Ren D, Bennett DA, Miller RJ, Malfait AM, Miller RE., Free PMC Article

    08/25/2023
    PIEZO2 promotes cell proliferation and metastasis in colon carcinoma through the SLIT2/ROBO1/VEGFC pathway.

    PIEZO2 promotes cell proliferation and metastasis in colon carcinoma through the SLIT2/ROBO1/VEGFC pathway.
    Shang H, Xu A, Yan H, Xu D, Zhang J, Fang X.

    07/27/2023
    Piezo2 regulates colonic mechanical sensitivity in a sex specific manner in mice.

    Piezo2 regulates colonic mechanical sensitivity in a sex specific manner in mice.
    Madar J, Tiwari N, Smith C, Sharma D, Shen S, Elmahdi A, Qiao LY., Free PMC Article

    04/19/2023
    Piezo2 channels expressed by colon-innervating TRPV1-lineage neurons mediate visceral mechanical hypersensitivity.

    Piezo2 channels expressed by colon-innervating TRPV1-lineage neurons mediate visceral mechanical hypersensitivity.
    Xie Z, Feng J, Hibberd TJ, Chen BN, Zhao Y, Zang K, Hu X, Yang X, Chen L, Brookes SJ, Spencer NJ, Hu H., Free PMC Article

    03/14/2023
    Linoleic acid improves PIEZO2 dysfunction in a mouse model of Angelman Syndrome.

    Linoleic acid improves PIEZO2 dysfunction in a mouse model of Angelman Syndrome.
    Romero LO, Caires R, Kaitlyn Victor A, Ramirez J, Sierra-Valdez FJ, Walsh P, Truong V, Lee J, Mayor U, Reiter LT, Vásquez V, Cordero-Morales JF., Free PMC Article

    03/7/2023
    Excessive mechanotransduction in sensory neurons causes joint contractures.

    Excessive mechanotransduction in sensory neurons causes joint contractures.
    Ma S, Dubin AE, Romero LO, Loud M, Salazar A, Chu S, Klier N, Masri S, Zhang Y, Wang Y, Chesler AT, Wilkinson KA, Vásquez V, Marshall KL, Patapoutian A., Free PMC Article

    02/11/2023
    Loss of lung microvascular endothelial Piezo2 expression impairs NO synthesis, induces EndMT, and is associated with pulmonary hypertension.

    Loss of lung microvascular endothelial Piezo2 expression impairs NO synthesis, induces EndMT, and is associated with pulmonary hypertension.
    Tian S, Cai Z, Sen P, van Uden D, van de Kamp E, Thuillet R, Tu L, Guignabert C, Boomars K, Van der Heiden K, Brandt MM, Merkus D.

    01/28/2023
    Midpalatal Suture: Single-Cell RNA-Seq Reveals Intramembrane Ossification and Piezo2 Chondrogenic Mesenchymal Cell Involvement.

    Midpalatal Suture: Single-Cell RNA-Seq Reveals Intramembrane Ossification and Piezo2 Chondrogenic Mesenchymal Cell Involvement.
    Gao L, Xu T, Zhang L, Li Y, Yan T, Yu G, Chen F., Free PMC Article

    12/3/2022
    Electroacupuncture Attenuates Post-Inflammatory IBS-Associated Visceral and Somatic Hypersensitivity and Correlates With the Regulatory Mechanism of Epac1-Piezo2 Axis.

    Electroacupuncture Attenuates Post-Inflammatory IBS-Associated Visceral and Somatic Hypersensitivity and Correlates With the Regulatory Mechanism of Epac1-Piezo2 Axis.
    Guo J, Chen L, Wang YH, Song YF, Zhao ZH, Zhao TT, Lin ZY, Gu DM, Liu YQ, Peng YJ, Pei LX, Sun JH., Free PMC Article

    07/30/2022
    PIEZO2 ion channels in proprioception.

    PIEZO2 ion channels in proprioception.
    Nagel M, Chesler AT.

    07/30/2022
    TMEM120A/TACAN inhibits mechanically activated PIEZO2 channels.

    TMEM120A/TACAN inhibits mechanically activated PIEZO2 channels.
    Del Rosario JS, Gabrielle M, Yudin Y, Rohacs T., Free PMC Article

    07/23/2022
    Peroxisome Metabolism Contributes to PIEZO2-Mediated Mechanical Allodynia.

    Peroxisome Metabolism Contributes to PIEZO2-Mediated Mechanical Allodynia.
    Gong Y, Laheji F, Berenson A, Qian A, Park SO, Kok R, Selig M, Hahn R, Sadjadi R, Kemp S, Eichler F., Free PMC Article

    06/18/2022
    Piezo2 is not an indispensable mechanosensor in murine cardiomyocytes.

    Piezo2 is not an indispensable mechanosensor in murine cardiomyocytes.
    Kloth B, Mearini G, Weinberger F, Stenzig J, Geertz B, Starbatty J, Lindner D, Schumacher U, Reichenspurner H, Eschenhagen T, Hirt MN., Free PMC Article

    05/28/2022
    Piezo2 expression and its alteration by mechanical forces in mouse mesangial cells and renin-producing cells.

    Piezo2 expression and its alteration by mechanical forces in mouse mesangial cells and renin-producing cells.
    Mochida Y, Ochiai K, Nagase T, Nonomura K, Akimoto Y, Fukuhara H, Sakai T, Matsumura G, Yamaguchi Y, Nagase M., Free PMC Article

    05/7/2022
    Functional roles for PIEZO1 and PIEZO2 in urothelial mechanotransduction and lower urinary tract interoception.

    Functional roles for PIEZO1 and PIEZO2 in urothelial mechanotransduction and lower urinary tract interoception.
    Dalghi MG, Ruiz WG, Clayton DR, Montalbetti N, Daugherty SL, Beckel JM, Carattino MD, Apodaca G., Free PMC Article

    03/19/2022
    Piezo2 downregulation via the Cre-lox system affects aqueous humor dynamics in mice.

    Piezo2 downregulation via the Cre-lox system affects aqueous humor dynamics in mice.
    Fang J, Hou F, Wu S, Liu Y, Wang L, Zhang J, Wang N, Wang K, Zhu W., Free PMC Article

    12/11/2021
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