| Expression of Cholinergic Markers and Characterization of Splice Variants during Ontogenesis of Rat Dorsal Root Ganglia Neurons. | Expression of Cholinergic Markers and Characterization of Splice Variants during Ontogenesis of Rat Dorsal Root Ganglia Neurons.
Corsetti V, Perrone-Capano C, Salazar Intriago MS, Botticelli E, Poiana G, Augusti-Tocco G, Biagioni S, Tata AM., Free PMC Article | 06/26/2021 |
| VACHT is inserted into the presynaptic membrane during synaptic vesicles' exocytosis, removed during their endocytotic recycling, and plays a role in non-quantal secretion of acetylcholine. | Increased non-quantal release of acetylcholine after inhibition of endocytosis by methyl-β-cyclodextrin: the role of vesicular acetylcholine transporter.
Petrov AM, Naumenko NV, Uzinskaya KV, Giniatullin AR, Urazaev AK, Zefirov AL. | 02/4/2012 |
| Sympathetic preganlionics segregate mENK from VAChT and ChAT; most of the subset of mENKergic varicosities negative for VAChT also do not express Syn, suggesting a different vesicular pattern in these sympathetic preganglionic varicosities. | Segregation of met-enkephalin from vesicular acetylcholine transporter and choline acetyltransferase in sympathetic preganglionic varicosities mostly lacking synaptophysin and synaptotagmin.
Sámano C, Zetina ME, Cifuentes F, Morales MA. | 01/21/2010 |
| results suggest that in rodent prefrontal cortex, the alpha7nAChR plays a major role in modulation of the postsynaptic excitation in spiny dendrites in contact with vesicular acetylcholine transporter containing axons | Spatial and intracellular relationships between the alpha7 nicotinic acetylcholine receptor and the vesicular acetylcholine transporter in the prefrontal cortex of rat and mouse.
Duffy AM, Zhou P, Milner TA, Pickel VM., Free PMC Article | 01/21/2010 |
| VAChT concentrations were increased in the brain of control SHR compared to age-matched normotensive Wistar-Kyoto rats. | Vesicular acetylcholine transporter (VAChT) in the brain of spontaneously hypertensive rats (SHR): effect of treatment with an acetylcholinesterase inhibitor.
Tayebati SK, Di Tullio MA, Amenta F. | 01/21/2010 |
| These results made [125I]-( R,R)-5-AOIBV inferior to [125I]-IBVM for the VAChT exploration in vivo. | (E)-[125I]-5-AOIBV: a SPECT radioligand for the vesicular acetylcholine transporter.
Emond P, Mavel S, Zea-Ponce Y, Kassiou M, Garreau L, Bodard S, Drossard ML, Chalon S, Guilloteau D. | 01/21/2010 |
| During VAChT trafficking, the C-terminal dileucine-containing motif is sufficient as a dual signal for both internalization and synaptic vesicle targeting. | Dileucine motif is sufficient for internalization and synaptic vesicle targeting of vesicular acetylcholine transporter.
Colgan L, Liu H, Huang SY, Liu YJ. | 01/21/2010 |
| 18.0 mg/kg dose of chlorpyrifos was associated with (brain region-dependent) decreases in nerve growth factor receptors and cholinergic proteins including the vesicular acetylcholine transporter | Chronic, intermittent exposure to chlorpyrifos in rats: protracted effects on axonal transport, neurotrophin receptors, cholinergic markers, and information processing.
Terry AV Jr, Gearhart DA, Beck WD Jr, Truan JN, Middlemore ML, Williamson LN, Bartlett MG, Prendergast MA, Sickles DW, Buccafusco JJ. | 01/21/2010 |
| VAChT interacts with clathrin-associated adaptor complexes AP-1 and AP-2 | The vesicular acetylcholine transporter interacts with clathrin-associated adaptor complexes AP-1 and AP-2.
Kim MH, Hersh LB. | 01/21/2010 |
| A model for VAChT is suggested in which the known ion pair between lysine in transmembrane domain(TMD)II and aspartate in TMDXI controls the conformation or relative position of TMDXI, which in turn controls additional TMDs in the VAChT carboxy-terminal. | Mutational and pH analysis of ionic residues in transmembrane domains of vesicular acetylcholine transporter.
Bravo DT, Kolmakova NG, Parsons SM. | 01/21/2010 |
| This study locates the acetylcholine (ACh) binding site in the vesicular acetylcholine transporter (VAChT) and identifies the amino acid residues linked to the individual binding and rates of the transmembrane reorientation steps of a transport cycle. | Acetylcholine binding site in the vesicular acetylcholine transporter.
Ojeda AM, Kolmakova NG, Parsons SM. | 01/21/2010 |
| VAChT was primarily localized to membranes of small synaptic vesicles in axon terminals | Vesicular acetylcholine transporter in the rat nucleus accumbens shell: subcellular distribution and association with mu-opioid receptors.
Svingos AL, Colago EE, Pickel VM. | 01/21/2010 |
| Semi-quantitative ultrastructural analysis reveals that from 5% to 13% of VAChT-immunoreactive presynaptic profiles contained mu opioid receptor (MOR). Additionally, 7% of VAChT presynaptic profiles directly apposed MOR axons and terminals. | Ultrastructural evidence for mu-opioid modulation of cholinergic pathways in rat dentate gyrus.
Kaplan TJ, Skyers PR, Tabori NE, Drake CT, Milner TA. | 01/21/2010 |