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    ABCE1 ATP binding cassette subfamily E member 1 [ Homo sapiens (human) ]

    Gene ID: 6059, updated on 27-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Restoration of miR-299-3p promotes macrophage phagocytosis and suppresses malignant phenotypes in breast cancer carcinogenesis via dual-targeting CD47 and ABCE1.

    Restoration of miR-299-3p promotes macrophage phagocytosis and suppresses malignant phenotypes in breast cancer carcinogenesis via dual-targeting CD47 and ABCE1.
    Tong S, Zhu Y, Leng Y, Wu Y, Xiao X, Zhao W, Tan S.

    03/27/2024
    ABCE1 selectively promotes HIF-1alpha transactivation of angiogenic gene expression.

    ABCE1 selectively promotes HIF-1α transactivation of angiogenic gene expression.
    Sun L, Ding X, Kang YJ.

    11/8/2023
    A pan-cancer analysis of the oncogenic role of ATP binding cassette subfamily E member 1 (ABCE1) in human tumors: An observational study.

    A pan-cancer analysis of the oncogenic role of ATP binding cassette subfamily E member 1 (ABCE1) in human tumors: An observational study.
    Yu J, Ma H, He J, Wang M, Yu B, Ge S, Dai Z., Free PMC Article

    12/3/2022
    The Expression and Effect of ABCE1 in Gastric Adenocarcinoma.

    The Expression and Effect of ABCE1 in Gastric Adenocarcinoma.
    Xing L, Sun C, Han L, Zhu Z.

    10/29/2022
    Human ABCE1 exhibits temperature-dependent heterologous co-functionality in S. cerevisiae.

    Human ABCE1 exhibits temperature-dependent heterologous co-functionality in S. cerevisiae.
    Wada M, Ito K., Free PMC Article

    10/8/2022
    FOXO3a-dependent Parkin regulates the development of gastric cancer by targeting ATP-binding cassette transporter E1.

    FOXO3a-dependent Parkin regulates the development of gastric cancer by targeting ATP-binding cassette transporter E1.
    Ding D, Ao X, Li M, Miao S, Liu Y, Lin Z, Wang M, He Y, Wang J.

    09/25/2021
    ABCE1 Regulates RNase L-Induced Autophagy during Viral Infections.

    ABCE1 Regulates RNase L-Induced Autophagy during Viral Infections.
    Ramnani B, Manivannan P, Jaggernauth S, Malathi K., Free PMC Article

    08/14/2021
    MicroRNA145 promotes the apoptosis of leukemic stem cells and enhances drugresistant K562/ADM cell sensitivity to adriamycin via the regulation of ABCE1.

    MicroRNA‑145 promotes the apoptosis of leukemic stem cells and enhances drug‑resistant K562/ADM cell sensitivity to adriamycin via the regulation of ABCE1.
    Wuxiao Z, Wang H, Su Q, Zhou H, Hu M, Tao S, Xu L, Chen Y, Hao X., Free PMC Article

    07/3/2021
    Ribosome Recycling by ABCE1 Links Lysosomal Function and Iron Homeostasis to 3' UTR-Directed Regulation and Nonsense-Mediated Decay.

    Ribosome Recycling by ABCE1 Links Lysosomal Function and Iron Homeostasis to 3' UTR-Directed Regulation and Nonsense-Mediated Decay.
    Zhu X, Zhang H, Mendell JT., Free PMC Article

    05/1/2021
    A structural inventory of native ribosomal ABCE1-43S pre-initiation complexes.

    A structural inventory of native ribosomal ABCE1-43S pre-initiation complexes.
    Kratzat H, Mackens-Kiani T, Ameismeier M, Potocnjak M, Cheng J, Dacheux E, Namane A, Berninghausen O, Herzog F, Fromont-Racine M, Becker T, Beckmann R., Free PMC Article

    04/24/2021
    ABCE1 Acts as a Positive Regulator of Exogenous RNA Decay.

    ABCE1 Acts as a Positive Regulator of Exogenous RNA Decay.
    Nogimori T, Ogami K, Oishi Y, Goda R, Hosoda N, Kitamura Y, Kitade Y, Hoshino SI., Free PMC Article

    02/20/2021
    Suppression of ABCE1-Mediated mRNA Translation Limits N-MYC-Driven Cancer Progression.

    Suppression of ABCE1-Mediated mRNA Translation Limits N-MYC-Driven Cancer Progression.
    Gao J, Jung M, Mayoh C, Venkat P, Hannan KM, Fletcher JI, Kamili A, Gifford AJ, Kusnadi EP, Pearson RB, Hannan RD, Haber M, Norris MD, Somers K, Henderson MJ.

    01/16/2021
    Readthrough of stop codons under limiting ABCE1 concentration involves frameshifting and inhibits nonsense-mediated mRNA decay.

    Readthrough of stop codons under limiting ABCE1 concentration involves frameshifting and inhibits nonsense-mediated mRNA decay.
    Annibaldis G, Domanski M, Dreos R, Contu L, Carl S, Kläy N, Mühlemann O., Free PMC Article

    11/21/2020
    Long noncoding RNA FAM201A mediates the metastasis of lung squamous cell cancer via regulating ABCE1 expression.

    Long noncoding RNA FAM201A mediates the metastasis of lung squamous cell cancer via regulating ABCE1 expression.
    He W, Qiao ZX, Ma B.

    11/21/2020
    Ribosome recycling in mRNA translation, quality control, and homeostasis.

    Ribosome recycling in mRNA translation, quality control, and homeostasis.
    Nürenberg-Goloub E, Tampé R.

    08/22/2020
    Damage-induced ubiquitination of ABCE1 protein by NOT4 generates poly-ubiquitin signals that attract autophagy receptors to mitochondrial outer membrane to initiate mitophagy.

    Ubiquitination of ABCE1 by NOT4 in Response to Mitochondrial Damage Links Co-translational Quality Control to PINK1-Directed Mitophagy.
    Wu Z, Wang Y, Lim J, Liu B, Li Y, Vartak R, Stankiewicz T, Montgomery S, Lu B., Free PMC Article

    09/21/2019
    This study demonstrated that ABCE1 was up-regulated in glioma tissues and cell lines. Down-regulation of ABCE1 inhibited temozolomide resistance of glioma cells in vitro and in vivo. The PI3K/Akt/NF-kappaB pathway was involved in ABCE1-mediated chemoresistance of glioma cells.

    Down-regulation of ABCE1 inhibits temozolomide resistance in glioma through the PI3K/Akt/NF-κB signaling pathway.
    Zhang P, Chen XB, Ding BQ, Liu HL, He T., Free PMC Article

    08/3/2019
    This study highlights the role of ABCE1 as a host factor required for efficient paramyxovirus and pneumovirus translation.

    Comparative Loss-of-Function Screens Reveal ABCE1 as an Essential Cellular Host Factor for Efficient Translation of Paramyxoviridae and Pneumoviridae.
    Anderson DE, Pfeffermann K, Kim SY, Sawatsky B, Pearson J, Kovtun M, Corcoran DL, Krebs Y, Sigmundsson K, Jamison SF, Yeo ZZJ, Rennick LJ, Wang LF, Talbot PJ, Duprex WP, Garcia-Blanco MA, von Messling V., Free PMC Article

    07/6/2019
    Induction of ribosome rescue factors PELO and HBS1L is required to support protein synthesis when ABCE1 levels fall in platelets, including for hemoglobin production during blood cell development.

    Dynamic Regulation of a Ribosome Rescue Pathway in Erythroid Cells and Platelets.
    Mills EW, Wangen J, Green R, Ingolia NT., Free PMC Article

    11/18/2017
    ABCE1 is involved in histone biosynthesis and DNA replication and therefore is essential for normal S phase progression.

    ABCE1 is essential for S phase progression in human cells.
    Toompuu M, Kärblane K, Pata P, Truve E, Sarmiento C., Free PMC Article

    06/24/2017
    The present study reported on the effects of ABCE1 overexpression on lung adenocarcinoma cells in vitro, demonstrating its enhancing effect on cell proliferation and invasiveness with simultaneous downregulation of p27 protein expression.

    Expression of ATP binding cassette E1 enhances viability and invasiveness of lung adenocarcinoma cells in vitro.
    Tian Y, Tian X, Han X, Chen Y, Song CY, Zhang YB, Tian DL.

    04/8/2017
    ABCE1 plays an essential role in the progression and metastasis of lung cancers and may represent a valuable therapeutic target for the management of lung tumor

    ABCE1 plays an essential role in lung cancer progression and metastasis.
    Tian Y, Tian X, Han X, Chen Y, Song CY, Jiang WJ, Tian DL.

    02/18/2017
    miR-299-3p promotes the sensibility of lung cancer to doxorubicin through suppression of ABCE1, at least partly. Therefore, the disordered decreased of miR-299-3p and resulting ABCE1 up-expression may contribute to chemoresistance of lung cancer

    MicroRNA-299-3p promotes the sensibility of lung cancer to doxorubicin through directly targeting ABCE1.
    Zheng D, Dai Y, Wang S, Xing X., Free PMC Article

    10/8/2016
    Expression of the ABCE1-silencing gene, transfected by electrotransfer, could inhibit the proliferation, invasion, and migration of thyroid cancer cells.

    Effect of ABCE1-silencing gene, transfected by electrotransfer, on the proliferation, invasion, and migration of human thyroid carcinoma SW579 cells.
    Qu X, Zhang L.

    09/3/2016
    Downregulation of ABCE1 via siRNA affects the sensitivity of lung cancer cells against chemotherapeutic agents.

    Downregulation of ABCE1 via siRNA affects the sensitivity of A549 cells against chemotherapeutic agents.
    Kara G, Tuncer S, Türk M, Denkbaş EB.

    03/19/2016
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