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    RXRA retinoid X receptor alpha [ Homo sapiens (human) ]

    Gene ID: 6256, updated on 27-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    ZNF148 inhibits HBV replication by downregulating RXRalpha transcription.

    ZNF148 inhibits HBV replication by downregulating RXRα transcription.
    Yao X, Xu K, Tao N, Cheng S, Chen H, Zhang D, Yang M, Tan M, Yu H, Chen P, Zhan Z, He S, Li R, Wang C, Wu D, Ren J., Free PMC Article

    06/25/2024
    Linc-ROR inhibits NK cell-killing activity by promoting RXRA ubiquitination and reducing MICB expression in gastric cancer patients.

    Linc-ROR inhibits NK cell-killing activity by promoting RXRA ubiquitination and reducing MICB expression in gastric cancer patients.
    Niu Q, Li Z, Jiang H, Hu B.

    02/20/2024
    Stationary-to-migratory transition in glioblastoma stem-like cells driven by a fatty acid-binding protein 7-RXRalpha neurogenic pathway.

    Stationary-to-migratory transition in glioblastoma stem-like cells driven by a fatty acid-binding protein 7-RXRα neurogenic pathway.
    Liu RZ, Choi WS, Jain S, Xu X, Elsherbiny ME, Glubrecht DD, Tessier AG, Easaw JC, Fallone BG, Godbout R., Free PMC Article

    12/22/2023
    SNP rs11185644 in RXRA gene and SNP rs2235544 in DIO1 gene predict dosage requirements in a cross-sectional sample of hypothyroid patients.

    SNP rs11185644 in RXRA gene and SNP rs2235544 in DIO1 gene predict dosage requirements in a cross-sectional sample of hypothyroid patients.
    AlEjielat R, Khaleel A, Batarseh YS, Abu-Qatouseh L, Al-Wawi S, AlSunna T., Free PMC Article

    08/16/2023
    lncRNA RMST suppresses the progression of colorectal cancer by competitively binding to miR-27a-3p/RXRalpha axis and inactivating Wnt signaling pathway.

    lncRNA RMST suppresses the progression of colorectal cancer by competitively binding to miR-27a-3p/RXRα axis and inactivating Wnt signaling pathway.
    Chen S, Ji L, Wang Y, Zhang L, Xu M, Su Y, Zhang X., Free PMC Article

    06/26/2023
    Computational refinement identifies functional destructive single nucleotide polymorphisms associated with human retinoid X receptor gene.

    Computational refinement identifies functional destructive single nucleotide polymorphisms associated with human retinoid X receptor gene.
    Sarkar S, Gupta VK, Sharma S, Shen T, Gupta V, Mirzaei M, Graham SL, Chitranshi N.

    01/21/2023
    Integrated analysis of mRNA-seq and miRNA-seq reveals the potential roles of Egr1, Rxra and Max in kidney stone disease.

    Integrated analysis of mRNA-seq and miRNA-seq reveals the potential roles of Egr1, Rxra and Max in kidney stone disease.
    Huang L, Shi Y, Hu J, Ding J, Guo Z, Yu B.

    12/31/2022
    Cytoplasmic Colocalization of RXRalpha and PPARgamma as an Independent Negative Prognosticator for Breast Cancer Patients.

    Cytoplasmic Colocalization of RXRα and PPARγ as an Independent Negative Prognosticator for Breast Cancer Patients.
    Shao W, Köpke MB, Vilsmaier T, Zati Zehni A, Kessler M, Sixou S, Schneider M, Ditsch N, Cavaillès V, Jeschke U., Free PMC Article

    07/23/2022
    The role of resveratrol, Sirtuin1 and RXRalpha as prognostic markers in ovarian cancer.

    The role of resveratrol, Sirtuin1 and RXRα as prognostic markers in ovarian cancer.
    Chen F, Kolben T, Meister S, Czogalla B, Kolben TM, Hester A, Burges A, Trillsch F, Schmoeckel E, Mayr D, Mayerhofer A, Mahner S, Jeschke U, Beyer S., Free PMC Article

    06/11/2022
    Genetic variant of RXR involved in the vitamin D metabolic pathway was linked to HCV infection outcomes among a high-risk Chinese population.

    Genetic variant of RXR involved in the vitamin D metabolic pathway was linked to HCV infection outcomes among a high-risk Chinese population.
    Zhang R, Fu Z, Fan H, Tian T, Wu M, Xie C, Huang P, Yu R, Zhang Y, Zhang W, Wang J.

    02/12/2022
    Association between functional genetic variants in retinoid X receptor-alpha/gamma and the risk of gestational diabetes mellitus in a southern Chinese population.

    Association between functional genetic variants in retinoid X receptor-α/γ and the risk of gestational diabetes mellitus in a southern Chinese population.
    Yu XY, Song LP, Zheng HT, Wei SD, Wen XL, Huang B, Liu DB., Free PMC Article

    02/5/2022
    Prospecting the therapeutic edge of a novel compound (B12) over berberine in the selective targeting of Retinoid X Receptor in colon cancer.

    Prospecting the therapeutic edge of a novel compound (B12) over berberine in the selective targeting of Retinoid X Receptor in colon cancer.
    Subair TI, Soremekun OS, Olotu FA, Soliman MES.

    01/1/2022
    Regulation of Epigenetic Modifications in the Placenta during Preeclampsia: PPARgamma Influences H3K4me3 and H3K9ac in Extravillous Trophoblast Cells.

    Regulation of Epigenetic Modifications in the Placenta during Preeclampsia: PPARγ Influences H3K4me3 and H3K9ac in Extravillous Trophoblast Cells.
    Meister S, Hahn L, Beyer S, Paul C, Mitter S, Kuhn C, von Schönfeldt V, Corradini S, Sudan K, Schulz C, Kolben TM, Mahner S, Jeschke U, Kolben T., Free PMC Article

    12/18/2021
    EGR1 and RXRA transcription factors link TGF-beta pathway and CCL2 expression in triple negative breast cancer cells.

    EGR1 and RXRA transcription factors link TGF-β pathway and CCL2 expression in triple negative breast cancer cells.
    Gorbacheva AM, Uvarova AN, Ustiugova AS, Bhattacharyya A, Korneev KV, Kuprash DV, Mitkin NA., Free PMC Article

    11/6/2021
    Bexarotene combined with lapatinib for the treatment of Cushing's disease: evidence based on drug repositioning and experimental confirmation.

    Bexarotene combined with lapatinib for the treatment of Cushing's disease: evidence based on drug repositioning and experimental confirmation.
    Yu H, Ren S, Wang J, Lv T, Sun L, Du G., Free PMC Article

    10/9/2021
    TET1 promotes RXRalpha expression and adipogenesis through DNA demethylation.

    TET1 promotes RXRα expression and adipogenesis through DNA demethylation.
    Qian H, Zhao J, Yang X, Wu S, An Y, Qu Y, Li Z, Ge H, Li E, Qi W.

    09/18/2021
    Prognostic value of the miRNA-27a and PPAR/RXRalpha signaling axis in patients with thyroid carcinoma.

    Prognostic value of the miRNA-27a and PPAR/RXRα signaling axis in patients with thyroid carcinoma.
    Toraih EA, Fawzy MS, Abushouk AI, Shaheen S, Hobani YH, Alruwetei AM, A Mansouri O, Kandil E, Badran DI.

    09/18/2021
    Heterodimer formation with retinoic acid receptor RXRalpha modulates coactivator recruitment by peroxisome proliferator-activated receptor PPARgamma.

    Heterodimer formation with retinoic acid receptor RXRα modulates coactivator recruitment by peroxisome proliferator-activated receptor PPARγ.
    Kilu W, Merk D, Steinhilber D, Proschak E, Heering J., Free PMC Article

    08/28/2021
    Characterization of a novel HDAC/RXR/HtrA1 signaling axis as a novel target to overcome cisplatin resistance in human non-small cell lung cancer.

    Characterization of a novel HDAC/RXR/HtrA1 signaling axis as a novel target to overcome cisplatin resistance in human non-small cell lung cancer.
    Wang W, Zhao M, Cui L, Ren Y, Zhang J, Chen J, Jia L, Zhang J, Yang J, Chen G, Ashby CR Jr, Wu C, Chen ZS, Wang L., Free PMC Article

    06/12/2021
    Centrosomal Localization of RXRalpha Promotes PLK1 Activation and Mitotic Progression and Constitutes a Tumor Vulnerability.

    Centrosomal Localization of RXRα Promotes PLK1 Activation and Mitotic Progression and Constitutes a Tumor Vulnerability.
    Xie G, Zhou Y, Tu X, Ye X, Xu L, Xiao Z, Wang Q, Wang X, Du M, Chen Z, Chi X, Zhang X, Xia J, Zhang X, Zhou Y, Li Z, Xie C, Sheng L, Zeng Z, Zhou H, Yin Z, Su Y, Xu Y, Zhang XK.

    03/20/2021
    Promotion of cell autophagy and apoptosis in cervical cancer by inhibition of long noncoding RNA LINC00511 via transcription factor RXRA-regulated PLD1.

    Promotion of cell autophagy and apoptosis in cervical cancer by inhibition of long noncoding RNA LINC00511 via transcription factor RXRA-regulated PLD1.
    Shi Y, Liu M, Huang Y, Zhang J, Yin L.

    03/6/2021
    DNA methylation at CpG island shore and RXRalpha regulate NR2F2 in heart tissues of tetralogy of Fallot patients.

    DNA methylation at CpG island shore and RXRα regulate NR2F2 in heart tissues of tetralogy of Fallot patients.
    Xiaodi L, Ming Y, Hongfei X, Yanjie Z, Ruoyi G, Ma X, Wei S, Guoying H.

    02/13/2021
    Agonist binding directs dynamic competition among nuclear receptors for heterodimerization with retinoid X receptor.

    Agonist binding directs dynamic competition among nuclear receptors for heterodimerization with retinoid X receptor.
    Fadel L, Rehó B, Volkó J, Bojcsuk D, Kolostyák Z, Nagy G, Müller G, Simandi Z, Hegedüs É, Szabó G, Tóth K, Nagy L, Vámosi G., Free PMC Article

    01/16/2021
    Downregulation of OCTN2 by cytokines plays an important role in the progression of inflammatory bowel disease.

    Downregulation of OCTN2 by cytokines plays an important role in the progression of inflammatory bowel disease.
    Li P, Wang Y, Luo J, Zeng Q, Wang M, Bai M, Zhou H, Wang J, Jiang H.

    12/5/2020
    Retinoid X receptor alpha is a spatiotemporally predominant therapeutic target for anthracycline-induced cardiotoxicity.

    Retinoid X receptor alpha is a spatiotemporally predominant therapeutic target for anthracycline-induced cardiotoxicity.
    Ma X, Zhu P, Ding Y, Zhang H, Qiu Q, Dvornikov AV, Wang Z, Kim M, Wang Y, Lowerison M, Yu Y, Norton N, Herrmann J, Ekker SC, Hsiai TK, Lin X, Xu X., Free PMC Article

    11/21/2020
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