| Effects of osmolality on the expression of brain aquaporins in AQP11-null mice. | Effects of osmolality on the expression of brain aquaporins in AQP11-null mice.
Koike S, Tanaka Y, Morishita Y, Ishibashi K. | 09/4/2021 |
| We conclude that Aqp11(-/-) mice develop cyst-like dilated proximal tubules without documented cysts at time of death. | Temporal deletion of Aqp11 in mice is linked to the severity of cyst-like disease.
Rützler M, Rojek A, Damgaard MV, Andreasen A, Fenton RA, Nielsen S. | 07/8/2017 |
| The results suggest the involvement of autophagy in the development and maintenance of kidney cysts in AQP11(-/-) mice. | Enhanced Autophagy in Polycystic Kidneys of AQP11 Null Mice.
Tanaka Y, Watari M, Saito T, Morishita Y, Ishibashi K., Free PMC Article | 05/13/2017 |
| AQP11 was expressed mainly in the pia matter with limited expression in the capillary at early postnatal stages at P1~P14. | Aquaporin-11 (AQP11) Expression in the Mouse Brain.
Koike S, Tanaka Y, Matsuzaki T, Morishita Y, Ishibashi K., Free PMC Article | 03/25/2017 |
| impaired glycosylation processing and aberrant membrane trafficking of PC-1 in AQP11(-/-) mice could be a key mechanism of cystogenesis in AQP11(-/-) mice | Aberrant glycosylation and localization of polycystin-1 cause polycystic kidney in an AQP11 knockout model.
Inoue Y, Sohara E, Kobayashi K, Chiga M, Rai T, Ishibashi K, Horie S, Su X, Zhou J, Sasaki S, Uchida S., Free PMC Article | 02/28/2015 |
| Our results indicate an important role for AQP11 to prevent glucose-induced oxidative stress in proximal tubules. | Aquaporin 11 insufficiency modulates kidney susceptibility to oxidative stress.
Atochina-Vasserman EN, Biktasova A, Abramova E, Cheng DS, Polosukhin VV, Tanjore H, Takahashi S, Sonoda H, Foye L, Venkov C, Ryzhov SV, Novitskiy S, Shlonimskaya N, Ikeda M, Blackwell TS, Lawson WE, Gow AJ, Harris RC, Dikov MM, Tchekneva EE., Free PMC Article | 07/27/2013 |
| deletion of AQP11 results in disrupted rough endoplasmic reticulum homeostasis and increased sensitivity to rough endoplasmic reticulum injury upon metabolic challenge with amino acid | Liver-specific Aquaporin 11 knockout mice show rapid vacuolization of the rough endoplasmic reticulum in periportal hepatocytes after amino acid feeding.
Rojek A, Füchtbauer EM, Füchtbauer A, Jelen S, Malmendal A, Fenton RA, Nielsen S. | 04/27/2013 |
| mouse aquaporin 11 could be involved in slow but constant water movement across the membrane | Water permeability and characterization of aquaporin-11.
Yakata K, Tani K, Fujiyoshi Y. | 08/20/2011 |
| important role during salivary gland development | Aquaporin 11 in the developing mouse submandibular gland.
Larsen HS, Ruus AK, Schreurs O, Galtung HK. | 05/31/2010 |
| Immunohistochemistry of mouse testis across development pinpointed first appearance of AQP11 coinciding with late stage elongated spermatids. cDNA analysis yielded conformation of sequence. Western blotting revealed additional forms. | Aquaporin AQP11 in the testis: molecular identity and association with the processing of residual cytoplasm of elongated spermatids.
Yeung CH, Cooper TG. | 03/15/2010 |
| These results provide new insights into the physiological roles of AQP11. | Aquaporin-11 knockout mice and polycystic kidney disease animals share a common mechanism of cyst formation.
Okada S, Misaka T, Tanaka Y, Matsumoto I, Ishibashi K, Sasaki S, Abe K. | 01/21/2010 |
| mutation causing single amino acid substitution in aquaporin 11 causes renal failure in sudden juvenile death syndrome mutant mice | Single amino acid substitution in aquaporin 11 causes renal failure.
Tchekneva EE, Khuchua Z, Davis LS, Kadkina V, Dunn SR, Bachman S, Ishibashi K, Rinchik EM, Harris RC, Dikov MM, Breyer MD., Free PMC Article | 01/21/2010 |
| AQP11 is essential for the proximal tubular function | Disruption of aquaporin-11 produces polycystic kidneys following vacuolization of the proximal tubule.
Morishita Y, Matsuzaki T, Hara-chikuma M, Andoo A, Shimono M, Matsuki A, Kobayashi K, Ikeda M, Yamamoto T, Verkman A, Kusano E, Ookawara S, Takata K, Sasaki S, Ishibashi K., Free PMC Article | 01/21/2010 |