| Oxidative stress may contribute to the increase in aortic MMP-2 activity, possibly by S-glutathiolation, and this may result in calponin-1 loss and maladaptive vascular remodeling in early hypertension. | Matrix metalloproteinase (MMP)-2 activation by oxidative stress decreases aortic calponin-1 levels during hypertrophic remodeling in early hypertension.
Blascke de Mello MM, Parente JM, Schulz R, Castro MM. | 09/7/2019 |
| MMP-2 activity is increased in both conductance and resistance arteries in hypertension and contributes to early vascular dysfunction and remodelling. These maladaptive effects were related to the divergent regulation of calponin-1, which is decreased in aortas while is increased in resistance arteries. | Matrix Metalloproteinase-2 Activity is Associated with Divergent Regulation of Calponin-1 in Conductance and Resistance Arteries in Hypertension-induced Early Vascular Dysfunction and Remodelling.
Parente JM, Pereira CA, Oliveira-Paula GH, Tanus-Santos JE, Tostes RC, Castro MM. | 02/3/2018 |
| Actin cytoskeleton depolymerization inhibites BMP2 signaling via blocking of Smad by dephosphorylated CNN1 in osteoblast cells under simulated microgravity. | Actin cytoskeleton mediates BMP2-Smad signaling via calponin 1 in preosteoblast under simulated microgravity.
Xu H, Wu F, Zhang H, Yang C, Li K, Wang H, Yang H, Liu Y, Ding B, Tan Y, Yuan M, Li Y, Dai Z. | 08/12/2017 |
| Data suggest that proteolysis of calponin-1 by Mmp2 (matrix metallopeptidase 2) contributes to the down-regulation of calponin-1 in cytoplasm of endothelium and smooth muscle of aorta/arteries in early (1-week) hypertension; however, at 2-weeks, calponin-1 is up-regulated. | Matrix metalloproteinase (MMP)-2 decreases calponin-1 levels and contributes to arterial remodeling in early hypertension.
Belo VA, Parente JM, Tanus-Santos JE, Castro MM. | 05/6/2017 |
| Calponin 1 is present in the cervix of virgin, 11 day, and 20 day pregnant rats. | The persistence of active smooth muscle in the female rat cervix through pregnancy.
Ferland DJ, Darios ES, Watts SW. | 04/11/2015 |
| Data indicte that desmin and h1-calponin are expressed in mesenchymal stem cells (MSC). | Differentiated markers in undifferentiated cells: expression of smooth muscle contractile proteins in multipotent bone marrow mesenchymal stem cells.
Liu Y, Deng B, Zhao Y, Xie S, Nie R. | 10/26/2013 |
| Calcitonin gene-related peptide significantly upregulated Cnn1 and downregulated OPN in corpus cavernosum smooth muscle cells from diabetic rats with erectile dysfunction. | [Calcitonin gene-related peptide induces phenotypic transformation of corpus cavernosum smooth muscle cells in diabetic rats with erectile dysfunction].
He SH, Wei AY, Ye TY, Yang Y, Luo XG, Liu Y, Zhang T. | 04/21/2012 |
| Calponin-1 is a target of MMP-2, which contributes to endotoxemia-induced vascular hypocontractility. | Matrix metalloproteinase-2 proteolysis of calponin-1 contributes to vascular hypocontractility in endotoxemic rats.
Castro MM, Cena J, Cho WJ, Walsh MP, Schulz R. | 04/14/2012 |
| comparison between the basic C-terminal half of rat nonmuscle CALD1 and calponin, another actin-binding protein that is also basic and has similar actin-regulatory activities | Role of the basic C-terminal half of caldesmon in its regulation of F-actin: comparison between caldesmon and calponin.
Takiguchi K, Matsumura F. | 01/21/2010 |
| the frequency-dependent expression of h1-calponin under cyclic strain is mediated at least partly by the regulation of Rac and Rho-GDI alpha expression on the activation of p38 pathway | Role of Rac and Rho-GDI alpha in the frequency-dependent expression of h1-calponin in vascular smooth muscle cells under cyclic mechanical strain.
Qu MJ, Liu B, Qi YX, Jiang ZL. | 01/21/2010 |
| The molecular basis for the autoregulation of calponin by isoform-specific C-terminal tail sequences | The molecular basis for the autoregulation of calponin by isoform-specific C-terminal tail sequences.
Burgstaller G, Kranewitter WJ, Gimona M. | 01/21/2010 |
| CNh1 plays a role as tumor suppressor in SR-3Y1 mainly by decreasing VEGF expression and angiogenesis in vivo and partially through reducing cellular proliferative potential and cell motility | Calponin h1 suppresses tumor growth of Src-induced transformed 3Y1 cells in association with a decrease in angiogenesis.
Kaneko M, Takeoka M, Oguchi M, Koganehira Y, Murata H, Ehara T, Tozuka M, Saida T, Taniguchi S., Free PMC Article | 01/21/2010 |
| These data, supported by Western blotting, indicate that calponin can not be used to distinguish adult OECs and Schwann cells. | Calponin is expressed by fibroblasts and meningeal cells but not olfactory ensheathing cells in the adult peripheral olfactory system.
Ibanez C, Ito D, Zawadzka M, Jeffery ND, Franklin RJ. | 01/21/2010 |
| Calponin increased in the molecular layer of the dentate gyrus, the site of mossy fiber sprouting, and neo-synaptogenesis, at 1 and 2 weeks after pilocarpine injection, when the reorganization was taking place. | Increased levels of acidic calponin during dendritic spine plasticity after pilocarpine-induced seizures.
Ferhat L, Esclapez M, Represa A, Fattoum A, Shirao T, Ben-Ari Y. | 01/21/2010 |