| Survivin (BIRC5) regulates bladder fibrosis in a rat model of partial bladder outlet obstruction. | Survivin ( BIRC5 ) regulates bladder fibrosis in a rat model of partial bladder outlet obstruction.
Di X, Jin X, Xiang L, Gao X, Peng L, Wang W, Xiao K, Liu Y, Chen G, Yuan C, Luo D, Li H, Wang K., Free PMC Article | 03/14/2023 |
| Protective effects of 6-gingerol on 6-hydroxydopamine-induced apoptosis in PC12 cells through modulation of SAPK/JNK and survivin activation. | Protective effects of 6-gingerol on 6-hydroxydopamine-induced apoptosis in PC12 cells through modulation of SAPK/JNK and survivin activation.
Rezazadeh-Shojaee FS, Ramazani E, Kasaian J, Tayarani-Najaran Z. | 04/2/2022 |
| Elevated MST1 leads to apoptosis via depletion of YAP1 in cardiomyocytes exposed to high glucose. | Elevated MST1 leads to apoptosis via depletion of YAP1 in cardiomyocytes exposed to high glucose.
Su D, Li Y, Guan L, Li Q, Shi C, Ma X, Song Y., Free PMC Article | 10/2/2021 |
| survivin overexpression in the ischemic boundary zone induced by using an AAV vector has the potential for amelioration of ischemic damage via an antiapoptotic mechanism | Survivin overexpression via adeno-associated virus vector Rh10 ameliorates ischemic damage after middle cerebral artery occlusion in rats.
Sehara Y, Inaba T, Urabe T, Kurosaki F, Urabe M, Kaneko N, Shimazaki K, Kawai K, Mizukami H. | 12/14/2019 |
| YM155, a selective survivin inhibitor, reverses chronic hypoxic pulmonary hypertension in rats via upregulating voltage-gated potassium channels. | YM155, a selective survivin inhibitor, reverses chronic hypoxic pulmonary hypertension in rats via upregulating voltage-gated potassium channels.
Fan Z, Liu B, Zhang S, Liu H, Li Y, Wang D, Liu Y, Li J, Wang N, Liu Y, Zhang B. | 04/22/2019 |
| transformed MSCs express high levels of a p53 mutant that loses the ability to bind survivin gene | Loss of interactions between p53 and survivin gene in mesenchymal stem cells after spontaneous transformation in vitro.
He L, Zhao F, Zheng Y, Wan Y, Song J. | 09/30/2017 |
| Reciprocal regulation of BMF and BIRC5 is linked to Eomes overexpression in colorectal cancer. | Reciprocal regulation of BMF and BIRC5 (Survivin) linked to Eomes overexpression in colorectal cancer.
Wang R, Kang Y, Löhr CV, Fischer KA, Bradford CS, Johnson G, Dashwood WM, Williams DE, Ho E, Dashwood RH., Free PMC Article | 07/29/2017 |
| Cytoplasmic and nuclear immunostaining for bax, caspase-3, calpain-1 and survivin proteins were found in the endometrial epithelium and stromal cells. | Involution dependent changes in distribution and localization of bax, survivin, caspase-3, and calpain-1 in the rat endometrium.
Alan E, Liman N. | 12/24/2016 |
| Survivin contributed to the development and progression of diabetic retinopathy through the HIF-1alpha pathway and become an important progression marker of diabetic retinopathy. | Survivin contributes to the progression of diabetic retinopathy through HIF-1α pathway.
Liu N, Zhao N, Chen L, Cai N., Free PMC Article | 08/13/2016 |
| NAIP and survivin expressions were significantly reduced following varicocele induction when compared to sham animals whereas PDRN-treated rats showed an increase in NAIP and survivin levels. | Role of Inhibitors of Apoptosis Proteins in Testicular Function and Male Fertility: Effects of Polydeoxyribonucleotide Administration in Experimental Varicocele.
Minutoli L, Arena S, Antonuccio P, Romeo C, Bitto A, Magno C, Rinaldi M, Micali A, Irrera N, Pizzino G, Galfo F, Squadrito F, Altavilla D, Marini H., Free PMC Article | 06/11/2016 |
| survivin was significantly downregulated in the rapamycin-treated and rapamycin+Platelet Factor 4-treated group and this was significantly different when compared to controls | Rapamycin and PF4 induce apoptosis by upregulating Bax and down-regulating survivin in MNU-induced breast cancer.
Al-Astani Tengku Din TA, Shamsuddin SH, Idris FM, Ariffin Wan Mansor WN, Abdul Jalal MI, Jaafar H. | 04/2/2016 |
| elevated survivin expression in PBMCs, particularly survivin and CD8, VEGF, and ICAM-1 double-positive PBMCs, may be crucial for good collateral formation in patients with coronary CTO, as confirmed by assessment of a rat model. | Elevated survivin expression in peripheral blood mononuclear cells is central to collateral formation in coronary chronic total occlusion.
Xu Y, Tan X, Wang D, Wang W, Li Y, Wu M, Chen S, Wu Y, Tan C., Free PMC Article | 01/30/2016 |
| increased expression of KLF5 may activate p-Survivin expression and play an important role in the pathogenesis of PH in nitrofen-induced CDH. | Increased pulmonary vascular expression of Krüppel-like factor 5 and activated survivin in experimental congenital diaphragmatic hernia.
Hofmann AD, Takahashi T, Duess JW, Gosemann JH, Puri P. | 08/29/2015 |
| The aryl hydrocarbon receptor-dependent disruption of contact inhibition in rat liver WB-F344 epithelial cells is linked with induction of survivin, but not with inhibition of apoptosis. | The aryl hydrocarbon receptor-dependent disruption of contact inhibition in rat liver WB-F344 epithelial cells is linked with induction of survivin, but not with inhibition of apoptosis.
Svobodová J, Kabátková M, Šmerdová L, Brenerová P, Dvořák Z, Machala M, Vondráček J. | 08/22/2015 |
| Intermittent hypoxia promotes the expressions of hippocampal neuronal HIF-1 and survivin. | [Intermittent hypoxia promotes the expressions of rat hippocampal neuronal hypoxia-inducible factor-1 and survivin].
Wang L, Zhang P, Wang H, Yu J, Zhang M, Han X, Li L, Liu C. | 07/4/2015 |
| macitentan reversed early but not late obstructive PVD in rats. This reversal was associated with the suppression of survivin-related resistance to apoptosis and proliferation of cells in PVD. | Macitentan reverses early obstructive pulmonary vasculopathy in rats: early intervention in overcoming the survivin-mediated resistance to apoptosis.
Shinohara T, Sawada H, Otsuki S, Yodoya N, Kato T, Ohashi H, Zhang E, Saitoh S, Shimpo H, Maruyama K, Komada Y, Mitani Y. | 05/16/2015 |
| No significant differences were found in the promoter region of survivin gene between normal and N-methyl-N-nitrosourea induced colon tumor tissues. | Mutation detection in the promoter region of survivin gene on N-methyl-N-nitrosourea induced colon tumor model in experiment.
Budak M, Korpinar MA, Kalkan T, Tuncel H. | 12/6/2014 |
| IGF-I signaling through a PI3K/Akt/mTORC1 mechanism elevates expression of Survivin and promotes growth of prostate epithelial cells. | Critical role of a survivin/TGF-β/mTORC1 axis in IGF-I-mediated growth of prostate epithelial cells.
Song K, Shankar E, Yang J, Bane KL, Wahdan-Alaswad R, Danielpour D., Free PMC Article | 02/22/2014 |
| These findings indicate that ischemia and estradiol act synergistically to promote activation of STAT3 and STAT3-dependent transcription of survivin in insulted CA1 neurons. | Survivin Is a transcriptional target of STAT3 critical to estradiol neuroprotection in global ischemia.
Sehara Y, Sawicka K, Hwang JY, Latuszek-Barrantes A, Etgen AM, Zukin RS., Free PMC Article | 10/19/2013 |
| A high dose of propofol exposure may destroy the structure of neurons, induce neurodegeneration, increase Caspase-3 activity and inhibit survivin expression in hippocampus of newborn rats in vivo. | [Effects of propofol on expression of hippocampal survivin and Caspase-3 in newborn rats].
Tang XM, Qin Y, Liao CJ, Xie YB, Lan YY. | 03/16/2013 |
| study suggests that low frequency and intensity ultrasound (LFU) can induce apoptosis in vitro and in vivo, and that three signaling proteins, caspase-3, Bcl-2, and survivin, might be involved in LFU-induced apoptosis | Low frequency and intensity ultrasound induces apoptosis of brain glioma in rats mediated by caspase-3, Bcl-2, and survivin.
Zhang Z, Chen J, Chen L, Yang X, Zhong H, Qi X, Bi Y, Xu K. | 01/5/2013 |
| Survivin over-expression in rat mucin depleted foci indicates that this is an early event in colon carcinogenesis. | Sustained proliferation and resistance to apoptosis after a cytotoxic insult are early alterations in rat colon carcinogenesis.
Femia AP, Salvianti F, Luceri C, Dolara P, Salvadori M, Pinzani P, Caderni G. | 08/4/2012 |
| Results suggest that the Id1/PI3K/Akt/NFkappaB/survivin signalling pathway plays a critical role in endothelial progenitor cell proliferation. | An essential role for the Id1/PI3K/Akt/NFkB/survivin signalling pathway in promoting the proliferation of endothelial progenitor cells in vitro.
Li W, Wang H, Kuang CY, Zhu JK, Yu Y, Qin ZX, Liu J, Huang L., Free PMC Article | 07/7/2012 |
| survivin is involved in regulating the meiotic cell cycle in rat oocytes | Survivin is a critical regulator of spindle organization and chromosome segregation during rat oocyte meiotic maturation.
Wang K, Jiang GJ, Wei L, Liang XW, Miao DQ, Sun SC, Guo L, Wang ZB, Lu SS. | 06/16/2012 |
| Survivin is involved in the anti-apoptotic effect of 2-methoxyestradiol treatment, which may up-regulate survivin expression following global ischemia. | HIF-1-α and survivin involved in the anti-apoptotic effect of 2ME2 after global ischemia in rats.
Li Y, Xia ZL, Chen LB. | 05/19/2012 |