| A novel SALL1 C757T mutation in a Chinese family causes a rare disease --Townes-Brocks syndrome. | A novel SALL1 C757T mutation in a Chinese family causes a rare disease --Townes-Brocks syndrome.
Chi Y, Yao Y, Sun F, Zhang W, Zhang Z, Wang Y, Hao W., Free PMC Article | 09/5/2024 |
| miR-4286 promotes prostate cancer progression by targeting the expression of SALL1. | miR-4286 promotes prostate cancer progression by targeting the expression of SALL1.
Li Z, Zhao S, Wang H, Zhang B, Zhang P. | 07/19/2023 |
| Chromosomal Microarray Analysis Identifies a Novel SALL1 Deletion, Supporting the Association of Haploinsufficiency with a Mild Phenotype of Townes-Brocks Syndrome. | Chromosomal Microarray Analysis Identifies a Novel SALL1 Deletion, Supporting the Association of Haploinsufficiency with a Mild Phenotype of Townes-Brocks Syndrome.
Innoceta AM, Olivucci G, Parmeggiani G, Scarano E, Pragliola A, Graziano C., Free PMC Article | 03/2/2023 |
| Townes-Brocks syndrome with craniosynostosis in two siblings. | Townes-Brocks syndrome with craniosynostosis in two siblings.
Lugli L, Rossi C, Ceccarelli PL, Calabrese O, Bedetti L, Miselli F, Bianchini MA, Iughetti L, Berardi A. | 11/26/2022 |
| Hsa_circ_0043265 Restrains Cell Proliferation, Migration and Invasion of Tongue Squamous Cell Carcinoma via Targeting the miR-1243/SALL1 Axis. | Hsa_circ_0043265 Restrains Cell Proliferation, Migration and Invasion of Tongue Squamous Cell Carcinoma via Targeting the miR-1243/SALL1 Axis.
Qian C, Yang Y, Lan T, Wang Y, Yao J., Free PMC Article | 12/25/2021 |
| SOX2/SALL4 stemness axis modulates Notch signaling genes to maintain self-renewal capacity of esophageal squamous cell carcinoma. | SOX2/SALL4 stemness axis modulates Notch signaling genes to maintain self-renewal capacity of esophageal squamous cell carcinoma.
Forghanifard MM, Kasebi P, Abbaszadegan MR. | 07/24/2021 |
| In human glioblastoma cells and cerebral glioma tissues, SALL1 acted as a tumor suppressor gene by inhibiting Wnt/ss-catenin signaling. | Spalt-Like Transcription Factor 1 (SALL1) Gene Expression Inhibits Cell Proliferation and Cell Migration of Human Glioma Cells Through the Wnt/β-Catenin Signaling Pathway.
Chi D, Zhang W, Jia Y, Cong D, Hu S., Free PMC Article | 01/25/2020 |
| Data identified SALL1 as a novel tumor suppressor in breast cancer. SALL1 can induce tumor cell senescence as a novel mechanism of tumor suppressor function. This molecular process acts through NuRD recruitment and is controlled by the MAPK and mTOR signaling pathways. | SALL1 functions as a tumor suppressor in breast cancer by regulating cancer cell senescence and metastasis through the NuRD complex.
Ma C, Wang F, Han B, Zhong X, Si F, Ye J, Hsueh EC, Robbins L, Kiefer SM, Zhang Y, Hunborg P, Varvares MA, Rauchman M, Peng G., Free PMC Article | 08/3/2019 |
| SALL1 mutations might cause Townes-Brocks Syndrome. | Truncated SALL1 Impedes Primary Cilia Function in Townes-Brocks Syndrome.
Bozal-Basterra L, Martín-Ruíz I, Pirone L, Liang Y, Sigurðsson JO, Gonzalez-Santamarta M, Giordano I, Gabicagogeascoa E, de Luca A, Rodríguez JA, Wilkie AOM, Kohlhase J, Eastwood D, Yale C, Olsen JV, Rauchman M, Anderson KV, Sutherland JD, Barrio R., Free PMC Article | 12/22/2018 |
| Inhibition of SALL1 correlates with reduced levels of CDH1, an important contributor to epithelial-to-mesenchymal transition. | An in vivo RNAi screen identifies SALL1 as a tumor suppressor in human breast cancer with a role in CDH1 regulation.
Wolf J, Müller-Decker K, Flechtenmacher C, Zhang F, Shahmoradgoli M, Mills GB, Hoheisel JD, Boettcher M., Free PMC Article | 10/18/2014 |
| quantity and quality of SALL1 transcript are important for SALL1 function and determine phenotype, and mode of inheritance, of allelic SALL1-related disorders | Homozygous SALL1 mutation causes a novel multiple congenital anomaly-mental retardation syndrome.
Vodopiutz J, Zoller H, Fenwick AL, Arnhold R, Schmid M, Prayer D, Müller T, Repa A, Pollak A, Aufricht C, Wilkie AO, Janecke AR., Free PMC Article | 04/27/2013 |
| report on a family with features of TBS in whom a novel 149 kb deletion spanning the SALL1 gene was identified by high resolution cytogenetics SNP microarray | Implications for genotype-phenotype predictions in Townes-Brocks syndrome: case report of a novel SALL1 deletion and review of the literature.
Miller EM, Hopkin R, Bao L, Ware SM. | 06/9/2012 |
| novel role for Sall1 as a member of the transcriptional network that regulates stem cell pluripotency | Sall1 regulates embryonic stem cell differentiation in association with nanog.
Karantzali E, Lekakis V, Ioannou M, Hadjimichael C, Papamatheakis J, Kretsovali A., Free PMC Article | 03/5/2011 |
| Observational study of gene-disease association. (HuGE Navigator) | Maternal genes and facial clefts in offspring: a comprehensive search for genetic associations in two population-based cleft studies from Scandinavia.
Jugessur A, Shi M, Gjessing HK, Lie RT, Wilcox AJ, Weinberg CR, Christensen K, Boyles AL, Daack-Hirsch S, Nguyen TT, Christiansen L, Lidral AC, Murray JC., Free PMC Article | 09/15/2010 |
| Sall1 induces angiogenesis by stimulating VEGF-A promoter activity. | Zinc-finger transcriptional factor Sall1 induces angiogenesis by activation of the gene for VEGF-A.
Yamamoto C, Fukuda N, Matsumoto T, Higuchi T, Ueno T, Matsumoto K. | 05/3/2010 |
| Studies indicate that vertebrate sal orthologues (spalt-like/sall) have important developmental roles during neural development and organogenesis and gentic diseases. | Regulation and function of Spalt proteins during animal development.
de Celis JF, Barrio R. | 03/22/2010 |
| Data demonstrate that stem cell protein SALL4 represses its target genes, PTEN and SALL1, through the epigenetic repressor Mi-2/NuRD complex. | Stem cell factor SALL4 represses the transcriptions of PTEN and SALL1 through an epigenetic repressor complex.
Lu J, Jeong HW, Kong N, Yang Y, Carroll J, Luo HR, Silberstein LE, Yupoma, Chai L., Free PMC Article | 01/21/2010 |
| Familial transmission of Goldenhar syndrome is not due to mutations in SALL1. | Familial transmission of oculoauriculovertebral spectrum (Goldenhar syndrome) is not due to mutations in either EYA1 or SALL1.
Goodin K, Prucka S, Woolley AL, Kohlhase J, Smith RJ, Grant J, Robin NH. | 01/21/2010 |
| This case increases the demand to examine all children with Townes-Brocks Syndrome (TBS) for ophthalmic abnormalities. | The association of an epibulbar dermoid and Duane syndrome in a patient with a SALL1 mutation (Townes-Brocks Syndrome).
Barry JS, Reddy MA. | 01/21/2010 |
| truncated SALL1 protein is expressed in cells derived from a TBS patient | SALL1 truncated protein expression in Townes-Brocks syndrome leads to ectopic expression of downstream genes.
Kiefer SM, Robbins L, Barina A, Zhang Z, Rauchman M. | 01/21/2010 |
| analysis of one sporadic case of Townes-Brocks syndrome for SALL1 gene mutations and review of the literature [review] | Two coding single nucleotide polymorphisms in the SALL1 gene in Townes-Brocks syndrome: a case report and review of the literature.
Liang Y, Shen D, Cai W. | 01/21/2010 |
| SALL1 gene, mutations of which result in the Townes-Brocks phenotype, is expressed in the developing kidney. | Kidney failure in Townes-Brocks syndrome: an under recognized phenomenon?
Reardon W, Casserly LF, Birkenhäger R, Kohlhase J. | 01/21/2010 |
| SALL1 and GLI3 may have roles in limb malformation and are affected by nonsense-mediated decay | Nonsense-mediated decay and the molecular pathogenesis of mutations in SALL1 and GLI3.
Furniss D, Critchley P, Giele H, Wilkie AO. | 01/21/2010 |
| There is an enhancer element in the SALL1 gene. | Identification of a prosencephalic-specific enhancer of SALL1: comparative genomic approach using the chick embryo.
Izumi K, Aramaki M, Kimura T, Naito Y, Udaka T, Uchikawa M, Kondoh H, Suzuki H, Cho G, Okada Y, Takahashi T, Golden JA, Kosaki K. | 01/21/2010 |
| Sall1 is essential for ureteric bud invasion, the initial key step for metanephros development | Essential roles of Sall1 in kidney development.
Nishinakamura R, Takasato M. | 01/21/2010 |