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    CLEC7A C-type lectin domain containing 7A [ Homo sapiens (human) ]

    Gene ID: 64581, updated on 27-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    CLEC7A regulates M2 macrophages to suppress the immune microenvironment and implies poorer prognosis of glioma.

    CLEC7A regulates M2 macrophages to suppress the immune microenvironment and implies poorer prognosis of glioma.
    Wang J, Li X, Wang K, Li K, Gao Y, Xu J, Peng R, Zhang X, Zhang S, Zhou Y, Xu S, Zhang J., Free PMC Article

    10/29/2024
    Possible role of intestinal fungal dysbiosis in dectin-1 and cytokines expression in patients with ulcerative colitis.

    Possible role of intestinal fungal dysbiosis in dectin-1 and cytokines expression in patients with ulcerative colitis.
    Azizollah N, Sharifinejad N, Mozhgani SH, Mousavian SM, Bakhtiyari M, Mahmoudi E.

    09/25/2024
    Variants of human DECTIN-1 rs16910526 are linked to differential reactive oxygen species production and susceptibility to tuberculosis.

    Variants of human DECTIN-1 rs16910526 are linked to differential reactive oxygen species production and susceptibility to tuberculosis.
    Cufré M, Pastorini M, Martín I, Failde R, Palmero D, Alemán M., Free PMC Article

    09/11/2024
    IL-17A and TNF-alpha-induced Dectin-1 expression may promote keratinocyte proliferation in psoriatic lesions.

    IL-17A and TNF-α-induced Dectin-1 expression may promote keratinocyte proliferation in psoriatic lesions.
    Cui W, Liu J, Kong S, Huang H, Liu L, Cao Y, Gu Z.

    07/11/2024
    Dectin-1 aggravates neutrophil inflammation through caspase-11/4-mediated macrophage pyroptosis in asthma.

    Dectin-1 aggravates neutrophil inflammation through caspase-11/4-mediated macrophage pyroptosis in asthma.
    Cai R, Gong X, Li X, Jiang Y, Deng S, Tang J, Ge H, Wu C, Tang H, Wang G, Xie L, Chen X, Hu X, Feng J., Free PMC Article

    03/13/2024
    Cell-intrinsic C5a synergizes with Dectin-1 in macrophages to mediate fungal killing.

    Cell-intrinsic C5a synergizes with Dectin-1 in macrophages to mediate fungal killing.
    Li XX, Fung JN, Clark RJ, Lee JD, Woodruff TM., Free PMC Article

    02/1/2024
    Dectin-1 ligands produce distinct training phenotypes in human monocytes through differential activation of signaling networks.

    Dectin-1 ligands produce distinct training phenotypes in human monocytes through differential activation of signaling networks.
    Cheng QJ, Farrell K, Fenn J, Ma Z, Makanani SK, Siemsen J., Free PMC Article

    01/29/2024
    DECTIN-1: A modifier protein in CTLA-4 haploinsufficiency.

    DECTIN-1: A modifier protein in CTLA-4 haploinsufficiency.
    Turnbull C, Bones J, Stanley M, Medhavy A, Wang H, Lorenzo AMD, Cappello J, Shanmuganandam S, Pandey A, Seneviratne S, Brown GJ, Meng X, Fulcher D, Burgio G, Man SM, de Lucas Collantes C, Gasior M, López Granados E, Martin P, Jiang SH, Cook MC, Ellyard JI, Athanasopoulos V, Corry B, Canete PF, Vinuesa CG., Free PMC Article

    12/18/2023
    Dectin-1 multimerization and signaling depends on fungal beta-glucan structure and exposure.

    Dectin-1 multimerization and signaling depends on fungal β-glucan structure and exposure.
    Anaya EU, Amin AE, Wester MJ, Danielson ME, Michel KS, Neumann AK., Free PMC Article

    09/27/2023
    Blocking Dectin-1 prevents colorectal tumorigenesis by suppressing prostaglandin E2 production in myeloid-derived suppressor cells and enhancing IL-22 binding protein expression.

    Blocking Dectin-1 prevents colorectal tumorigenesis by suppressing prostaglandin E2 production in myeloid-derived suppressor cells and enhancing IL-22 binding protein expression.
    Tang C, Sun H, Kadoki M, Han W, Ye X, Makusheva Y, Deng J, Feng B, Qiu D, Tan Y, Wang X, Guo Z, Huang C, Peng S, Chen M, Adachi Y, Ohno N, Trombetta S, Iwakura Y., Free PMC Article

    03/23/2023
    Gene expression analysis of toll like receptor 2 and 4, Dectin-1, Osteopontin and inflammatory cytokines in human dental pulp ex-vivo.

    Gene expression analysis of toll like receptor 2 and 4, Dectin-1, Osteopontin and inflammatory cytokines in human dental pulp ex-vivo.
    Hasan A, Roome T, Wahid M, Ansari SA, Akhtar H, Jilani SNA, Kiyani A., Free PMC Article

    12/17/2022
    Human Dectin-1 deficiency impairs macrophage-mediated defense against phaeohyphomycosis.

    Human Dectin-1 deficiency impairs macrophage-mediated defense against phaeohyphomycosis.
    Drummond RA, Desai JV, Hsu AP, Oikonomou V, Vinh DC, Acklin JA, Abers MS, Walkiewicz MA, Anzick SL, Swamydas M, Vautier S, Natarajan M, Oler AJ, Yamanaka D, Mayer-Barber KD, Iwakura Y, Bianchi D, Driscoll B, Hauck K, Kline A, Viall NS, Zerbe CS, Ferré EM, Schmitt MM, DiMaggio T, Pittaluga S, Butman JA, Zelazny AM, Shea YR, Arias CA, Ashbaugh C, Mahmood M, Temesgen Z, Theofiles AG, Nigo M, Moudgal V, Bloch KC, Kelly SG, Whitworth MS, Rao G, Whitener CJ, Mafi N, Gea-Banacloche J, Kenyon LC, Miller WR, Boggian K, Gilbert A, Sincock M, Freeman AF, Bennett JE, Hasbun R, Mikelis CM, Kwon-Chung KJ, Belkaid Y, Brown GD, Lim JK, Kuhns DB, Holland SM, Lionakis MS., Free PMC Article

    11/26/2022
    Dectin-1 as a Potential Inflammatory Biomarker for Metabolic Inflammation in Adipose Tissue of Individuals with Obesity.

    Dectin-1 as a Potential Inflammatory Biomarker for Metabolic Inflammation in Adipose Tissue of Individuals with Obesity.
    Al Madhoun A, Kochumon S, Al-Rashed F, Sindhu S, Thomas R, Miranda L, Al-Mulla F, Ahmad R., Free PMC Article

    10/8/2022
    Epigenetic regulation of epithelial dectin-1 through an IL-33-STAT3 axis in allergic disease.

    Epigenetic regulation of epithelial dectin-1 through an IL-33-STAT3 axis in allergic disease.
    Yong HM, Gour N, Sharma D, Khalil SM, Lane AP, Lajoie S., Free PMC Article

    04/16/2022
    Commensal bacteria and fungi differentially regulate tumor responses to radiation therapy.

    Commensal bacteria and fungi differentially regulate tumor responses to radiation therapy.
    Shiao SL, Kershaw KM, Limon JJ, You S, Yoon J, Ko EY, Guarnerio J, Potdar AA, McGovern DPB, Bose S, Dar TB, Noe P, Lee J, Kubota Y, Maymi VI, Davis MJ, Henson RM, Choi RY, Yang W, Tang J, Gargus M, Prince AD, Zumsteg ZS, Underhill DM., Free PMC Article

    01/8/2022
    Dectin-1 Controls TSLP-Induced Th2 Response by Regulating STAT3, STAT6, and p50-RelB Activities in Dendritic Cells.

    Dectin-1 Controls TSLP-Induced Th2 Response by Regulating STAT3, STAT6, and p50-RelB Activities in Dendritic Cells.
    Gu C, Upchurch K, Horton J, Wiest M, Zurawski S, Millard M, Kane RR, Joo H, Miller LA, Oh S., Free PMC Article

    10/30/2021
    RHOA-mediated mechanical force generation through Dectin-1.

    RHOA-mediated mechanical force generation through Dectin-1.
    Choraghe RP, Kołodziej T, Buser A, Rajfur Z, Neumann AK., Free PMC Article

    08/7/2021
    Interaction Between Dendritic Cells and Candida krusei beta-Glucan Partially Depends on Dectin-1 and It Promotes High IL-10 Production by T Cells.

    Interaction Between Dendritic Cells and Candida krusei β-Glucan Partially Depends on Dectin-1 and It Promotes High IL-10 Production by T Cells.
    Dinh TTH, Tummamunkong P, Padungros P, Ponpakdee P, Boonprakong L, Saisorn W, Leelahavanichkul A, Kueanjinda P, Ritprajak P., Free PMC Article

    07/24/2021
    The relationship between dectin-1 and mast cells in patients with diarrhea-predominant irritable bowel syndrome.

    The relationship between dectin-1 and mast cells in patients with diarrhea-predominant irritable bowel syndrome.
    Chi Y, Li C, Wu LH, Wang HH.

    07/3/2021
    Divergent Roles for Macrophage C-type Lectin Receptors, Dectin-1 and Mannose Receptors, in the Intestinal Inflammatory Response.

    Divergent Roles for Macrophage C-type Lectin Receptors, Dectin-1 and Mannose Receptors, in the Intestinal Inflammatory Response.
    Rahabi M, Jacquemin G, Prat M, Meunier E, AlaEddine M, Bertrand B, Lefèvre L, Benmoussa K, Batigne P, Aubouy A, Auwerx J, Kirzin S, Bonnet D, Danjoux M, Pipy B, Alric L, Authier H, Coste A.

    03/27/2021
    Genetic association analysis of CLEC5A and CLEC7A gene single-nucleotide polymorphisms and Crohn's disease.

    Genetic association analysis of CLEC5A and CLEC7A gene single-nucleotide polymorphisms and Crohn's disease.
    Elleisy N, Rohde S, Huth A, Gittel N, Glass Ä, Möller S, Lamprecht G, Schäffler H, Jaster R., Free PMC Article

    02/13/2021
    Human thioredoxin, a damage-associated molecular pattern and Malassezia-crossreactive autoallergen, modulates immune responses via the C-type lectin receptors Dectin-1 and Dectin-2.

    Human thioredoxin, a damage-associated molecular pattern and Malassezia-crossreactive autoallergen, modulates immune responses via the C-type lectin receptors Dectin-1 and Dectin-2.
    Roesner LM, Ernst M, Chen W, Begemann G, Kienlin P, Raulf MK, Lepenies B, Werfel T., Free PMC Article

    10/31/2020
    Association between dectin-1 gene single nucleotide polymorphisms and fungal infection: a systemic review and meta-analysis.

    Association between dectin-1 gene single nucleotide polymorphisms and fungal infection: a systemic review and meta-analysis.
    Zhou P, Xie Y, Yan Z, Liu X, Hua H., Free PMC Article

    10/31/2020
    Dectin-1 genetic deficiency predicts chronic lung allograft dysfunction and death.

    Dectin-1 genetic deficiency predicts chronic lung allograft dysfunction and death.
    Calabrese DR, Wang P, Chong T, Hoover J, Singer JP, Torgerson D, Hays SR, Golden JA, Kukreja J, Dugger D, Christie JD, LTOG investigators, Greenland JR., Free PMC Article

    10/24/2020
    Dectin-1-induced RIPK1 and RIPK3 activation protects host against Candida albicans infection.

    Dectin-1-induced RIPK1 and RIPK3 activation protects host against Candida albicans infection.
    Cao M, Wu Z, Lou Q, Lu W, Zhang J, Li Q, Zhang Y, Yao Y, Zhao Q, Li M, Zhang H, Qian Y., Free PMC Article

    10/3/2020
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