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    MIR545 microRNA 545 [ Homo sapiens (human) ]

    Gene ID: 664614, updated on 4-Jan-2025

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Long non-coding TRPM2-AS regulates fracture healing by targeting miR-545-3p/Bmp2.

    Long non-coding TRPM2-AS regulates fracture healing by targeting miR-545-3p/Bmp2.
    Kang R, Huang L, Zeng T, Ma J, Jin D., Free PMC Article

    09/18/2024
    Circ_0018909 knockdown inhibits the development of pancreatic cancer via the miR-545-3p/FASN axis and reduces macrophage polarization to M2.

    Circ_0018909 knockdown inhibits the development of pancreatic cancer via the miR-545-3p/FASN axis and reduces macrophage polarization to M2.
    Song Y, Wang J, Xu J, Gao Y, Xu Z.

    04/12/2023
    Knockdown of circ_0038467 alleviates lipopolysaccharides-induced 16HBE cell injury by regulating the miR-545-3p/TRAF1 axis in neonatal pneumonia.

    Knockdown of circ_0038467 alleviates lipopolysaccharides-induced 16HBE cell injury by regulating the miR-545-3p/TRAF1 axis in neonatal pneumonia.
    Xia F, Yang L, Zhu X.

    12/17/2022
    Role of lncRNA FAM83H antisense RNA1 (FAM83H-AS1) in the progression of non-small cell lung cancer by regulating the miR-545-3p/heparan sulfate 6-O-sulfotransferase (HS6ST2) axis.

    Role of lncRNA FAM83H antisense RNA1 (FAM83H-AS1) in the progression of non-small cell lung cancer by regulating the miR-545-3p/heparan sulfate 6-O-sulfotransferase (HS6ST2) axis.
    Zhang Y, Yu Y, Cao X, Chen P., Free PMC Article

    08/6/2022
    AFAP1 antisense RNA 1 promotes retinoblastoma progression by sponging microRNA miR-545-3p that targets G protein subunit beta 1.

    AFAP1 antisense RNA 1 promotes retinoblastoma progression by sponging microRNA miR-545-3p that targets G protein subunit beta 1.
    Tang W, Zhang L, Li J, Guan Y., Free PMC Article

    04/16/2022
    Shikonin induces cell autophagy via modulating the microRNA -545-3p/guanine nucleotide binding protein beta polypeptide 1 axis, thereby disrupting cellular carcinogenesis in colon cancer.

    Shikonin induces cell autophagy via modulating the microRNA -545-3p/guanine nucleotide binding protein beta polypeptide 1 axis, thereby disrupting cellular carcinogenesis in colon cancer.
    Hu Z, Zhou X, Zeng D, Lai J., Free PMC Article

    04/16/2022
    Long non-coding RNA CASC9 promotes tumor progression in oral squamous cell carcinoma by regulating microRNA-545-3p/laminin subunit gamma 2.

    Long non-coding RNA CASC9 promotes tumor progression in oral squamous cell carcinoma by regulating microRNA-545-3p/laminin subunit gamma 2.
    Ning B, Guo S, Mei Y., Free PMC Article

    02/26/2022
    Circular RNA UBR1 promotes the proliferation, migration, and invasion but represses apoptosis of lung cancer cells via modulating microRNA-545-5p/SSFA2 axis.

    Circular RNA UBR1 promotes the proliferation, migration, and invasion but represses apoptosis of lung cancer cells via modulating microRNA-545-5p/SSFA2 axis.
    Su P, Mao F, Zhang J, Zhang H, Wang M, Xu Y, Tian Z., Free PMC Article

    02/19/2022
    Circular RNA intraflagellar transport 80 facilitates endometrial cancer progression through modulating miR-545-3p/FAM98A signaling.

    Circular RNA intraflagellar transport 80 facilitates endometrial cancer progression through modulating miR-545-3p/FAM98A signaling.
    Wang N, Guo Y, Song L, Tong T, Fan X., Free PMC Article

    02/5/2022
    C-X-C motif chemokine 16, modulated by microRNA-545, aggravates myocardial damage and affects the inflammatory responses in myocardial infarction.

    C-X-C motif chemokine 16, modulated by microRNA-545, aggravates myocardial damage and affects the inflammatory responses in myocardial infarction.
    Liang FQ, Gao JY, Liu JW., Free PMC Article

    02/5/2022
    Circular RNA PRKCI and microRNA-545 relate to sepsis risk, disease severity and 28-day mortality.

    Circular RNA PRKCI and microRNA-545 relate to sepsis risk, disease severity and 28-day mortality.
    Wei B, Yu L.

    10/16/2021
    Hypoxia-Induced Epithelial-to-Mesenchymal Transition in Proximal Tubular Epithelial Cells through miR-545-3p-TNFSF10.

    Hypoxia-Induced Epithelial-to-Mesenchymal Transition in Proximal Tubular Epithelial Cells through miR-545-3p-TNFSF10.
    Kuo MC, Chang WA, Wu LY, Tsai YC, Hsu YL., Free PMC Article

    10/9/2021
    Long Non-Coding RNA CASC2 Overexpression Ameliorates Sepsis-Associated Acute Kidney Injury by Regulating MiR-545-3p/PPARA Axis.

    Long Non-Coding RNA CASC2 Overexpression Ameliorates Sepsis-Associated Acute Kidney Injury by Regulating MiR-545-3p/PPARA Axis.
    Hu Q, Zen W, Zhang M, Wang Z, Cui W, Liu Y, Xu B.

    10/2/2021
    MicroRNA-545 suppresses progression of ovarian cancer through mediating PLK1 expression by a direct binding and an indirect regulation involving KDM4B-mediated demethylation.

    MicroRNA-545 suppresses progression of ovarian cancer through mediating PLK1 expression by a direct binding and an indirect regulation involving KDM4B-mediated demethylation.
    Zhang H, Zhang K, Xu Z, Chen Z, Wang Q, Wang C, Cui J., Free PMC Article

    09/11/2021
    LncRNA AFAP1-AS1 contributes to the progression of endometrial carcinoma by regulating miR-545-3p/VEGFA pathway.

    LncRNA AFAP1-AS1 contributes to the progression of endometrial carcinoma by regulating miR-545-3p/VEGFA pathway.
    Zhong Y, Wang Y, Dang H, Wu X.

    07/17/2021
    Long Noncoding RNASBF2-AS1 Promotes Gastric Cancer Progression via Regulating miR-545/EMS1 Axis.

    Long Noncoding RNASBF2-AS1 Promotes Gastric Cancer Progression via Regulating miR-545/EMS1 Axis.
    He M, Feng L, Qi L, Rao M, Zhu Y., Free PMC Article

    04/3/2021
    Downregulation of hsa_circ_0007580 inhibits non-small cell lung cancer tumorigenesis by reducing miR-545-3p sponging.

    Downregulation of hsa_circ_0007580 inhibits non-small cell lung cancer tumorigenesis by reducing miR-545-3p sponging.
    Chen S, Lu S, Yao Y, Chen J, Yang G, Tu L, Zhang Z, Zhang J, Chen L., Free PMC Article

    03/27/2021
    Circular RNA circ-PRKCI promotes cell proliferation and invasion by binding to microRNA-545 in gastric cancer.

    Circular RNA circ-PRKCI promotes cell proliferation and invasion by binding to microRNA-545 in gastric cancer.
    Wu L, Li Y, Xu XM, Zhu X.

    12/19/2020
    circPRKCI promotes human glioma cell progression possibly by inhibiting miR-545.

    Circular RNA PRKCI promotes glioma cell progression by inhibiting microRNA-545.
    Zhang X, Yang H, Zhao L, Li G, Duan Y., Free PMC Article

    08/1/2020
    results show that dysregulation of circPRKCI-miR-545/589-E2F7 axis mediated H2O2-induced neuronal cell injury; targeting this novel cascade could be a fine strategy to protect neurons from oxidative stress

    CircPRKCI-miR-545/589-E2F7 axis dysregulation mediates hydrogen peroxide-induced neuronal cell injury.
    Cheng Q, Cao X, Xue L, Xia L, Xu Y.

    07/11/2020
    LINC00342 was over-expressed in colon adenocarcinoma (COAD) tissues and was related to the poor prognosis. LINC00342 knockdown inhibited cell proliferation, migration and invasion and promoted apoptosis of COAD cells. LINC00342 targeted to miR-545-5p/ MDM2 in COAD. In COAD tissues and cell lines, LINC00342 expression was positively correlated to MDM2 expression, while it was negatively correlated to miR-545-5p expression.

    LINC00342 regulates cell proliferation, apoptosis, migration and invasion in colon adenocarcinoma via miR-545-5p/MDM2 axis.
    Miao Z, Liu S, Xiao X, Li D.

    05/9/2020
    circ_0067934 promotes cervical cancer progression via miR-545/EIF3C axis.

    Overexpressed circ_0067934 acts as an oncogene to facilitate cervical cancer progression via the miR-545/EIF3C axis.
    Hu C, Wang Y, Li A, Zhang J, Xue F, Zhu L.

    04/11/2020
    high expression of miR-545 inhibits EMT in GC and the oncogenic actions of EMS1.

    MiRNA-545 negatively regulates the oncogenic activity of EMS1 in gastric cancer.
    Ma M, Zhao J, Wu Q, Xiao K, Li S, Zhu H, Liu C, Xie H, Zuo C., Free PMC Article

    11/2/2019
    MiR-545-3p, which served as a tumor promoter, post-transcriptionally regulate MT1M in HCC through binding to its untranslated region (3'UTR).

    MiR-545-3p/MT1M axis regulates cell proliferation, invasion and migration in hepatocellular carcinoma.
    Changjun L, Feizhou H, Dezhen P, Zhao L, Xianhai M.

    03/2/2019
    Plasma miR-34a-5p and miR-545-3p may be early biomarkers of Alzheimer's Disease

    Plasma miR-34a-5p and miR-545-3p as Early Biomarkers of Alzheimer's Disease: Potential and Limitations.
    Cosín-Tomás M, Antonell A, Lladó A, Alcolea D, Fortea J, Ezquerra M, Lleó A, Martí MJ, Pallàs M, Sanchez-Valle R, Molinuevo JL, Sanfeliu C, Kaliman P.

    05/19/2018
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