| Genetic polymorphisms of BACH2, a key gene regulating Th2 immune response, increasing risk of allergic rhinitis. | Genetic polymorphisms of BACH2, a key gene regulating Th2 immune response, increasing risk of allergic rhinitis.
Li X, Gao H, Liu L, Yang Y, Sun S, Liu Y. | 09/16/2024 |
| BACH2 regulates diversification of regulatory and proinflammatory chromatin states in TH17 cells. | BACH2 regulates diversification of regulatory and proinflammatory chromatin states in T(H)17 cells.
Thakore PI, Schnell A, Huang L, Zhao M, Hou Y, Christian E, Zaghouani S, Wang C, Singh V, Singaraju A, Krishnan RK, Kozoriz D, Ma S, Sankar V, Notarbartolo S, Buenrostro JD, Sallusto F, Patsopoulos NA, Rozenblatt-Rosen O, Kuchroo VK, Regev A. | 09/10/2024 |
| Intergenic risk variant rs56258221 skews the fate of naive CD4[+] T cells via miR4464-BACH2 interplay in primary sclerosing cholangitis. | Intergenic risk variant rs56258221 skews the fate of naive CD4(+) T cells via miR4464-BACH2 interplay in primary sclerosing cholangitis.
Poch T, Bahn J, Casar C, Krause J, Evangelakos I, Gilladi H, Kunzmann LK, Laschtowitz A, Iuso N, Schäfer AM, Liebig LA, Steinmann S, Sebode M, Folseraas T, Engesæter LK, Karlsen TH, Franke A, Hubner N, Schlein C, Galun E, Huber S, Lohse AW, Gagliani N, Schwinge D, Schramm C., Free PMC Article | 08/16/2024 |
| The role of Bach2 in regulating CD8 + T cell development and function. | The role of Bach2 in regulating CD8 + T cell development and function.
Weng X, Zheng M, Liu Y, Lou G., Free PMC Article | 03/13/2024 |
| Exploring novel functions of BACH2 in the acquisition of antigen-specific antibodies. | Exploring novel functions of BACH2 in the acquisition of antigen-specific antibodies.
Ochiai K, Igarashi K. | 05/30/2023 |
| Bach2 in CD4[+] T cells from SLE patients modulates B-cell differentiation and IgG production. | Bach2 in CD4(+) T cells from SLE patients modulates B-cell differentiation and IgG production.
Long D, Yang B, Yang M, Xiong F, Zhu X, Tan Y, Wu H. | 04/14/2023 |
| BACH2 restricts NK cell maturation and function, limiting immunity to cancer metastasis. | BACH2 restricts NK cell maturation and function, limiting immunity to cancer metastasis.
Imianowski CJ, Whiteside SK, Lozano T, Evans AC, Benson JD, Courreges CJF, Sadiyah F, Lau CM, Zandhuis ND, Grant FM, Schuijs MJ, Vardaka P, Kuo P, Soilleux EJ, Yang J, Sun JC, Kurosaki T, Okkenhaug K, Halim TYF, Roychoudhuri R., Free PMC Article | 10/15/2022 |
| Correlation of the transcription factors IRF4 and BACH2 with the abnormal NFATC1 expression in T cells from chronic myeloid leukemia patients. | Correlation of the transcription factors IRF4 and BACH2 with the abnormal NFATC1 expression in T cells from chronic myeloid leukemia patients.
Zhang Y, Zeng X, Zha X, Lai J, Tan G, Chen S, Yu X, Li Y, Xu L. | 05/21/2022 |
| CRISPR/Cas9-Mediated Insertion of HIV Long Terminal Repeat within BACH2 Promotes Expansion of T Regulatory-like Cells. | CRISPR/Cas9-Mediated Insertion of HIV Long Terminal Repeat within BACH2 Promotes Expansion of T Regulatory-like Cells.
Christian ML, Dapp MJ, Scharffenberger SC, Jones H, Song C, Frenkel LM, Krumm A, Mullins JI, Rawlings DJ., Free PMC Article | 04/16/2022 |
| Transcriptional behavior of the HIV-1 promoter in context of the BACH2 prominent proviral integration gene. | Transcriptional behavior of the HIV-1 promoter in context of the BACH2 prominent proviral integration gene.
Hamann MV, Ehmele P, Verdikt R, Bialek-Waldmann JK, Virdi S, Günther T, Van Lint C, Grundhoff A, Hauber J, Lange UC. | 03/12/2022 |
| BACH2 inhibition reverses beta cell failure in type 2 diabetes models. | BACH2 inhibition reverses β cell failure in type 2 diabetes models.
Son J, Ding H, Farb TB, Efanov AM, Sun J, Gore JL, Syed SK, Lei Z, Wang Q, Accili D, Califano A., Free PMC Article | 01/8/2022 |
| MiR-150-5p regulate T cell activation in severe aplastic anemia by targeting Bach2. | MiR-150-5p regulate T cell activation in severe aplastic anemia by targeting Bach2.
Li Y, Yu J, Wang F, Guo R, Xing H, Chen Y, Chen D, Xie X, Wan D, Jiang Z. | 11/27/2021 |
| Interaction of BACH2 with FUS promotes malignant progression of glioma cells via the TSLNC8-miR-10b-5p-WWC3 pathway. | Interaction of BACH2 with FUS promotes malignant progression of glioma cells via the TSLNC8-miR-10b-5p-WWC3 pathway.
Yang Y, Liu X, Zheng J, Xue Y, Liu L, Ma J, Wang P, Yang C, Wang D, Shao L, Ruan X, Liu Y., Free PMC Article | 11/13/2021 |
| Polymorphism in BACH2 gene is a marker of polyglandular autoimmunity. | Polymorphism in BACH2 gene is a marker of polyglandular autoimmunity.
Fichna M, Żurawek M, Słomiński B, Sumińska M, Czarnywojtek A, Rozwadowska N, Fichna P, Myśliwiec M, Ruchała M., Free PMC Article | 10/30/2021 |
| Up-regulated circBACH2 contributes to cell proliferation, invasion, and migration of triple-negative breast cancer. | Up-regulated circBACH2 contributes to cell proliferation, invasion, and migration of triple-negative breast cancer.
Wang X, Xue B, Zhang Y, Guo G, Duan X, Dou D., Free PMC Article | 10/16/2021 |
| Whole genome sequencing identifies variants associated with sarcoidosis in a family with a high prevalence of sarcoidosis. | Whole genome sequencing identifies variants associated with sarcoidosis in a family with a high prevalence of sarcoidosis.
Fritz D, Ferwerda B, Brouwer MC, van de Beek D., Free PMC Article | 08/21/2021 |
| BACH2-mediated FOS confers cytarabine resistance via stromal microenvironment alterations in pediatric ALL. | BACH2-mediated FOS confers cytarabine resistance via stromal microenvironment alterations in pediatric ALL.
Zhang H, Zhang R, Zheng X, Sun M, Fan J, Fang C, Tian X, Zheng H., Free PMC Article | 03/20/2021 |
| MiR-31 promotes Th22 differentiation through targeting Bach2 in coronary heart disease. | MiR-31 promotes Th22 differentiation through targeting Bach2 in coronary heart disease.
Huang R, Chen X, Long Y, Chen R., Free PMC Article | 09/19/2020 |
| BACH2 was associated with systemic lupus erythematosus disease activity, regulated the function of CD4(+) CD45RA(-) Foxp3(l) degrees cytokine-secreting T cells, and promoted B-cells response | BACH2 regulates the function of human CD4(+) CD45RA(-) Foxp3(l) ° cytokine-secreting T cells and promotes B-cell response in systemic lupus erythematosus.
Zheng Y, Lu Y, Huang X, Han L, Chen Z, Zhou B, Ma Y, Xie G, Yang J, Bian B, Li L, Nie H, Pan X, Shen L. | 08/1/2020 |
| The BACH2 rs11755527 SNP seems not to be associated with Type 1 diabetes mellitus in a Brazilian population. | The rs11755527 polymorphism in the BACH2 gene and type 1 diabetes mellitus: case control study in a Brazilian population.
Dieter C, Lemos NE, Dorfman LE, Duarte GCK, Assmann TS, Crispim D., Free PMC Article | 07/18/2020 |
| Study reveal a critical role of Bach2 in regulating T cell biology and the correlation with these immune-mediated diseases. | The Critical Role of Bach2 in Shaping the Balance between CD4(+) T Cell Subsets in Immune-Mediated Diseases.
Yang L, Chen S, Zhao Q, Sun Y, Nie H., Free PMC Article | 07/11/2020 |
| BACH2 rs3757247 is associated with insulin-triggered type 1 diabetes. | Variants in the BACH2 and CLEC16A gene might be associated with susceptibility to insulin-triggered type 1 diabetes.
Onuma H, Kawamura R, Tabara Y, Yamashita M, Ohashi J, Kawasaki E, Imagawa A, Yamada Y, Chujo D, Takahashi K, Suehiro T, Takata Y, Osawa H, Makino H., Free PMC Article | 04/18/2020 |
| A BACH2 Gene Variant Is Associated with Postoperative Recurrence of Crohn's Disease | A BACH2 Gene Variant Is Associated with Postoperative Recurrence of Crohn's Disease.
Laffin MR, Fedorak RN, Wine E, Dicken B, Madsen KL. | 09/7/2019 |
| The results suggest a critical role for Bach2 in regulating Th2 cell differentiation and the subsequent onset of chronic type 2 inflammation. | The critical role of Bach2 in regulating type 2 chronic airway inflammation.
Yamashita M, Kuwahara M. | 08/10/2019 |
| Results strongly indicate that the MGAT3 and BACH2 genes play an important role in IBD pathogenesis and suggest a possible disease pathway mediated by the pro-inflammatory properties of IgG antibodies acquired by alterations in Fc glycosylation. | Promoter methylation of the MGAT3 and BACH2 genes correlates with the composition of the immunoglobulin G glycome in inflammatory bowel disease.
Klasić M, Markulin D, Vojta A, Samaržija I, Biruš I, Dobrinić P, Ventham NT, Trbojević-Akmačić I, Šimurina M, Štambuk J, Razdorov G, Kennedy NA, Satsangi J, Dias AM, Pinho S, Annese V, Latiano A, D'Inca R, IBD consortium, Lauc G, Zoldoš V., Free PMC Article | 05/25/2019 |