| Arf1 is a critical regulator of actin dynamics and synaptic function via modulation of PICK1. | The small GTPase Arf1 modulates Arp2/3-mediated actin polymerization via PICK1 to regulate synaptic plasticity.
Rocca DL, Amici M, Antoniou A, Blanco Suarez E, Halemani N, Murk K, McGarvey J, Jaafari N, Mellor JR, Collingridge GL, Hanley JG., Free PMC Article | 10/19/2013 |
| ARF1-dependent trafficking of procathepsin B and the maturation of autophagosomes results in cathepsin B-mediated trypsinogen activation induced by caerulein. | ADP-ribosylation factor 1 protein regulates trypsinogen activation via organellar trafficking of procathepsin B protein and autophagic maturation in acute pancreatitis.
Orlichenko L, Stolz DB, Noel P, Behari J, Liu S, Singh VP., Free PMC Article | 09/29/2012 |
| Egr1 mediates p53-independent c-Myc-induced apoptosis via a noncanonical ARF-dependent transcriptional mechanism | Egr1 mediates p53-independent c-Myc-induced apoptosis via a noncanonical ARF-dependent transcriptional mechanism.
Boone DN, Qi Y, Li Z, Hann SR., Free PMC Article | 02/26/2011 |
| Arf1-GTP-induced tubule formation suggests a function of Arf family proteins in curvature acquisition at sites of vesicle budding. | Arf1-GTP-induced tubule formation suggests a function of Arf family proteins in curvature acquisition at sites of vesicle budding.
Krauss M, Jia JY, Roux A, Beck R, Wieland FT, De Camilli P, Haucke V., Free PMC Article | 01/21/2010 |
| p24A is a regulator of signal-dependent trafficking that controls ARF1-dependent resensitization of PAR-2 | p24A, a type I transmembrane protein, controls ARF1-dependent resensitization of protease-activated receptor-2 by influence on receptor trafficking.
Luo W, Wang Y, Reiser G. | 01/21/2010 |
| ARF1 is active during mitosis and this activity is required for mitotic Golgi fragmentation. | Active ADP-ribosylation factor-1 (ARF1) is required for mitotic Golgi fragmentation.
Xiang Y, Seemann J, Bisel B, Punthambaker S, Wang Y., Free PMC Article | 01/21/2010 |
| Activation of a non-voltage-activated Na(+)-selective current requires Arf1. | Arf-1 (ADP-ribosylation factor-1) is involved in the activation of a mammalian Na+-selective current.
Straube S, Parekh AB., Free PMC Article | 01/21/2010 |
| Arf GTPases are expressed and targeted in a cell- and membrane-specific pattern in kidney epithelial cells in situ. | Differential expression and targeting of endogenous Arf1 and Arf6 small GTPases in kidney epithelial cells in situ.
El-Annan J, Brown D, Breton S, Bourgoin S, Ausiello DA, Marshansky V. | 01/21/2010 |
| ARF1 and ARF6 are both found on peroxisomes, but coatomer recruitment only depends on ARF1-GTP | Binding and functions of ADP-ribosylation factor on mammalian and yeast peroxisomes.
Lay D, L Grosshans B, Heid H, Gorgas K, Just WW. | 01/21/2010 |
| Overexpression of ARF1 increased the assembly of VLDL 2 but not of VLDL 1, whose production was dependent on both anterograde transport and the availability of fatty acids. | Role of ADP ribosylation factor 1 in the assembly and secretion of ApoB-100-containing lipoproteins.
Asp L, Magnusson B, Rutberg M, Li L, Borén J, Olofsson SO. | 01/21/2010 |
| an Arf1-GBF1-Brefeldin A complex is formed and has a longer residence time on Golgi membranes than GBF1 or Arf1 alone | Dynamics of GBF1, a Brefeldin A-sensitive Arf1 exchange factor at the Golgi.
Niu TK, Pfeifer AC, Lippincott-Schwartz J, Jackson CL., Free PMC Article | 01/21/2010 |
| The role of Arf1 in polarization of the Golgi apparatus is established. | The role of ARF1 and rab GTPases in polarization of the Golgi stack.
Bannykh SI, Plutner H, Matteson J, Balch WE. | 01/21/2010 |